Suchergebnisse - "Kang, Yibin"

Unveiling cancer crosstalk: Mapping complexity across time and space von Kang, Yibin

“… Cancer evolves through dynamic exchanges with its environment, harnessing these interactions to grow, adapt, and transcend the constraints that would otherwise …”
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Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis von Lu, Wei, Kang, Yibin

“… Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-epithelial transition (MET), are fundamental processes in embryonic …”
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Context-dependent EMT programs in cancer metastasis von Aiello, Nicole M, Kang, Yibin

“… Epithelial-mesenchymal transition (EMT) is a developmental process whereby stationary, adherent cells acquire the ability to migrate. EMT is critical for …”
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Tumor cell dissemination: emerging biological insights from animal models and cancer patients von Kang, Yibin, Pantel, Klaus

“… Circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) are increasingly recognized for their potential utility in disease monitoring and …”
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Hypoxia and hypoxia-inducible factors: master regulators of metastasis von Lu, Xin, Kang, Yibin

“… Hypoxia is a common condition found in a wide range of solid tumors and is often associated with poor prognosis. Hypoxia increases tumor glycolysis, …”
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Distinctive properties of metastasis-initiating cells von Celià-Terrassa, Toni, Kang, Yibin

“… Primary tumors are known to constantly shed a large number of cancer cells into systemic dissemination, yet only a tiny fraction of these cells is capable of …”
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How important is EMT for cancer metastasis? von Celià-Terrassa, Toni, Kang, Yibin

“… Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly …”
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Bone marrow niches in the regulation of bone metastasis von Chen, Fenfang, Han, Yujiao, Kang, Yibin

“… The bone marrow has been widely recognised to host a unique microenvironment that facilitates tumour colonisation. Bone metastasis frequently occurs in the …”
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Targeting tumor–stromal interactions in bone metastasis von Esposito, Mark, Kang, Yibin

“… Bone metastasis is a frequent occurrence in late stage solid tumors, including breast cancers, prostate or lung. However, the causes for this proclivity have …”
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Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis von Kang, Yibin

“… Bone metastasis is a frequent occurrence in breast cancer, affecting more than 70% of late stage cancer patients with severe complications such as fracture, …”
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The metastasis-promoting roles of tumor-associated immune cells von Smith, Heath A., Kang, Yibin

“… Tumor metastasis is driven not only by the accumulation of intrinsic alterations in malignant cells, but also by the interactions of cancer cells with various …”
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Regulation of cancer metastasis by cell-free miRNAs von Alečković, Maša, Kang, Yibin

“… MicroRNAs (miRNAs) are integral molecules in the regulation of numerous physiological cellular processes that have emerged as critical players in cancer …”
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Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone von Lu, Xin, Kang, Yibin

“… Metastatic spread of cancer to distant vital organs, including lung and bone, is the overwhelming cause of breast cancer mortality and morbidity. Effective …”
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Emerging therapeutic targets in metastatic progression: A focus on breast cancer von Li, Zhuo, Kang, Yibin

“… Metastasis is the underlying cause of death for the majority of breast cancer patients. Despite significant advances in recent years in basic research and …”
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Cell fusion as a hidden force in tumor progression von Lu, Xin, Kang, Yibin

“… Cell fusion plays an essential role in fertilization, formation of placenta, bone and muscle tissues, immune response, tissue repair, and regeneration …”
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Pre-metastatic niches: organ-specific homes for metastases von Peinado, Héctor, Zhang, Haiying, Matei, Irina R., Costa-Silva, Bruno, Hoshino, Ayuko, Rodrigues, Goncalo, Psaila, Bethan, Kaplan, Rosandra N., Bromberg, Jacqueline F., Kang, Yibin, Bissell, Mina J., Cox, Thomas R., Giaccia, Amato J., Erler, Janine T., Hiratsuka, Sachie, Ghajar, Cyrus M., Lyden, David

“… Key Points Organs of future metastasis are selectively and actively modified by the primary tumour before metastatic spread has occurred. Tumours induce the …”
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Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure von Son, Jinsook, Du, Wen, Esposito, Mark, Shariati, Kaavian, Ding, Hongxu, Kang, Yibin, Accili, Domenico

“… Type 2 diabetes (T2D) is associated with β-cell dedifferentiation. Aldehyde dehydrogenase 1 isoform A3 (ALHD1A3) is a marker of β-cell dedifferentiation and …”
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The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis von Korpal, Manav, Kang, Yibin

“… MicroRNAs (miRNAs) play essential roles in many physiological and pathological processes, including tumor development, by regulating the expression of a …”
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The multifaceted role of MTDH/AEG-1 in cancer progression von Hu, Guohong, Wei, Yong, Kang, Yibin

“… Cancer is the result of the progressive acquisition of multiple malignant traits through the accumulation of genetic or epigenetic alterations. Recent studies …”
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The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2 von Korpal, Manav, Lee, Esther S, Hu, Guohong, Kang, Yibin

“… MicroRNAs are small non-coding RNA molecules that can regulate gene expression by interacting with multiple mRNAs and inducing either translation suppression …”
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