Suchergebnisse - "Kang, Hyun Min"

Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells von Cheng, Yu-Heng, Chen, Yu-Chih, Lin, Eric, Brien, Riley, Jung, Seungwon, Chen, Yu-Ting, Lee, Woncheol, Hao, Zhijian, Sahoo, Saswat, Min Kang, Hyun, Cong, Jason, Burness, Monika, Nagrath, Sunitha, S. Wicha, Max, Yoon, Euisik

“… Molecular analysis of circulating tumor cells (CTCs) at single-cell resolution offers great promise for cancer diagnostics and therapeutics from simple liquid …”
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Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data von Jun, Goo, Flickinger, Matthew, Hetrick, Kurt N, Romm, Jane M, Doheny, Kimberly F, Abecasis, Gonçalo R, Boehnke, Michael, Kang, Hyun Min

“… DNA sample contamination is a serious problem in DNA sequencing studies and may result in systematic genotype misclassification and false positive …”
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Analysis of Fire Propagation in Electrical Cable Trays Using the FLASH-CAT Model von Kang, Hyun-Min, Lee, Jaiho, Moon, Young-Seob, Lee, Ho-Young

“… In this study, a novel fire modeling procedure was proposed for the computational fluid dynamics (CFDs) simulation of electrical cable tray fires for improving …”
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Meta-imputation of transcriptome from genotypes across multiple datasets by leveraging publicly available summary-level data von Liu, Andrew E., Kang, Hyun Min

“… Transcriptome wide association studies (TWAS) can be used as a powerful method to identify and interpret the underlying biological mechanisms behind GWAS by …”
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Accurate Discovery of Expression Quantitative Trait Loci Under Confounding From Spurious and Genuine Regulatory Hotspots von Kang, Hyun Min, Ye, Chun, Eskin, Eleazar

“… In genomewide mapping of expression quantitative trait loci (eQTL), it is widely believed that thousands of genes are trans-regulated by a small number of …”
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A high-resolution association mapping panel for the dissection of complex traits in mice von Bennett, Brian J, Farber, Charles R, Orozco, Luz, Kang, Hyun Min, Ghazalpour, Anatole, Siemers, Nathan, Neubauer, Michael, Neuhaus, Isaac, Yordanova, Roumyana, Guan, Bo, Truong, Amy, Yang, Wen-pin, He, Aiqing, Kayne, Paul, Gargalovic, Peter, Kirchgessner, Todd, Pan, Calvin, Castellani, Lawrence W, Kostem, Emrah, Furlotte, Nicholas, Drake, Thomas A, Eskin, Eleazar, Lusis, Aldons J

“… Systems genetics relies on common genetic variants to elucidate biologic networks contributing to complex disease-related phenotypes. Mice are ideal model …”
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Evaluation of the Urine Albumin-to-Creatinine Ratio (UAC) for Early Renal Disease: A Large-Scale Clinical Study in Cats von Cha, Ye-Eun, Lee, Soo-Yeol, Kang, Min-Hee, Kang, Hyun-Min, Kang, Dong-Jae, Park, Hee-Myung

“… CKD is a leading cause of illness in older cats, but early detection is challenging due to the limitations of conventional biomarkers. This study evaluated the …”
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Diagnostic validation of the urine albumin-to-creatinine ratio for early renal disease in healthy dogs and dogs with chronic kidney disease von Lee, Soo-Yeol, Cha, Ye-Eun, Kang, Hyun-Min, Kang, Dong-Jae, Kang, Min-Hee, Park, Hee-Myung

“… This paper highlights the urine albumin-to-creatinine ratio (UAC) as a valuable biomarker for the early detection of chronic kidney disease (CKD) in dogs. The …”
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Evaluation of circulating IGF-I and IGFBP-3 as biomarkers for tumors in dogs von Song, Doo-Won, Ro, Woong-Bin, Sur, Jung-Hyang, Seung, Byung-Joon, Kang, Hyun-Min, Kim, Jong-Won, Park, See-Hyoung, Park, Hee-Myung

“… Background: Serum-based parameters are considered non-invasive biomarkers for cancer detection. In human studies, insulin-like growth factor-I and II (IGF-I …”
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Microscopic examination of spatial transcriptome using Seq-Scope von Cho, Chun-Seok, Xi, Jingyue, Si, Yichen, Park, Sung-Rye, Hsu, Jer-En, Kim, Myungjin, Jun, Goo, Kang, Hyun Min, Lee, Jun Hee

“… Spatial barcoding technologies have the potential to reveal histological details of transcriptomic profiles; however, they are currently limited by their low …”
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Unified representation of genetic variants von Tan, Adrian, Abecasis, Gonçalo R., Kang, Hyun Min

“… A genetic variant can be represented in the Variant Call Format (VCF) in multiple different ways. Inconsistent representation of variants between variant …”
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An efficient and scalable analysis framework for variant extraction and refinement from population-scale DNA sequence data von Jun, Goo, Wing, Mary Kate, Abecasis, Gonçalo R, Kang, Hyun Min

“… The analysis of next-generation sequencing data is computationally and statistically challenging because of the massive volume of data and imperfect data …”
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Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies von Zhou, Wei, Nielsen, Jonas B., Fritsche, Lars G., Dey, Rounak, Gabrielsen, Maiken E., Wolford, Brooke N., LeFaive, Jonathon, VandeHaar, Peter, Gagliano, Sarah A., Gifford, Aliya, Bastarache, Lisa A., Wei, Wei-Qi, Denny, Joshua C., Lin, Maoxuan, Hveem, Kristian, Kang, Hyun Min, Abecasis, Goncalo R., Willer, Cristen J., Lee, Seunggeun

“… In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks, most binary traits have substantially fewer cases than controls. Both …”
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Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture von Kristjánsdóttir, Katla, Dziubek, Alexis, Kang, Hyun Min, Kwak, Hojoong

“… Enhancer RNAs (eRNA) are unstable non-coding RNAs, transcribed bidirectionally from active regulatory sequences, whose expression levels correlate with …”
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Social relationships enhance the time spent eating and intake of a novel diet in pregnant Hanwoo ( Bos taurus coreanae ) heifers von Shin, Dong-Han, Kang, Hyun-Min, Seo, Seongwon

“… The objective of this study was to evaluate the effects of social relationships on the feed intake, eating behavior, and growth, upon exposure to a novel diet, …”
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Variance component model to account for sample structure in genome-wide association studies von Kang, Hyun Min, Sul, Jae Hoon, Service, Susan K, Zaitlen, Noah A, Kong, Sit-yee, Freimer, Nelson B, Sabatti, Chiara, Eskin, Eleazar

“… Eleazar Eskin and colleagues report a variance component model for correcting for sample structure in association studies. The EMMAX program is publicly …”
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FIVEx: an interactive eQTL browser across public datasets von Kwong, Alan, Boughton, Andrew P, Wang, Mukai, VandeHaar, Peter, Boehnke, Michael, Abecasis, Gonçalo, Kang, Hyun Min

“… Abstract Summary Expression quantitative trait loci (eQTLs) characterize the associations between genetic variation and gene expression to provide insights …”
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Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants von Fu, Wenqing, O’Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Rieder, Mark J., Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., NHLBI Exome Sequencing Project, Akey, Joshua M.

“… Resequencing of genes from individuals of European and African American ancestry indicates that approximately 73% of all protein-coding SNVs and approximately …”
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수정 Starburst 알고리즘과 Homography Normalization을 이용한 시선추적 von 조태훈, 강현민, Cho, Tai-Hoon, Kang, Hyun-Min

“… In this paper, an accurate remote gaze tracking method with two cameras is presented using a modified Starburst algorithm and honography normalization …”
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Evolution and functional impact of rare coding variation from deep sequencing of human exomes von Tennessen, Jacob A, Bigham, Abigail W, O'Connor, Timothy D, Fu, Wenqing, Kenny, Eimear E, Gravel, Simon, McGee, Sean, Do, Ron, Liu, Xiaoming, Jun, Goo, Kang, Hyun Min, Jordan, Daniel, Leal, Suzanne M, Gabriel, Stacey, Rieder, Mark J, Abecasis, Goncalo, Altshuler, David, Nickerson, Deborah A, Boerwinkle, Eric, Sunyaev, Shamil, Bustamante, Carlos D, Bamshad, Michael J, Akey, Joshua M

“… As a first step toward understanding how rare variants contribute to risk for complex diseases, we sequenced 15,585 human protein-coding genes to an average …”
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