Suchergebnisse - "Junker, Ian P."

Ancestral neural circuits potentiate the origin of a female sexual behavior in Drosophila von Li, Minhao, Chen, Dawn S., Junker, Ian P., Szorenyi, Fabianna I., Chen, Guan Hao, Berger, Arnold J., Comeault, Aaron A., Matute, Daniel R., Ding, Yun

“… Courtship interactions are remarkably diverse in form and complexity among species. How neural circuits evolve to encode new behaviors that are functionally …”
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Effects of αTAT1 and HDAC5 on axonal regeneration in adult neurons von Lin, Shen, Sterling, Noelle A., Junker, Ian P., Helm, Courtney T., Smith, George M.

“… The role of posttranslational modifications in axonal injury and regeneration has been widely studied but there has been little consensus over the mechanism by …”
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Compensatory adaptation of parallel motor pathways promotes skilled forelimb recovery after spinal cord injury von Sheikh, Imran S., Keefe, Kathleen M., Sterling, Noelle A., Junker, Ian P., Li, Chen, Chen, Jie, Xu, Xiao-Ming, Kirby, Lynn G., Smith, George M.

“… Skilled forelimb patterning is regulated by the corticospinal tract (CST) with support from brainstem regions. When the CST is lesioned, there is a loss of …”
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Retrogradely Transportable Lentivirus Tracers for Mapping Spinal Cord Locomotor Circuits von Sheikh, Imran S., Keefe, Kathleen M., Sterling, Noelle A., Junker, Ian P., Eneanya, Chidubem I., Liu, Yingpeng, Tang, Xiao-Qing, Smith, George M.

“… Retrograde tracing is a key facet of neuroanatomical studies involving long distance projection neurons. Previous groups have utilized a variety of tools …”
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Changes in the cellular makeup of motor patterning circuits drive courtship song evolution in Drosophila von Ye, Dajia, Walsh, Justin T, Junker, Ian P, Ding, Yun

“… How evolutionary changes in genes and neurons encode species variation in complex motor behaviors is largely unknown. Here, we develop genetic tools that …”
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Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord von Keefe, Kathleen M., Junker, Ian P., Sheikh, Imran S., Campion, Thomas J., Smith, George M.

“… Introducing proteins of interest into cells in the nervous system is challenging due to innate biological barriers that limit access to most molecules …”
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High-resolution single-cell analyses reveal evolutionary constraints and evolvability of sexual circuits in Drosophila von Walsh, Justin T, Junker, Ian P, Chen, Yu-Chieh David, Chen, Yen-Chung, Gifford, Helena, Chen, Dawn S, Ding, Yun

“… Understanding how the cellular and molecular composition of neural circuits evolves to generate species-specific behaviors remains a major challenge in …”
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Viral expression of constitutively active AKT3 induces CST axonal sprouting and regeneration, but also promotes seizures von Campion, Thomas J., Sheikh, Imran S., Smit, Rupert D., Iffland, Philip H., Chen, Jie, Junker, Ian P., Krynska, Barbara, Crino, Peter B., Smith, George M.

“… Increasing the intrinsic growth potential of neurons after injury has repeatedly been shown to promote some level of axonal regeneration in rodent models. One …”
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High-resolution comparative single-cell transcriptomics of doublesex -expressing neurons reveals evolutionary conservation and diversity of sexual circuits in Drosophila von Walsh, Justin, Junker, Ian P, Chen, Yu-Chieh David, Chen, Yen-Chung, Gifford, Helena, Ding, Yun

“… Understanding how the cellular and molecular composition of neural circuits change during evolution is essential for deciphering how behavior evolves. Male …”
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Changes in the cellular makeup of motor patterning circuits drive courtship song evolution in Drosophila von Ye, Dajia, Walsh, Justin T, Junker, Ian P, Ding, Yun

“… How evolutionary changes in genes and neurons encode species variation in complex motor behaviors are largely unknown. Here, we develop genetic tools that …”
Volltext

Ancestral neural circuits potentiate the origin of a female sexual behavior von Li, Minhao, Chen, Dawn S, Junker, Ian P, Szorenyi, Fabianna, Chen, Guan Hao, Berger, Arnold J, Comeault, Aaron A, Matute, Daniel R, Ding, Yun

“… Courtship interactions are remarkably diverse in form and complexity among species. How neural circuits evolve to encode new behaviors that are functionally …”
Volltext

Effects of [alpha]TAT1 and HDAC5 on axonal regeneration in adult neurons von Lin, Shen, Sterling, Noelle A, Junker, Ian P, Helm, Courtney T, Smith, George M

“… The role of posttranslational modifications in axonal injury and regeneration has been widely studied but there has been little consensus over the mechanism by …”
Volltext

Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord von Keefe, Kathleen M., Junker, Ian P., Sheikh, Imran S., Campion, Thomas J., Smith, George M.

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Combined in situ hybridization chain reaction and immunostaining to visualize gene expression in whole-mount Drosophila central nervous systems von Duckhorn, Julia C, Junker, Ian P, Ding, Yun, Shirangi, Troy R

“… Methods to visualize gene expression in the Drosophila central nervous system are important in fly neurogenetic studies. In this chapter, we describe a …”
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