Search Results - "Journal of leukocyte biology"

ICAM‐1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis by Bui, Triet M., Wiesolek, Hannah L., Sumagin, Ronen

“…ICAM‐1 is a cell surface glycoprotein and an adhesion receptor that is best known for regulating leukocyte recruitment from circulation to sites of…”
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Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts by Wang, Jin, Jiang, Mengmeng, Chen, Xin, Montaner, Luis J.

“…Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome‐coronavirus‐2 infection often results from alveolar injury…”
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M2b macrophage polarization and its roles in diseases by Wang, Le‐xun, Zhang, Sheng‐xi, Wu, Hui‐juan, Rong, Xiang‐lu, Guo, Jiao

“…Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of…”
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Monocyte heterogeneity and functions in cancer by Olingy, Claire E., Dinh, Huy Q., Hedrick, Catherine C.

“…Monocytes are innate immune cells of the mononuclear phagocyte system that have emerged as important regulators of cancer development and progression. Our…”
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Mechanisms of natural killer cell‐mediated cellular cytotoxicity by Prager, Isabel, Watzl, Carsten

“…Cellular cytotoxicity, the ability to kill other cells, is an important effector mechanism of the immune system to combat viral infections and cancer…”
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Neutrophils at the crossroads of innate and adaptive immunity by Rosales, Carlos

“…Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly mobilized to sites of inflammation and/or infection. At the…”
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Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non‐responders by Yang, Xiaodong, Su, Bin, Zhang, Xin, Liu, Yan, Wu, Hao, Zhang, Tong

“…The morbidity and mortality of HIV type‐1 (HIV‐1)‐related diseases were dramatically diminished by the grounds of the introduction of potent antiretroviral…”
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Frontline Science: COVID‐19 infection induces readily detectable morphologic and inflammation‐related phenotypic changes in peripheral blood monocytes by Zhang, Dan, Guo, Rui, Lei, Lei, Liu, Hongjuan, Wang, Yawen, Wang, Yili, Qian, Hongbo, Dai, Tongxin, Zhang, Tianxiao, Lai, Yanjun, Wang, Jingya, Liu, Zhiqiang, Chen, Tianyan, He, Aili, O'Dwyer, Michael, Hu, Jinsong

“…Excessive monocyte/macrophage activation with the development of a cytokine storm and subsequent acute lung injury, leading to acute respiratory distress…”
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The vitals of NETs by Tan, Chuyi, Aziz, Monowar, Wang, Ping

“…Neutrophils produce neutrophil extracellular traps (NETs) by expelling their extracellular chromatin embedded with citrullinated histone H3, myeloperoxidase,…”
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Angiogenesis and wound repair: when enough is enough by DiPietro, Luisa A.

“…Review on novel concepts in wound angiogenesis; although more capillaries are generally considered better, new studies suggest otherwise. All animals heal, and…”
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NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma by McKee, Chloe M., Coll, Rebecca C.

“…The NLRP3 (NOD‐, LRR‐, and pyrin domain‐containing protein 3) inflammasome is an immunological sensor that detects a wide range of microbial‐ and host‐derived…”
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Natural products and their derivatives: Promising modulators of tumor immunotherapy by Deng, Li‐Juan, Qi, Ming, Li, Nan, Lei, Yu‐He, Zhang, Dong‐Mei, Chen, Jia‐Xu

“…A wealth of evidence supports the role of tumor immunotherapy as a vital therapeutic option in cancer. In recent decades, accumulated studies have revealed the…”
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Biological role of granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) on cells of the myeloid lineage by Ushach, Irina, Zlotnik, Albert

“…Review on M‐CSF and GM‐CSF as homeostatic vs. inflammatory cytokine. M‐CSF and GM‐CSF are 2 important cytokines that regulate macrophage numbers and function…”
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Keratinocyte: A trigger or an executor of psoriasis? by Ni, Xinhui, Lai, Yuping

“…Psoriasis is a common chronic inflammatory skin disease characterized by abnormal proliferation/differentiation of keratinocytes and excessive immune cell…”
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The PI3K/AKT signaling pathway in regulatory T‐cell development, stability, and function by Pompura, Saige L., Dominguez‐Villar, Margarita

“…The PI3K/AKT signaling pathway is an essential node in mammalian cells that controls cell growth, migration, proliferation, and metabolism. During the last…”
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Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality by Frydrych, Lynn M., Bian, Guowu, O'Lone, David E., Ward, Peter A., Delano, Matthew J.

“…Obesity and type 2 diabetes mellitus (T2D) are global pandemics. Worldwide, the prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D…”
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Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity by Orning, Pontus, Lien, Egil

“…Caspase‐8 is an apical caspase involved in the programmed form of cell death called apoptosis that is critically important for mammalian development and…”
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Extracellular CIRP (eCIRP) and inflammation by Aziz, Monowar, Brenner, Max, Wang, Ping

“…Cold‐inducible RNA‐binding protein (CIRP) was discovered 2 decades ago while studying the mechanism of cold stress adaptation in mammals. Since then, the role…”
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IFNγ‐mediated repression of system xc− drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells by Kong, Rui, Wang, Nan, Han, Wei, Bao, Wen, Lu, Jie

“…IFNγ released from CD8+ T cells or natural killer cells plays a crucial role in antitumor host immunity. Several studies have found that IFNγ is involved in…”
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Innate immune receptors in platelets and platelet‐leukocyte interactions by Dib, Paula Ribeiro Braga, Quirino‐Teixeira, Anna Cecíllia, Merij, Laura Botelho, Pinheiro, Mariana Brandi Mendonça, Rozini, Stephane Vicente, Andrade, Fernanda Brandi, Hottz, Eugenio Damaceno

“…Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major inflammatory effector cells that can influence both innate and…”
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