Suchergebnisse - "Jones, Brian T."

Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim von Su, Lijing, Wang, Ying, Wang, Junmei, Mifune, Yuto, Morin, Matthew D, Jones, Brian T, Moresco, Eva Marie Y, Boger, Dale L, Beutler, Bruce, Zhang, Hong

“… Diprovocim is a recently discovered exceptionally potent, synthetic small molecule agonist of TLR2/TLR1 and has shown significant adjuvant activity in …”
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Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists von Morin, Matthew D., Wang, Ying, Jones, Brian T., Mifune, Yuto, Su, Lijing, Shi, Hexin, Moresco, Eva Marie Y., Zhang, Hong, Beutler, Bruce, Boger, Dale L.

“… A screen conducted with nearly 100000 compounds and a surrogate functional assay for stimulation of an immune response that measured the release of TNF-alpha …”
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Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice von Wang, Ying, Su, Lijing, Morin, Matthew D, Jones, Brian T, Mifune, Yuto, Shi, Hexin, Wang, Kuan-Wen, Zhan, Xiaoming, Liu, Aijie, Wang, Jianhui, Li, Xiaohong, Tang, Miao, Ludwig, Sara, Hildebrand, Sara, Zhou, Kejin, Siegwart, Daniel J, Moresco, Eva Marie Y, Zhang, Hong, Boger, Dale L, Beutler, Bruce

“… Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of …”
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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS von Wang, Ying, Su, Lijing, Morin, Matthew D, Jones, Brian T, Whitby, Landon R, Surakattula, Murali M R P, Huang, Hua, Shi, Hexin, Choi, Jin Huk, Wang, Kuan-wen, Moresco, Eva Marie Y, Berger, Michael, Zhan, Xiaoming, Zhang, Hong, Boger, Dale L, Beutler, Bruce

“… Structurally disparate molecules reportedly engage and activate Toll-like receptor (TLR) 4 and other TLRs, yet the interactions that mediate binding and …”
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Supplemental reading interventions implemented by paraprofessionals: A meta‐analysis von Jones, Brian T., Erchul, William P., Geraghty, Cathleen A.

“… Preventative and intensive reading intervention can be administered to at‐risk students in a systematic way to help facilitate gains on literacy outcomes …”
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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells von Picco, Gabriele, Rao, Yanhua, Al Saedi, Angham, Lee, Yang, Vieira, Sara F, Bhosle, Shriram, May, Kieron, Herranz-Ors, Carmen, Walker, Samantha J, Shenje, Raynold, Dincer, Cansu, Gibson, Freddy, Banerjee, Ruby, Hewitson, Zoe, Werner, Thilo, Cottom, Joshua E, Peng, Yang, Deng, Nanhua, Zhang, Youyou, Nartey, Eldridge N, Nickels, Leng, Landis, Philip, Conticelli, Daniela, McCarten, Katrina, Bush, Jacob, Sharma, Mamta, Lightfoot, Howard, House, David, Milford, Emma, Grant, Emma K, Glogowski, Michal P, Wagner, Craig D, Bantscheff, Marcus, Rutkowska-Klute, Anna, Zappacosta, Francesca, Pettinger, Jonathan, Barthorpe, Syd, Eberl, H Christian, Jones, Brian T, Schneck, Jessica L, Murphy, Dennis J, Voest, Emile E, Taygerly, Joshua P, DeMartino, Michael P, Coelho, Matthew A, Houseley, Jonathan, Sharma, Geeta, Schwartz, Benjamin, Garnett, Mathew J

“… Microsatellite-unstable (MSI) cancers require WRN helicase to resolve replication stress due to expanded DNA (TA)n dinucleotide repeats. WRN is a promising …”
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Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists von Morin, Matthew D., Wang, Ying, Jones, Brian T., Su, Lijing, Surakattula, Murali M. R. P., Berger, Michael, Huang, Hua, Beutler, Elliot K., Zhang, Hong, Beutler, Bruce, Boger, Dale L.

“… Herein, we report studies leading to the discovery of the neoseptins and a comprehensive examination of the structure activity relationships (SARs) of this new …”
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Total synthesis of propolisbenzofuran B von Jones, Brian T., Avetta, Christopher T., Thomson, Regan J.

“… The first total synthesis of propolisbenzofuran B, a bioactive natural product isolated from honeybee propolis resin, is reported. The convergent synthesis …”
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Systematic CHAAOS: Teaching Vocabulary in English/Language Arts Special Education Classes in Middle School von O’Connor, Rollanda E., Sanchez, Victoria M., Jones, Brian T., Suchlit, Luisana, Youkhanna, Valencia, Beach, Kristen D., Widaman, Keith

“… In this multi-year study, we taught English/Language Arts teachers of students with learning disabilities in middle school to incorporate 15 min of daily …”
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Teaching Academic Vocabulary to Sixth-Grade Students With Disabilities von O’Connor, Rollanda E., Beach, Kristen D., Sanchez, Victoria M., Kim, Joyce J., Knight-Teague, Kerri, Orozco, Guadalupe, Jones, Brian T.

“… Adolescents with disabilities have great difficulty with academic content in middle school, and their teachers have difficulty teaching them to understand and …”
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Elimination of Butylcycloheptylprodigiosin as a Known Natural Product Inspired by an Evolutionary Hypothesis for Cyclic Prodigiosin Biosynthesis von Jones, Brian T., Hu, Dennis X., Savoie, Brett M., Thomson, Regan J.

“… The cyclic prodigiosins are an important family of bioactive natural products that continue to be the subject of numerous structural, synthetic, and …”
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The Social Ecology of Homelessness: Exploring the Dynamics of Engagement among Homeless Street Adults von Jones, Brian T.

“… The study examines interaction patterns of homeless populations. The study explores how this population interacts within a given environment. The current study …”
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Oxidative Carbon-Carbon Bond Formation via Allyldimethylsilyl Enol Ethers von Konkol, Leah C., Jones, Brian T., Thomson, Regan J.

“… A method for the oxidative alkylation of ketones through intramolecular allyl-group transfer within preformed allyldimethylsilyl enol ethers Is reported. A …”
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α-Terpineol reactions with the nitrate radical: Rate constant and gas-phase products von Jones, Brian T., Ham, Jason E.

“… The bimolecular rate constant of k NO 3 + α-terpineol (16 ± 4) × 10 −12 cm 3 molecule −1 s −1 was measured using the relative rate technique for the reaction …”
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Policy lessons from the evolution of a community-based approach to wildlife management, Kunene Region, Namibia von Jones, Brian T. B.

“… A community‐based natural resource management project in the arid Kunene Region of Namibia has evolved over time from a focus on halting poaching to ensuring …”
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Endoluminal reconstruction of the canine common biliary duct von Zografakis, John G, Jones, Brian T, Ravichardran, Pars, Evancho-Chapman, M.Michelle, Schmidt, Steven P, Arends, Dane, Funk, Karla M, Gingras, Peter

“… Extrahepatic biliary duct injuries such as transections, stenoses, and biliary leaks are well-known complications of upper abdominal surgeries. The …”
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Total synthesis of propolisbenzofuran BElectronic supplementary information (ESI) available: Experimental procedures and spectral data (NMR, MS, IR) for all new compounds. See DOI: 10.1039/c4sc00356j von Jones, Brian T, Avetta, Christopher T, Thomson, Regan J

“… The first total synthesis of propolisbenzofuran B, a bioactive natural product isolated from honeybee propolis resin, is reported. The convergent synthesis …”
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Decreased Reception of Nonverbal Cues in Heroin Addicts von Giannini, A. James, Jones, Brian T.

“… The ability to interpret nonverbal cues was tested in 15 young, white American male heroin addicts who were not intoxicated. When their responses were compared …”
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Anxiogenic effects of generated ambient cations--a preliminary study von Giannini, A J, Jones, B T, Loiselle, R H, Price, W A

“… The existence of the putative "serotonin irritation syndrome" (SIS) was tested in a human population. Volunteers were exposed to a highly cationized …”
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Clients for Sale: Planners must recognize and deal with potential conflicts when they get ready to sell their firms von Jones, Brian T

“… When it comes time to sell a financial planning business, planners may not be putting their clients' interests first. Financial planning professionals have a …”
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