Suchergebnisse - "Jakasa, Ivone"
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Skin biomarkers predict development of atopic dermatitis in infancy
ISSN: 0105-4538, 1398-9995, 1398-9995Veröffentlicht: Denmark Blackwell Publishing Ltd 01.03.2023Veröffentlicht in Allergy (Copenhagen) (01.03.2023)“… Background There is currently no insight into biomarkers that can predict the onset of pediatric atopic dermatitis (AD). Methods Nested in a prospective birth …”
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The Influence of Psychological Stress on the Levels of the Skin's Natural Moisturizing Factor in Croatian Medical Students
ISSN: 1847-6538, 1847-6538Veröffentlicht: Croatia 01.11.2024Veröffentlicht in Acta dermatovenerologica Croatica (01.11.2024)“… Psychological stress may affect skin barrier homeostasis and slow down its recovery. Therefore, we aimed to examine the association between psychological …”
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Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
ISSN: 0091-6749, 1097-6825, 1097-6825Veröffentlicht: New York, NY Elsevier Inc 01.04.2012Veröffentlicht in Journal of allergy and clinical immunology (01.04.2012)“… Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural moisturizing factor (NMF) components and consequent increased SC pH. Because higher pH …”
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Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice
ISSN: 1523-1747, 1523-1747Veröffentlicht: United States 01.03.2020Veröffentlicht in Journal of investigative dermatology (01.03.2020)“… Abundant corneocyte surface protrusions, observed in patients with atopic dermatitis with filaggrin loss-of-function mutations, are inversely associated with …”
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Differences in Occurrence, Risk Factors and Severity of Early-onset Atopic Dermatitis among Preterm and Term Children
ISSN: 0001-5555, 1651-2057, 1651-2057Veröffentlicht: Sweden Medical Journals Sweden 15.06.2022Veröffentlicht in Acta dermato-venereologica (15.06.2022)“… This prospective birth cohort followed 150 preterm and 300 term newborns during the first year of life to assess possible differences in risk factors, age at …”
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South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin
ISSN: 0091-6749, 1097-6825, 1097-6825Veröffentlicht: New York, NY Elsevier Inc 01.01.2014Veröffentlicht in Journal of allergy and clinical immunology (01.01.2014)“… FLG mutations lead to reduced levels of filaggrin degradation products in the SC in a dose-dependent fashion.5 It has been shown that moderate-to-severe AD …”
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Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis
ISSN: 2379-3708, 2379-3708Veröffentlicht: United States American Society for Clinical Investigation 08.05.2024Veröffentlicht in JCI insight (08.05.2024)“… Atopic dermatitis (AD) is an inflammatory skin condition with a childhood prevalence of up to 25%. Microbial dysbiosis is characteristic of AD, with …”
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Similar Skin Barrier Function in Persons with Type 1 Diabetes Compared with Healthy Controls
ISSN: 2667-0267, 2667-0267Veröffentlicht: Netherlands Elsevier Inc 01.07.2023Veröffentlicht in JID innovations (01.07.2023)“… Contact dermatitis because of use of diabetes devices is frequent in individuals with type 1 diabetes (TD1), especially in the pediatric age group, but the …”
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Exploring the potential of stratum corneum biomarkers for assessing psychological distress in health care workers: An observational pilot study
ISSN: 2398-8835, 2398-8835Veröffentlicht: United States John Wiley & Sons, Inc 01.01.2024Veröffentlicht in Health science reports (01.01.2024)“… Backgrounds The detection of biomarkers of a stress response in the stratum corneum (SC) could be used as objective assessment of early stress symptoms and …”
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Barrier function and natural moisturizing factor levels after cumulative exposure to a fruit-derived organic acid and a detergent: different outcomes in atopic and healthy skin and relevance for occupational contact dermatitis in the food industry
ISSN: 0105-1873, 1600-0536, 1600-0536Veröffentlicht: Oxford, UK Blackwell Publishing Ltd 01.12.2015Veröffentlicht in Contact dermatitis (01.12.2015)“… Fruit-derived organic compounds and detergents are relevant exposure factors for occupational contact dermatitis in the food industry. Although individuals …”
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Skin Barrier– and Immune Response–Related Biomarkers of Solar UVR Exposure Comparing Indoor and Outdoor Workers
ISSN: 2667-0267, 2667-0267Veröffentlicht: Netherlands Elsevier Inc 01.05.2024Veröffentlicht in JID innovations (01.05.2024)“… Outdoor workers have increased risk of developing keratinocyte cancer due to accumulated skin damage resulting from chronic and excessive exposure to UVR. This …”
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Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis
ISSN: 2398-502X, 2398-502XVeröffentlicht: London Wellcome Trust Limited 2020Veröffentlicht in Wellcome open research (2020)“… Background: Impaired skin barrier is an important etiological factor in atopic dermatitis (AD). The structural protein filaggrin (FLG) plays a major role in …”
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Blockade of interleukin-13 signalling improves skin barrier function and biology in patients with moderate-to-severe atopic dermatitis
ISSN: 0007-0963, 1365-2133, 1365-2133Veröffentlicht: Oxford Oxford University Press 01.09.2024Veröffentlicht in British journal of dermatology (1951) (01.09.2024)“… Background Interleukin (IL)-13 is a key driver of inflammation and barrier dysfunction in atopic dermatitis (AD). While there is robust evidence that …”
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Evaluation of an intervention to increase topical sunscreen use in German outdoor workers: study protocol for the non-randomised controlled intervention study ProtExSun
ISSN: 2044-6055, 2044-6055Veröffentlicht: England British Medical Journal Publishing Group 05.10.2025Veröffentlicht in BMJ open (05.10.2025)“… IntroductionSquamous cell carcinoma and multiple actinic keratoses caused by solar ultraviolet radiation (UVR) are among the most frequently recognised …”
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Filaggrin and Skin Barrier Function
ISSN: 1662-2944, 1662-2944Veröffentlicht: Switzerland 01.01.2016Veröffentlicht in Current problems in dermatology (01.01.2016)“… The skin barrier function is greatly dependent on the structure and composition of the uppermost layer of the epidermis, the stratum corneum (SC), which is …”
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Inflammatory, oxidative and DNA damage status in vegetarians: is the future of human diet green?
ISSN: 1040-8398, 1549-7852, 1549-7852Veröffentlicht: United States Taylor & Francis 15.07.2023Veröffentlicht in Critical reviews in food science and nutrition (15.07.2023)“… The health benefit of a vegetarian diet is still under debate as it may result in a higher intake of some beneficial micronutrients, while others may be …”
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Research Techniques Made Simple: Stratum Corneum Tape Stripping
ISSN: 1523-1747, 1523-1747Veröffentlicht: United States 01.05.2021Veröffentlicht in Journal of investigative dermatology (01.05.2021)“… Stratum corneum (SC)-derived biomarkers can provide relevant information on the skin's antimicrobial, physical, and immunological barriers. The SC is easily …”
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Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study
ISSN: 2044-6055, 2044-6055Veröffentlicht: England British Medical Journal Publishing Group 17.02.2023Veröffentlicht in BMJ open (17.02.2023)“… IntroductionLesional skin of atopic dermatitis (AD) is often colonised by Staphylococcus aureus and the bacterial abundance increases during a flare. However, …”
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The role of skin barrier in occupational contact dermatitis
ISSN: 0906-6705, 1600-0625, 1600-0625Veröffentlicht: Denmark Wiley Subscription Services, Inc 01.08.2018Veröffentlicht in Experimental dermatology (01.08.2018)“… Skin diseases represent one of the most common work‐related diseases and may have a detrimental effect on social, personal and occupational aspects of life …”
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Assessment of biomarkers in pediatric atopic dermatitis by tape strips and skin biopsies
ISSN: 0105-4538, 1398-9995, 1398-9995Veröffentlicht: Denmark Blackwell Publishing Ltd 01.05.2022Veröffentlicht in Allergy (Copenhagen) (01.05.2022)“… Background The cytokine profile of atopic dermatitis (AD) depends on age, ethnicity, and disease severity. This study examined biomarkers in children with AD …”
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