Výsledky vyhľadávania - "Jacob, H J"

New physics explanations of aμ in light of the FNAL muon g − 2 measurement Autor Athron, Peter, Balázs, Csaba, Jacob, Douglas H. J., Kotlarski, Wojciech, Stöckinger, Dominik, Stöckinger-Kim, Hyejung

“…A bstract The Fermilab Muon g − 2 experiment recently reported its first measurement of the anomalous magnetic moment a μ FNAL , which is in full agreement…”
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Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells Autor Cepeda, Mario A., Pelling, Jacob J. H., Evered, Caitlin L., Williams, Karla C., Freedman, Zoey, Stan, Ioana, Willson, Jessica A., Leong, Hon S., Damjanovski, Sashko

“…Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a multifunctional protease implicated in metastatic progression ostensibly due to its ability…”
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Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels Autor Cepeda, Mario A., Evered, Caitlin L., Pelling, Jacob J. H ., Damjanovski, Sashko

“…Membrane type-1 matrix metalloproteinase (MT1-MMP, MMP-14) is a unique protease that cleaves extracellular proteins, activates proMMPs, and initiates…”
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Ketogenic-Mimicking Diet as a Therapeutic Modality for Bipolar Disorder: Biomechanistic Rationale and Protocol for a Pilot Clinical Trial Autor Bohnen, Jeffrey, Wigstrom, Travis, Griggs, Alexis, Roytman, Stiven, Paalanen, Noah, Andrews, Hailemicael, Bohnen, Nicolaas, Franklin, Jacob, McInnis, Melvin

“…There is growing interest in the investigation of ketogenic diets as a potential therapy for bipolar disorder. The overlapping pharmacotherapies utilized for…”
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Phase II study of oxaliplatin, fluorouracil, and folinic acid in locally advanced or metastatic gastric cancer patients Autor Louvet, C, André, T, Tigaud, J M, Gamelin, E, Douillard, J Y, Brunet, R, François, E, Jacob, J H, Levoir, D, Taamma, A, Rougier, P, Cvitkovic, E, de Gramont, A

“…To evaluate the efficacy and safety of an oxaliplatin, fluorouracil (5-FU), and folinic acid (FA) combination in patients with metastatic or advanced gastric…”
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Developmental competence and the induction of ectopic proboscises in Drosophila melanogaster Autor Percival-Smith, Anthony, Sivanantharajah, Lovesha, Pelling, Jacob J. H, Teft, Wendy A

“…Developmental competence is the response of a cell(s) to information. Determination of adult labial identity in Drosophila requires Proboscipedia (PB) and Sex…”
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Review: Mechanisms of TIMP-3 accumulation and pathogenesis in Sorsby fundus dystrophy Autor Betts, Jacob H J, Troeberg, Linda

“…Sorsby fundus dystrophy (SFD) is a rare, inherited form of macular degeneration caused by mutations in the gene encoding tissue inhibitor of metalloproteinases…”
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Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancer Autor Bleiberg, H, Conroy, T, Paillot, B, Lacave, A.J, Blijham, G, Jacob, J.H, Bedenne, L, Namer, M, De Besi, P, Gay, F, Collette, L, Sahmoud, T

“…Patients with measurable or evaluable locally advanced or metastatic squamous cell carcinoma of the oesophagus were treated with cisplatin (CDDP), 100 mg/m 2,…”
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The Noncell Autonomous Requirement of Proboscipedia for Growth and Differentiation of the Distal Maxillary Palp during Metamorphosis of Drosophila melanogaster Autor Percival-Smith, Anthony, Ponce, Gabriel, Pelling, Jacob J. H.

“…The Drosophila maxillary palpus that develops during metamorphosis is composed of two elements: the proximal maxillary socket and distal maxillary palp. The…”
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Induction cisplatin–irinotecan followed by concurrent cisplatin–irinotecan and radiotherapy without surgery in oesophageal cancer: multicenter phase II FFCD trial Autor Michel, P, Adenis, A, Fiore, F Di, Boucher, E, Galais, M P, Dahan, L, Mirabel, X, Hamidou, H, Raoul, J L, Jacob, J H, Hellot, M F, Prod'Homme, S, Paillot, B

“…A recent phase I study showed that weekly cisplatin, irinotecan and concurrent radiotherapy can be administered with moderate toxicity in patients with…”
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Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue Autor Green, Jonathan, Tinson, Ryan A.J., Betts, Jacob H.J., Piras, Monica, Pelut, Aylin, Steverding, Dietmar, Wren, Stephen P., Searcey, Mark, Troeberg, Linda

“…[Display omitted] Osteoarthritis is a chronic degenerative joint disease affecting millions of people worldwide, with no disease-modifying drugs currently…”
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Enterprise-wide simultaneous deployment of ambient scribe technology: lessons learned from an academic health system Autor Wright, Aileen P, Nall, Carolynn K, Franklin, Jacob J H, Horst, Sara N, Kumah-Crystal, Yaa A, Wright, Adam T, Mize, Dara E

“…To report on the feasibility of a simultaneous, enterprise-wide deployment of EHR-integrated ambient scribe technology across a large academic health system…”
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Four Biomarkers Linked to Activation of Cluster of Differentiation 8–Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure Autor Leonis, Mike A., Miethke, Alexander G., Fei, Lin, Maynor, Sean, Chapin, Catherine A., Bleesing, Jacob J.H., Alonso, Estella M., Squires, Robert H.

“…Background and Aims Immune dysregulation contributes to the pathogenesis of pediatric acute liver failure (PALF). Our aim was to identify immune activation…”
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A microsatellite genetic linkage map for zebrafish (Danio rerio) Autor Knapik, E W, Goodman, A, Ekker, M, Chevrette, M, Delgado, J, Neuhauss, S, Shimoda, N, Driever, W, Fishman, M C, Jacob, H J

“…We have constructed a zebrafish genetic linkage map consisting of 705 simple sequence-length polymorphism markers (SSLPs). The map covers 2350 centimorgans…”
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A phase II study of oral uracil/ftorafur (UFT®) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer Autor Bennouna, J, Perrier, H, Paillot, B, Priou, F, Jacob, J H, Hebbar, M, Bordenave, S, Seitz, J F, Cvitkovic, F, Dorval, E, Malek, K, Tonelli, D, Douillard, J Y

“…This phase II trial was performed to evaluate the efficacy and tolerability of a new combination of Uracil/Ftorafur (UFT ® )/leucovorin (LV) and oxaliplatin in…”
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A Genomic-Systems Biology Map for Cardiovascular Function Autor Stoll, Monika, Cowley, Allen W., Tonellato, Peter J., Greene, Andrew S., Kaldunski, Mary L., Roman, Richard J., Dumas, Pierre, Schork, Nicholas J., Wang, Zhitao, Jacob, Howard J.

“…With the draft sequence of the human genome available, there is a need to better define gene function in the context of systems biology. We studied 239…”
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Consomic rat model systems for physiological genomics Autor Cowley Jr, A. W., Liang, M., Roman, R. J., Greene, A. S., Jacob, H. J.

“…A consomic rat strain is one in which an entire chromosome is introgressed into the isogenic background of another inbred strain using marker‐assisted…”
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Synergistic QTL interactions between Rf-1 and Rf-3 increase renal damage susceptibility in double congenic rats Autor Van Dijk, S.J., Specht, P.A.C., Lazar, J., Jacob, H.J., Provoost, A.P.

“…The FHH (fawn-hooded hypertensive) rat is a model of hypertension-associated chronic kidney damage. Five interacting quantitative trait loci (QTLs), named…”
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A randomized phase II trial evaluating safety and efficacy of an experimental chemotherapy regimen (irinotecan + oxaliplatin, IRINOX) and two standard arms (LV5 FU2 + irinotecan or LV5 FU2 + oxaliplatin) in first-line metastatic colorectal cancer: a study of the Digestive Group of the Fédération Nationale des Centres de Lutte Contre le Cancer Autor Bécouarn, Y, Senesse, P, Thézenas, S, Boucher, E, Adenis, A, Cany, L, Jacob, J H, Cvitkovic, F, Montoto-Grillot, C, Ychou, M

“…To assess activity and safety of an experimental combination of irinotecan and oxaliplatin (IRINOX) as first-line treatment in advanced colorectal cancer. In…”
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1kW fiber-coupled pump-module at 976nm with 50% efficiency Autor Chin, R H, Dogan, M, Fulghum, S, Jacob, J H, Chin, A K

“…We present a fiber-coupled pump-module emitting more than 1kW of mode-stripped power at 976nm from a detachable 225µm, 0.22NA fiber. The electrical-to-optical…”
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