Výsledky vyhľadávania - "Innes, Barbara A"

Decidual macrophages: key regulators of vascular remodeling in human pregnancy Autor Lash, Gendie E., Pitman, Hedele, Morgan, Hannah L., Innes, Barbara A., Agwu, Chinedu N., Bulmer, Judith N.

“…Decidual macrophages phagocytose apoptotic VSMC during remodeling of the uterine spiral arteries during early human pregnancy. Successful remodeling of the…”
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Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy Autor Lash, Gendie E., Schiessl, Barbara, Kirkley, Maureen, Innes, Barbara A., Cooper, Alix, Searle, Roger F., Robson, Stephen C., Bulmer, Judith N.

“…Remodeling of uterine spiral arteries is critical for the continuation of a successful pregnancy. Uterine natural killer (uNK) cells are the predominant…”
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The role of vascular smooth muscle cell apoptosis and migration during uterine spiral artery remodeling in normal human pregnancy Autor Bulmer, Judith N, Innes, Barbara A, Levey, Joanne, Robson, Stephen C, Lash, Gendie E

“…During human uterine spiral artery (SpA) remodeling, vascular smooth muscle cells (VSMCs) are lost and replaced by fibrinoid, incorporating extravillous…”
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Altered decidual leucocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy Autor Williams, Paula J, Bulmer, Judith N, Searle, Roger F, Innes, Barbara A, Robson, Stephen C

“…Alterations in the balance of leucocyte populations in uterine decidua may lead to the generation of an unfavourable cytokine environment that is associated…”
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Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production Autor Lash, Gendie E, Naruse, Katsuhiko, Robson, Andrew, Innes, Barbara A, Searle, Roger F, Robson, Stephen C, Bulmer, Judith N

“…Uterine natural killer (uNK) cells are a major source of cytokines and angiogenic growth factors (AGFs), with AGF levels decreasing and cytokine levels…”
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Altered vascular smooth muscle cell differentiation in the endometrial vasculature in menorrhagia Autor Biswas Shivhare, Sourima, Bulmer, Judith N, Innes, Barbara A, Hapangama, Dharani K, Lash, Gendie E

“…How does the smooth muscle content and differentiation stage of vascular smooth muscle cells (VSMCs) in endometrial blood vessels change according to the…”
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Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation Autor Lu, Qinsheng, Sun, Dingqian, Shivhare, Sourima Biswas, Hou, Huomei, Bulmer, Judith N., Innes, Barbara A., Hapangama, Dharani K., Lash, Gendie E.

“…Appropriate growth and development of the endometrium across the menstrual cycle is key for a woman’s quality of life and reproductive well-being. Recurrent…”
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Inhibition of Trophoblast Cell Invasion by TGFB1, 2, and 3 Is Associated with a Decrease in Active Proteases Autor Lash, Gendie E, Otun, Harry A, Innes, Barbara A, Bulmer, Judith N, Searle, Roger F, Robson, Stephen C

“…Invasion of extravillous trophoblast cells into the uterus in human pregnancy is tightly regulated. The transforming growth factor-beta (TGFB) family has been…”
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Secretion of cytokines by villous cytotrophoblast and extravillous trophoblast in the first trimester of human pregnancy Autor Naruse, Katsuhiko, Innes, Barbara A., Bulmer, Judith N., Robson, Stephen C., Searle, Roger F., Lash, Gendie E.

“…Cytokines are proposed to play roles in regulation of trophoblast invasion, spiral artery remodeling and immunoregulation during early pregnancy. Secretion of…”
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Effector Activity of Decidual CD8+ T Lymphocytes in Early Human Pregnancy Autor SCAIFE, Paula J, BULMER, Judith N, ROBSON, Stephen C, INNES, Barbara A, SEARLE, Roger F

“…Although CD8 + T lymphocytes are present in human decidua throughout pregnancy, albeit as a minor population in early pregnancy, their role in normal pregnancy…”
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Uterine natural killer cells initiate spiral artery remodeling in human pregnancy Autor Robson, Andrew, Harris, Lynda K, Innes, Barbara A, Lash, Gendie E, Aljunaidy, Mais M, Aplin, John D, Baker, Philip N, Robson, Stephen C, Bulmer, Judith N

“…Uterine spiral artery remodeling is required for successful human pregnancy; impaired remodeling is associated with pregnancy complications, including late…”
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Low Oxygen Concentrations Inhibit Trophoblast Cell Invasion from Early Gestation Placental Explants via Alterations in Levels of the Urokinase Plasminogen Activator System Autor LASH, Gendie E, OTUN, Harry A, INNES, Barbara A, BULMER, Judith N, SEARLE, Roger F, ROBSON, Stephen C

“…Extravillous trophoblast cell (EVT) invasion in early pregnancy occurs in a relatively low-oxygen environment. The role of oxygen in regulation of EVT invasion…”
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Transient loss of endothelial cells in human spiral artery remodelling during early pregnancy: Challenging the dogma Autor Bulmer, Judith N., Innes, Barbara A., Robson, Stephen C., Lash, Gendie E.

“…Spiral artery (SpA) remodelling is essential for a successful pregnancy and is best described by its morphological features; vascular smooth muscle cell…”
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Possible Roles for Folic Acid in the Regulation of Trophoblast Invasion and Placental Development in Normal Early Human Pregnancy Autor WILLIAMS, Paula J, BULMER, Judith N, INNES, Barbara A, BROUGHTON PIPKIN, Fiona

“…In addition to its role in the prevention of neural tube defects, folic acid has many other physiological functions, including cell proliferation, DNA…”
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Localization of angiogenic growth factors and their receptors in the human endometrium throughout the menstrual cycle and in recurrent miscarriage Autor Lash, Gendie E, Innes, Barbara A, Drury, Josephine A, Robson, Stephen C, Quenby, Siobhan, Bulmer, Judith N

“…Angiogenesis is a key feature of endometrial development. Inappropriate endometrial vascular development has been associated with recurrent miscarriage (RM)…”
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Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding–endometrial disorder Autor Biswas Shivhare, Sourima, Lu, Qinsheng, Sun, Dingqian, Hou, Huomei, Bulmer, Judith N., Innes, Barbara A., Hapangama, Dharani K., Lash, Gendie E.

“…What is the expression pattern of platelet-derived growth factor BB (PDGF-BB), and its receptors, across the menstrual cycle in healthy control women and those…”
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Standardisation of uterine natural killer (uNK) cell measurements in the endometrium of women with recurrent reproductive failure Autor Lash, Gendie E., Bulmer, Judith N., Li, Tin Chiu, Innes, Barbara A., Mariee, Najat, Patel, Gnyaneshwari, Sanderson, Jean, Quenby, Siobhan, Laird, Susan M.

“…•There is variation in the numbers of endometrial uNK cell reported by different centres.•We have identified the factors which contribute to these…”
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Altered expression of interleukin-6, interleukin-8 and their receptors in decidua of women with sporadic miscarriage Autor Pitman, Hedele, Innes, Barbara A, Robson, Stephen C, Bulmer, Judith N, Lash, Gendie E

“…Are alterations in decidual expression of interleukin (IL)-6 and IL-8 associated with sporadic miscarriage? IL-6 and IL-8 secretion from decidual uterine…”
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Effects of interleukin-6 on extravillous trophoblast invasion in early human pregnancy Autor Champion, Hedele, Innes, Barbara A, Robson, Stephen C, Lash, Gendie E, Bulmer, Judith N

“…Invasion of uterine tissues by extravillous trophoblast cells (EVT) is essential for successful human pregnancy. EVT invasion is tightly regulated by a number…”
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Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2 Autor Duncan, Christopher J A, Thompson, Benjamin J, Chen, Rui, Rice, Gillian I, Gothe, Florian, Young, Dan F, Lovell, Simon C, Shuttleworth, Victoria G, Brocklebank, Vicky, Corner, Bronte, Skelton, Andrew J, Bondet, Vincent, Coxhead, Jonathan, Duffy, Darragh, Fourrage, Cecile, Livingston, John H, Pavaine, Julija, Cheesman, Edmund, Bitetti, Stephania, Grainger, Angela, Acres, Meghan, Innes, Barbara A, Mikulasova, Aneta, Sun, Ruyue, Hussain, Rafiqul, Wright, Ronnie, Wynn, Robert, Zarhrate, Mohammed, Zeef, Leo A H, Wood, Katrina, Hughes, Stephen M, Harris, Claire L, Engelhardt, Karin R, Crow, Yanick J, Randall, Richard E, Kavanagh, David, Hambleton, Sophie, Briggs, Tracy A

“…Excessive type I interferon (IFNα/β) activity is implicated in a spectrum of human disease, yet its direct role remains to be conclusively proven. We…”
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