Search Results - "Infection and immunity"

Extracellular Vesicle Biogenesis and Functions in Gram-Positive Bacteria by Briaud, Paul, Carroll, Ronan K

“…Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells. Bacterial membrane vesicles were discovered over 60…”
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Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery by Urish, Kenneth L, Cassat, James E

“…Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial pathogens into the skeleton. Bacterial osteomyelitis is notoriously…”
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Sex and Gender Differences in Bacterial Infections by Dias, Sara P, Brouwer, Matthijs C, van de Beek, Diederik

“…There is a growing awareness of the importance of sex and gender in medicine and research. Women typically have stronger immune responses to self and foreign…”
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Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies by Mangalea, Mihnea R, Duerkop, Breck A

“…Bacteria that cause life-threatening infections in humans are becoming increasingly difficult to treat. In some instances, this is due to intrinsic and…”
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Living in Your Skin: Microbes, Molecules, and Mechanisms by Swaney, Mary Hannah, Kalan, Lindsay R

“…Human skin functions as a physical, chemical, and immune barrier against the external environment while also providing a protective niche for its resident…”
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Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis by Gonzalez-Ferrer, Shekina, Peñaloza, Hernán F, Budnick, James A, Bain, William G, Nordstrom, Hayley R, Lee, Janet S, Van Tyne, Daria

“…are Gram-negative facultative anaerobes that are found within host-associated commensal microbiomes, but they can also cause a wide range of infections that…”
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Crossing Kingdoms: How the Mycobiota and Fungal-Bacterial Interactions Impact Host Health and Disease by Santus, William, Devlin, Jason R, Behnsen, Judith

“…The term "microbiota" invokes images of mucosal surfaces densely populated with bacteria. These surfaces and the luminal compartments they form indeed…”
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Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes virulence of plaque biofilms in vivo by Falsetta, Megan L, Klein, Marlise I, Colonne, Punsiri M, Scott-Anne, Kathleen, Gregoire, Stacy, Pai, Chia-Hua, Gonzalez-Begne, Mireya, Watson, Gene, Krysan, Damian J, Bowen, William H, Koo, Hyun

“…Streptococcus mutans is often cited as the main bacterial pathogen in dental caries, particularly in early-childhood caries (ECC). S. mutans may not act alone;…”
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Short-Chain Fatty Acids as a Potential Treatment for Infections: a Closer Look at the Lungs by Machado, Marina Gomes, Sencio, Valentin, Trottein, François

“…Short-chain fatty acids (SCFAs) are the main metabolites produced by the gut microbiota via the fermentation of complex carbohydrates and fibers. Evidence…”
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Roles of Eicosanoids in Regulating Inflammation and Neutrophil Migration as an Innate Host Response to Bacterial Infections by Sheppe, Austin E F, Edelmann, Mariola J

“…Eicosanoids are lipid-based signaling molecules that play a unique role in innate immune responses. The multiple types of eicosanoids, such as prostaglandins…”
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Synergistic interactions of Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro wound model by DeLeon, Stephanie, Clinton, Allie, Fowler, Haley, Everett, Jake, Horswill, Alexander R, Rumbaugh, Kendra P

“…In individuals with polymicrobial infections, microbes often display synergistic interactions that can enhance their colonization, virulence, or persistence…”
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Candidalysin Drives Epithelial Signaling, Neutrophil Recruitment, and Immunopathology at the Vaginal Mucosa by Richardson, Jonathan P, Willems, Hubertine M E, Moyes, David L, Shoaie, Saeed, Barker, Katherine S, Tan, Shir Lynn, Palmer, Glen E, Hube, Bernhard, Naglik, Julian R, Peters, Brian M

“…Unlike other forms of candidiasis, vulvovaginal candidiasis, caused primarily by the fungal pathogen , is a disease of immunocompetent and otherwise healthy…”
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Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease by Rynda-Apple, Agnieszka, Robinson, Keven M, Alcorn, John F

“…Seasonal influenza virus infection presents a major strain on the health care system. Influenza virus infection has pandemic potential, which was repeatedly…”
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Outer Membrane Lipid Secretion and the Innate Immune Response to Gram-Negative Bacteria by Giordano, Nicole P, Cian, Melina B, Dalebroux, Zachary D

“…The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet…”
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Microbial Composition Predicts Genital Tract Inflammation and Persistent Bacterial Vaginosis in South African Adolescent Females by Lennard, Katie, Dabee, Smritee, Barnabas, Shaun L, Havyarimana, Enock, Blakney, Anna, Jaumdally, Shameem Z, Botha, Gerrit, Mkhize, Nonhlanhla N, Bekker, Linda-Gail, Lewis, David A, Gray, Glenda, Mulder, Nicola, Passmore, Jo-Ann S, Jaspan, Heather B

“…Young African females are at an increased risk of HIV acquisition, and genital inflammation or the vaginal microbiome may contribute to this risk. We studied…”
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Iron Acquisition Mechanisms and Their Role in the Virulence of Acinetobacter baumannii by Cook-Libin, Shoshana, Sykes, Ellen M E, Kornelsen, Vanessa, Kumar, Ayush

“…Iron is an essential element for survival of most organisms. One mechanism of host defense is to tightly chelate iron to several proteins to limit its…”
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Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age by Barrila, Jennifer, Crabbé, Aurélie, Yang, Jiseon, Franco, Karla, Nydam, Seth D, Forsyth, Rebecca J, Davis, Richard R, Gangaraju, Sandhya, Ott, C Mark, Coyne, Carolyn B, Bissell, Mina J, Nickerson, Cheryl A

“…Tissues and organs provide the structural and biochemical landscapes upon which microbial pathogens and commensals function to regulate health and disease…”
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Aerobactin, but not yersiniabactin, salmochelin, or enterobactin, enables the growth/survival of hypervirulent (hypermucoviscous) Klebsiella pneumoniae ex vivo and in vivo by Russo, Thomas A, Olson, Ruth, MacDonald, Ulrike, Beanan, Janet, Davidson, Bruce A

“…The siderophore aerobactin is the dominant siderophore produced by hypervirulent Klebsiella pneumoniae (hvKP) and was previously shown to be a major virulence…”
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Influenza Virus Infection Impairs the Gut's Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids by Sencio, Valentin, Gallerand, Alexandre, Gomes Machado, Marina, Deruyter, Lucie, Heumel, Séverine, Soulard, Daphnée, Barthelemy, Johanna, Cuinat, Céline, Vieira, Angelica T, Barthelemy, Adeline, Tavares, Luciana P, Guinamard, Rodolphe, Ivanov, Stoyan, Grangette, Corinne, Teixeira, Mauro M, Foligné, Benoit, Wolowczuk, Isabelle, Le Goffic, Ronan, Thomas, Muriel, Trottein, François

“…Along with respiratory tract disease , viral respiratory infections can also cause extrapulmonary complications with a potentially critical impact on health…”
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Expanding Role of Type II Secretion in Bacterial Pathogenesis and Beyond by Cianciotto, Nicholas P, White, Richard C

“…Type II secretion (T2S) is one means by which Gram-negative pathogens secrete proteins into the extracellular milieu and/or host organisms. Based upon recent…”
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