Suchergebnisse - "Hundsberger, Thomas"

First Single-Centre Experience with the Novel HIF-α Inhibitor Belzutifan in Switzerland von Peres, Tobias, Aeppli, Stefanie, Fischer, Stefanie, Hundsberger, Thomas, Rothermundt, Christian

“… Belzutifan is a new HIF-α inhibitor mainly used in two different indications: von Hippel–Lindau syndrome-associated renal cell carcinoma, haemangioblastomas …”
Volltext

A phase Ib/II randomized, open-label drug repurposing trial of glutamate signaling inhibitors in combination with chemoradiotherapy in patients with newly diagnosed glioblastoma: the GLUGLIO trial protocol von Mastall, Maximilian, Roth, Patrick, Bink, Andrea, Fischer Maranta, Angela, Läubli, Heinz, Hottinger, Andreas Felix, Hundsberger, Thomas, Migliorini, Denis, Ochsenbein, Adrian, Seystahl, Katharina, Imbach, Lukas, Hortobagyi, Tibor, Held, Leonhard, Weller, Michael, Wirsching, Hans-Georg

“… Background Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large …”
Volltext

High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial von Thiel, Eckhard, Korfel, Agnieszka, Martus, Peter, Kanz, Lothar, Griesinger, Frank, Rauch, Michael, Röth, Alexander, Hertenstein, Bernd, von Toll, Theda, Hundsberger, Thomas, Mergenthaler, Hans-Günther, Leithäuser, Malte, Birnbaum, Tobias, Fischer, Lars, Jahnke, Kristoph, Herrlinger, Ulrich, Plasswilm, Ludwig, Nägele, Thomas, Pietsch, Torsten, Bamberg, Michael, Weller, Michael

“… High-dose methotrexate is the standard of care for patients with newly diagnosed primary CNS lymphoma. The role of whole brain radiotherapy is controversial …”
Volltext

Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma von Korfel, Agnieszka, Thiel, Eckhard, Martus, Peter, Möhle, Robert, Griesinger, Frank, Rauch, Michael, Röth, Alexander, Hertenstein, Bernd, Fischer, Thomas, Hundsberger, Thomas, Mergenthaler, Hans G, Junghanß, Christian, Birnbaum, Tobias, Fischer, Lars, Jahnke, Kristoph, Herrlinger, Ulrich, Roth, Patrick, Bamberg, Michael, Pietsch, Torsten, Weller, Michael

“… This is the final report of a phase III randomized study to evaluate whole-brain radiotherapy (WBRT) in primary therapy of primary CNS lymphoma (PCNSL) after a …”
Weitere Angaben

Comparison of recent pivotal recommendations for the diagnosis and treatment of late-onset Pompe disease using diagnostic nodes—the Pompe disease burden scale von Hundsberger, Thomas, Schoser, Benedikt, Leupold, Daniela, Rösler, Kai Michael, Putora, Paul Martin

“… Pompe disease is a rare autosomal-recessive disorder characterised by limb-girdle myopathy and respiratory weakness in the late-onset form (LOPD). Various …”
Volltext

Postoperative radiotherapy for meningiomas – a decision-making analysis von Fischer, Galina Farina, Brügge, Detlef, Andratschke, Nicolaus, Baumert, Brigitta Gertrud, Bosetti, Davide Giovanni, Caparrotti, Francesca, Herrmann, Evelyn, Papachristofilou, Alexandros, Rogers, Susanne, Schwyzer, Lucia, Zwahlen, Daniel Rudolf, Hundsberger, Thomas, Putora, Paul Martin

“… Background The management of meningiomas is challenging, and the role of postoperative radiotherapy is not standardized. Methods Radiation oncology experts in …”
Volltext

A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults von Roth, Patrick, Hottinger, Andreas F., Hundsberger, Thomas, Läubli, Heinz, Schucht, Philippe, Reinert, Michael, Mamot, Christoph, Roelcke, Ulrich, Pesce, Gianfranco, Hofer, Silvia, Weller, Michael

“… Gliomas are intrinsic brain tumours, which are classified by the World Health Organization (WHO) into different grades of malignancy, with glioblastoma being …”
Volltext

Laser Interstitial Thermal Therapy for Radionecrosis von Terrapon, Alexis Paul Romain, Krüger, Marie, Hundsberger, Thomas, Neidert, Marian Christoph, Bozinov, Oliver

“… Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic …”
Weitere Angaben

Applied Swarm-based medicine: collecting decision trees for patterns of algorithms analysis von Panje, Cédric M., Glatzer, Markus, von Rappard, Joscha, Rothermundt, Christian, Hundsberger, Thomas, Zumstein, Valentin, Plasswilm, Ludwig, Putora, Paul Martin

“… Background The objective consensus methodology has recently been applied in consensus finding in several studies on medical decision-making among clinical …”
Volltext

Real-world evidence for Pompe disease remains fragmented. Comment on “A rare partnership: patient community and industry collaboration to shape the impact of real-world evidence on the rare disease ecosystem” by Klein et al von Kruijshaar, Michelle E., House, Tiffany, Schoser, Benedikt, Laforêt, Pascal, Theunissen, Maudy T. M., Wenninger, Stephan, Hundsberger, Thomas, Diaz-Manera, Jordi, van der Ploeg, Ans T., van der Beek, Nadine A. M. E.

“… In a recent publication by Klein et al., the need for real-world data on rare diseases is highlighted. We strongly support this need, and the collaboration …”
Volltext

Correlation between age and the sciatic nerve diameter in the first 2 years of life: A high‐resolution ultrasound study von Jenny, Carole, Linde, Jacoba, Hundsberger, Thomas, Broser, Philip J.

“… Aim To investigate the maturation of the peripheral nervous system by analyzing the cross‐sectional area of the sciatic nerve during the first 2 years of life …”
Volltext

Natural ghrelin in advanced cancer patients with cachexia, a case series von Blum, David, Wolf‐Linder, Susanne, Oberholzer, Rolf, Brändle, Michael, Hundsberger, Thomas, Strasser, Florian

“… Background Natural ghrelin, a peptide growth hormone secretagogue, has a therapeutic potential in cachexia. We designed a dose‐finding trial of subcutaneous …”
Volltext

Temporal evolution of primary angiitis of the central nervous system (PACNS) on MRI following immunosuppressant treatment von Wagner, Franca, Almeida, Gonçalo G., Willems, Erik P., Weber, Johannes, Geiss, Johannes, Hundsberger, Thomas, Mordasini, Pasquale, Wildermuth, Simon, Leschka, Sebastian, Waelti, Stephan, Dietrich, Tobias Johannes, Fischer, Tim Steffen

“… Purpose To systematically analyse the time course of vessel wall enhancement and associated stenosis in patients with primary angiitis of the central nervous …”
Volltext

Impact of treatment decision algorithms on treatment costs in recurrent glioblastoma: a health economic study von Panje, Cédric M., Putora, Paul M., Hundsberger, Thomas, Hottinger, Andreas F., Roelcke, Ulrich, Pesce, Gianfranco, Herrmann, Evelyn, Matter-Walstra, Klazien

“… AIMS Recurrent glioblastoma (GBM) is a disease with poor prognosis. Although several therapeutic approaches such as chemotherapy, irradiation or surgery have …”
Volltext

Correlation of age and the diameter of the cervical nerve roots C5 and C6 during the first 2 years of life analyzed by high‐resolution ultrasound imaging von Linde, Jacoba, Jenny, Carole, Hundsberger, Thomas, Broser, Philip J.

“… Aim To analyze the increase in diameter of the nerve roots C5 and C6 in early childhood. Methods The nerve roots of 56 children aged 0 days to 10 years (47 …”
Volltext

Fitness-to-drive for glioblastoma patients von Silvia Hofer, Kristina Keller, Lukas Imbach, Ulrich Roelcke, Gregor Hutter, Thomas Hundsberger, Caroline Hertler, Emilie Le Rhun, Flavio Vasella, Dominik Cordier, Marian Neidert, Andreas Hottinger, Denis Migliorini, Tobias Pflugshaupt, Noemi Eggenberger, Brigitta Baumert, Heinz Läubli, Dorothee Gramatzki, Michael Reinert, Gianfranco Pesce, Philippe Schucht, Irene Frank, Dirk Lehnick, Tobias Weiss, Hans-Georg Wirsching, Fabian Wolpert, Patrick Roth, Michael Weller

“… OBJECTIVE The management of brain tumour patients who would like to resume driving is complex, and needs multidisciplinary input and a consensus among treating …”
Volltext

Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03 von Herrlinger, Ulrich, Rieger, Johannes, Koch, Dorothee, Loeser, Simon, Blaschke, Britta, Kortmann, Rolf-Dieter, Steinbach, Joachim P, Hundsberger, Thomas, Wick, Wolfgang, Meyermann, Richard, Tan, Ta-Chih, Sommer, Clemens, Bamberg, Michael, Reifenberger, Guido, Weller, Michael

“… To evaluate toxicity and efficacy of the combination of lomustine, temozolomide (TMZ) and involved-field radiotherapy in patients with newly diagnosed …”
Weitere Angaben

A phase 1/2a dose-finding study and biomarker assessment of oral lisavanbulin in patients with high-grade glioma or glioblastoma von Lopez, Juanita Suzanne, Haefliger, Simon, Plummer, Ruth, Clement, Paul M., Jeffry Evans, Thomas R., Läubli, Heinz, Roth, Patrick, Kristeleit, Rebecca, Brazil, Lucy, Tabatabai, Ghazaleh, Wick, Antje, Wunderlich, Benjamin, Beebe, Kirk, Eisner, Joel Robert, Lane, Heidi, Engelhardt, Marc, Kaindl, Thomas, Hau, Peter, Hundsberger, Thomas, Steinbach, Joachim

“… Lisavanbulin is a prodrug of the microtubule-targeting agent avanbulin. Both avanbulin and lisavanbulin have demonstrated significant antitumor activity in …”
Volltext

Fitness-to-drive for glioblastoma patients: Guidance from the Swiss Neuro-Oncology Society (SwissNOS) and the Swiss Society for Legal Medicine (SGRM) von Hofer, Silvia, Keller, Kristina, Imbach, Lukas, Roelcke, Ulrich, Hutter, Gregor, Hundsberger, Thomas, Hertler, Caroline, Le Rhun, Emilie, Vasella, Flavio, Cordier, Dominik, Neidert, Marian, Hottinger, Andreas, Migliorini, Denis, Pflugshaupt, Tobias, Eggenberger, Noemi, Baumert, Brigitta, Läubli, Heinz, Gramatzki, Dorothee, Reinert, Michael, Pesce, Gianfranco, Schucht, Philippe, Frank, Irene, Lehnick, Dirk, Weiss, Tobias, Wirsching, Hans-Georg, Wolpert, Fabian, Roth, Patrick, Weller, Michael

“… OBJECTIVE The management of brain tumour patients who would like to resume driving is complex, and needs multidisciplinary input and a consensus among treating …”
Volltext

Hot Topics on COVID-19 and Its Possible Association with Guillain-Barré Syndrome von Dietmann, Anelia, Ripellino, Paolo, Humm, Andrea M., Hundsberger, Thomas, Schreiner, Bettina, Théaudin, Marie, Scheidegger, Olivier

“… As the COVID-19 pandemic progresses, reports of neurological manifestations are increasing. However, despite a high number of case reports and case series on …”
Volltext