Suchergebnisse - "Hopf, N.B."

Urinary 8-isoprostane as a biomarker for oxidative stress. A systematic review and meta-analysis von Graille, M., Wild, P., Sauvain, J-J, Hemmendinger, M., Guseva Canu, I., Hopf, N.B.

“… •Population values for the oxidative stress biomarker, urinary 8-isoprostane.•Pooled GM values in healthy adults were 0.18 to 0.40 μg/g creatinine.•Chemical …”
Volltext

State of knowledge on the occupational exposure to carbon nanotubes von Guseva Canu, I., Batsungnoen, K., Maynard, A., Hopf, N.B.

“… Carbon nanotubes (CNT) trigger fascination as well as anxiety, given their unique physical and chemical properties, and continuing concerns around their …”
Volltext

Are metals in exhaled breath condensate and urine associated with oxidative/nitrosative stress and metabolism-related biomarkers? Results from 303 randomly selected Parisian subway workers von Sauvain, J.J., Wild, P., Charreau, T., Jouannique, V., Sakthithasan, K., Debatisse, A., Suárez, G., Hopf, N.B., Guseva Canu, I.

“… [Display omitted] •Metals associated with anions in exhaled breath condensate (EBC)•Urinary metals associated with oxidative stress biomarkers in subway …”
Volltext

LP-45 Application of a unified probabilistic framework to the dose-response assessment of selected nitrosamines and derivation of health-based exposure limits (HBELs) von Blum, K., FitzGerald, R., Wilks, M.F., Hopf, N.B.

Volltext

P03-02: The use of buccal micronucleus cytome assay as an additional biomarker in the assessment of exposure to air pollutants in colder and warmer periods in the chronically exposed Zagreb (Croatia) residents von Milić, M., Kašuba, V., Matković, K., Delić, L., Jakovljević, I., Davila, S., Pehnec, G., Guseva Canu, I., Hopf, N.B., Gerić, M., Gajski, G.

Volltext

P06-13: Machine learning in predicting genotoxicity biomarkers based on the exposure to air pollutants in colder and warmer periods in the general population of Zagreb (Croatia) von Matković, K., Delić, L., Jurič, A., Davila, S., Milić, M., Jakovljević, I., Kašuba, V., Pehnec, G., Hopf, N.B., Guseva Canu, I., Brčić Karačonji, I., Gajski, G., Gerić, M.

Volltext

P03-02: The use of buccal micronucleuscytomeassay as an additional biomarker in the assessment of exposure to air pollutants in colder and warmer periods in the chronically exposed Zagreb (Croatia) residents von Milić, M., Kašuba, V., Matković, K., Delić, L., Jakovljević, I., Davila, S., Pehnec, G., Guseva Canu, I., Hopf, N.B., Gerić, M., Gajski, G.

Volltext

Towards a systematic use of effect biomarkers in population and occupational biomonitoring von Zare Jeddi, Maryam, Hopf, Nancy B., Viegas, Susana, Price, Anna Bal, Paini, Alicia, van Thriel, Christoph, Benfenati, Emilio, Ndaw, Sophie, Bessems, Jos, Behnisch, Peter A., Leng, Gabriele, Duca, Radu-Corneliu, Verhagen, Hans, Cubadda, Francesco, Brennan, Lorraine, Ali, Imran, David, Arthur, Mustieles, Vicente, Fernandez, Mariana F., Louro, Henriqueta, Pasanen-Kase, Robert

“… •Reliable effect biomarkers are available for most of the relevant MoAs.•Increasing AOP knowledge fosters the use of effect biomarkers in regulatory …”
Volltext

Predicting human neurotoxicity of propylene glycol methyl ether (PGME) by implementing in vitro neurotoxicity results into toxicokinetic modelling von Reale, E., Sandstrom, J., Culot, M., Hechon, J., Wellens, S., Heymans, M., Tschudi-Monnet, F., Vernez, D., Hopf, N.B.

“… Although organic solvents have been associated with CNS toxicity, neurotoxicity testing is rarely a regulatory requirement. We propose a strategy to assess the …”
Volltext

LP-15 Decoding the Urban Exposome: Integrative Statistical Modelling of Epigenetic, Oxidative, and Genotoxic Biomarkers in Response to Air Pollution von Matković, K., Jakovljević, I., Davila, S., Milić, M., Kašuba, V., Pehnec, G., Kazensky, L., Domijan, A.-M., Bočkor, V. Vičić, Lukšić, F., Zoldoš, V., Cvetković, Ž., Knežević, M. Šentija, Stjepanović, B., Bošnir, J., Hopf, N.B., Canu, I. Guseva, Wild, P., Gajski, G., Gerić, M.

“… Urban air pollution, even at moderate levels, can induce early biological changes relevant to respiratory and systemic health. This study investigated the …”
Volltext

P21-08: Building a strategy to assess the neurotoxicity of glycol ethers von Pamies, D., Werner, S., Puligilla, R. Deepthi, Paschoud, H., Hegg, L., Reale, E., Borgatta, M., Bertoli, J., Repond, C., Meister, I., Sajic, T., Boccard, J., Rudaz, S., Thomas, A., Huwyler, J., Hopf, N.B., Suter-Dick, L., Zurich, M.-G.

Volltext

Skin permeation and metabolism of di(2-ethylhexyl) phthalate (DEHP) von Hopf, N.B., Berthet, A., Vernez, D., Langard, E., Spring, P., Gaudin, R.

“… •DEHP is extensively metabolized in vitro in human viable skin.•DEHP pass readily through human skin when emulsified in aqueous solution.•Percutaneous …”
Volltext

Reflections on the OECD guidelines for in vitro skin absorption studies von Hopf, N.B., Champmartin, C., Schenk, L., Berthet, A., Chedik, L., Du Plessis, J.L., Franken, A., Frasch, F., Gaskin, S., Johanson, G., Julander, A., Kasting, G., Kilo, S., Larese Filon, F., Marquet, F., Midander, K., Reale, E., Bunge, A.L.

“… At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals (OEESC) (16–18 September 2019) in Dublin, Ireland, several …”
Volltext

Particle and metal exposure in Parisian subway: Relationship between exposure biomarkers in air, exhaled breath condensate, and urine von Guseva Canu, I., Crézé, C., Hemmendinger, M., Ben Rayana, T., Besançon, S., Jouannique, V., Debatisse, A., Wild, P., Sauvain, J.J., Suárez, G., Hopf, N.B.

“… Subway particulate toxicity results from in vitro and in vivo studies diverge and call for applied human research on outcomes from chronic exposures and …”
Volltext

Influence of experimental parameters on in vitro human skin permeation of Bisphenol A von Reale, E., Berthet, A., Wild, P., Vernez, D., Hopf, N.B.

“… Bisphenol A (BPA) in vitro skin permeation studies have shown inconsistent results, which could be due to experimental conditions. We studied the impact of in …”
Volltext

Ethics in managing occupational biomonitoring programs von Berthet, A., Pralong, L., Benaroyo, L., Vernez, D., Hopf, N.B.

Volltext

Respiratory Disease Occupational Biomonitoring Collaborative Project (ROBoCoP): A longitudinal pilot study and implementation research in the Parisian transport company von Guseva Canu, I., Hemmendinger, M., Sauvain, J. J., Suarez, G., Hopf, N. B., Pralong, J. A., Ben Rayana, T., Besançon, S., Sakthithasan, K., Jouannique, V., Debatisse, A.

“… The ROBoCoP project is launched within the EU COST Action CA16113 “CliniMARK” aiming to increase the number of clinically validated biomarkers and focused on …”
Volltext

A new alternative method for testing skin irritation using a human skin model: A pilot study von Miles, A., Berthet, A., Hopf, N.B., Gilliet, M., Raffoul, W., Vernez, D., Spring, P.

“… •This new in vitro allows us to assess in a valuable way skin irritation.•Although using fresh skin, we had no false positive and no false negative …”
Volltext