Suchergebnisse - "Hollway, Georgina E"

miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense von Pajic, Marina, Froio, Danielle, Daly, Sheridan, Doculara, Louise, Millar, Ewan, Graham, Peter H, Drury, Alison, Steinmann, Angela, de Bock, Charles E, Boulghourjian, Alice, Zaratzian, Anaiis, Carroll, Susan, Toohey, Joanne, O'Toole, Sandra A, Harris, Adrian L, Buffa, Francesca M, Gee, Harriet E, Hollway, Georgina E, Molloy, Timothy J

“… Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem …”
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Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency von Yap, Jin Yan, Moens, Leen, Lin, Ming-Wei, Kane, Alisa, Kelleher, Anthony, Toong, Catherine, Wu, Kathy H.C., Sewell, William A., Phan, Tri Giang, Hollway, Georgina E., Enthoven, Karen, Gray, Paul E., Casas-Martin, Jose, Wouters, Carine, De Somer, Lien, Hershfield, Michael, Bucciol, Giorgia, Delafontaine, Selket, Ma, Cindy S., Tangye, Stuart G., Meyts, Isabelle

“… Purpose Deficiency of adenosine deaminase type 2 (ADA2) (DADA2) is a rare inborn error of immunity caused by deleterious biallelic mutations in ADA2 . Clinical …”
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The clinical utility and costs of whole-genome sequencing to detect cancer susceptibility variants—a multi-site prospective cohort study von Davidson, Aimee L., Dressel, Uwe, Norris, Sarah, Canson, Daffodil M., Glubb, Dylan M., Fortuno, Cristina, Hollway, Georgina E., Parsons, Michael T., Vidgen, Miranda E., Holmes, Oliver, Koufariotis, Lambros T., Lakis, Vanessa, Leonard, Conrad, Wood, Scott, Xu, Qinying, McCart Reed, Amy E., Pickett, Hilda A., Al-Shinnag, Mohammad K., Austin, Rachel L., Burke, Jo, Cops, Elisa J., Nichols, Cassandra B., Goodwin, Annabel, Harris, Marion T., Higgins, Megan J., Ip, Emilia L., Kiraly-Borri, Catherine, Lau, Chiyan, Mansour, Julia L., Millward, Michael W., Monnik, Melissa J., Pachter, Nicholas S., Ragunathan, Abiramy, Susman, Rachel D., Townshend, Sharron L., Trainer, Alison H., Troth, Simon L., Tucker, Katherine M., Wallis, Mathew J., Walsh, Maie, Williams, Rachel A., Winship, Ingrid M., Newell, Felicity, Tudini, Emma, Pearson, John V., Poplawski, Nicola K., Mar Fan, Helen G., James, Paul A., Spurdle, Amanda B., Waddell, Nicola, Ward, Robyn L.

“… Background Many families and individuals do not meet criteria for a known hereditary cancer syndrome but display unusual clusters of cancers. These families …”
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Whole-somite rotation generates muscle progenitor cell compartments in the developing zebrafish embryo von Hollway, Georgina E, Bryson-Richardson, Robert J, Berger, Silke, Cole, Nicholas J, Hall, Thomas E, Currie, Peter D

“… Somites are transient, mesodermally derived structures that give rise to a number of different cell types within the vertebrate embryo. To achieve this, …”
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Scube activity is necessary for Hedgehog signal transduction in vivo von Johnson, Jacque-Lynne F.A., Hall, Thomas E., Dyson, Jennifer M., Sonntag, Carmen, Ayers, Katie, Berger, Silke, Gautier, Philippe, Mitchell, Christina, Hollway, Georgina E., Currie, Peter D.

“… The Hedgehog (HH) signaling pathway is a central regulator of embryonic development, controlling the pattern and proliferation of a wide variety of organs …”
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Stac3 is required for myotube formation and myogenic differentiation in vertebrate skeletal muscle von Bower, Neil I, de la Serrana, Daniel Garcia, Cole, Nicholas J, Hollway, Georgina E, Lee, Hung-Tai, Assinder, Stephen, Johnston, Ian A

“… Stac3 was identified as a nutritionally regulated gene from an Atlantic salmon subtractive hybridization library with highest expression in skeletal muscle …”
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Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants von Svetic, Valentina, Hollway, Georgina E, Elworthy, Stone, Chipperfield, Thomas R, Davison, Claire, Adams, Richard J, Eisen, Judith S, Ingham, Philip W, Currie, Peter D, Kelsh, Robert N

“… Pigment pattern formation in zebrafish presents a tractable model system for studying the morphogenesis of neural crest derivatives. Embryos mutant for choker …”
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Analysis of hereditary cancer gene variant classifications from ClinVar indicates a need for regular reassessment of clinical assertions von Davidson, Aimee L., Kondrashova, Olga, Leonard, Conrad, Wood, Scott, Tudini, Emma, Hollway, Georgina E., Pearson, John V., Newell, Felicity, Spurdle, Amanda B., Waddell, Nicola

“… The clinical classification of variants may change with new information, however, there is limited guidance on how often significant changes in variant …”
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Met and Hgf signaling controls hypaxial muscle and lateral line development in the zebrafish von Haines, Lynn, Neyt, Christine, Gautier, Philippe, Keenan, David G, Bryson-Richardson, Robert J, Hollway, Georgina E, Cole, Nicolas J, Currie, Peter D

“… Somites give rise to a number of different embryonic cell types, including the precursors of skeletal muscle populations. The lateral aspect of amniote and …”
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Considerations for using population frequency data in germline variant interpretation: Cancer syndrome genes as a model von Davidson, Aimee L., Leonard, Conrad, Koufariotis, Lambros T., Parsons, Michael T., Hollway, Georgina E., Pearson, John V., Newell, Felicity, Waddell, Nicola, Spurdle, Amanda B.

“… Aggregate population genomics data from large cohorts are vital for assessing germline variant pathogenicity. However, there are no specifications on how …”
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Scube2 mediates Hedgehog signalling in the zebrafish embryo von Hollway, Georgina E., Maule, John, Gautier, Philippe, Evans, Timothy M., Keenan, David G., Lohs, Claudia, Fischer, Danielle, Wicking, Carol, Currie, Peter D.

“… The Hedgehog family of secreted morphogens specifies the fate of a large number of different cell types within invertebrate and vertebrate embryos, including …”
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Cadherin-mediated differential cell adhesion controls slow muscle cell migration in the developing zebrafish myotome von Cortés, Fernando, Daggett, David, Bryson-Richardson, Robert J, Neyt, Christine, Maule, John, Gautier, Phillipe, Hollway, Georgina E, Keenan, David, Currie, Peter D

“… Slow-twitch muscle fibers of the zebrafish myotome undergo a unique set of morphogenetic cell movements. During embryogenesis, slow-twitch muscle derives from …”
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Myotome meanderings: Cellular morphogenesis and the making of muscle von Hollway, Georgina E, Currie, Peter D

“… The formation of muscles within the vertebrate embryo is a tightly orchestrated and complex undertaking. Beyond the initial specification of cells to become …”
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Myotome meanderings von Hollway, Georgina E, Currie, Peter D

“… The formation of muscles within the vertebrate embryo is a tightly orchestrated and complex undertaking. Beyond the initial specification of cells to become …”
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Deafness due to Pro250Arg mutation of FGFR3 von Hollway, Georgina E, Suthers, Graeme K, Battese, Katie M, Turner, Anne M, David, David J, Mulley, John C

“… Hollway et al identified a family with autosomal dominant craniosynostosis and bilateral sensorineural hearing loss. They suggest that people with autosomal …”
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Polymorphic variants within the homeobox gene MSX1: a candidate gene for developmental disorders von Hollway, Georgina E, Mulley, John C

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The zebrafish candyfloss mutant implicates extracellular matrix adhesion failure in laminin alpha2-deficient congenital muscular dystrophy von Hall, Thomas E, Bryson-Richardson, Robert J, Berger, Silke, Jacoby, Arie S, Cole, Nicholas J, Hollway, Georgina E, Berger, Joachim, Currie, Peter D

“… Mutations in the human laminin alpha2 (LAMA2) gene result in the most common form of congenital muscular dystrophy (MDC1A). There are currently three models …”
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Zebrafish earn their stripes von Hollway, Georgina E, Currie, Peter D

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Zebrafish earn their stripes: The Zebrafish: Biology and The Zebrafish: Genetics and Genomics, Methods in Cell Biology Volumes 59 and 60 Edited by H.W. Detrich III, M. Westerfield and L.I. Zon von Hollway, Georgina E, Currie, Peter D

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Mutation detection in FGFR2 craniosynostosis syndromes von Hollway, G. E., Suthers, Graeme K., Haan, Eric A., Thompson, Elizabeth, David, David J., Gecz, Jozef, Mulley, John C.

“… Five autosomal dominant craniosynostosis syndromes (Apert, Crouzon, Pfeiffer, Jackson-Weiss and Crouzon syndrome with acanthosis nigricans) result from …”
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