Suchergebnisse - "Hematologic Neoplasms - pathology"

Clonal dynamics of haematopoiesis across the human lifespan von Mitchell, Emily, Spencer Chapman, Michael, Williams, Nicholas, Dawson, Kevin J., Mende, Nicole, Calderbank, Emily F., Jung, Hyunchul, Mitchell, Thomas, Coorens, Tim H. H., Spencer, David H., Machado, Heather, Lee-Six, Henry, Davies, Megan, Hayler, Daniel, Fabre, Margarete A., Mahbubani, Krishnaa, Abascal, Federico, Cagan, Alex, Vassiliou, George S., Baxter, Joanna, Martincorena, Inigo, Stratton, Michael R., Kent, David G., Chatterjee, Krishna, Parsy, Kourosh Saeb, Green, Anthony R., Nangalia, Jyoti, Laurenti, Elisa, Campbell, Peter J.

“… Here we sequenced 3,579 genomes from single cell-derived colonies of haematopoietic cells across 10 human subjects from 0 to 81 years of age …”
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Splicing factor mutations in hematologic malignancies von Chen, Sisi, Benbarche, Salima, Abdel-Wahab, Omar

“… neoplasms and several types of lymphoproliferative disorders, as well as subjects with clonal hematopoiesis …”
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Clonal hematopoiesis as a model for premalignant changes during aging von Steensma, David P., Ebert, Benjamin L.

“… •Imbalanced hematopoiesis in which one clone or a small group of clones bearing somatic mutations contribute an outsized proportion of blood cell production, …”
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Role of artificial intelligence in haematolymphoid diagnostics von Syrykh, Charlotte, Brand, Michiel, Kather, Jakob Nikolas, Laurent, Camille

“… From diagnostic assistance to powerful research tools, the potential fields of application of machine learning techniques in pathology are vast and constitute the subject of considerable research work …”
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High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders von Caivano, Antonella, Laurenzana, Ilaria, De Luca, Luciana, La Rocca, Francesco, Simeon, Vittorio, Trino, Stefania, D’Auria, Fiorella, Traficante, Antonio, Maietti, Maddalena, Izzo, Tiziana, D’Arena, Giovanni, Mansueto, Giovanna, Pietrantuono, Giuseppe, Laurenti, Luca, Musto, Pellegrino, Del Vecchio, Luigi

“… ) remain largely unexplored. The aim of this study was to characterize EVs in peripheral blood of HM patients compared to healthy subjects (controls …”
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FOXP1 is associated with oncogenesis and clinical outcomes in hematologic malignancies von Wen, Xiang-mei, Xu, Zi-jun, Ni, Hao-xi, Liu, Su-wan, Jin, Ye, Zhao, Wei, Luo, Shu-yu, Fang, Yuan-yuan, Mao, Zhen-wei, Lin, Jiang, Qian, Jun

“… FOXP1 was highly expressed in acute myeloid leukemia (AML). Methylation of the FOXP1 promoter was significantly reduced in patients with AML compared to the healthy control subjects and those with …”
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Clonal Megakaryocyte Dysplasia with Normal Blood Values Is a Distinct Myeloproliferative Neoplasm von Barosi, Giovanni, Rosti, Vittorio, Massa, Margherita, Campanelli, Rita, Villani, Laura, Catarsi, Paolo, Carolei, Adriana, Abbà, Carlotta, Lodigiani, Corrado, Primignani, Massimo, Gregato, Giuliana, Bertolini, Francesco, Magrini, Umberto, Gale, Robert Peter

“… We sought to gain further knowledge on this disease entity. This retrospective cohort study included consecutive subjects registered in the database of the Center for the Study of Myelofibrosis in Pavia, Italy, from 1998 to 2020 (June …”
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Pemphigus and hematologic malignancies: A population-based study of 11,859 patients von Kridin, Khalaf, Zelber-Sagi, Shira, Comaneshter, Doron, Batat, Erez, Cohen, Arnon D.

“… A cross-sectional study was conducted comparing pemphigus patients with age-, sex- and ethnicity-matched control subjects regarding the prevalence of 6 comorbid hematologic malignancies …”
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The bone marrow microenvironment is similarly impaired in allogeneic hematopoietic stem cell transplantation patients with early and late poor graft function von Kong, Y, Wang, Y-T, Hu, Y, Han, W, Chang, Y-J, Zhang, X-H, Jiang, Z-F, Huang, X-J

“… –control study comparing cellular elements of the bone marrow microenvironment in 10 subjects with early PGF, 30 subjects with late PGF and 40 subjects without PGF …”
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Overlapping SETBP1 gain-of-function mutations in Schinzel-Giedion syndrome and hematologic malignancies von Acuna-Hidalgo, Rocio, Deriziotis, Pelagia, Steehouwer, Marloes, Gilissen, Christian, Graham, Sarah A., van Dam, Sipko, Hoover-Fong, Julie, Telegrafi, Aida B., Destree, Anne, Smigiel, Robert, Lambie, Lindsday A., Kayserili, Hülya, Altunoglu, Umut, Lapi, Elisabetta, Uzielli, Maria Luisa, Aracena, Mariana, Nur, Banu G., Mihci, Ercan, Moreira, Lilia M. A., Borges Ferreira, Viviane, Horovitz, Dafne D. G., da Rocha, Katia M., Jezela-Stanek, Aleksandra, Brooks, Alice S., Reutter, Heiko, Cohen, Julie S., Fatemi, Ali, Smitka, Martin, Grebe, Theresa A., Di Donato, Nataliya, Deshpande, Charu, Vandersteen, Anthony, Marques Lourenço, Charles, Dufke, Andreas, Rossier, Eva, Andre, Gwenaelle, Baumer, Alessandra, Spencer, Careni, McGaughran, Julie, Franke, Lude, Veltman, Joris A., De Vries, Bert B. A., Schinzel, Albert, Fisher, Simon E., Hoischen, Alexander, van Bon, Bregje W.

“… Schinzel-Giedion syndrome (SGS) is a rare developmental disorder characterized by multiple malformations, severe neurological alterations and increased risk of …”
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Relation between mutations in the 5′ UTR of ANKRD26 gene and inherited thrombocytopenia with predisposition to myeloid malignancies. An Egyptian study von Zidan, Nahla Ibrahim, AbdElmonem, Doaa Metwally, Elsheikh, Haitham Mohamed, Metwally, Elsayed Anany, Mokhtar, Wesam AbdElmonem, Osman, Gamal Mohamed

“… Inherited thrombocytopenias are a heterogeneous group of diseases characterized by a reduced number of platelets and a bleeding tendency that ranges from very …”
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Wnt Signaling in Hematological Malignancies von Grainger, Stephanie, Traver, David, Willert, Karl

“… that is known to be Wnt-responsive. In particular, the progenitor populations are subject to uncontrolled expansion during oncogenic processes, namely the common myeloid …”
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The clinical and financial burden of pre-emptive management of cytomegalovirus disease after allogeneic stem cell transplantation—implications for preventative treatment approaches von Jain, Natasha A., Lu, Kit, Ito, Sawa, Muranski, Pawel, Hourigan, Christopher S., Haggerty, Janice, Chokshi, Puja D., Ramos, Catalina, Cho, Elena, Cook, Lisa, Childs, Richard, Battiwalla, Minoo, Barrett, A. John

“… Eighty-one subjects received CD34+ selected myeloablative SCT, 12 umbilical cord blood transplants, and 41 T-replete non-myeloablative SCT …”
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Association of mast cells and bone marrow reticulin fibrosis in patients with bcr-abl negative chronic myeloproliferative neoplasms von Keski, Hakan

“… Thirty patients with lymphoma served as controls. JAK2 mutation was studied and all subjects underwent bone marrow biopsy at the time of diagnosis. Mast and CD34+ cells were counted …”
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Autotaxin and soluble IL-2 receptor concentrations in cerebrospinal fluids are useful for the diagnosis of central nervous system invasion caused by haematological malignancies von Shimura, Takuya, Kurano, Makoto, Morita, Yoshifumi, Yoshikawa, Naoyuki, Nishikawa, Masako, Igarashi, Koji, Shimamoto, Satoshi, Aoki, Junken, Yatomi, Yutaka

“… We observed that both the autotaxin and soluble IL-2 receptor concentrations in cerebrospinal fluid were higher in subjects with central nervous system invasion than in those …”
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Quality control initiative on the evaluation of the dysmegakaryopoiesis in myeloid neoplasms: Difficulties in the assessment of dysplasia von Goasguen, Jean E., Bennett, John M., Bain, Barbara J., Brunning, Richard D., Vallespí, Maria-Teresa, Tomonaga, Masao, Zini, Gina, Renault, Alain

“… •The presence of micromegakaryocytes correlates strongly with myeloid neoplasia.•Micromegakaryocytes can be identified reliably.•Multinucleated megakaryocytes …”
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Genetic predisposition and hematopoietic malignancies in children: Primary immunodeficiency von van der Werff ten Bosch, Jutte, van den Akker, Machiel

“… It is assumed that patients with some forms of primary immunodeficiency (PID) have a markedly increased risk of cancer as compared to the healthy population …”
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Childhood cancer in Gondar University Hospital, Northwest Ethiopia von Yifru, Sisay, Muluye, Dagnachew

“… Background Childhood cancer becomes a public health problem in developing countries which aggravates the burden of childhood mortality by infectious diseases …”
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Cardiac output response to exercise in patients before allogenic hematopoietic stem cell transplantation von Yoshida, Shinya, Someya, Fujiko, Yahata, Tetsutaro

“… Introduction High-dose chemotherapy for remission induction can induce cardiac toxicity prior to hematopoietic stem cell transplantation (HSCT). However, the …”
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Molecular analysis of more than 140 gene fusion variants and aberrant activation of EVI1 and TLX1 in hematological malignancies von Ghasemian Sorbeni, Faramarz, Montazersaheb, Soheila, Ansarin, Atefeh, Esfahani, Ali, Rezamand, Azim, Sakhinia, Ebrahim

“… Gene fusions are observed in abnormal chromosomal rearrangements such as translocations in hematopoietic malignancies, especially leukemia subtypes. Hence, it …”
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