Výsledky vyhľadávania - "Heckbert, Susan R."

Incidence of and risk factors for sick sinus syndrome in the general population Autor Jensen, Paul N, Gronroos, Noelle N, Chen, Lin Y, Folsom, Aaron R, deFilippi, Chris, Heckbert, Susan R, Alonso, Alvaro

“…Little is known about the incidence of and risk factors for sick sinus syndrome (SSS), a common indication for pacemaker implantation. This study sought to…”
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Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism Autor Lindström, Sara, Wang, Lu, Smith, Erin N, Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A, Pattee, Jack W, Haessler, Jeffrey, Brumpton, Ben M, Chasman, Daniel I, Suchon, Pierre, Chen, Ming-Huei, Turman, Constance, Germain, Marine, Wiggins, Kerri L, MacDonald, James, Braekkan, Sigrid K, Armasu, Sebastian M, Pankratz, Nathan, Jackson, Rebecca D, Nielsen, Jonas B, Giulianini, Franco, Puurunen, Marja K, Ibrahim, Manal, Heckbert, Susan R, Damrauer, Scott M, Natarajan, Pradeep, Klarin, Derek, de Vries, Paul S, Sabater-Lleal, Maria, Huffman, Jennifer E, Bammler, Theo K, Frazer, Kelly A, McCauley, Bryan M, Taylor, Kent, Pankow, James S, Reiner, Alexander P, Gabrielsen, Maiken E, Deleuze, Jean-François, O'Donnell, Chris J, Kim, Jihye, McKnight, Barbara, Kraft, Peter, Hansen, John-Bjarne, Rosendaal, Frits R, Heit, John A, Psaty, Bruce M, Tang, Weihong, Kooperberg, Charles, Hveem, Kristian, Ridker, Paul M, Morange, Pierre-Emmanuel, Johnson, Andrew D, Kabrhel, Christopher, Trégouët, David-Alexandre, Smith, Nicholas L

“…Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To advance our understanding of the biology contributing to VTE, we…”
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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation Autor Choi, Seung Hoan, Weng, Lu-Chen, Roselli, Carolina, Lin, Honghuang, Haggerty, Christopher M, Shoemaker, M Benjamin, Barnard, John, Arking, Dan E, Chasman, Daniel I, Albert, Christine M, Chaffin, Mark, Tucker, Nathan R, Smith, Jonathan D, Gupta, Namrata, Gabriel, Stacey, Margolin, Lauren, Shea, Marisa A, Shaffer, Christian M, Yoneda, Zachary T, Boerwinkle, Eric, Smith, Nicholas L, Silverman, Edwin K, Redline, Susan, Vasan, Ramachandran S, Burchard, Esteban G, Gogarten, Stephanie M, Laurie, Cecelia, Blackwell, Thomas W, Abecasis, Gonçalo, Carey, David J, Fornwalt, Brandon K, Smelser, Diane T, Baras, Aris, Dewey, Frederick E, Jaquish, Cashell E, Papanicolaou, George J, Sotoodehnia, Nona, Van Wagoner, David R, Psaty, Bruce M, Kathiresan, Sekar, Darbar, Dawood, Alonso, Alvaro, Heckbert, Susan R, Chung, Mina K, Roden, Dan M, Benjamin, Emelia J, Murray, Michael F, Lunetta, Kathryn L, Lubitz, Steven A, Ellinor, Patrick T

“…Atrial fibrillation (AF) is the most common arrhythmia affecting 1% of the population. Young individuals with AF have a strong genetic association with the…”
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Ventricular Ectopy as a Predictor of Heart Failure and Death Autor Dukes, Jonathan W, Dewland, Thomas A, Vittinghoff, Eric, Mandyam, Mala C, Heckbert, Susan R, Siscovick, David S, Stein, Phyllis K, Psaty, Bruce M, Sotoodehnia, Nona, Gottdiener, John S, Marcus, Gregory M

“…Studies of patients presenting for catheter ablation suggest that premature ventricular contractions (PVCs) are a modifiable risk factor for congestive heart…”
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P-wave morphology and the risk of incident ischemic stroke in the Multi-Ethnic Study of Atherosclerosis Autor Kamel, Hooman, Soliman, Elsayed Z, Heckbert, Susan R, Kronmal, Richard A, Longstreth, Jr, W T, Nazarian, Saman, Okin, Peter M

“…Emerging data suggest that left atrial disease may cause ischemic stroke in the absence of atrial fibrillation or flutter (AF). If true, this condition may…”
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Atrial Cardiopathy and the Risk of Ischemic Stroke in the CHS (Cardiovascular Health Study) Autor Kamel, Hooman, Bartz, Traci M, Elkind, Mitchell S V, Okin, Peter M, Thacker, Evan L, Patton, Kristen K, Stein, Phyllis K, deFilippi, Christopher R, Gottesman, Rebecca F, Heckbert, Susan R, Kronmal, Richard A, Soliman, Elsayed Z, Longstreth, Jr, W T

“…Emerging evidence suggests that an underlying atrial cardiopathy may result in thromboembolism before atrial fibrillation (AF) develops. We examined the…”
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Mapping the relationships between structural brain MRI characteristics and sleep electroencephalography patterns: the Multi-Ethnic Study of atherosclerosis Autor Kozhemiako, Nataliia, Heckbert, Susan R, Castro-Diehl, Cecilia, Paquet, Caitlin B, Bertisch, Suzanne M, Habes, Mohamad, Fohner, Alison E, Bryan, Robert Nick, Nasrallah, Ilya, Hughes, Timothy M, Redline, Susan, Purcell, Shaun M

“…While brain morphology is well-established as a key factor influencing overall brain function, little is known about how brain structural properties are…”
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Lifetime Risk of Venous Thromboembolism in Two Cohort Studies Autor Bell, Elizabeth J, Lutsey, Pamela L, Basu, Saonli, Cushman, Mary, Heckbert, Susan R, Lloyd-Jones, Donald M, Folsom, Aaron R

“…Greater public awareness of venous thromboembolism may be an important next step for optimizing venous thromboembolism prevention and treatment. "Lifetime…”
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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis Autor Hindy, George, Tyrrell, Daniel J., Vasbinder, Alexi, Wei, Changli, Presswalla, Feriel, Wang, Hui, Blakely, Pennelope, Ozel, Ayse Bilge, Graham, Sarah, Holton, Grace H., Dowsett, Joseph, Fahed, Akl C., Amadi, Kingsley-Michael, Erne, Grace K., Tekmulla, Annika, Ismail, Anis, Launius, Christopher, Sotoodehnia, Nona, Pankow, James S., Thørner, Lise Wegner, Erikstrup, Christian, Pedersen, Ole Birger, Banasik, Karina, Brunak, Søren, Ullum, Henrik, Eugen-Olsen, Jesper, Ostrowski, Sisse Rye, Haas, Mary E., Nielsen, Jonas B., Lotta, Luca A., Engström, Gunnar, Melander, Olle, Orho-Melander, Marju, Zhao, Lili, Murthy, Venkatesh L., Pinsky, David J., Willer, Cristen J., Heckbert, Susan R., Reiser, Jochen, Goldstein, Daniel R., Desch, Karl C., Hayek, Salim S.

“…People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is…”
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Atrial fibrillation incidence and risk factors in relation to race-ethnicity and the population attributable fraction of atrial fibrillation risk factors: the Multi-Ethnic Study of Atherosclerosis Autor Rodriguez, Carlos J., Soliman, Elsayed Z., Alonso, Alvaro, Swett, Katrina, Okin, Peter M., Goff, David C., Heckbert, Susan R.

“…We studied incident atrial fibrillation (AF) in the prospective community-based Multi-Ethnic Study of Atherosclerosis (MESA). Reportedly, non-Hispanic blacks…”
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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction Autor Ntalla, Ioanna, Cartwright, James H., Hall, Amelia Weber, Tucker, Nathan R., Choi, Seung Hoan, Barnes, Michael R., Warren, Helen R., Hayward, Caroline, Marten, Jonathan, Concas, Maria Pina, Boutin, Thibaud, Lima-Costa, Maria Fernanda, Souza, Renan P., Tarazona-Santos, Eduardo, Giedraitis, Vilmantas, Foco, Luisa, Gögele, Martin, Hicks, Andrew A., Cook, James P., Lindgren, Cecilia M., Riaz, Muhammad B., Sinagra, Gianfranco, Ulivi, Sheila, Kähönen, Mika, Mishra, Pashupati P., Nikus, Kjell, Padmanabhan, Sandosh, O’Connell, Jeff R., Aeschbacher, Stefanie, Risch, Lorenz, Thériault, Sébastien, Hutri-Kähönen, Nina, Lehtimäki, Terho, Barnes, Catriona L. K., Joshi, Peter K., Isaacs, Aaron, van Duijn, Cornelia M., Gudnason, Vilmundur, Harris, Tamara B., Nadkarni, Girish N., Correa, Adolfo, Mei, Hao, Wilson, James, Müller-Nurasyid, Martina, Waldenberger, Melanie, Mangino, Massimo, Kääb, Stefan, Schramm, Katharina, Strauch, Konstantin, Cutler, Michael J., Fatkin, Diane, Olesen, Morten, Roden, Dan M., Gustav Smith, J., Biggs, Mary L., Bis, Joshua C., Sotoodehnia, Nona, Pramstaller, Peter P., Ford, Ian, Wouter Jukema, J., Macfarlane, Peter W., Trompet, Stella, Dörr, Marcus, Felix, Stephan B., Weiss, Stefan, Havulinna, Aki S., Jula, Antti, Sääksjärvi, Katri, Rotter, Jerome I., Yao, Jie, Maan, Arie C., Mook-Kanamori, Dennis O., Cucca, Francesco, Lakatta, Edward G., Qian, Yong, Lin, Honghuang, Newton-Cheh, Christopher H., Lunetta, Kathryn L., Murray, Alison D., Stricker, Bruno H., Uitterlinden, André, van den Berg, Marten E., Haessler, Jeffrey, Kooperberg, Charles, Peters, Ulrike, Reiner, Alexander P., Arking, Dan E., Boerwinkle, Eric, Soliman, Elsayed Z., Gogarten, Stephanie M., Kerr, Kathleen F., Laurie, Cathy C., Abdullah Said, M., Yldau van der Ende, M., Ramirez, Julia, Van Duijvenboden, Stefan, Arnar, David O., Thorolfsdottir, Rosa B., Ellinor, Patrick T., Lubitz, Steven A.

“…The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial…”
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DEEPMIR: a deep neural network for differential detection of cerebral microbleeds and iron deposits in MRI Autor Rashid, Tanweer, Abdulkadir, Ahmed, Nasrallah, Ilya M., Ware, Jeffrey B., Liu, Hangfan, Spincemaille, Pascal, Romero, J. Rafael, Bryan, R. Nick, Heckbert, Susan R., Habes, Mohamad

“…Lobar cerebral microbleeds (CMBs) and localized non-hemorrhage iron deposits in the basal ganglia have been associated with brain aging, vascular disease and…”
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Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007 Autor Piccini, Jonathan P, Hammill, Bradley G, Sinner, Moritz F, Jensen, Paul N, Hernandez, Adrian F, Heckbert, Susan R, Benjamin, Emelia J, Curtis, Lesley H

“…Atrial fibrillation (AF) is a common and costly problem among older persons. The frequency of AF increases with age, but representative national data about…”
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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways Autor Isaacs, Aaron, Duong, ThuyVy, Foco, Luisa, Ahmed, Farah, Brody, Jennifer A., Salman, Reem, Noordam, Raymond, Benjamins, Jan-Walter, Repetto, Linda, Concas, Maria Pina, van den Berg, Marten E., Weiss, Stefan, Baldassari, Antoine R., Bartz, Traci M., Cook, James P., Evans, Daniel S., Freudling, Rebecca, Mei, Hao, Moscati, Arden, Müller-Nurasyid, Martina, Nursyifa, Casia, Ryan, Kathleen A., Tarazona-Santos, Eduardo, van Duijvenboden, Stefan, Yao, Jie, Andreasen, Laura, Bis, Joshua C., Cutler, Michael J., Ellervik, Christina, Ellinor, Patrick T., Felix, Stephan B., Graff, Mariaelisa, Guo, Xiuqing, Heckbert, Susan R., Huang, Paul L., Hutri-Kähönen, Nina, Ikram, M. Arfan, Jackson, Rebecca D., Junttila, Juhani, Kavousi, Maryam, Kors, Jan A., Leal, Thiago P., Lemaitre, Rozenn N., Lind, Lars, Liu, Simin, MacFarlane, Peter W., Mangino, Massimo, Meitinger, Thomas, Mezzavilla, Massimo, Mishra, Pashupati P., Montasser, May E., Navarro, Pau, Nikus, Kjell, Pare, Guillaume, Patton, Kristen K., Pelliccione, Giulia, Porteous, David J., Pramstaller, Peter P., Preuss, Michael H., Risch, Lorenz, Schurmann, Claudia, Sinner, Moritz F., Stoll, Monika, Tarasov, Kirill, Taylor, Kent D., Trompet, Stella, Uitterlinden, André, Völker, Uwe, Waldenberger, Melanie, Weng, Lu-Chen, Whitsel, Eric A., Wilson, James G., Avery, Christy L., Conen, David, Dörr, Marcus, Gharib, Sina A., Girotto, Giorgia, Grarup, Niels, Hayward, Caroline, Jamshidi, Yalda, Kähönen, Mika, Kanters, Jørgen K., Lima-Costa, Maria Fernanda, Liu, Yongmei, Loos, Ruth J. F., Mook-Kanamori, Dennis O., Morris, Andrew P., O’Connell, Jeffrey R., Olesen, Morten Salling, Orini, Michele, Pattaro, Cristian, Psaty, Bruce M., Rotter, Jerome I., Stricker, Bruno, van der Harst, Pim, van Duijn, Cornelia M., Arking, Dan E., Ramirez, Julia, Sotoodehnia, Nona, Munroe, Patricia B.

“…The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT…”
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Chronic kidney disease increases risk for venous thromboembolism Autor Wattanakit, Keattiyoat, Cushman, Mary, Stehman-Breen, Catherine, Heckbert, Susan R, Folsom, Aaron R

“…Chronic kidney disease (CKD) is associated with increased risk for cardiovascular disease morbidity and mortality, but its association with incident venous…”
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New gene functions in megakaryopoiesis and platelet formation Autor Gieger, Christian, Radhakrishnan, Aparna, Cvejic, Ana, Tang, Weihong, Pistis, Giorgio, Serbanovic-Canic, Jovana, Elling, Ulrich, Goodall, Alison H., Labrune, Yann, Lopez, Lorna M., Meacham, Stuart, Sorice, Rossella, Teumer, Alexander, Ramirez-Solis, Ramiro, Ellinghaus, David, Gögele, Martin, Hottenga, Jouke-Jan, Langenberg, Claudia, Kovacs, Peter, O’Reilly, Paul F., Shin, So-Youn, Murgia, Federico, Parsa, Afshin, Stephens, Jonathan, Ellen van der Schoot, C., Allayee, Hooman, Attwood, Antony, Baumeister, Sebastian E., Biino, Ginevra, Cambien, François, Cucca, Francesco, de Boer, Rudolf A., Erdmann, Jeanette, Evans, David M., Falchi, Mario, Feng, Wei, Folsom, Aaron R., Frazer, Ian H., Gibson, Quince D., Glazer, Nicole L., Hartikainen, Anna-Liisa, Heckbert, Susan R., Hersch, Micha, Illig, Thomas, Kühnel, Brigitte, Lagou, Vasiliki, Lloyd-Jones, Heather, Lumley, Thomas, Maschio, Andrea, Mateo Leach, Irene, McKnight, Barbara, Memari, Yasin, Montgomery, Grant W., Nakamura, Yusuke, Nauck, Matthias, Nöthlings, Ute, Nolte, Ilja M., Pouta, Anneli, Ruggiero, Daniela, Sala, Cinzia, Sambrook, Jennifer, Schlessinger, David, Scott, James, Smith, Nicholas L., Snieder, Harold, Starr, John M., Stumvoll, Michael, Wilson Tang, W. H., Tenesa, Albert, Uda, Manuela, Visscher, Peter M., Völker, Uwe, Willemsen, Gonneke, Yang, Tsun-Po, Zitting, Paavo, Dedoussis, George V., Metspalu, Andres, Shuldiner, Alan R., Joost van Pelt, L., Zwaginga, Jaap-Jan, Franke, Andre, Froguel, Philippe, Jarvelin, Marjo-Riitta, Martin, Nicholas G., Meisinger, Christa, Psaty, Bruce M., Spector, Timothy D., Wareham, Nicholas J., Akkerman, Jan-Willem N., Ciullo, Marina, Deloukas, Panos, Jupe, Steve, Khadake, Jyoti, Kooner, Jaspal S., Penninger, Josef, Stemple, Derek, Wernisch, Lorenz, Sanna, Serena, Rendon, Augusto, Soranzo, Nicole

“…Platelets are the second most abundant cell type in blood and are essential for maintaining haemostasis. Their count and volume are tightly controlled within…”
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Fragmented sinoatrial dynamics in the prediction of atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis Autor Costa, Madalena D, Redline, Susan, Soliman, Elsayed Z, Goldberger, Ary L, Heckbert, Susan R

“…Heart rate fragmentation (HRF), a marker of abnormal sinoatrial dynamics, was shown to be associated with incident cardiovascular events in the Multi-Ethnic…”
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eGFR and Albuminuria in Relation to Risk of Incident Atrial Fibrillation: A Meta-Analysis of the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study Autor Bansal, Nisha, Zelnick, Leila R, Alonso, Alvaro, Benjamin, Emelia J, de Boer, Ian H, Deo, Rajat, Katz, Ronit, Kestenbaum, Bryan, Mathew, Jehu, Robinson-Cohen, Cassianne, Sarnak, Mark J, Shlipak, Michael G, Sotoodehnia, Nona, Young, Bessie, Heckbert, Susan R

“…The incidence of atrial fibrillation is high in ESRD, but limited data are available on the incidence of atrial fibrillation across a broad range of kidney…”
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Association of Elevated NT-proBNP With Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis (MESA) Autor Liu, Chia-Ying, Heckbert, Susan R, Lai, Shenghan, Ambale-Venkatesh, Bharath, Ostovaneh, Mohammad R, McClelland, Robyn L, Lima, João A C, Bluemke, David A

“…Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) is considered a marker that is expressed in response to myocardial strain and possibly fibrosis…”
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Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink Autor Carr, Daniel F., Francis, Ben, Jorgensen, Andrea L., Zhang, Eunice, Chinoy, Hector, Heckbert, Susan R., Bis, Joshua C., Brody, Jennifer A., Floyd, James S., Psaty, Bruce M., Molokhia, Mariam, Lapeyre‐Mestre, Maryse, Conforti, Anita, Alfirevic, Ana, Staa, Tjeerd, Pirmohamed, Munir

“…Statins can be associated with myopathy. We have undertaken a genomewide association study (GWAS) to discover and validate genetic risk factors for…”
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