Search Results - "Healy, Brian C"

Exploration of machine learning techniques in predicting multiple sclerosis disease course by Zhao, Yijun, Healy, Brian C., Rotstein, Dalia, Guttmann, Charles R. G., Bakshi, Rohit, Weiner, Howard L., Brodley, Carla E., Chitnis, Tanuja

“…To explore the value of machine learning methods for predicting multiple sclerosis disease course. 1693 CLIMB study patients were classified as increased…”
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A probiotic modulates the microbiome and immunity in multiple sclerosis by Tankou, Stephanie K., Regev, Keren, Healy, Brian C., Tjon, Emily, Laghi, Luca, Cox, Laura M., Kivisäkk, Pia, Pierre, Isabelle V., Hrishikesh, Lokhande, Gandhi, Roopali, Cook, Sandra, Glanz, Bonnie, Stankiewicz, James, Weiner, Howard L.

“…Objective Effect of a probiotic on the gut microbiome and peripheral immune function in healthy controls and relapsing‐remitting multiple sclerosis (MS)…”
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Gut Microbiome in Progressive Multiple Sclerosis by Cox, Laura M., Maghzi, Amir Hadi, Liu, Shirong, Tankou, Stephanie K., Dhang, Fyonn H., Willocq, Valerie, Song, Anya, Wasén, Caroline, Tauhid, Shahamat, Chu, Renxin, Anderson, Mark C., De Jager, Philip L., Polgar‐Turcsanyi, Mariann, Healy, Brian C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Weiner, Howard L.

“…Objective This study was undertaken to investigate the gut microbiome in progressive multiple sclerosis (MS) and how it relates to clinical disease. Methods We…”
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Association between anxiety and mortality in patients with coronary artery disease: A meta-analysis by Celano, Christopher M., Millstein, Rachel A., Bedoya, C. Andres, Healy, Brian C., Roest, Annelieke M., Huffman, Jeff C.

“…Depression and anxiety are common in patients with coronary artery disease (CAD). Although depression clearly has been associated with mortality in this…”
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The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis by Hemond, Christopher C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Healy, Brian C.

“…Background Serum hematological indices such as the neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) have been used as biomarkers of…”
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Investigation of probiotics in multiple sclerosis by Tankou, Stephanie K, Regev, Keren, Healy, Brian C, Cox, Laura M, Tjon, Emily, Kivisakk, Pia, Vanande, Isabelle P, Cook, Sandra, Gandhi, Roopali, Glanz, Bonnie, Stankiewicz, James, Weiner, Howard L

“…None of the disease-modifying therapies (DMTs) currently being used for the management of multiple sclerosis (MS) are 100% effective. In addition, side effects…”
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microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance by Fujiwara, Mai, Raheja, Radhika, Garo, Lucien P., Ajay, Amrendra K., Kadowaki-Saga, Ryoko, Karandikar, Sukrut H., Gabriely, Galina, Krishnan, Rajesh, Beynon, Vanessa, Paul, Anu, Patel, Amee, Saxena, Shrishti, Hu, Dan, Healy, Brian C., Chitnis, Tanuja, Gandhi, Roopali, Weiner, Howard L., Murugaiyan, Gopal

“…A disequilibrium between immunosuppressive Tregs and inflammatory IL-17-producing Th17 cells is a hallmark of autoimmune diseases, including multiple sclerosis…”
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Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis by Raheja, Radhika, Regev, Keren, Healy, Brian C., Mazzola, Maria Antonietta, Beynon, Vanessa, Von Glehn, Felipe, Paul, Anu, Diaz‐Cruz, Camilo, Gholipour, Taha, Glanz, Bonnie I., Kivisakk, Pia, Chitnis, Tanuja, Weiner, Howard L., Berry, James D., Gandhi, Roopali

“…ABSTRACT Introduction: Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease…”
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Novel serum biomarker associations with 7 Tesla MRI-defined cortical lesions, leptomeningeal enhancement, and deep gray matter volume in early multiple sclerosis by Miclea, Andrei, Zurawski, Jonathan, Healy, Brian C., Saxena, Shrishti, Lokhande, Hrishikesh, Quattrucci, Molly, Chu, Renxin, Weiner, Howard L., Bakshi, Rohit, Chitnis, Tanuja

“…Gray matter demyelinating lesions, brain atrophy and meningeal inflammation are hypothesized to be relevant in multiple sclerosis (MS) disease pathogenesis,…”
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Feasibility and utility of positive psychology exercises for suicidal inpatients by Huffman, Jeff C., DuBois, Christina M., Healy, Brian C., Boehm, Julia K., Kashdan, Todd B., Celano, Christopher M., Denninger, John W., Lyubomirsky, Sonja

“…The objective was to assess the feasibility and acceptability of nine positive psychology exercises delivered to patients hospitalized for suicidal thoughts or…”
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Early miR-320b and miR-25-3p miRNA levels correlate with multiple sclerosis severity at 10 years: a cohort study by Gonzalez-Martinez, Alicia, Bose, Gauruv, Lokhande, Hrishikesh, Saxena, Shrishti, Healy, Brian C., Polgar-Turcsanyi, Mariann, Weiner, Howard L., Chitnis, Tanuja

“…Background Multiple sclerosis (MS) is a chronic demyelinating autoimmune disorder which may cause long-term disability. MicroRNA (miRNA) are stable, non-coding…”
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Whole brain and deep gray matter atrophy detection over 5 years with 3T MRI in multiple sclerosis using a variety of automated segmentation pipelines by Chu, Renxin, Kim, Gloria, Tauhid, Shahamat, Khalid, Fariha, Healy, Brian C., Bakshi, Rohit

“…Cerebral atrophy is common in multiple sclerosis (MS) and selectively involves gray matter (GM). Several fully automated methods are available to measure whole…”
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miRNA 548a-3p as biomarker of NEDA-3 at 2 years in multiple sclerosis patients treated with fingolimod by Gonzalez-Martinez, Alicia, Patel, Rohit, Healy, Brian C., Lokhande, Hrishikesh, Paul, Anu, Saxena, Shrishti, Polgar-Turcsanyi, Mariann, Weiner, Howard L., Chitnis, Tanuja

“…Background Multiple sclerosis (MS) is a disabling autoimmune demyelinating disorder affecting young people and causing significant disability. In the last…”
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Work Productivity in Relapsing Multiple Sclerosis: Associations with Disability, Depression, Fatigue, Anxiety, Cognition, and Health-Related Quality of Life by Glanz, Bonnie I., Dégano, Irene R., Rintell, David J., Chitnis, Tanuja, Weiner, Howard L., Healy, Brian C.

“…To characterize work productivity in relapsing multiple sclerosis (MS) by using a work productivity scale and to identify associations between work…”
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Comparison of dimethyl fumarate and interferon outcomes in an MS cohort by Sattarnezhad, Neda, Healy, Brian C., Baharnoori, Moogeh, Diaz-Cruz, Camilo, Stankiewicz, James, Weiner, Howard L., Chitnis, Tanuja

“…Background To compare the effectiveness of dimethyl fumarate (DMF) with subcutaneous interferon beta-1a (IFNβ-1a) in controlling disease activity in patients…”
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Accounting for Withdrawal of Life-Sustaining Treatment in the Analysis of Traumatic Brain Injury Studies by Healy, Brian C., Edlow, Brian L., Bodien, Yelena G.

“…Studies that aim to evaluate outcomes after severe traumatic brain injury (TBI) must account for patients who die after withdrawal of life-sustaining treatment…”
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An Adaptive, Algorithm-based Text Message Intervention to Promote Health Behavior Adherence in Type 2 Diabetes: Treatment Development and Proof-of-Concept Trial by Celano, Christopher M, Massey, Christina, Long, Jessica, Kim, Sonia, Velasquez, Olivia, Healy, Brian C, Wexler, Deborah J, Madva, Elizabeth N, Huffman, Jeff C

“…Most individuals with type 2 diabetes (T2D) struggle to adhere to one or more health behaviors. Text message interventions (TMIs) have the potential to improve…”
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Serum glial fibrillary acidic protein predicts disease progression in multiple sclerosis by Madill, Evan, Healy, Brian C., Molazadeh, Negar, Polgar‐Turcsanyi, Mariann, Glanz, Bonnie I., Weiner, Howard L., Chitnis, Tanuja

“…Objective Glial fibrillary acidic protein (GFAP) is expressed in astrocytes and may be a useful marker of non‐active progressive multiple sclerosis (MS). We…”
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Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects by Chitnis, Tanuja, Kaskow, Belinda J., Case, Junning, Hanus, Katherine, Li, Zhenhua, Varghese, Johnna F., Healy, Brian C., Gauthier, Christian, Saraceno, Taylor J., Saxena, Shrishti, Lokhande, Hrishikesh, Moreira, Thais G., Zurawski, Jonathan, Roditi, Rachel E., Bergmark, Regan W., Giovannoni, Federico, Torti, Maria F., Li, Zhaorong, Quintana, Francisco, Clementi, William A., Shailubhai, Kunwar, Weiner, Howard L., Baecher-Allan, Clare M.

“…Parenteral anti-CD3 Mab (OKT3) has been used to treat transplant rejection and parental administration of a humanized anti-CD3 Mab (Teplizumab) showed positive…”
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Temporal association of sNfL and gad‐enhancing lesions in multiple sclerosis by Rosso, Mattia, Gonzalez, Cindy T., Healy, Brian C., Saxena, Shrishti, Paul, Anu, Bjornevik, Kjetil, Kuhle, Jens, Benkert, Pascal, Leppert, David, Guttmann, Charles, Bakshi, Rohit, Weiner, Howard L., Chitnis, Tanuja

“…Objective Multiple sclerosis (MS) is an autoimmune demyelinating disorder, which is characterized by relapses and remissions. Serum neurofilament light chain…”
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