Search Results - "Höftberger, Romana"
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A clinical approach to diagnosis of autoimmune encephalitis
ISSN: 1474-4422, 1474-4465, 1474-4465Published: England Elsevier Ltd 01.04.2016Published in Lancet neurology (01.04.2016)“…Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune encephalitis…”
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The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody
ISSN: 0001-6322, 1432-0533, 1432-0533Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2020Published in Acta neuropathologica (01.05.2020)“…We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG) antibody associated disorders (MOGAD) in an archival autopsy/biopsy…”
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The influence of brain iron on myelin water imaging
ISSN: 1053-8119, 1095-9572, 1095-9572Published: United States Elsevier Inc 01.10.2019Published in NeuroImage (Orlando, Fla.) (01.10.2019)“…With myelin playing a vital role in normal brain integrity and function and thus in various neurological disorders, myelin sensitive magnetic resonance imaging…”
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Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging
ISSN: 0001-6322, 1432-0533Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2017Published in Acta neuropathologica (01.01.2017)“…In multiple sclerosis (MS), iron accumulates inside activated microglia/macrophages at edges of some chronic demyelinated lesions, forming rims. In…”
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Overlapping demyelinating syndromes and anti-N-methyl-D-aspartate receptor encephalitis
ISSN: 0364-5134, 1531-8249, 1531-8249Published: United States Blackwell Publishing Ltd 01.03.2014Published in Annals of neurology (01.03.2014)“…Objective To report the clinical, radiological, and immunological association of demyelinating disorders with anti–N‐methyl‐D‐aspartate receptor (NMDAR)…”
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Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients
ISSN: 1526-632X, 1526-632XPublished: United States 16.06.2015Published in Neurology (16.06.2015)“…We report the clinical features, comorbidities, and outcome of 22 newly identified patients with antibodies to the…”
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Herpes simplex virus encephalitis is a trigger of brain autoimmunity
ISSN: 0364-5134, 1531-8249, 1531-8249Published: United States Blackwell Publishing Ltd 01.02.2014Published in Annals of neurology (01.02.2014)“…In 5 prospectively diagnosed patients with relapsing post–herpes simplex encephalitis (HSE), N‐methyl‐D‐aspartate receptor (NMDAR) antibodies were identified…”
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Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases
ISSN: 1664-3224, 1664-3224Published: Switzerland Frontiers Media S.A 08.05.2017Published in Frontiers in immunology (08.05.2017)“…Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig) superfamily, is a myelin protein solely expressed at the outermost surface of…”
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Synthesized myelin and iron stainings from 7T multi-contrast MRI via deep learning
ISSN: 1053-8119, 1095-9572, 1095-9572Published: United States Elsevier Inc 01.09.2025Published in NeuroImage (Orlando, Fla.) (01.09.2025)“…•Synthesized myelin and iron stainings can be generated from 7T MRI data via deep learning.•Combined T1, R2*, and QSM gave the best results for myelin staining…”
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Neuropathological criteria of anti-IgLON5-related tauopathy
ISSN: 0001-6322, 1432-0533Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2016Published in Acta neuropathologica (01.10.2016)“…We recently reported a novel neurological syndrome characterized by a unique NREM and REM parasomnia with sleep apnea and stridor, accompanied by bulbar…”
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Endoscopic Transsphenoidal Surgery of Microprolactinomas: A Reappraisal of Cure Rate Based on Radiological Criteria
ISSN: 0148-396X, 1524-4040, 1524-4040Published: United States Oxford University Press 01.10.2019Published in Neurosurgery (01.10.2019)“…Abstract Background Current standard treatment of microprolactinomas is dopamine agonist therapy. As this drug treatment is lifelong in up to 80% of cases,…”
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Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy
ISSN: 1460-2156, 1460-2156Published: England 07.05.2021Published in Brain (London, England : 1878) (07.05.2021)“…Previous studies have described the clinical, serological and pathological features of patients with chronic inflammatory demyelinating polyradiculoneuropathy…”
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The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain
ISSN: 1460-2156Published: England 01.03.2016Published in Brain (London, England : 1878) (01.03.2016)“…Multiple sclerosis is a chronic inflammatory disease with primary demyelination and neurodegeneration in the central nervous system. In our study we analysed…”
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Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica
ISSN: 0001-6322, 1432-0533, 1432-0533Published: Berlin/Heidelberg Springer-Verlag 01.06.2013Published in Acta neuropathologica (01.06.2013)“…Neuromyelitis optica (NMO) is an autoimmune disease targeting aquaporin 4 (AQP4), localized mainly at the astrocytic foot processes. Loss of AQP4 and glial…”
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Diagnostic Approach and Treatment Regimens in Adult Patients Suffering from Antibody- mediated or Paraneoplastic Encephalitis
ISSN: 1873-4286, 1873-4286Published: United Arab Emirates 01.01.2022Published in Current pharmaceutical design (01.01.2022)“…Identification of patients with antibody-mediated encephalitis poses a diagnostic challenge, and any delay in that aspect will increase the interval until the…”
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Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
ISSN: 1742-2094, 1742-2094Published: London BioMed Central 25.10.2017Published in Journal of neuroinflammation (25.10.2017)“…Background Antibodies to the myelin oligodendrocyte glycoprotein (MOG) are associated with a subset of inflammatory demyelinating diseases of the central…”
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Disease-specific molecular events in cortical multiple sclerosis lesions
ISSN: 1460-2156, 1460-2156Published: England 01.06.2013Published in Brain (London, England : 1878) (01.06.2013)“…Cortical lesions constitute an important part of multiple sclerosis pathology. Although inflammation appears to play a role in their formation, the mechanisms…”
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Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons
ISSN: 1946-6242, 1946-6242Published: United States 13.04.2022Published in Science translational medicine (13.04.2022)“…The mechanisms underlying the chronicity of autoimmune diseases of the central nervous system (CNS) are largely unknown. In particular, it is unclear whether…”
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Children with multiphasic disseminated encephalomyelitis and antibodies to the myelin oligodendrocyte glycoprotein (MOG): Extending the spectrum of MOG antibody positive diseases
ISSN: 1477-0970, 1477-0970Published: England 01.12.2016Published in Multiple sclerosis (01.12.2016)“…Myelin oligodendrocyte glycoprotein (MOG) antibodies have been described in children with acute disseminated encephalomyelitis (ADEM), recurrent optic…”
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Longitudinal CSF Findings in Autoimmune Encephalitis—A Monocentric Cohort Study
ISSN: 1664-3224, 1664-3224Published: Switzerland Frontiers Media SA 22.03.2021Published in Frontiers in Immunology (22.03.2021)“…Autoimmune encephalitis (AIE) poses a diagnostic challenge due to its heterogeneous clinical presentation, which overlaps with various neurological and…”
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