Suchergebnisse - "Guo, Changyong"

Calcium Permeable-AMPA Receptors and Excitotoxicity in Neurological Disorders von Guo, Changyong, Ma, Yao-Ying

“… Excitotoxicity is one of the primary mechanisms of cell loss in a variety of diseases of the central and peripheral nervous systems. Other than the previously …”
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Identification of a cell of origin for human prostate cancer von Goldstein, Andrew S, Huang, Jiaoti, Guo, Changyong, Garraway, Isla P, Witte, Owen N

“… Luminal cells are believed to be the cells of origin for human prostate cancer, because the disease is characterized by luminal cell expansion and the absence …”
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Recent advances in aptamer-based targeted drug delivery systems for cancer therapy von Gao, Fei, Yin, Jianhui, Chen, Yan, Guo, Changyong, Hu, Honggang, Su, Jiacan

“… The past decade has become an important strategy in precision medicine for the targeted therapy of many diseases, expecially various types of cancer. As a …”
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Amyloid-β oligomers in the nucleus accumbens decrease motivation via insertion of calcium-permeable AMPA receptors von Guo, Changyong, Wen, Di, Zhang, Yihong, Mustaklem, Richie, Mustaklem, Basil, Zhou, Miou, Ma, Tao, Ma, Yao-Ying

“… It is essential to identify the neuronal mechanisms of Alzheimer's Disease (AD)-associated neuropsychiatric symptoms, e.g., apathy, before improving the life …”
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Clinical efficacy of Femoral Neck System for treatment of unstable femoral neck fractures in young adults von Guo, ChangYong, Huang, JiaPing, Chen, ZhiBiao, Cai, ZeMing, Cai, TaoYi

“… Objective This study was performed to evaluate the mid-term clinical efficacy of the Femoral Neck System (FNS) (DePuy Synthes, Zuchwil, Switzerland) in …”
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Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections von Ma, Yao-Ying, Lee, Brian R, Wang, Xiusong, Guo, Changyong, Liu, Lei, Cui, Ranji, Lan, Yan, Balcita-Pedicino, Judith J, Wolf, Marina E, Sesack, Susan R, Shaham, Yavin, Schlüter, Oliver M, Huang, Yanhua H, Dong, Yan

“… Glutamatergic projections from the medial prefrontal cortex (mPFC) to nucleus accumbens (NAc) contribute to cocaine relapse. Here we show that silent …”
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Precise HER2 Protein Degradation via Peptide‐Conjugated Photodynamic Therapy for Enhanced Breast Cancer Immunotherapy von Guo, Changyong, Gao, Fei, Wu, Guoyuan, Li, Jinqiu, Sheng, Chunquan, He, Shipeng, Hu, Honggang

“… Breast cancer, the most prevalent malignancy among women, frequently exhibits high HER2 expression, making HER2 a critical therapeutic target. Traditional …”
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Tryptophan-specific peptide modification through metal-free photoinduced N-H alkylation employing N-aryl glycines von Yin, Jianhui, Huang, Wenjing, Guo, Changyong, Liu, Chao, Gao, Fei, Hu, Honggang

“… Tryptophan (Trp) carries a unique heteroaromatic indole side chain and plays a critical role in peptide or protein modification. Herein, we have reported a …”
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Shape–intensity prior level set combining probabilistic atlas and probability map constrains for automatic liver segmentation from abdominal CT images von Wang, Jinke, Cheng, Yuanzhi, Guo, Changyong, Wang, Yadong, Tamura, Shinichi

“… Purpose Propose a fully automatic 3D segmentation framework to segment liver on challenging cases that contain the low contrast of adjacent organs and the …”
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Machine Learning-Based Malicious X.509 Certificates’ Detection von Li, Jiaxin, Zhang, Zhaoxin, Guo, Changyong

“… X.509 certificates play an important role in encrypting the transmission of data on both sides under HTTPS. With the popularization of X.509 certificates, more …”
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Polymer-assisted PD-L1 degradation and targeted photodynamic therapy synergize to suppress immunodeficient tumors von Guo, Changyong, He, Shipeng, Shen, Huaxing, Cong, Wei, Li, Jinqiu, Ji, Yajing, Huang, Wenjing, Gao, Fei, Hu, Honggang

“… Checkpoint blockade immunotherapy has emerged as a transformative approach in cancer treatment by activating tumor-infiltrating T cells. However, the efficacy …”
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Automatic segmentation technique for acetabulum and femoral head in CT images von Cheng, Yuanzhi, Zhou, Shengjun, Wang, Yadong, Guo, Changyong, Bai, Jing, Tamura, Shinichi

“… Segmentation of the femoral head and proximal acetabulum from three dimensional (3D) CT data is essential for patient specific planning and simulation of hip …”
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Identification of CD166 as a Surface Marker for Enriching Prostate Stem/Progenitor and Cancer Initiating Cells von Jiao, Jing, Hindoyan, Antreas, Wang, Shunyou, Tran, Linh M., Goldstein, Andrew S., Lawson, Devon, Chen, Donghui, Li, Yunfeng, Guo, Changyong, Zhang, Baohui, Fazli, Ladan, Gleave, Martin, Witte, Owen N., Garraway, Isla P., Wu, Hong

“… New therapies for late stage and castration resistant prostate cancer (CRPC) depend on defining unique properties and pathways of cell sub-populations capable …”
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Assessing the Structural Vulnerability of Online Social Networks in Empirical Data von Zhang, Dayong, Guo, Changyong, Zhang, Zhaoxin, Long, Gang

“… Assessing the structural vulnerability of online social networks has been one of the most engaging topics recently, which is quite essential and beneficial to …”
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Decoding Secondary Motor Cortex Neuronal Activity During Cocaine Self-Administration: Insights From Longitudinal In Vivo Calcium Imaging von Chen, Yingying, Fu, Haoying, Korada, Amith, Lange, Michal A., Rayanki, Chandrashekar, Lu, Tao, Lai, Dongbing, Fang, Shiaofen, Guo, Changyong, Ma, Yao-Ying

“… We recently reported that cocaine relapse risk is linked to hyperexcitability in the secondary motor cortex (M2) after prolonged withdrawal following …”
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Epcam, CD44, and CD49f Distinguish Sphere-Forming Human Prostate Basal Cells from a Subpopulation with Predominant Tubule Initiation Capability von Guo, Changyong, Liu, Haibo, Zhang, Bao-Hui, Cadaneanu, Radu M., Mayle, Aqila M., Garraway, Isla P.

“… Human prostate basal cells expressing alpha-6 integrin (CD49f(Hi)) and/or CD44 form prostaspheres in vitro. This functional trait is often correlated with …”
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Sex-Specific Impact of Fkbp5 on Hippocampal Response to Acute Alcohol Injection: Involvement in Alterations of Metabolism-Related Pathways von Williams, Kent E., Zou, Yi, Qiu, Bin, Kono, Tatsuyoshi, Guo, Changyong, Garcia, Dawn, Chen, Hanying, Graves, Tamara, Lai, Zhao, Evans-Molina, Carmella, Ma, Yao-Ying, Liangpunsakul, Suthat, Yong, Weidong, Liang, Tiebing

“… High levels of alcohol intake alter brain gene expression and can produce long-lasting effects. FK506-binding protein 51 (FKBP51) encoded by Fkbp5 is a …”
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Accuracy Limits for the Thickness Measurement of the Hip Joint Cartilage in 3-D MR Images: Simulation and Validation von Cheng, Yuanzhi, Guo, Changyong, Wang, Yadong, Bai, Jing, Tamura, Shinichi

“… This paper describes a theoretical simulation method for ascertaining the inherent limits on the accuracy of thickness measurement of hip joint cartilage in …”
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Large power microwave nonlinear effects on multifunction amplifier chip for Ka-band T/R module of phased array radar von Guo, Guo, Gu, Ling, Wu, Ruowu, Xu, Xiong, Zhou, Taifu, Niu, Xinjian, Liu, Yinghui, Wang, Hui, Wei, Yanyu, Guo, Changyong

“… Nonlinear effects of large power millimeter wave on critical chips for the T/R module of phased array radar is experimental studied and analyzed in this paper …”
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A technique for visualization and mapping of local cartilage thickness changes in MR images of osteoarthritic knee von Ge, Quanxu, Cheng, Yuanzhi, Bi, Kesen, Guo, Changyong, Bai, Jing, Tamura, Shinichi

“… The aim of this paper is to describe a technique for the visualization and mapping of focal, local cartilage thickness changes over time in magnetic resonance …”
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