Výsledky vyhľadávania - "Grant, C. C."

Hemophagocytic lymphohistiocytosis: An update on pathogenesis, diagnosis, and therapy Autor Griffin, Georgia, Shenoi, Susan, Hughes, Grant C.

“…Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening state of immune hyperactivation that arises in the setting of genetic mutations and…”
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Variability in donor leukocyte counts confound the use of common RNA sequencing data normalization strategies in transcriptomic biomarker studies performed with whole blood Autor O’Connell, Grant C.

“…Gene expression data generated from whole blood via next generation sequencing is frequently used in studies aimed at identifying mRNA-based biomarker panels…”
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The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries Autor Grant, Michael C., Geoghegan, Luke, Arbyn, Marc, Mohammed, Zakaria, McGuinness, Luke, Clarke, Emily L., Wade, Ryckie G.

“…To limit the spread of SARS-CoV-2, an evidence-based understanding of the symptoms is critical to inform guidelines for quarantining and testing. The most…”
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Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition Autor Grant, Oliver C., Montgomery, David, Ito, Keigo, Woods, Robert J.

“…Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from SARS-CoV-2, based on reported 3D structures and glycomics data for the…”
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Progesterone and autoimmune disease Autor Hughes, Grant C.

“…Sexual dimorphism in human immune systems is most apparent in the female predominance of certain autoimmune diseases (ADs) like systemic lupus erythematosus…”
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Deep learning enables satellite-based monitoring of large populations of terrestrial mammals across heterogeneous landscape Autor Wu, Zijing, Zhang, Ce, Gu, Xiaowei, Duporge, Isla, Hughey, Lacey F., Stabach, Jared A., Skidmore, Andrew K., Hopcraft, J. Grant C., Lee, Stephen J., Atkinson, Peter M., McCauley, Douglas J., Lamprey, Richard, Ngene, Shadrack, Wang, Tiejun

“…New satellite remote sensing and machine learning techniques offer untapped possibilities to monitor global biodiversity with unprecedented speed and…”
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Cross-boundary human impacts compromise the Serengeti-Mara ecosystem Autor Veldhuis, Michiel P, Ritchie, Mark E, Ogutu, Joseph O, Morrison, Thomas A, Beale, Colin M, Estes, Anna B, Mwakilema, William, Ojwang, Gordon O, Parr, Catherine L, Probert, James, Wargute, Patrick W, Hopcraft, J Grant C, Olff, Han

“…Protected areas provide major benefits for humans in the form of ecosystem services, but landscape degradation by human activity at their edges may compromise…”
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Modulation of autoimmune rheumatic diseases by oestrogen and progesterone Autor Hughes, Grant C., Choubey, Divaker

“…Key Points Sexual dimorphism in the risk and expression of human autoimmune rheumatic diseases involves the immunomodulatory effects of postpubertal levels of…”
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Neutrophil extracellular traps as a potential source of autoantigen in cocaine-associated autoimmunity Autor Lood, Christian, Hughes, Grant C

“…Exposure to illicit cocaine and its frequent adulterant, levamisole, is associated with ANCAs targeting neutrophil elastase (NE), neutropenia and…”
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Declining oxygen in the global ocean and coastal waters Autor Breitburg, Denise, Levin, Lisa A, Oschlies, Andreas, Grégoire, Marilaure, Chavez, Francisco P, Conley, Daniel J, Garçon, Véronique, Gilbert, Denis, Gutiérrez, Dimitri, Isensee, Kirsten, Jacinto, Gil S, Limburg, Karin E, Montes, Ivonne, Naqvi, S W A, Pitcher, Grant C, Rabalais, Nancy N, Roman, Michael R, Rose, Kenneth A, Seibel, Brad A, Telszewski, Maciej, Yasuhara, Moriaki, Zhang, Jing

“…Oxygen is fundamental to life. Not only is it essential for the survival of individual animals, but it regulates global cycles of major nutrients and carbon…”
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Polarity-switching top coats enable orientation of sub-10-nm block copolymer domains Autor Bates, Christopher M, Seshimo, Takehiro, Maher, Michael J, Durand, William J, Cushen, Julia D, Dean, Leon M, Blachut, Gregory, Ellison, Christopher J, Willson, C Grant

“…Block copolymers (BCPs) must necessarily have high interaction parameters (χ), a fundamental measure of block incompatibility, to self-assemble into…”
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Multiple stressors unpredictably affect primary producers and decomposition in a model freshwater ecosystem Autor Saqira, Sajida, Chariton, Anthony, Hose, Grant C.

“…Freshwater ecosystems are affected by various stressors, such as contamination and exotic species, making them amongst the most imperilled biological systems…”
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Mitochondrial calcium cycling in neuronal function and neurodegeneration Autor Walters, Grant C., Usachev, Yuriy M.

“…Mitochondria are essential for proper cellular function through their critical roles in ATP synthesis, reactive oxygen species production, calcium (Ca 2+ )…”
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Longest terrestrial migrations and movements around the world Autor Joly, Kyle, Gurarie, Eliezer, Sorum, Mathew S., Kaczensky, Petra, Cameron, Matthew D., Jakes, Andrew F., Borg, Bridget L., Nandintsetseg, Dejid, Hopcraft, J. Grant C., Buuveibaatar, Bayarbaatar, Jones, Paul F., Mueller, Thomas, Walzer, Chris, Olson, Kirk A., Payne, John C., Yadamsuren, Adiya, Hebblewhite, Mark

“…Long-distance terrestrial migrations are imperiled globally. We determined both round-trip migration distances (straight-line measurements between migratory…”
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The impact of small groups on pre‐ and postcopulatory sexual selection in polyandrous populations Autor McDonald, Grant C.

“…Sexual selection is a key evolutionary force but varies widely between populations. Two key factors that influence sexual selection are the extent to which…”
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Analytical Models for Secular Descents in Hierarchical Triple Systems Autor Weldon, Grant C., Naoz, Smadar, Hansen, Bradley M. S.

“…Three-body systems are prevalent in nature, from planetary to stellar to supermassive black hole scales. In a hierarchical triple system, oscillations of the…”
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Virtual discovery of melatonin receptor ligands to modulate circadian rhythms Autor Stein, Reed M., Kang, Hye Jin, McCorvy, John D., Glatfelter, Grant C., Jones, Anthony J., Che, Tao, Slocum, Samuel, Huang, Xi-Ping, Savych, Olena, Moroz, Yurii S., Stauch, Benjamin, Johansson, Linda C., Cherezov, Vadim, Kenakin, Terry, Irwin, John J., Shoichet, Brian K., Roth, Bryan L., Dubocovich, Margarita L.

“…The neuromodulator melatonin synchronizes circadian rhythms and related physiological functions through the actions of two G-protein-coupled receptors: MT 1…”
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Donor white blood cell differential is the single largest determinant of whole blood gene expression patterns Autor O'Connell, Grant C., Wang, Jing, Smothers, Christine

“…It has become widely accepted that sample cellular composition is a significant determinant of the gene expression patterns observed in any transcriptomic…”
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Livestock movement informs the risk of disease spread in traditional production systems in East Africa Autor Ekwem, Divine, Morrison, Thomas A., Reeve, Richard, Enright, Jessica, Buza, Joram, Shirima, Gabriel, Mwajombe, James K., Lembo, Tiziana, Hopcraft, J. Grant C.

“…In Africa, livestock are important to local and national economies, but their productivity is constrained by infectious diseases. Comprehensive information on…”
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FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake Autor Jensen-Cody, Sharon O, Flippo, Kyle H, Claflin, Kristin E, Yavuz, Yavuz, Sapouckey, Sarah A, Walters, Grant C, Usachev, Yuriy M, Atasoy, Deniz, Gillum, Matthew P, Potthoff, Matthew J

“…Fibroblast growth factor 21 (FGF21) is an endocrine hormone produced by the liver that regulates nutrient and metabolic homeostasis. FGF21 production is…”
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