Výsledky vyhľadávania - "Gompels, Mark"

Peripheral B Cell Deficiency and Predisposition to Viral Infections: The Paradigm of Immune Deficiencies Autor Grammatikos, Alexandros, Donati, Matthew, Johnston, Sarah L., Gompels, Mark M.

“…In the era of COVID-19, understanding how our immune system responds to viral infections is more pertinent than ever. Immunodeficiencies with very low or…”
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Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy Autor May, Margaret T, Gompels, Mark, Delpech, Valerie, Porter, Kholoud, Orkin, Chloe, Kegg, Stephen, Hay, Phillip, Johnson, Margaret, Palfreeman, Adrian, Gilson, Richard, Chadwick, David, Martin, Fabiola, Hill, Teresa, Walsh, John, Post, Frank, Fisher, Martin, Ainsworth, Jonathan, Jose, Sophie, Leen, Clifford, Nelson, Mark, Anderson, Jane, Sabin, Caroline

“…The objective of this study is to estimate life expectancies of HIV-positive patients conditional on response to antiretroviral therapy (ART). Patients aged…”
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Efficacy and Safety of Donidalorsen for Hereditary Angioedema Autor Riedl, Marc A., Tachdjian, Raffi, Lumry, William R., Craig, Timothy, Karakaya, Gül, Gelincik, Asli, Stobiecki, Marcin, Jacobs, Joshua S., Gokmen, Nihal M., Reshef, Avner, Gompels, Mark M., Manning, Michael E., Bordone, Laura, Newman, Kenneth B., Treadwell, Sabrina, Wang, Sophie, Yarlas, Aaron, Cohn, Danny M.

“…A randomized, controlled trial of donidalorsen, which targets prekallikrein mRNA, in patients with hereditary angioedema showed a lower attack rate in the…”
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The wrong Spirochaete? Acute kidney injury in a returning traveller with syphilis – a case report Autor Cook, Hannah, Gompels, Mark

“…Background Syphilis has seen an increased incidence in recent years and can have serious and irreversible consequences if left un-diagnosed and untreated. This…”
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CNS demyelination associated with immune dysregulation and a novel CTLA-4 variant Autor Kaninia, Stefania, Grammatikos, Alexandros, Urankar, Kathryn, Renowden, Shelley A, Patel, Nikunj K, Gompels, Mark M, Rice, Claire M

“…The cytotoxic T-lymphocyte antigen-4 (CTLA-4) pathway acts as a negative immune regulator of T-cell activation and promotes self-tolerance. We report the first…”
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Associations of depression and anxiety symptoms with sexual behaviour in women and heterosexual men attending sexual health clinics: a cross-sectional study Autor Coyle, Rachel Margaret, Lampe, Fiona C, Miltz, Ada Rose, Sewell, Janey, Anderson, Jane, Apea, Vanessa, Collins, Simon, Dhairyawan, Rageshri, Johnson, Anne M, Lascar, Monica, Mann, Sue, O'Connell, Rebecca, Sherr, Lorraine, Speakman, Andrew, Tang, Alan, Phillips, Andrew N, Rodger, Alison, Gilson, Richard J, Asboe, David, Nwokolo, Nneka C, Clarke, Amanda, Gompels, Mark M, Allan, Sris, Scott, Christopher, Day, Sara, Fisher, Martin, Lascar, Monica, Farazmand, Paymaneh, Mann, Susan, Dhar, Jyoti, Ivens, Daniel R, Sadiq, Tariq, Hart, Graham J, Miners, Alec, Elford, Jonathan, Perry, Nicky, Brady, Michael, Obeyesekera, Sharmin, Saunders, John, Taylor, Stephen, Gilleran, Gerry, Stretton, Cathy, Youssef, Elaney, Richardson, Celia, Roche, Mark, Stacey, David, Kirk, Sarah, Gompels, Mark, Jennings, Louise, Holder, Caroline, Baker, Katie-Anne, Robinson, Matthew, Street, Emma, Shomoye, Abayomi, Nwokolo, Nneka, Ogilvy, Ali, Mguni, Sfiso, Clark, Rebecca, Sajani, Cynthia, Espa, Veronica, Ladd, Sarah, Syred, Jonathan, Hamza, Lisa, Campbell, Lucy, Wandolo, Emily, Alagarajah, Janagan, Mashonganyika, Linda, Batham, Sally, Gilson, Richard, Trombin, Rita, Milinkovic, Ana, Oakland, Clare, Makoka, Nyasha, Wilson, Ruth, Green, Elizabeth, O'Connor, Sheila, Kempster, Sarah, Keating-Fedders, Katie, Ivens, Daniel, Tyrrell, Nicola, Rogers, Jemima, Belmondo, Silvia, Sohal, Manjit, Majewska, Wendy, Patterson, Anne, Okolo, Olanike, Cox, David, Tarik, Mariam, Jackson, Charlotte, Honigsbaum, Jeanette, Boggon, Clare, Ghosh, Simone, Kelly, Bernard, Aroney, Renee, Hand, James, Phiri, Elias, Partridge, Nick, Orton, Kay, Nardone, Anthony, Sullivan, Ann

“…ObjectiveTo assess the association of symptoms of depression and anxiety with sexual risk behaviour and history, among women and heterosexual men attending…”
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Correct recognition and management of anaphylaxis: not much change over a decade Autor Plumb, Benjamin, Bright, Philip, Gompels, Mark M, Unsworth, David Joe

“…Background Anaphylaxis is increasing in incidence. This potentially fatal condition requires immediate intramuscular adrenaline as a vital part of early…”
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Investigating pulmonary and non-infectious complications in common variable immunodeficiency disorders: a UK national multi-centre study Autor Bintalib, Heba M., Grigoriadou, Sofia, Patel, Smita Y., Mutlu, Leman, Sooriyakumar, Kavitha, Vaitla, Prashantha, McDermott, Elizabeth, Drewe, Elizabeth, Steele, Cathal, Ahuja, Manisha, Garcez, Tomaz, Gompels, Mark, Grammatikos, Alexandros, Herwadkar, Archana, Ayub, Rehana, Halliday, Neil, Burns, Siobhan O., Hurst, John R., Goddard, Sarah

“…Common Variable Immunodeficiency Disorders (CVID) encompass a spectrum of immunodeficiency characterised by recurrent infections and diverse non-infectious…”
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Peripheral Neuropathy in Virologically Suppressed People Living with HIV: Evidence from the PIVOT Trial Autor Schuldt, Anna L., Bern, Henry, Hart, Melanie, Gompels, Mark, Winston, Alan, Clarke, Amanda, Chen, Fabian, Stöhr, Wolfgang, Heslegrave, Amanda, Paton, Nicholas I., Petzold, Axel, Arenas-Pinto, Alejandro

“…The aim of this study is to identify the factors associated with peripheral neuropathy and to explore neurofilament light chain (NfL) as a biomarker for…”
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Trends in HIV testing in the UK primary care setting: a 15-year retrospective cohort study from 2000 to 2015 Autor Gompels, Mark, Michael, Skevi, Davies, Charlotte, Jones, Tim, Macleod, John, May, Margaret

“…ObjectivesTo estimate trends in HIV testing, positivity and prevalence in UK primary care for 2000–2015 as part of a wider investigation into reasons for late…”
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Chronic or recurrent Campylobacter enteritis in primary immunodeficiency: A UK national case-series and review of the literature Autor Grammatikos, Alexandros, Thomas, Moira, Johnston, Sarah, Moghaddas, Fiona, Albur, Mahableshwar, Yong, Patrick, Buckland, Matthew, Grigoriadou, Sofia, Whyte, Andrew F, Herwadkar, Archana, Gompels, Mark

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Chronic norovirus infection in immunodeficiency: A UK national case series Autor Grammatikos, Alexandros, Mangtani, Anisha, Ponsford, Mark, Jolles, Stephen, McDermott, Elizabeth, Johnston, Sarah, Frleta-Gilchrist, Marina, Yong, Patrick, Moghaddas, Fiona, Thomas, Moira, Patel, Smita, Blundell, Caitlin, Bright, Phil, Drewe, Elizabeth, Elcombe, Suzanne, Herwadkar, Archana, Murng, Sai, Kim, Da-In, Gompels, Mark, Lowe, David

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COVID-19 vaccine allergy advice and guidance: The experience of a UK tertiary referral centre Autor Moghaddas, Fiona, Tsiougkos, Nikolaos, Grammatikos, Alexandros, Bright, Philip D., Johnston, Sarah, Gompels, Mark

“…The objective was to review COVID-19 vaccine allergy advice and guidance requests received and assess the impact of advice outcome on vaccination outcome. A…”
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Benchmarked performance charts using principal components analysis to improve the effectiveness of feedback for audit data in HIV care Autor Michael, Skevi, Gompels, Mark, Sabin, Caroline, Curtis, Hilary, May, Margaret T.

“…Background Feedback tools for clinical audit data that compare site-specific results to average performance over all sites can be useful for quality…”
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False interpretation of diagnostic serology tests for patients treated with pooled human immunoglobulin G infusions: a trap for the unwary Autor Bright, Philip D, Smith, Lisa, Usher, Jane, Donati, Matthew, Johnston, Sarah L, Gompels, Mark M, Unsworth, D Joe

“…Therapeutic immunoglobulin G (IgG) products are produced from numerous plasma donations, and are infused in many medical conditions. The serological testing of…”
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Antibiotic prophylaxis for the prevention of respiratory tract infections in antibody deficient patients: A retrospective cohort study Autor Grammatikos, Alexandros, Albur, Mahableshwar, Gompels, Mark, Barnaby, Catherine Louise, Allan, Susan, Johnston, Sarah

“…•Antibiotic prophylaxis seems to be beneficial in antibody deficient patients.•The emergence of antimicrobial resistance did not seem to affect patient…”
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Protease inhibitor monotherapy for long-term management of HIV infection: a randomised, controlled, open-label, non-inferiority trial Autor Paton, Nicholas I, Stöhr, Wolfgang, Arenas-Pinto, Alejandro, Fisher, Martin, Williams, Ian, Johnson, Margaret, Orkin, Chloe, Chen, Fabian, Lee, Vincent, Winston, Alan, Gompels, Mark, Fox, Julie, Scott, Karen, Dunn, David T

“…Standard-of-care antiretroviral therapy (ART) uses a combination of drugs deemed essential to minimise treatment failure and drug resistance. Protease…”
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The Cost-Effectiveness of Early Access to HIV Services and Starting cART in the UK 1996–2008 Autor Beck, Eduard J., Mandalia, Sundhiya, Sangha, Roshni, Sharott, Peter, Youle, Mike, Baily, Guy, Brettle, Ray, Gompels, Mark, Johnson, Margaret, McCarron, Brendan, Ong, Ed, Pozniak, Anton, Schwenk, Achim, Taylor, Stephen, Walsh, John, Wilkins, Ed, Williams, Ian, Gazzard, Brian

“…To calculate use, cost and cost-effectiveness of people living with HIV (PLHIV) starting routine treatment and care before starting combination antiretroviral…”
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Lower Healthcare Costs Associated with the Use of a Single-Pill ARV Regimen in the UK, 2004–2008 Autor Beck, Eduard J., Mandalia, Sundhiya, Sangha, Roshni, Youle, Mike, Brettle, Ray, Gompels, Mark, Johnson, Margaret, Pozniak, Anton, Schwenk, Achim, Taylor, Stephen, Walsh, John, Wilkins, Ed, Williams, Ian, Gazzard, Brian

“…Investigate the cost and effects of a single-pill versus two- or three pill first-line antiretroviral combinations in reducing viral load, increasing CD4…”
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Clinically significant depressive symptoms and sexual behaviour among men who have sex with men Autor Miltz, Ada R., Rodger, Alison J., Sewell, Janey, Speakman, Andrew, Phillips, Andrew N., Sherr, Lorraine, Gilson, Richard J., Asboe, David, Nwokolo, Nneka C., Clarke, Amanda, Gompels, Mark M., Allan, Sris, Collins, Simon, Lampe, Fiona C.

“…The relationship between depression and sexual behaviour among men who have sex with men (MSM) is poorly understood. To investigate prevalence and correlates…”
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