Suchergebnisse - "Goetz, Laura H"

From precision interventions to precision health von Schork, Nicholas J., Goetz, Laura H.

“… Precision medicines, or those medicines that are tailored to individual genetic, molecular, physiologic, behavioral, and/or exposure profiles, are being …”
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Emerging therapeutic drug monitoring technologies: considerations and opportunities in precision medicine von Liang, Winnie S., Beaulieu-Jones, Brett, Smalley, Susan, Snyder, Michael, Goetz, Laura H., Schork, Nicholas J.

“… In recent years, the development of sensor and wearable technologies have led to their increased adoption in clinical and health monitoring settings. One area …”
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Assessing brain and biological aging trajectories associated with Alzheimer’s disease von Liang, Winnie S., Goetz, Laura H., Schork, Nicholas J.

“… The development of effective treatments to prevent and slow Alzheimer’s disease (AD) pathogenesis is needed in order to tackle the steady increase in the …”
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Personalized medicine: motivation, challenges, and progress von Goetz, Laura H, Schork, Nicholas J

“… There is a great deal of hype surrounding the concept of personalized medicine. Personalized medicine is rooted in the belief that since individuals possess …”
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Global health in general surgery residency: a national survey von Jayaraman, Sudha P, Ayzengart, Alexander L, Goetz, Laura H, Ozgediz, Doruk, Farmer, Diana L

“… Interest in global health during postgraduate training is increasing across disciplines. There are limited data from surgery residency programs on their …”
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Single-Subject Studies in Translational Nutrition Research von Schork, Nicholas J, Goetz, Laura H

“… There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of …”
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Strategies for Testing Intervention Matching Schemes in Cancer von Schork, Nicholas J, Goetz, Laura H, Lowey, James, Trent, Jeffrey

“… Personalized medicine, or the tailoring of health interventions to an individual's nuanced and often unique genetic, biochemical, physiological, behavioral, …”
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Genetic Support for Longevity-Enhancing Drug Targets: Issues, Preliminary Data, and Future Directions von McCorrison, Jamison, Girke, Thomas, Goetz, Laura H, Miller, Richard A, Schork, Nicholas J

“… Interventions meant to promote longevity and healthy aging have often been designed or observed to modulate very specific gene or protein targets. If there are …”
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Does Modulation of an Epigenetic Clock Define a Geroprotector? von Schork, Nicholas J, Beaulieu-Jones, Brett, Liang, Winnie, Smalley, Susan, Goetz, Laura H

“… There is growing interest in the development of interventions (e.g., drugs, diets, dietary supplements, behavioral therapies, etc.) that can enhance health …”
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The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank von Don, Janith, Schork, Andrew J., Glusman, Gwênlyn, Rappaport, Noa, Cummings, Steve R., Duggan, David, Raju, Anish, Hellberg, Kajsa-Lotta Georgii, Gunn, Sophia, Monti, Stefano, Perls, Thomas, Lapidus, Jodi, Goetz, Laura H., Sebastiani, Paola, Schork, Nicholas J.

“… Large-scale genome-wide association studies (GWAS) strongly suggest that most traits and diseases have a polygenic component. This observation has motivated …”
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Admixture and Clinical Phenotypic Variation von Goetz, Laura H., Uribe-Bruce, Liliana, Quarless, Danjuma, Libiger, Ondrej, Schork, Nicholas J.

“… All human populations exhibit some level of genetic differentiation. This differentiation, or population stratification, has many interacting sources, …”
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Management of recurrent rectal prolapse: surgical approach influences outcome von Steele, Scott R, Goetz, Laura H, Minami, Shigeki, Madoff, Robert D, Mellgren, Anders F, Parker, Susan C

“… Recurrent rectal prolapse is an unresolved problem and the optimal treatment is debated. This study was designed to review patterns of care and outcomes in a …”
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Overlapping sphincteroplasty: is it the standard of care? von Goetz, Laura H, Lowry, Ann C

“… Anal sphincter injury secondary to obstetric trauma during vaginal delivery occurs in nearly one of every five women. Episiotomy, forceps delivery, and …”
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Disagreement on foundational principles of biological aging von Gladyshev, Vadim N, Anderson, Benjamin, Barlit, Hanna, Barré, Benjamin, Beck, Samuel, Behrouz, Bahareh, Belsky, Daniel W, Chaix, Amandine, Chamoli, Manish, Chen, Brian H, Cheng, Kaiyang, Chuprin, Jane, Churchill, Gary A, Cipriano, Andrea, Colville, Alex, Deelen, Joris, Deigin, Yuri, Edmonds, KeHuan K, English, Bradley W, Fang, Ruogu, Florea, Michael, Gershteyn, Iosif M, Gill, Diljeet, Goetz, Laura H, Gorbunova, Vera, Griffin, Patrick T, Horvath, Steve, Borch Jensen, Martin, Jin, Xin, Jovanovska, Sara, Kajderowicz, Kathrin M, Kasahara, Tomoko, Kerepesi, Csaba, Kulkarni, Subhash, Labunskyy, Vyacheslav M, Levine, Morgan E, Libert, Sergiy, Lu, J Yuyang, Lu, Yuancheng Ryan, Marioni, Riccardo E, McCoy, Brianah M, Mitchell, Wayne, Moqri, Mahdi, Nasirian, Farzaneh, Niimi, Peter, Oh, Hamilton Se-Hwee, Okundaye, Brian, Parkhitko, Andrey A, Peshkin, Leonid, Petljak, Mia, Poganik, Jesse R, Pridham, Glen, Promislow, Daniel E L, Prusisz, Weronika, Quiniou, Margaux, Raj, Ken, Richard, Daniel, Ricon, Jose Luis, Rutledge, Jarod, Scheibye-Knudsen, Morten, Schork, Nicholas J, Seluanov, Andrei, Shadpour, Michael, Shindyapina, Anastasia V, Shuken, Steven R, Sivakumar, Sruthi, Stoeger, Thomas, Sugiura, Ayumu, Sutton, Nadia R, Suvorov, Alexander, Tarkhov, Andrei E, Teeling, Emma C, Trapp, Alexandre, Tyshkovskiy, Alexander, Unfried, Maximilian, Ward-Caviness, Cavin K, Yim, Sun Hee, Ying, Kejun, Yunes, Jeffrey, Zhang, Bohan, Zhavoronkov, Alex

“… Abstract To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting …”
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Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management von Talamonti, Mark S, Goetz, Laura H, Rao, Sambasiva, Joehl, Raymond J

“… This study was done to review the clinical presentation, surgical management, pathologic features, and prognostic factors for primary small-bowel cancers …”
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Sphincter⧸Perineal Reconstruction for Incontinence von Goetz, Laura H., Lowry, Ann C.

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