Search Results - "Gobinet, C."

Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy by Essendoubi, M., Gobinet, C., Reynaud, R., Angiboust, J. F., Manfait, M., Piot, O.

“…Background Topical delivery of molecules into the human skin is one of the main issues in dermatology and cosmetology. Several techniques were developed to…”
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Implementation of a classification strategy of Raman data collected in different clinical conditions: application to the diagnosis of chronic lymphocytic leukemia by Féré, M., Gobinet, C., Liu, L. H., Beljebbar, A., Untereiner, V., Gheldof, D., Chollat, M., Klossa, J., Chatelain, B., Piot, O.

“…The literature is rich in proof of concept studies demonstrating the potential of Raman spectroscopy for disease diagnosis. However, few studies are conducted…”
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Characterization of Type I and IV Collagens by Raman Microspectroscopy: Identification of Spectral Markers of the Dermo-Epidermal Junction by Piot, Olivier, -Pasco, S. Brassart, Feru, J., Gobinet, Cyril, Nguyen, T. T., Manfait, Michel

“…Type I and IV collagens are important constituents of the skin. Type I collagen is found in all dermal layers in high proportion, while type IV collagen is…”
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Conformation changes in human hair keratin observed using confocal Raman spectroscopy after active ingredient application by Essendoubi, M., Meunier, M., Scandolera, A., Gobinet, C., Manfait, M., Lambert, C., Auriol, D., Reynaud, R., Piot, O.

“…Objective In hair care cosmetic products’ evaluation, one commonly used method is to evaluate the hair appearance as a gold standard in order to determine the…”
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Diagnosis of hepatocellular carcinoma in cirrhotic patients: a proof-of-concept study using serum micro-Raman spectroscopy by Taleb, I, Thiéfin, G, Gobinet, C, Untereiner, V, Bernard-Chabert, B, Heurgué, A, Truntzer, C, Hillon, P, Manfait, M, Ducoroy, P, Sockalingum, G D

“…Hepatocellular carcinoma (HCC) is the third most common cause of cancer death worldwide. The development of novel diagnostic methods is needed to detect…”
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Preprocessing Methods of Raman Spectra for Source Extraction on Biomedical Samples: Application on Paraffin-Embedded Skin Biopsies by Gobinet, Cyril, Vrabie, Valeriu, Manfait, Michel, Piot, Olivier

“…Raman spectra are classically modeled as a linear mixing of spectra of molecular constituents of the analyzed sample. Source separation methods are thus well…”
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755 DIAGNOSIS OF HEPATOCELLLAR CARCINOMA IN CIRRHOTIC PATIENTS USING SERUM RAMAN MICROSPECTROSCOPY by Taleb, I., Sockalingum, G.D., Gobinet, C., Untereiner, V., Heurgué, A., Ducoroy, P., Hillon, P., Manfait, M., Thiéfin, G.

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Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin by Tfaili, Sana, Gobinet, Cyril, Josse, Gwendal, Angiboust, Jean-François, Manfait, Michel, Piot, Olivier

“…The present paper provides a spectral comparison between abdominal human skin (Transkin) and pig ear skin using confocal Raman microspectroscopy at 660 nm. Pig…”
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Prétraitements et méthodes de séparation de sources pour l’analyse des spectres Raman issus d’échantillons biologiques by Gobinet, C., Vrabie, V., Piot, O., Manfait, M.

“…La spectroscopie Raman est une technique efficace d’analyse de la composition moléculaire d’échantillons biologiques. Des méthodes de séparation de sources…”
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Focus on pre-processing step to ensure the clinical transferability of Raman data acquired on lymphocytes in different experimental and instrumental conditions by Féré, M., Piot, O., Liu, L.H, Beljebbar, A., Untereiner, V., Gheldof, D., Chollat, M., Klossa, J., Chatelain, B., Gobinet, C.

“…•Transferability of models.•Bench-to-bedside.•Pre-processing by EMSC allows multicentric data to be homogenized. The efficiency of Raman spectroscopy for the…”
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La biophotonique au service de l’identification de marqueurs pronostiques intracellulaires by Klossa, J., Daliphard, S., Troussard, X., Vielh, P., Manfait, M., Angulo, J., Flandrin, G., Beljebbar, A., Untereiner, V., Happillon, T., Gobinet, C., Velasco-Forero, S., Roux, S., Saada, V., Dagiral, R., Coomans, V., Froigneux, E., Rideau, P., Vievard, A.

“…Le projet vise à développer une solution d’imagerie hybride combinant en un même instrument microspectroscopie Raman et imagerie multispectrale pour le…”
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Automation of an algorithm based on fuzzy clustering for analyzing tumoral heterogeneity in human skin carcinoma tissue sections by Sebiskveradze, David, Vrabie, Valeriu, Gobinet, Cyril, Durlach, Anne, Bernard, Philippe, Ly, Elodie, Manfait, Michel, Jeannesson, Pierre, Piot, Olivier

“…This study aims to develop a new FT–IR spectral imaging of tumoral tissue permitting a better characterization of tumor heterogeneity and tumor/surrounding…”
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Raman imaging of single living cells: probing effects of non-cytotoxic doses of an anti-cancer drug by Draux, Florence, Gobinet, Cyril, Sulé-Suso, Josep, Manfait, Michel, Jeannesson, Pierre, Sockalingum, Ganesh D

“…Identifying cell response to a chemotherapy drug treatment, in particular at the single cell level, is an important issue in patient management. This study…”
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Infrared imaging as a cancer diagnostic tool: Introducing a new concept of spectral barcodes for identifying molecular changes in colon tumors by Nallala, Jayakrupakar, Piot, Olivier, Diebold, Marie‐Danièle, Gobinet, Cyril, Bouché, Olivier, Manfait, Michel, Sockalingum, Ganesh D.

“…Complementary diagnostic methods to conventional histopathology are under scrutiny for various types of cancers for rapid and molecular level diagnostics. In…”
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Bile analysis using high-throughput FTIR spectroscopy for the diagnosis of malignant biliary strictures: a pilot study in 57 patients by Untereiner, Valérie, Dhruvananda Sockalingum, Ganesh, Garnotel, Roselyne, Gobinet, Cyril, Ramaholimihaso, Fidy, Ehrhard, Florent, Diebold, Marie-Danièle, Thiéfin, Gérard

“…This study aimed at determining whether FTIR spectroscopy is able to distinguish bile samples from patients with and without malignant biliary strictures. Bile…”
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IR spectral imaging of secreted mucus: a promising new tool for the histopathological recognition of human colonic adenocarcinomas by Travo, Adrian, Piot, Olivier, Wolthuis, Rolf, Gobinet, Cyril, Manfait, Michel, Bara, Jacques, Forgue-Lafitte, Marie-Elisabeth, Jeannesson, Pierre

“…Travo A, Piot O, Wolthuis R, Gobinet C, Manfait M, Bara J, Forgue‐Lafitte M‐E & Jeannesson P 
(2010) Histopathology 56, 921–931 IR spectral imaging of secreted…”
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Vibrational spectroscopies for the analysis of cutaneous permeation: experimental limiting factors identified in the case of caffeine penetration by Tfaili, Sana, Gobinet, Cyril, Josse, Gwendal, Angiboust, Jean-François, Baillet, Arlette, Manfait, Michel, Piot, Olivier

“…Caffeine is utilised as a reference for permeation studies in dermatology and cosmetology. The present work aimed to monitor the permeation of a caffeine…”
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Effects of digital dewaxing methods on K-means-clusterized IR images collected on formalin-fixed paraffin-embedded samples of skin carcinoma by Sebiskveradze, D., Gobinet, C., Ly, E., Manfait, M., Jeannesson, P., Herbin, M., Piot, O., Vrabie, V.

“…Mid-IR spectral imaging is an efficient method to analyze biological samples. Several research studies showed its potential to diagnose cancerous tissues…”
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La biophotonique au service de l'identification de marqueurs pronostiques intracellulaires by Klossa, Jacques, Daliphard, Sylvie, Toussard, Xavier, Veilh, Philippe, Manfait, Michel, Angulo, Jesus, Flandrin, Georges, Beljebbar, Abdelilah, Untereiner, Valérie, Happillon, Teddy, Gobinet, Cyril, Velasco-Forero, Santiago, Roux, S., Saada, Véronique, Dagiral, R., Coomans, V., Froigneux, E., Rideau, P., Vievard, A.

“…Using biophotonics techniques to retrieve prognostic intracellular signatures : IHMO project aims at developing a multimodal microscopy platform that includes…”
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La biophotonique au service de l'identification de marqueurs pronostiques intracellulaires: ANR TecSan Technologies pour la santé et l'autonomie by KLOSSA, J, DALIPHARD, S, GOBINET, C, VELASCO-FORERO, S, ROUX, S, SAADA, V, DAGIRAL, R, COOMANS, V, FROIGNEUX, E, RIDEAU', P, VIEVARD, A, TROUSSARD, X, VIELH, P, MANFAIT, M, ANGULO, J, FLANDRIN, G, BELJEBBAR, A, UNTEREINER, V, HAPPILLON, T

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