Suchergebnisse - "Gobbi, Claudio"

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis von Barro, Christian, Benkert, Pascal, Disanto, Giulio, Tsagkas, Charidimos, Amann, Michael, Naegelin, Yvonne, Leppert, David, Gobbi, Claudio, Granziera, Cristina, Yaldizli, Özgür, Michalak, Zuzanna, Wuerfel, Jens, Kappos, Ludwig, Parmar, Katrin, Kuhle, Jens

“… Neuro-axonal injury is a key factor in the development of permanent disability in multiple sclerosis. Neurofilament light chain in peripheral blood has …”
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Safety profile of erenumab, galcanezumab and fremanezumab in pregnancy and lactation: Analysis of the WHO pharmacovigilance database von Noseda, Roberta, Bedussi, Francesca, Gobbi, Claudio, Zecca, Chiara, Ceschi, Alessandro

“… To assess the safety profile of erenumab, galcanezumab and fremanezumab in pregnancy and lactation. Safety reports of suspected adverse drug reactions were …”
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Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis von Disanto, Giulio, Barro, Christian, Benkert, Pascal, Naegelin, Yvonne, Schädelin, Sabine, Giardiello, Antonella, Zecca, Chiara, Blennow, Kaj, Zetterberg, Henrik, Leppert, David, Kappos, Ludwig, Gobbi, Claudio, Kuhle, Jens, Kuhle, Jens, Lorscheider, Johannes, Yaldizli, Özgür, Derfuss, Tobias, Kappos, Ludwig, Disanto, Giulio, Zecca, Chiara, Gobbi, Claudio, Benkert, Pascal, Achtnichts, Lutz, Nedeltchev, Krassen, Kamm, Christian P, Salmen, Anke, Chan, Andrew, Lalive, Patrice H, Pot, Caroline, Schluep, Myriam, Granziera, Cristina, Du Pasquier, Renaud, Müller, Stefanie, Vehoff, Jochen

“… Objective Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in …”
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Effectiveness and safety of Rituximab in multiple sclerosis: an observational study from Southern Switzerland von Scotti, Barbara, Disanto, Giulio, Sacco, Rosaria, Guigli, Marilu’, Zecca, Chiara, Gobbi, Claudio

“… Despite positive results from phase II and observational studies, Rituximab (RTX) is not currently approved for multiple sclerosis (MS) treatment and can only …”
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Imaging of neuralgic amyotrophy in the acute phase von Ripellino, Paolo, Arányi, Zsuzsanna, Alfen, Nens, Ventura, Elisa, Peyer, Anne‐Kathrin, Cianfoni, Alessandro, Gobbi, Claudio, Pedrick, Emily, Sneag, Darryl Brett

“… Introduction/Aims Hourglass‐like constrictions (HGCs) occur in neuralgic amyotrophy (NA), but the earliest time at which they can be recognized by imaging is …”
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Clinic and genetic predictors in response to erenumab von Zecca, Chiara, Cargnin, Sarah, Schankin, Christoph, Giannantoni, Nadia Mariagrazia, Viana, Michele, Maraffi, Isabella, Riccitelli, Gianna Carla, Sihabdeen, Shairin, Terrazzino, Salvatore, Gobbi, Claudio

“… Background and purpose Erenumab (ERE) is the first anticalcitonin gene‐related peptide receptor monoclonal antibody approved for migraine prevention. A …”
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Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBase von Noseda, Roberta, Bedussi, Francesca, Gobbi, Claudio, Ceschi, Alessandro, Zecca, Chiara

“… Background Current evidence on the safety of calcitonin gene–related peptide antagonists (CGRP-A) in pregnancy for the treatment of both episodic and chronic …”
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Biometry extraction and probabilistic anatomical atlas of the anterior Visual Pathway using dedicated high-resolution 3-D MRI von Pravatà, Emanuele, Diociasi, Andrea, Navarra, Riccardo, Carmisciano, Luca, Sormani, Maria Pia, Roccatagliata, Luca, Chincarini, Andrea, Ossola, Alessandra, Cardia, Andrea, Cianfoni, Alessandro, Kaelin-Lang, Alain, Gobbi, Claudio, Zecca, Chiara

“… Anterior Visual Pathway (aVP) damage may be linked to diverse inflammatory, degenerative and/or vascular conditions. Currently however, a standardized …”
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Influence of CNS T2-focal lesions on cervical cord atrophy and disability in multiple sclerosis von Pravatà, Emanuele, Valsasina, Paola, Gobbi, Claudio, Zecca, Chiara, Riccitelli, Gianna C, Filippi, Massimo, Rocca, Maria A

“… Mechanisms associated with cervical spinal cord (CSC) and upper thoracic spinal cord (TSC) atrophy in multiple sclerosis (MS) are poorly understood. To assess …”
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Identification of Neuroregenerative Protein Networks von Silva Filho, Luiz Claudio Gobbi Da, Meira, Débora Dummer, Casotti, Matheus Correia, Altoé, Lorena Souza Castro, Zetum, Aléxia Stefani Siqueira, Campanharo, Camilly Victória, Guaitolini, Yasmin Moreto, Louro, Luana Santos, Santana, Gabriel Mendonça, Louro, Thomas Erik Santos, Braga, Raquel Furlani Rocon, Trabach, Raquel Silva dos Reis, Paula, Flávia de, Carvalho, Elizeu Fagundes de, Louro, Iúri Drumond

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Clinical and molecular features of patients with amyotrophic lateral sclerosis and SOD1 mutations: a monocentric study von Gagliardi, Delia, Ripellino, Paolo, Meneri, Megi, Del Bo, Roberto, Antognozzi, Sara, Comi, Giacomo Pietro, Gobbi, Claudio, Ratti, Antonia, Ticozzi, Nicola, Silani, Vincenzo, Ronchi, Dario, Corti, Stefania

“… was the first gene associated with both familial and sporadic forms of amyotrophic lateral sclerosis (ALS) and is the second most mutated gene in Caucasian ALS …”
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Subjective patient-reported versus objective adherence to subcutaneous interferon β-1a in multiple sclerosis using RebiSmart®: the CORE study von Zecca, Chiara, Disanto, Giulio, Mühl, Sarah, Gobbi, Claudio

“… Background Patient adherence to treatment is key to preventing the worsening of neurological disability in multiple sclerosis (MS). The RebiSmart® autoinjector …”
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Feelings of loneliness, COVID-19-specific-health anxiety and depressive symptoms during the first COVID-19 wave in Swiss persons with multiple sclerosis von Hoepner, Robert, Rodgers, Stephanie, Stegmayer, Katharina, Steinemann, Nina, Haag, Christina, Calabrese, Pasquale, Manjaly, Zina-Mary, Salmen, Anke, Kesselring, Jürg, Zecca, Chiara, Gobbi, Claudio, Puhan, Milo A., Walther, Sebastian, von Wyl, Viktor

“… The aim of our study was to investigate whether self-reported feeling of loneliness (FoL) and COVID-19-specific health anxiety were associated with the …”
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Alpha-synuclein oligomers and small nerve fiber pathology in skin are potential biomarkers of Parkinson’s disease von Vacchi, Elena, Senese, Camilla, Chiaro, Giacomo, Disanto, Giulio, Pinton, Sandra, Morandi, Sara, Bertaina, Ilaria, Bianco, Giovanni, Staedler, Claudio, Galati, Salvatore, Gobbi, Claudio, Kaelin-Lang, Alain, Melli, Giorgia

“… The proximity ligation assay (PLA) is a specific and sensitive technique for the detection of αSyn oligomers (αSyn-PLA), early and toxic species implicated in …”
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Amyloid detection and typing yield of skin biopsy in systemic amyloidosis and polyneuropathy von Pinton, Sandra, Vacchi, Elena, Chiaro, Giacomo, Raimondi, Andrea, Tzankov, Alexandar, Gerber, Bernhard, Gobbi, Claudio, Kaelin‐Lang, Alain, Melli, Giorgia

“… Objective Disease‐modifying therapies are available for amyloidosis but are ineffective if end‐organ damage is severe. As small fiber neuropathy is an early …”
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MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial von Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, Hoepner, Robert, Disanto, Giulio, Gobbi, Claudio, Rooshenas, Leila, Schwenkglenks, Matthias, Lambiris, Mark J., Kappos, Ludwig, Kuhle, Jens, Yaldizli, Özgür, Hemkens, Lars G.

“… Background Treatment decisions for persons with relapsing–remitting multiple sclerosis (RRMS) rely on clinical and radiological disease activity, the …”
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Narrative Review on the Use of Cladribine Tablets as Exit Therapy for Stable Elderly Patients with Multiple Sclerosis von de Seze, Jerome, Dive, Dominique, Ayrignac, Xavier, Castelnovo, Giovanni, Payet, Marianne, Rayah, Amel, Gobbi, Claudio, Vermersch, Patrick, Zecca, Chiara

“… The number of ageing people with relapsing multiple sclerosis (RMS) is increasing. The efficacy of disease-modifying therapies (DMTs) for RMS declines with …”
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Tau seeding activity in skin biopsy differentiates tauopathies from synucleinopathies von Dellarole, Ilaria Linda, Vacchi, Elena, Ruiz-Barrio, Inigo, Pinton, Sandra, Raimondi, Andrea, Rossi, Stefania, Morandi, Sara, Bianco, Giovanni, Begum Bacinoglu, Merve, Lombardo, Annalisa, Celauro, Luigi, Staedler, Claudio, Galati, Salvatore, Pagonabarraga, Javier, Kulisevsky, Jaime, Legname, Giuseppe, Gobbi, Claudio, Kaelin-Lang, Alain, Moda, Fabio, Melli, Giorgia

“… Most neurodegenerative diseases lack definitive diagnostic tests, and the identification of easily accessible and reliable biomarkers remains a critical unmet …”
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Use of glatiramer acetate between 2010–2015: effectiveness, safety and reasons to start GA as first or second line treatment in Swiss multiple sclerosis patients von Zecca, Chiara, Disanto, Giulio, Sacco, Rosaria, Riccitelli, Gianna C., Gobbi, Claudio

“… Background Glatiramer acetate (GA) is one of the first therapies approved for multiple sclerosis (MS). We prospectively included and monitored drug-naïve and …”
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Real-world use of disease-modifying therapy in persons with multiple sclerosis aged 55 and over von Stanikić, Mina, Salmen, Anke, Kamm, Christian P, Roth, Patrick, Calabrese, Pasquale, Zecca, Chiara, Gobbi, Claudio, Baum, Claudia, Ineichen, Benjamin Victor, von Wyl, Viktor, Stanikic, Mina, Salmen, Anke, Kamm, Christian P, Roth, Patrick, Calabrese, Pasquale, Zecca, Chiara, Gobbi, Claudio, Baum, Claudia, Ineichen, Benjamin Victor, Wyl, Viktor von

“… BackgroundAs the average age of multiple sclerosis (MS) population rises globally, unclear guidelines on disease-modifying therapy (DMT) use in older persons …”
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