Výsledky vyhľadávania - "Giunchi, Francesca"

Perineural Invasion and Risk of Lethal Prostate Cancer Autor Zareba, Piotr, Flavin, Richard, Isikbay, Masis, Rider, Jennifer R, Gerke, Travis A, Finn, Stephen, Pettersson, Andreas, Giunchi, Francesca, Unger, Robert H, Tinianow, Alex M, Andersson, Swen-Olof, Andrén, Ove, Fall, Katja, Fiorentino, Michelangelo, Mucci, Lorelei A

“…Prostate cancer has a propensity to invade and grow along nerves, a phenomenon called perineural invasion (PNI). Recent studies suggest that the presence of…”
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High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program Autor Labbé, David P., Zadra, Giorgia, Yang, Meng, Reyes, Jaime M., Lin, Charles Y., Cacciatore, Stefano, Ebot, Ericka M., Creech, Amanda L., Giunchi, Francesca, Fiorentino, Michelangelo, Elfandy, Habiba, Syamala, Sudeepa, Karoly, Edward D., Alshalalfa, Mohammed, Erho, Nicholas, Ross, Ashley, Schaeffer, Edward M., Gibb, Ewan A., Takhar, Mandeep, Den, Robert B., Lehrer, Jonathan, Karnes, R. Jeffrey, Freedland, Stephen J., Davicioni, Elai, Spratt, Daniel E., Ellis, Leigh, Jaffe, Jacob D., DʼAmico, Anthony V., Kantoff, Philip W., Bradner, James E., Mucci, Lorelei A., Chavarro, Jorge E., Loda, Massimo, Brown, Myles

“…Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression…”
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Status of Programmed Death Ligand 1 (PD-L1) by Immunohistochemistry and Scoring Algorithms Autor Giunchi, Francesca, Gevaert, Thomas, Scarpelli, Marina, Fiorentino, Michelangelo

“…The detection of the Programmed Death Ligand 1 (PD-L1) protein by immunohistochemistry is currently the only approved test predictive of response to drugs…”
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Prostate cancer heterogeneity: Discovering novel molecular targets for therapy Autor Ciccarese, Chiara, Massari, Francesco, Iacovelli, Roberto, Fiorentino, Michelangelo, Montironi, Rodolfo, Di Nunno, Vincenzo, Giunchi, Francesca, Brunelli, Matteo, Tortora, Giampaolo

“…•Prostate cancer (PCa) shows a broad spectrum of biological and clinical behavior, which represents the epiphenomenon of an extreme genetic heterogeneity.•The…”
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Current Strategies and Novel Therapeutic Approaches for Metastatic Urothelial Carcinoma Autor Mollica, Veronica, Rizzo, Alessandro, Montironi, Rodolfo, Cheng, Liang, Giunchi, Francesca, Schiavina, Riccardo, Santoni, Matteo, Fiorentino, Michelangelo, Lopez-Beltran, Antonio, Brunocilla, Eugenio, Brandi, Giovanni, Massari, Francesco

“…Urothelial carcinoma (UC) is a frequent cause of cancer-related deaths worldwide. Metastatic UC has been historically associated with poor prognosis, with a…”
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Interchangeability of light and virtual microscopy for histopathological evaluation of prostate cancer Autor Zelic, Renata, Giunchi, Francesca, Lianas, Luca, Mascia, Cecilia, Zanetti, Gianluigi, Andrén, Ove, Fridfeldt, Jonna, Carlsson, Jessica, Davidsson, Sabina, Molinaro, Luca, Vincent, Per Henrik, Richiardi, Lorenzo, Akre, Olof, Fiorentino, Michelangelo, Pettersson, Andreas

“…Virtual microscopy (VM) holds promise to reduce subjectivity as well as intra- and inter-observer variability for the histopathological evaluation of prostate…”
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Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer Autor Tyekucheva, Svitlana, Bowden, Michaela, Bango, Clyde, Giunchi, Francesca, Huang, Ying, Zhou, Chensheng, Bondi, Arrigo, Lis, Rosina, Van Hemelrijck, Mieke, Andrén, Ove, Andersson, Sven-Olof, Watson, R. William, Pennington, Stephen, Finn, Stephen P., Martin, Neil E., Stampfer, Meir J., Parmigiani, Giovanni, Penney, Kathryn L., Fiorentino, Michelangelo, Mucci, Lorelei A., Loda, Massimo

“…While progression from normal prostatic epithelium to invasive cancer is driven by molecular alterations, tumor cells and cells in the cancer microenvironment…”
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Is There a Role for Immunotherapy in Prostate Cancer? Autor Rizzo, Alessandro, Mollica, Veronica, Cimadamore, Alessia, Santoni, Matteo, Scarpelli, Marina, Giunchi, Francesca, Cheng, Liang, Lopez-Beltran, Antonio, Fiorentino, Michelangelo, Montironi, Rodolfo, Massari, Francesco

“…In the last decade, immunotherapy has revolutionized the treatment landscape of several hematological and solid malignancies, reporting unprecedented response…”
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An open-source platform for structured annotation and computational workflows in digital pathology research Autor Lianas, Luca, Del Rio, Mauro, Pireddu, Luca, Aspegren, Oskar, Giunchi, Francesca, Fiorentino, Michelangelo, Leo, Simone, Zelic, Renata, Vincent, Per Henrik, Destefanis, Nicolas, Zugna, Daniela, Richiardi, Lorenzo, Pettersson, Andreas, Akre, Olof, Frexia, Francesca

“…The rapid evolution of digital pathology has enabled large-scale data acquisition, driving sophisticated clinical research and advancing the development of…”
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Validation of the immunohistochemical expression of programmed death ligand 1 (PD-L1) on cytological smears in advanced non small cell lung cancer Autor Capizzi, Elisa, Ricci, Costantino, Giunchi, Francesca, Zagnoni, Stefano, Ceccarelli, Claudio, Gómez, Begoña Urrios Álvarez, Casolari, Laura, Gelsomino, Francesco, Trisolini, Rocco, Fiorentino, Michelangelo, Ardizzoni, Andrea

“…•Currently, only FFPE samples are acceptable for the IHC assessment of PD-L1 in NSCLC.•Cytological smears are the only available material for a subset of…”
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[18F]-Fluciclovine PET/CT for preoperative nodal staging in high-risk primary prostate cancer: final results of a prospective trial Autor Zanoni, Lucia, Bianchi, Lorenzo, Nanni, Cristina, Pultrone, Cristian, Giunchi, Francesca, Bossert, Irene, Matti, Antonella, Schiavina, Riccardo, Fiorentino, Michelangelo, Romagnoli, Daniele, Fonti, Cristina, Lodi, Filippo, D’Errico, Antonietta, Brunocilla, Eugenio, Porreca, Angelo, Fanti, Stefano

“…Purpose The conventional imaging flowchart for prostate cancer (PCa) staging may fail in correctly detecting lymph node metastases (LNM). Pelvic lymph node…”
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Low level of interobserver concordance in assessing histological subtype and tumor grade in patients with penile cancer may impair patient care Autor Dorofte, Luiza, Grélaud, Diane, Fiorentino, Michelangelo, Giunchi, Francesca, Ricci, Costantino, Franceschini, Tania, Riefolo, Mattia, Davidsson, Sabina, Carlsson, Jessica, Lillsunde Larsson, Gabriella, Karlsson, Mats G.

“…Differentiation between penile squamous cell carcinoma patients who can benefit from limited organ-sparing surgery and those at significant risk of lymph node…”
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PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD) Autor Angelicola, Stefania, Giunchi, Francesca, Ruzzi, Francesca, Frascino, Mariateresa, Pitzalis, Mary, Scalambra, Laura, Semprini, Maria Sofia, Pittino, Olga Maria, Cappello, Chiara, Siracusa, Irene, Chillico, Ilaria Candida, Di Noia, Martina, Turato, Cristian, De Siervi, Silvia, Lescai, Francesco, Ciavattini, Teresa, Lopatriello, Giulia, Bertoli, Luca, De Jonge, Hugo, Iamele, Luisa, Altimari, Annalisa, Gruppioni, Elisa, Ardizzoni, Andrea, Rossato, Marzia, Gelsomino, Francesco, Lollini, Pier-Luigi, Palladini, Arianna

“…Background Non-Small Cell Lung Cancer (NSCLC) is the leading cause of cancer death worldwide. Although immune checkpoint inhibitors (ICIs) have shown…”
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Immunohistochemistry analysis of PSMA expression at prostatic biopsy in high-risk prostate cancer: potential implications for PSMA-PET patient selection Autor Droghetti, Matteo, Bianchi, Lorenzo, Presutti, Massimiliano, Vetrone, Luigia, Farolfi, Andrea, Mei, Riccardo, Giunchi, Francesca, Degiovanni, Alessio, Mottaran, Angelo, Piazza, Pietro, Cangemi, Danilo, Castellucci, Paolo, D’Errico, Antonietta, Schiavina, Riccardo, Brunocilla, Eugenio, Fanti, Stefano

“…Prostate-specific membrane antigen (PSMA) is a transmembrane protein expressed by normal prostatic tissue. Therefore, molecular imaging targeting PSMA…”
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Multiparametric magnetic resonance imaging for the differential diagnosis between granulomatous prostatitis and prostate cancer: a literature review to an intriguing diagnostic challenge Autor Gaudiano, Caterina, Renzetti, Benedetta, De Fino, Cristina, Corcioni, Beniamino, Ciccarese, Federica, Bianchi, Lorenzo, Schiavina, Riccardo, Droghetti, Matteo, Giunchi, Francesca, Brunocilla, Eugenio, Fiorentino, Michelangelo

“…Multiparametric magnetic resonance imaging (mpMRI) is currently the most effective diagnostic tool for detecting prostate cancer (PCa) and evaluating…”
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The impact of multiparametric MRI features to identify the presence of prevalent cribriform pattern in the peripheral zone tumors Autor Gaudiano, Caterina, Bianchi, Lorenzo, De Cinque, Antonio, Corcioni, Beniamino, Giunchi, Francesca, Schiavina, Riccardo, Fiorentino, Michelangelo, Brunocilla, Eugenio, Golfieri, Rita

“…Purpose To assess the role of the multiparametric Magnetic Resonance Imaging (mpMRI) in predicting the cribriform pattern in both the peripheral and transition…”
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Infiltration of M2 Macrophages and Regulatory T Cells Plays a Role in Recurrence of Renal Cell Carcinoma Autor Davidsson, Sabina, Fiorentino, Michelangelo, Giunchi, Francesca, Eriksson, Margareta, Erlandsson, Ann, Sundqvist, Pernilla, Carlsson, Jessica

“…It has been hypothesized that M2 macrophages and regulatory T cells (Tregs) may contribute to tumor progression by suppression of antitumor immunity. To…”
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[68Ga]Ga-FAPI-46 PET/CT for Staging Suspected/Confirmed Lung Cancer: Results on the Surgical Cohort Within a Monocentric Prospective Trial Autor Zanoni, Lucia, Fortunati, Emilia, Cuzzani, Giulia, Malizia, Claudio, Lodi, Filippo, Cabitza, Veronica Serena, Brusa, Irene, Emiliani, Stefano, Assenza, Marta, Antonacci, Filippo, Giunchi, Francesca, Degiovanni, Alessio, Ferrari, Marco, Natali, Filippo, Galasso, Thomas, Bandelli, Gian Piero, Civollani, Simona, Candoli, Piero, D’Errico, Antonietta, Solli, Piergiorgio, Fanti, Stefano, Nanni, Cristina

“…Background/Objectives. To evaluate T&N-staging diagnostic performance of [68Ga]Ga-FAPI-46 PET/CT (FAPI) in a suspected/confirmed lung cancer surgical cohort…”
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Storage Time and DNA Quality Determine BRCA1/2 Sequencing Success in Prostate Cancer: A Multicentre Analysis with Therapeutic Implications Autor Vescovo, Mariavittoria, Raspollini, Maria Rosaria, Nibid, Lorenzo, Castiglione, Francesca, Nardi, Eleonora, de Biase, Dario, Massari, Francesco, Giunchi, Francesca, Pepe, Francesco, Troncone, Giancarlo, Malapelle, Umberto, Carosi, Mariantonia, Casini, Beatrice, Melucci, Elisa, Fassan, Matteo, Toffolatti, Luisa, Guerini-Rocco, Elena, Conversano, Federica, Rappa, Alessandra, Tommasi, Stefania, Coppola, Claudio Antonio, Zeppa, Pio, Caputo, Alessandro, Gaeta, Sara, Pagni, Fabio, Seminati, Davide, Vecchione, Andrea, Scarpino, Stefania, Righi, Daniela, Taffon, Chiara, Prata, Francesco, Perrone, Giuseppe

“…Background: Approximately 25.0% of metastatic prostate cancer patients harbour DNA damage repair mutations, including BRCA1 and BRCA2, which are actionable…”
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Reliability of programmed death ligand 1 (PD-L1) tumor proportion score (TPS) on cytological smears in advanced non-small cell lung cancer: a prospective validation study Autor Ricci, Costantino, Capizzi, Elisa, Giunchi, Francesca, Casolari, Laura, Gelsomino, Francesco, Rihawi, Karim, Natali, Filippo, Livi, Vanina, Trisolini, Rocco, Fiorentino, Michelangelo, Ardizzoni, Andrea

“…Introduction: Programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) assessment is mandatory for the single agent pembrolizumab treatment of patients…”
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