Výsledky vyhľadávania - "Ghazouani, Lakhdar"

Toxic effect of alpha cypermethrin, an environmental pollutant, on myocardial tissue in male wistar rats Autor Ghazouani, Lakhdar, Feriani, Anouar, Mufti, Afoua, Tir, Meriam, Baaziz, Intissar, Mansour, Hedi Ben, Mnafgui, Kais

“…α-Cypermethrin (CYP) is a pyrethroid insecticide-like environmental pollutant, widely found in the environment. New research links exposure to high levels of…”
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Oleuropein Protects Against Cerebral Ischemia Injury in Rats: Molecular Docking, Biochemical and Histological Findings Autor Mnafgui, Kais, Ghazouani, Lakhdar, Hajji, Raouf, Tlili, Abir, Derbali, Fatma, da Silva, Francisco Ivan, Araújo, Joabe Lima, de Oliveira Schinoff, Bianca, Bachega, José Fernando Ruggiero, da Silva Santos, Antônia Laíres, Allouche, Noureddine

“…This study was designed to evaluate the underlying protective mechanisms of oleuropein involved in alleviating brain damage in a rat model of ischemic stroke…”
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Bifenthrin exerts proatherogenic effects via arterial accumulation of native and oxidized LDL in rats: the beneficial role of vitamin E and selenium Autor Feriani, Anouar, Hachani, Rafik, Tir, Meriam, Ghazouani, Lakhdar, Mufti, Afoua, Borgi, Mohamed Ali, Allagui, Mohamed Salah

“…The purpose of this study was to investigate, for the first time, the effects of Bifenthrin (Bif) chronic exposure on plasmatic and aortic lipid parameters…”
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Potential Hepatoprotective Activity of Super Critical Carbon Dioxide Olive Leaf Extracts against CCl4-Induced Liver Damage Autor Taamalli, Amani, Feriani, Anouar, Lozano-Sanchez, Jesús, Ghazouani, Lakhdar, El Mufti, Afoua, Allagui, Mohamed Salah, Segura-Carretero, Antonio, Mhamdi, Ridha, Arráez-Roman, David

“…Virgin olive oil has demonstrated its effective activity against oxidative stress. However, data on the bioactive effect of olive leaves or their major…”
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Structural Characterization and Cardioprotective Effect of Water-Soluble Polysaccharides Extracted from Clematis flammula Autor Baaziz, Intissar, Ghazouani, Lakhdar, Rjeibi, Ilhem, Feriani, Anouar, Mnafgui, Kais, Mufti, Afoua, Traikia, Mounir, Le Cerf, Didier, Michaud, Philippe, Pierre, Guillaume, Cherif, Slim

“…Clematis flammula is widely used for its pharmacological properties in Tunisia. This work aimed to explore, in a rat model, the cardiopreventive capacity of…”
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174G>C interleukin-6 gene polymorphism in Tunisian patients with coronary artery disease Autor Ghazouani, Lakhdar, Abboud, Nesrine, Khalifa, Sonia Ben Hadj, Added, Faouzi, Khalfallah, Ali Ben, Nsiri, Brahim, Mediouni, Mounira, Mahjoub, Touhami

“…A state of low-grade inflammation accompanies the pathogenesis of atherosclerotic events. Interleukin-6 (IL-6) is a pleotropic pro-inflammatory cytokine that…”
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A novel synthetised sulphonylhydrazone coumarin (E)‐4‐methyl‐N′‐(1‐(3‐oxo‐3H‐benzo[f]chromen‐2‐ yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol‐induced myocardial infarction in rats by attenuating oxidative damage, biological changes and electrocardiogram Autor Ghazouani, Lakhdar, Khdhiri, Emna, Elmufti, Afoua, Zarei, Armin, Feriani, Anouar, Baaziz, Intissar, Hajji, Raouf, Abid, Majdi, Ammar, Houcine, Abid, Souhir, Allouche, Noureddine, Mnafgui, Kais, Ramazani, Ali, Tlili, Nizar

“…Coumarins and their derivatives are becoming a potential source for new drug discovery due to their vast array of biological activities. The present study was…”
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(E)-N’-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests Autor Khdhiri, Emna, Mnafgui, Kais, Ghazouani, Lakhdar, Feriani, Anouar, Hajji, Raouf, Bouzanna, Walid, Allouche, Noureddine, Bazureau, Jean-Pierre, Ammar, Houcine, Abid, Souhir

“…The current study was aimed to assess the protective effect of a new molecule (E)-N’-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide, denoted 1c,…”
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HPLC-DAD-ESI-QTOF-MS/MS profiling of Zygophyllum album roots extract and assessment of its cardioprotective effect against deltamethrin-induced myocardial injuries in rat, by suppression of oxidative stress-related inflammation and apoptosis via NF-κB signaling pathway Autor Feriani, Anouar, Tir, Meriam, Gómez-Caravaca, Ana María, Contreras, María del Mar, Talhaoui, Nassima, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, Allagui, Mohamed Salah

“…Zygophyllum album is widely used to treat many cardiovascular diseases (CVDs) and as anti-inflammatory plant. This study aimed to investigate the mechanism of…”
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Anti-embolic and anti-oxidative effects of a novel (E)-4-amino-N′-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl) ethylidene) benzohydrazide against isoproterenol and vitamin-K induced ischemic stroke Autor Mnafgui, Kais, Khdhiri, Emna, Ghazouani, Lakhdar, Ncir, Marwa, Zaafouri, Zouhaier, Allouche, Noureddine, Elfeki, Abdelfattah, Ammar, Houcine, Abid, Souhir, Hajji, Raouf

“…This study aimed to evaluate the cerebroprotective potential of a novel synthetic coumarin, (E)-4-amino-N′-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl)ethylidene)…”
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Plasticizers and bisphenol A, in packaged foods sold in the Tunisian markets: study of their acute in vivo toxicity and their environmental fate Autor Beltifa, Asma, Feriani, Anouar, Machreki, Monia, Ghorbel, Asma, Ghazouani, Lakhdar, Di Bella, Giuseppa, Van Loco, Joris, Reyns, Tim, Mansour, Hedi Ben

“…Today, processed and packaged foods are considered as among the major sources of human exposure to plasticizers and bisphenol which migrate from plastic…”
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Cardioprotective effects of ( E )-4-hydroxy-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide: a newly synthesized coumarin hydrazone against isoproterenol-induced myocardial infarction in a rat model Autor Ghazouani, Lakhdar, Khdhiri, Emna, Elmufti, Afoua, Feriani, Anouar, Tir, Meriam, Baaziz, Intissar, Hajji, Raouf, Ben Mansour, Hedi, Ammar, Houcine, Abid, Souhir, Mnafgui, Kais

“…The current study was carried out to evaluate the effect of pretreatment and co-treatment with a newly synthesized coumarin hydrazone, (…”
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Cardiopreventive capacity of a novel (E)‐Nʹ‐(1‐(7‐methoxy‐2‐oxo‐2H‐chromen‐3‐yl) ethylidene)‐4‐methylbenzenesulfonohydrazide against isoproterenol‐induced myocardial infarction by moderating biochemical, oxidative stress, and histological parameters Autor Khdhiri, Emna, Mnafgui, Kais, Ncir, Marwa, Feriani, Anouar, Ghazouani, Lakhdar, Hajji, Raouf, Jallouli, Dana, Abid, Majdi, Jamoussi, Kamel, Allouche, Noureddine, Ammar, Houcine, Abid, Souhir

“…This study is carried out to assess the cardiopreventive effect of (E)‐N’‐(1‐(7‐methoxy‐2‐oxo‐2H‐chromen‐3‐yl) ethylidene)‐4‐methylbenzenesulfonohydrazide or…”
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(E)-N′-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis Autor Ghazouani, Lakhdar, Mnafgui, Kais, Abid, Souhir, Ammar, Houcine, Hajji, Raouf, Tlili, Nizar, Elmufti, Afoua, Tir, Meriam, Khdhiri, Emna, Feryeni, Anwar, Allouche, Noureddine

“…The present study was directed to investigate the effect of precotreatment with (E)-N′-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl) ethylidene) benzohydrazide…”
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Phytochemical Profiling of Ephedra alata subsp. alenda Seeds by High-Performance Liquid Chromatography-Electrospray Ionization-Quadrupole-Time-of-Flight-Mass Spectrometry (HPLC-ESI-QTOF-MS), Molecular Docking, and Antioxidant, Anti-diabetic, and Acetylcholinesterase Inhibition Autor Mufti, Afoua, Tir, Meriam, Zarei, Armin, Contreras, María del Mar, Gómez-Cruz, Irene, Feriani, Anouar, Ghazouani, Lakhdar, Saadaoui, Ezzeddine, Allagui, Mohamed Salah, Harrath, Abdel Halim, Ramazani, Ali, Tlili, Nizar

“…The aim of the current work was to study for the first time the phytochemical profile of Ephedra alata subsp. alenda seeds extract (ESS). The extract was…”
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Zygophyllum album saponins prevent atherogenic effect induced by deltamethrin via attenuating arterial accumulation of native and oxidized LDL in rats Autor Feriani, Anouar, Tir, Meriam, Hachani, Rafik, Gómez-Caravaca, Ana María, Contreras, María del Mar, Taamalli, Amani, Talhaoui, Nassima, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, El Feki, Abdelfattah, Harrath, Abdel Halim, Allagui, Mohamed Salah

“…The current study aimed to examine, for the first time, the relationship between exposure to deltamethrin (DLM) and atherogenic lipid profile disorders in…”
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Contribution of adiponectin polymorphisms to the risk of coronary artery disease in a North‐African Tunisian population Autor Ghazouani, Lakhdar, Elmufti, Afoua, Baaziz, Intissar, Chaabane, Ibtissem, Ben Mansour, Hedi

“…Background Adiponectin, an adipocyte‐derived protein, is known to play a key role in the processes leading to atherosclerosis and coronary artery disease (CAD)…”
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Zygophyllum album leaves extract prevented hepatic fibrosis in rats, by reducing liver injury and suppressing oxidative stress, inflammation, apoptosis and the TGF-β1/Smads signaling pathways. Exploring of bioactive compounds using HPLC–DAD–ESI–QTOF-MS/MS Autor Feriani, Anouar, Tir, Meriam, Gómez-Caravaca, Ana María, del Mar Contreras, María, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, El Feki, Abdelfattah, Harrath, Abdel Halim, Allagui, Mohamed Salah

“…Zygophyllum album is traditionally used against many illnesses, such as liver disease. The present study investigated the bioactive compounds in methanol…”
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Persistent plasticizers and bisphenol in the cheese of Tunisian markets induced biochemical and histopathological alterations in male BALB/c mice Autor Beltifa, Asma, Feriani, Anouar, Macherki, Monia, Ghorbel, Asma, Ghazouani, Lakhdar, Di Bella, Giuseppa, Sire, Olivier, Van Loco, Joris, Reyns, Tim, Mansour, Hedi Ben

“…Clinical evidences, experimental models, and epidemiology of many studies suggest that phthalate-based plasticizers , aliphatic ester , and bisphenol A (BPA)…”
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Protective effect of Globularia alypum leaves against deltamethrin-induced nephrotoxicity in rats and determination of its bioactive compounds using high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole–time-of-flight mass spectrometry Autor Feriani, Anouar, del Mar Contreras, María, Talhaoui, Nassima, Gómez-Caravaca, Ana María, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, El Feki, Abdelfatteh, Allagui, Mohamed Salah

“…•RP-HPLC-DAD-ESI-QTOF-MS/MS analysis of Globularia alypum extract was performed.•Thirty-nine compounds were identified and quantified.•Protective effect of G…”
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