Výsledky vyhľadávania - "Genetic Engineering - methods"

A critical analysis of codon optimization in human therapeutics Autor Mauro, Vincent P., Chappell, Stephen A.

“… We critically review this subject, identifying additional potential hazards including some unique to nucleic acid therapies…”
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Engineering Saccharomyces boulardii for Probiotic Supplementation of l‐Ergothioneine Autor Tang, Chaoqun, Zhang, Lu, Wang, Junyi, Zou, Congjia, Zhang, Yalin, Yuan, Jifeng

“… Due to its unique antimicrobial and immune‐regulating functions, it has become a significant subject of research in the field of probiotics…”
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A genetically encoded photoactivatable Rac controls the motility of living cells Autor Wu, Yi I., Frey, Daniel, Lungu, Oana I., Jaehrig, Angelika, Schlichting, Ilme, Kuhlman, Brian, Hahn, Klaus M.

“…A light touch on proteins Many aspects of cellular function depend on when and where in the cell various protein activities are turned 'on' or 'off' at the…”
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Bottom-up synthetic immunology Autor Göpfrich, Kerstin, Platten, Michael, Frischknecht, Friedrich, Fackler, Oliver T.

“… However, genetic immune engineering is mostly limited to ex vivo applications and is subject to complex counter-regulation inherent to immune functions…”
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Genome editing of crops: A renewed opportunity for food security Autor Georges, Fawzy, Ray, Heather

“…Genome editing of crop plants is a rapidly advancing technology whereby targeted mutations can be introduced into a plant genome in a highly specific manner…”
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Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges Autor Turan, Soeren, Galla, Melanie, Ernst, Ellen, Qiao, Junhua, Voelkel, Christine, Schiedlmeier, Bernhard, Zehe, Christoph, Bode, Juergen

“…Traditional DNA transduction routes used for the modification of cellular genomes are subject to unpredictable alterations, as the cell-intrinsic repair machinery may affect both the integrity…”
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Artificial gametes: a systematic review of biological progress towards clinical application Autor Hendriks, Saskia, Dancet, Eline A F, van Pelt, Ans M M, Hamer, Geert, Repping, Sjoerd

“… The electronic database 'Medline/Pubmed' was systematically searched with medical subject heading (MesH…”
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Engineering the lodging resistance mechanism of post-Green Revolution rice to meet future demands Autor HIRANO, Ko, ORDONIO, Reynante Lacsamana, MATSUOKA, Makoto

“… This is because relying solely on the semi-dwarf trait is subject to certain limitations, making it necessary to use other important traits to reinforce…”
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Engineered T cells for cancer therapy Autor June, Carl H., Maus, Marcela V., Plesa, Gabriela, Johnson, Laura A., Zhao, Yangbing, Levine, Bruce L., Grupp, Stephan A., Porter, David L.

“… functionalities, is the subject of this focused research review…”
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Engineering and expressing circular RNAs via tRNA splicing Autor Noto, John J., Schmidt, Casey A., Matera, A. Gregory

“…Circular (circ)RNAs have recently become a subject of great biologic interest. It is now clear that they represent a diverse and abundant class of RNAs with regulated expression and evolutionarily conserved functions…”
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Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell‐Derived Microglia Autor Haenseler, Walther, Rajendran, Lawrence

“… As primary human microglia from living subjects are normally not accessible to researchers, there is a pressing need for an alternative source of authentic human microglia which allows modeling…”
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Germline genome-editing research and its socioethical implications Autor Ishii, Tetsuya

“…•In vitro research is not necessarily subject to moratorium.•Most importantly, the socioethical implications of the research need to be widely debated…”
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Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR Autor Tai, Derek J C, Ragavendran, Ashok, Manavalan, Poornima, Stortchevoi, Alexei, Seabra, Catarina M, Erdin, Serkan, Collins, Ryan L, Blumenthal, Ian, Chen, Xiaoli, Shen, Yiping, Sahin, Mustafa, Zhang, Chengsheng, Lee, Charles, Gusella, James F, Talkowski, Michael E

“…Recurrent, reciprocal genomic disorders due to non-allelic homologous recombination (NAHR) are a major cause of human disease. The authors developed a…”
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High-throughput assay and engineering of self-cleaving ribozymes by sequencing Autor Kobori, Shungo, Nomura, Yoko, Miu, Anh, Yokobayashi, Yohei

“… Additionally, self-cleaving ribozymes have been the subject of extensive engineering efforts for applications in synthetic biology…”
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Parameter estimation in biochemical pathways: a comparison of global optimization methods Autor Moles, Carmen G, Mendes, Pedro, Banga, Julio R

“… This problem is stated as a nonlinear programming (NLP) problem subject to nonlinear differential-algebraic constraints…”
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Carbon source regulation of antibiotic production Autor SANCHEZ Sergio, CHAVEZ Adan, FORERO Angela, GARCIA-HUANTE Yolanda, ROMERO Alba, SANCHEZ Mauricio, ROCHA Diana, SANCHEZ Brenda, AVALOS Mariana, GUZMAN-TRAMPE Silvia, RODRIGUEZ-SANOJA Romina, LANGLEY Elizabeth, RUIZ Beatriz

“… Among them, the effect of the carbon source has been the subject of continuous studies for both industry and research groups…”
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Genetic engineering of sex chromosomes for batch cultivation of non-transgenic, sex-sorted males Autor Das, Siba R., Maselko, Maciej, Upadhyay, Ambuj, Smanski, Michael J.

“…) control agents would be subject to additional governmental regulation. Here we describe and demonstrate a genetic method for the batch production of non-GE males…”
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Genome Editing with Engineered Nucleases in Economically Important Animals and Plants: State of the Art in the Research Pipeline Autor Sovová, Tereza, Kerins, Gerard, Demnerová, Kateřina, Ovesná, Jaroslava

“…After induced mutagenesis and transgenesis, genome editing is the next step in the development of breeding techniques. Genome editing using site-directed…”
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Genetic improvement of Saccharomyces cerevisiae for xylose fermentation Autor Chu, Byron C.H., Lee, Hung

“… years, this yeast has been the subject of various research efforts aimed at improving its ability to utilize xylose and ferment it to ethanol…”
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Cassava: constraints to production and the transfer of biotechnology to African laboratories Autor Bull, Simon E., Ndunguru, Joseph, Gruissem, Wilhelm, Beeching, John R., Vanderschuren, Hervé

“… Unfortunately, it is subject to numerous biotic and abiotic stresses that impact on production, consumption…”
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