Suchergebnisse - "Gandhi, Roopali"

The Host Shapes the Gut Microbiota via Fecal MicroRNA von Liu, Shirong, da Cunha, Andre Pires, Rezende, Rafael M, Cialic, Ron, Wei, Zhiyun, Bry, Lynn, Comstock, Laurie E, Gandhi, Roopali, Weiner, Howard L

“… The host gut microbiota varies across species and individuals but is relatively stable over time within an individual. How the host selectively shapes the …”
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A probiotic modulates the microbiome and immunity in multiple sclerosis von Tankou, Stephanie K., Regev, Keren, Healy, Brian C., Tjon, Emily, Laghi, Luca, Cox, Laura M., Kivisäkk, Pia, Pierre, Isabelle V., Hrishikesh, Lokhande, Gandhi, Roopali, Cook, Sandra, Glanz, Bonnie, Stankiewicz, James, Weiner, Howard L.

“… Objective Effect of a probiotic on the gut microbiome and peripheral immune function in healthy controls and relapsing‐remitting multiple sclerosis (MS) …”
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Alterations of the human gut microbiome in multiple sclerosis von Jangi, Sushrut, Gandhi, Roopali, Cox, Laura M., Li, Ning, von Glehn, Felipe, Yan, Raymond, Patel, Bonny, Mazzola, Maria Antonietta, Liu, Shirong, Glanz, Bonnie L., Cook, Sandra, Tankou, Stephanie, Stuart, Fiona, Melo, Kirsy, Nejad, Parham, Smith, Kathleen, Topçuolu, Begüm D., Holden, James, Kivisäkk, Pia, Chitnis, Tanuja, De Jager, Philip L., Quintana, Francisco J., Gerber, Georg K., Bry, Lynn, Weiner, Howard L.

“… The gut microbiome plays an important role in immune function and has been implicated in several autoimmune disorders. Here we use 16S rRNA sequencing to …”
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Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation von Srinivasan, Srimeenakshi, Yeri, Ashish, Cheah, Pike See, Chung, Allen, Danielson, Kirsty, De Hoff, Peter, Filant, Justyna, Laurent, Clara D, Laurent, Lucie D, Magee, Rogan, Moeller, Courtney, Murthy, Venkatesh L, Nejad, Parham, Paul, Anu, Rigoutsos, Isidore, Rodosthenous, Rodosthenis, Shah, Ravi V, Simonson, Bridget, To, Cuong, Wong, David, Yan, Irene K, Zhang, Xuan, Balaj, Leonora, Breakefield, Xandra O, Daaboul, George, Gandhi, Roopali, Lapidus, Jodi, Londin, Eric, Patel, Tushar, Raffai, Robert L, Sood, Anil K, Alexander, Roger P, Das, Saumya, Laurent, Louise C

“… Poor reproducibility within and across studies arising from lack of knowledge regarding the performance of extracellular RNA (exRNA) isolation methods has …”
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Role of the innate immune system in the pathogenesis of multiple sclerosis von Gandhi, Roopali, Laroni, Alice, Weiner, Howard L.

“… Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease with heterogeneous clinical presentations and course. MS is considered to be a T cell …”
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Circulating MicroRNAs as biomarkers for disease staging in multiple sclerosis von Gandhi, Roopali, Healy, Brian, Gholipour, Taha, Egorova, Svetlana, Musallam, Alexander, Hussain, Mohammad Shuja, Nejad, Parham, Patel, Bonny, Hei, Hillary, Khoury, Samia, Quintana, Francisco, Kivisakk, Pia, Chitnis, Tanuja, Weiner, Howard L.

“… Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate gene expression. Because they are stable in serum, they are being …”
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Investigation of probiotics in multiple sclerosis von Tankou, Stephanie K, Regev, Keren, Healy, Brian C, Cox, Laura M, Tjon, Emily, Kivisakk, Pia, Vanande, Isabelle P, Cook, Sandra, Gandhi, Roopali, Glanz, Bonnie, Stankiewicz, James, Weiner, Howard L

“… None of the disease-modifying therapies (DMTs) currently being used for the management of multiple sclerosis (MS) are 100% effective. In addition, side effects …”
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microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance von Fujiwara, Mai, Raheja, Radhika, Garo, Lucien P., Ajay, Amrendra K., Kadowaki-Saga, Ryoko, Karandikar, Sukrut H., Gabriely, Galina, Krishnan, Rajesh, Beynon, Vanessa, Paul, Anu, Patel, Amee, Saxena, Shrishti, Hu, Dan, Healy, Brian C., Chitnis, Tanuja, Gandhi, Roopali, Weiner, Howard L., Murugaiyan, Gopal

“… A disequilibrium between immunosuppressive Tregs and inflammatory IL-17-producing Th17 cells is a hallmark of autoimmune diseases, including multiple sclerosis …”
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AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice von Goettel, Jeremy A., Gandhi, Roopali, Kenison, Jessica E., Yeste, Ada, Murugaiyan, Gopal, Sambanthamoorthy, Sharmila, Griffith, Alexandra E., Patel, Bonny, Shouval, Dror S., Weiner, Howard L., Snapper, Scott B., Quintana, Francisco J.

“… Existing therapies for inflammatory bowel disease that are based on broad suppression of inflammation result in variable clinical benefit and unwanted side …”
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Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis von Raheja, Radhika, Regev, Keren, Healy, Brian C., Mazzola, Maria Antonietta, Beynon, Vanessa, Von Glehn, Felipe, Paul, Anu, Diaz‐Cruz, Camilo, Gholipour, Taha, Glanz, Bonnie I., Kivisakk, Pia, Chitnis, Tanuja, Weiner, Howard L., Berry, James D., Gandhi, Roopali

“… ABSTRACT Introduction: Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease …”
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Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE von Farez, Mauricio F, Quintana, Francisco J, Gandhi, Roopali, Izquierdo, Guillermo, Lucas, Miguel, Weiner, Howard L

“… The mediators that drive the progressive phase of multiple sclerosis remain undefined. Weiner and colleagues find that 15α-hydroxycholestene is expressed …”
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Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells von Mazzola, Maria Antonietta, Raheja, Radhika, Regev, Keren, Beynon, Vanessa, von Glehn, Felipe, Paul, Anu, Pierre, Isabelle, Kivisakk, Pia, Weiner, Howard L, Gandhi, Roopali

“… Dimethyl fumarate (DMF) and its active metabolite monomethyl fumarate (MMF) effectively lead to reduction in disease relapses and active magnetic resonance …”
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A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells von Lee, Sooncheol, Micalizzi, Douglas, Truesdell, Samuel S., Bukhari, Syed I. A., Boukhali, Myriam, Lombardi-Story, Jennifer, Kato, Yasutaka, Choo, Min-Kyung, Dey-Guha, Ipsita, Ji, Fei, Nicholson, Benjamin T., Myers, David T., Lee, Dongjun, Mazzola, Maria A., Raheja, Radhika, Langenbucher, Adam, Haradhvala, Nicholas J., Lawrence, Michael S., Gandhi, Roopali, Tiedje, Christopher, Diaz-Muñoz, Manuel D., Sweetser, David A., Sadreyev, Ruslan, Sykes, David, Haas, Wilhelm, Haber, Daniel A., Maheswaran, Shyamala, Vasudevan, Shobha

“… Background Quiescence (G0) is a transient, cell cycle-arrested state. By entering G0, cancer cells survive unfavorable conditions such as chemotherapy and …”
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IL-27 Imparts Immunoregulatory Function to Human NK Cell Subsets von Laroni, Alice, Gandhi, Roopali, Beynon, Vanessa, Weiner, Howard L.

“… Interleukin-27 (IL-27) is a cytokine with multiple roles in regulating the immune response, but its effect on human CD56(bright) and CD56(dim) NK cell subsets …”
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Hydralazine-Associated Antineutrophil Cytoplasmic Antibodies-Vasculitis Restricted to the Lungs von Chhabria, Mamta S, Mulkareddy, Vani, Pendela, Venkata S, Gandhi, Roopali G, Zafar, Aneeqa

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Satisfaction with alemtuzumab in relapsing multiple sclerosis patients: Results from the real-world PRO-ACT study von Wray, Sibyl, Jacques, Francois, Miller, Tamara A, Nicholas, Jacqueline A, Arroyo, Rafael, Travis, Lori, Khatri, Bhupendra, Chirieac, Magdalena, Gandhi, Roopali, Roesch, Nora, Rodrigues, Amelie, Melas-Melt, Lydie, Rawlings, Andreea M, Hunter, Samuel F

“… Background Patient-reported outcomes are increasingly used in the management of patients with multiple sclerosis to understand the patient's perspective of …”
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Effect of Natalizumab Treatment on Circulating Plasmacytoid Dendritic Cells: A Cross-Sectional Observational Study in Patients with Multiple Sclerosis von Kivisäkk, Pia, Francois, Katiana, Mbianda, Julvet, Gandhi, Roopali, Weiner, Howard L., Khoury, Samia J.

“… Dendritic cells (DCs) serve a critical role both in promoting and inhibiting adaptive immunity. The goal of this study was to investigate the effect of …”
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miRNA in multiple sclerosis: search for novel biomarkers von Gandhi, Roopali

“… A major challenge in multiple sclerosis (MS) is to develop biomarkers that could help in understanding individual MS patients, i.e. whether they are a …”
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Extracellular RNAs: development as biomarkers of human disease von Quinn, Joseph F., Patel, Tushar, Wong, David, Das, Saumya, Freedman, Jane E., Laurent, Louise C., Carter, Bob S., Hochberg, Fred, Keuren-Jensen, Kendall Van, Huentelman, Matt, Spetzler, Robert, S. Kalani, M. Yashar, Arango, Jorge, Adelson, P. David, Weiner, Howard L., Gandhi, Roopali, Goilav, Beatrice, Putterman, Chaim, Saugstad, Julie A.

“… Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by …”
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Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium von Laurent, Louise C., Abdel-Mageed, Asim B., Adelson, P. David, Arango, Jorge, Balaj, Leonora, Breakefield, Xandra, Carlson, Elizabeth, Carter, Bob S., Majem, Blanca, Chen, Clark C., Cocucci, Emanuele, Danielson, Kirsty, Courtright, Amanda, Das, Saumya, Elmageed, Zakaria Y. Abd, Enderle, Daniel, Ezrin, Alan, Ferrer, Marc, Freedman, Jane, Galas, David, Gandhi, Roopali, Huentelman, Matthew J., Van Keuren-Jensen, Kendall, Kalani, Yashar, Kim, Yong, Krichevsky, Anna M., Lai, Charles, Lal-Nag, Madhu, Laurent, Clara D., Leonardo, Trevor, Li, Feng, Malenica, Ivana, Mondal, Debasis, Nejad, Parham, Patel, Tushar, Raffai, Robert L., Rubio, Renee, Skog, Johan, Spetzler, Robert, Sun, Jie, Tanriverdi, Kahraman, Vickers, Kasey, Wang, Liang, Wang, Yaoyu, Wei, Zhiyun, Weiner, Howard L., Wong, David, Yan, Irene K., Yeri, Ashish, Gould, Stephen

“… Extracellular RNAs (exRNAs) have been identified in all tested biofluids and have been associated with a variety of extracellular vesicles, ribonucleoprotein …”
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