Suchergebnisse - "Gény, Bernard"

Mitochondrial Dysfunction and Oxidative Stress: Emerging Insights in Muscle and Cardiovascular Disease Mechanisms von Riou, Marianne, Geny, Bernard

“… Beyond their role as the “energy powerhouse” of the cell, mitochondria have emerged as essential actors in molecular signaling and determination of cellular …”
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The Effects of Glyphosate and Roundup® Herbicides on the Kidneys’ Cortex and the Medulla and on Renal Tubular Cells’ Mitochondrial Respiration and Oxidative Stress von Rihani, Rayhana, Charles, Anne-Laure, Oulehri, Walid, Geny, Bernard

“… Glyphosate (GP) and its derivatives are present in almost all environments and suspected to induce acute and chronic kidney injuries. This public health issue …”
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Similarities between COVID-19 and anti-MDA5 syndrome: what can we learn for better care? von Giannini, Margherita, Ohana, Mickael, Nespola, Benoit, Zanframundo, Giovanni, Geny, Bernard, Meyer, Alain

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Liability of Health Professionals Using Sensors, Telemedicine and Artificial Intelligence for Remote Healthcare von Geny, Marie, Andres, Emmanuel, Talha, Samy, Geny, Bernard

“… In the last few decades, there has been an ongoing transformation of our healthcare system with larger use of sensors for remote care and artificial …”
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Computer-assisted quantification and visualization of bowel perfusion using fluorescence-based enhanced reality in left-sided colonic resections von D’Urso, Antonio, Agnus, Vincent, Barberio, Manuel, Seeliger, Barbara, Marchegiani, Francesco, Charles, Anne-Laure, Geny, Bernard, Marescaux, Jacques, Mutter, Didier, Diana, Michele

“… Background Fluorescence-based enhanced reality (FLER) is a computer-based quantification method of fluorescence angiographies to evaluate bowel perfusion. The …”
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Mitochondria: An Organelle of Bacterial Origin Controlling Inflammation von Meyer, Alain, Laverny, Gilles, Bernardi, Livio, Charles, Anne Laure, Alsaleh, Ghada, Pottecher, Julien, Sibilia, Jean, Geny, Bernard

“… Inflammation is a cellular and molecular response to infection and/or tissues injury. While a suited inflammatory response in intensity and time allows for …”
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Autologous mitochondrial transplantation in male mice as a strategy to prevent deleterious effects of peripheral ischemia-reperfusion von Boutonnet, Lauréline, Mallard, Joris, Charles, Anne-Laure, Hucteau, Elyse, Geny, Bernard, Lejay, Anne, Grandperrin, Antoine

“… : Ischemia-reperfusion (IR) is known to induce severe tissue damage, notably through mitochondrial dysfunction. Mitochondrial transplantation has emerged as a …”
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Health benefits of aerobic training programs in adults aged 70 and over: a systematic review von Bouaziz, Walid, Vogel, Thomas, Schmitt, Elise, Kaltenbach, Georges, Geny, Bernard, Lang, Pierre Olivier

“… •This systematic review was conducted in 8 electronic databases.•53 articles meeting our inclusion criteria were considered in this review.•This review …”
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Sarcopenia and peripheral arterial disease: a systematic review von Pizzimenti, Mégane, Meyer, Alain, Charles, Anne‐Laure, Giannini, Margherita, Chakfé, Nabil, Lejay, Anne, Geny, Bernard

“… Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia are a population at risk requiring specific and targeted care. The …”
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IFNγ causes mitochondrial dysfunction and oxidative stress in myositis von Abad, Catalina, Pinal-Fernandez, Iago, Guillou, Clement, Bourdenet, Gwladys, Drouot, Laurent, Cosette, Pascal, Giannini, Margherita, Debrut, Lea, Jean, Laetitia, Bernard, Sophie, Genty, Damien, Zoubairi, Rachid, Remy-Jouet, Isabelle, Geny, Bernard, Boitard, Christian, Mammen, Andrew, Meyer, Alain, Boyer, Olivier

“… Idiopathic inflammatory myopathies (IIMs) are severe autoimmune diseases with poorly understood pathogenesis and unmet medical needs. Here, we examine the role …”
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Enhanced proteasome activity in perifascicular myofibres is a hallmark of dermatomyositis and its inhibition is efficient in preclinical models von Debrut, Léa, Giannini, Margherita, Quiring, Giulia, Perniola, Simone, Rovito, Daniela, Keime, Céline, Lannes, Béatrice, Nadaj-Pakleza, Aleksandra, Chanson, Jean-Baptiste, Charles, Anne-Laure, Geny, Bernard, Metzger, Daniel, Laverny, Gilles, Meyer, Alain

“… This study aims to characterise the molecular pathways underpinning perifascicular muscle fibre alterations to identify repositionable molecules for …”
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Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion von Paradis, Stéphanie, Charles, Anne-Laure, Meyer, Alain, Lejay, Anne, Scholey, James W, Chakfé, Nabil, Zoll, Joffrey, Geny, Bernard

“… Peripheral artery disease (PAD) is a common circulatory disorder of the lower limb arteries that reduces functional capacity and quality of life of patients …”
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Eccentric Exercise Training: Modalities, Applications and Perspectives von Isner-Horobeti, Marie-Eve, Dufour, Stéphane Pascal, Vautravers, Philippe, Geny, Bernard, Coudeyre, Emmanuel, Richard, Ruddy

“… Eccentric (ECC) exercise is classically used to improve muscle strength and power in healthy subjects and athletes. Due to its specific physiological and …”
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HYPerspectral Enhanced Reality (HYPER): a physiology-based surgical guidance tool von Barberio, Manuel, Longo, Fabio, Fiorillo, Claudio, Seeliger, Barbara, Mascagni, Pietro, Agnus, Vincent, Lindner, Veronique, Geny, Bernard, Charles, Anne-Laure, Gockel, Ines, Worreth, Marc, Saadi, Alend, Marescaux, Jacques, Diana, Michele

“… Background HSI is an optical technology allowing for a real-time, contrast-free snapshot of physiological tissue properties, including oxygenation …”
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Young Age and Concomitant Cannabis (THC) and Ethanol (EtOH) Exposure Enhances Rat Brain Damage Through Decreased Cerebral Mitochondrial Respiration von Quenardelle, Véronique, Charles, Anne-Laure, Charloux, Anne, Raul, Jean-Sébastien, Wolff, Valérie, Geny, Bernard

“… The reason why young people taking concomitantly cannabis (THC) and ethanol (EtOH) are more prone to stroke is underresearched. To investigate whether an …”
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Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1 von Bouitbir, Jamal, Charles, Anne-Laure, Echaniz-Laguna, Andoni, Kindo, Michel, Daussin, Frédéric, Auwerx, Johan, Piquard, François, Geny, Bernard, Zoll, Joffrey

“… Statins protect against cardiovascular-related mortality but induce skeletal muscle toxicity. To investigate mechanisms of statins, we tested the hypothesis …”
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The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure von Lugnier, Claire, Meyer, Alain, Charloux, Anne, Andrès, Emmanuel, Gény, Bernard, Talha, Samy

“… Besides pumping, the heart participates in hydro-sodium homeostasis and systemic blood pressure regulation through its endocrine function mainly represented by …”
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A Systematic Review of the Complex Effects of Cannabinoids on Cerebral and Peripheral Circulation in Animal Models von Richter, J. Sebastian, Quenardelle, Véronique, Rouyer, Olivier, Raul, Jean Sébastien, Beaujeux, Rémy, Gény, Bernard, Wolff, Valérie

“… While cannabis is perceived as a relatively safe drug by the public, accumulating clinical data suggest detrimental cardiovascular effects of cannabinoids …”
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Accuracy of Rhythm Diagnostic Systems’ MultiSense® in Detection of Arterial Oxygen Saturation and Respiratory Rate During Hypoxia in Humans: Effects of Skin Color and Device Localization von Evrard, Charles, El Attaoui, Amina, Pistea, Cristina, Enache, Irina, Marriott, Mark, Mayaud, Louis, Charloux, Anne, Geny, Bernard

“… The continuous monitoring of oxygen saturation (SpO2) and respiratory rates (RRs) are major clinical issues in many cardio-respiratory diseases and have been …”
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Scleromyositis: A distinct novel entity within the systemic sclerosis and autoimmune myositis spectrum. Implications for care and pathogenesis von Giannini, Margherita, Ellezam, Benjamin, Leclair, Valérie, Lefebvre, Frédéric, Troyanov, Yves, Hudson, Marie, Senécal, Jean-Luc, Geny, Bernard, Landon-Cardinal, Océane, Meyer, Alain

“… Systemic sclerosis and autoimmune myositis are both associated with decreased quality of life and increased mortality. Their prognosis and management largely …”
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