Výsledky vyhľadávania - "Frey, Melissa K."

Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening Autor Offit, Kenneth, Tkachuk, Kaitlyn A, Stadler, Zsofia K, Walsh, Michael F, Diaz-Zabala, Hector, Levin, Jeffrey D, Steinsnyder, Zoe, Ravichandran, Vignesh, Sharaf, Ravi N, Frey, Melissa K, Lipkin, Steven M, Robson, Mark E, Hamilton, Jada G, Vijai, Joseph, Mukherjee, Semanti

“…Despite advances in DNA sequencing technology and expanded medical guidelines, the vast majority of individuals carrying pathogenic variants of common cancer…”
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Universal endometrial cancer tumor typing: How much has immunohistochemistry, microsatellite instability, and MLH1 methylation improved the diagnosis of Lynch syndrome across the population? Autor Kahn, Ryan M., Gordhandas, Sushmita, Maddy, Brandon Paul, Baltich Nelson, Becky, Askin, Gulce, Christos, Paul J., Caputo, Thomas A., Chapman‐Davis, Eloise, Holcomb, Kevin, Frey, Melissa K.

“…Background Universal tumor testing for defective DNA mismatch repair (MMR) is recommended for all women diagnosed with endometrial cancer to identify those…”
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Financial toxicity, mental health, and gynecologic cancer treatment: The effect of the COVID‐19 pandemic among low‐income women in New York City Autor Chen, Yiting Stefanie, Zhou, Zhen Ni, Glynn, Shannon M., Frey, Melissa K., Balogun, Onyinye D., Kanis, Margaux, Holcomb, Kevin, Gorelick, Constantine, Thomas, Charlene, Christos, Paul J., Chapman‐Davis, Eloise

“…BACKGROUND New York City (NYC) emerged as an epicenter of the COVID‐19 pandemic, and marginalized populations were affected at disproportionate rates. The…”
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Digital tool for genetic cancer risk assessment in a historically underserved population: a randomized controlled trial Autor Webster, Emily M., Ahsan, Muhammad Danyal, Chandler, Isabelle R., Primiano, Michelle, Mcdougale, Auja, Howard, Denise, Fishman, David, Rosenberg, Shoshana M., Chapman-Davis, Eloise, Levi, Sarah, Grant, Benjamin, Bull, Leslie E., Christos, Paul, Sharaf, Ravi N., Frey, Melissa K.

“…Up to 95% of individuals with cancer-predisposing germline pathogenic variants in the U.S. remain unidentified, particularly among historically underserved…”
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Navigating dual risks: Ovarian cancer prevention and cardiovascular health in patients with hereditary cancer syndromes Autor Keenahan, Laura, Ahsan, Muhammad Danyal, Mecklai, Alicia, Frey, Melissa K.

“…•Surgical removal of ovaries and fallopian tubes is recommended for many hereditary cancer syndrome carriers before menopause.•Premature surgical menopause is…”
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Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes Autor Liu, Ying L, Breen, Kelsey, Catchings, Amanda, Ranganathan, Megha, Latham, Alicia, Goldfrank, Deborah J, Grisham, Rachel N, Long Roche, Kara, Frey, Melissa K, Chi, Dennis S, Abu-Rustum, Nadeem, Aghajanian, Carol, Offit, Kenneth, Stadler, Zsofia K

“…Pathogenic germline variants underlie up to 20% of ovarian cancer (OC) and are associated with varying degrees of risk for OC. For mutations in high-penetrance…”
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Prevalence of nonfounder BRCA1/2 mutations in Ashkenazi Jewish patients presenting for genetic testing at a hereditary breast and ovarian cancer center Autor Frey, Melissa K., Kopparam, Rohini V., Ni Zhou, Zhen, Fields, Jessica C., Buskwofie, Ama, Carlson, Ann D., Caputo, Thomas, Holcomb, Kevin, Chapman‐Davis, Eloise

“…Background Genetic assessment in Ashkenazi Jewish (AJ) patients often is limited to BRCA1/2 founder mutation testing. With access to time‐efficient and…”
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Protocol for Health Risk Information Technology-Assisted Genetic Evaluation (HeRITAGE): a randomised controlled trial of digital genetic cancer risk assessment in a diverse underserved gynaecology clinic Autor Bull, Leslie E, Webster, Emily M, McDougale, Auja, Howard, Denise, Ahsan, Muhammad Danyal, Levi, Sarah, Grant, Benjamin, Chandler, Isabelle, Christos, Paul, Sharaf, Ravi N, Frey, Melissa K

“…IntroductionIn the USA, up to 95% of individuals harbouring cancer-predisposing germline pathogenic variants have not been identified despite recommendations…”
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Do people with hereditary cancer syndromes inform their at-risk relatives? A systematic review and meta-analysis Autor Ahsan, Muhammad Danyal, Levi, Sarah R., Webster, Emily M., Bergeron, Hannah, Lin, Jenny, Narayan, Priyanka, Nelson, Becky Baltich, Li, Xuan, Fowlkes, Rana K., Brewer, Jesse T., Thomas, Charlene, Christos, Paul J., Chapman-Davis, Eloise, Cantillo, Evelyn, Holcomb, Kevin, Sharaf, Ravi N., Frey, Melissa K.

“…To evaluate rates of familial disclosure of hereditary cancer syndrome information. A systematic review and meta-analysis was conducted in accordance with…”
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Reply to Dr. Witjes regarding universal tumor genomic sequencing as a prescreen for germline genetic testing in patients diagnosed with ovarian cancer Autor Lin, Jenny, Frey, Melissa K.

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Evaluation of lysophosphatidic acid in vaginal fluid as a biomarker for ovarian cancer: A pilot study Autor Minis, Evelyn, Holcomb, Kevin, Sisti, Giovanni, Nasioudis, Dimitrios, Kanninen, Tomi T., Athanasiou, Aikaterini, Frey, Melissa K., Chapman-Davis, Eloise, Caputo, Thomas A., Witkin, Steven S.

“…There remains a need to differentiate between women with a benign or a malignant adnexal mass prior to surgery. As part of an ongoing evaluation of vaginal…”
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Ovarian cancer survivors' acceptance of treatment side effects evolves as goals of care change over the cancer continuum Autor Frey, Melissa K., Ellis, Annie E., Koontz, Laura M., Shyne, Savannah, Klingenberg, Bernhard, Fields, Jessica C., Chern, Jing-Yi, Blank, Stephanie V.

“…Women with ovarian cancer can have long overall survival and goals of treatment change over time from cure to remission to stable disease. We sought to…”
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Impact of postoperative intensity-modulated radiation therapy (IMRT) on the rate of bowel obstruction in gynecologic malignancy Autor Shih, Karin K., Hajj, Carla, Kollmeier, Marisa, Frey, Melissa K., Sonoda, Yukio, Abu-Rustum, Nadeem R., Alektiar, Kaled M.

“…The purpose was to determine the potential impact of IMRT on the rate of bowel obstruction (BO), in patients with gynecologic malignancies undergoing…”
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The influence of BRCA variants of unknown significance on cancer risk management decision-making Autor Chern, Jing-Yi, Lee, Sarah S., Frey, Melissa K., Lee, Jessica, Blank, Stephanie V.

“…To compare gynecological cancer risk management between women with BRCA variants of unknown significance (VUS) to women with negative genetic testing…”
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Ovarian cancer arising from the proximal fallopian tube in a patient with a BRCA2 mutation Autor Badiner, Nora, Nchako, Corbyn M., Ma, Lucy, Frey, Melissa K.

“…•BRCA1/2 carriers are at high risk for fallopian tube carcinoma, which can arise in the proximal fallopian tube.•Pathologic analysis of RRBSO specimens should…”
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Could Fertility-Sparing Surgery be Considered for Women With Early Stage Ovarian Clear Cell Carcinoma Autor Nasioudis, Dimitrios, Chapman-Davis, Eloise, Frey, Melissa K., Witkin, Steven S., Holcomb, Kevin

“…The aim of the present retrospective population-based study was to investigate the oncologic impact of uterine and ovarian preservation (OP) in premenopausal…”
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Attitudes and beliefs regarding complementary and alternative medicine in a diverse gynecologic oncology patient population Autor Miller, Emily A., Beaumont, Shanice, Zhou, Zhen Ni, Brewer, Jesse T., Thomas, Charlene, Chapman-Davis, Eloise, Cantillo, Evelyn, Holcomb, Kevin, Pua, Tara, Frey, Melissa K.

“…•Complementary and alternative medicine use among diverse gynecologic oncology patients is less common than expected.•Race and ethnicity influence perceived…”
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Enhanced recovery Pathways in gynecologic surgery: Are they safe and effective in the elderly? Autor Lee, Sarah S., Chern, Jing-Yi, Frey, Melissa K., Comfort, Ashley, Lee, Jessica, Roselli, Nicole, Boyd, Leslie R.

“…•Data on the safety of ERP in elderly patients undergoing complex gynecologic surgery is sparse.•Elderly patients undergoing gynecologic laparotomy achieved…”
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Metastatic epithelial ovarian cancer to Meckel’s cave with leptomeningeal spread at time of diagnosis Autor Kahn, Ryan Matthew, Gandhi, Shreena Kamlesh, Mvula, Mwamba Rebecca, Li, Xuan, Frey, Melissa K.

“…•Rare case of aggressive epithelial ovarian cancer with brain metastasis at time of initial diagnosis.•First reported case of epithelial ovarian cancer with…”
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Room for improvement in capturing cancer family history in a gynecologic oncology outpatient setting Autor Lin, Jenny, Wolfe, Isabel, Ahsan, Muhammad Danyal, Krinsky, Hannah, Lackner, Andreas I., Pelt, Joe, Bolouvi, Karen, Gamble, Charlotte, Thomas, Charlene, Christos, Paul J., Cantillo, Evelyn, Holcomb, Kevin, Chapman-Davis, Eloise, Sharaf, Ravi, Lipkin, Steven M., Blank, Stephanie V., Frey, Melissa K.

“…•Collection of family health history is necessary for identifying patients at risk for hereditary cancer.•Patients with either a relative with cancer or prior…”
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