Výsledky vyhľadávania - "Frasch, F."

Reflections on the OECD guidelines for in vitro skin absorption studies Autor Hopf, N.B., Champmartin, C., Schenk, L., Berthet, A., Chedik, L., Du Plessis, J.L., Franken, A., Frasch, F., Gaskin, S., Johanson, G., Julander, A., Kasting, G., Kilo, S., Larese Filon, F., Marquet, F., Midander, K., Reale, E., Bunge, A.L.

“…At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals (OEESC) (16–18 September 2019) in Dublin, Ireland, several…”
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A Random Walk Model of Skin Permeation Autor Frederick Frasch, H.

“…A new mathematical model for permeability of chemicals in aqueous vehicle through skin is presented. The rationale for this model is to represent diffusion by…”
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Modeling of Diffusion with Partitioning in Stratum Corneum Using a Finite Element Model Autor Barbero, Ana M., Frasch, H. F.

“…Partitioning and diffusion of chemicals in skin is of interest to researchers in areas such as transdermal penetration and drug disposition, either for risk…”
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Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. 2. Pathophysiology Autor Marshall, B E, Hanson, C W, Frasch, F, Marshall, C

“…In this review, the second of a two part series, the analytic techniques introduced in the first part are applied to a broad range of pulmonary…”
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Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. 1. Physiologic concepts Autor Marshall, B E, Marshall, C, Frasch, F, Hanson, C W

“…The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and…”
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Causes of hypercarbia with oxygen therapy in patients with chronic obstructive pulmonary disease Autor Hanson, 3rd, C W, Marshall, B E, Frasch, H F, Marshall, C

“…To compare data derived from a computer model of the pulmonary circulation with data from a case series of patients with chronic obstructive pulmonary disease…”
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Effects of venous pressure on coronary circulation and intramyocardial fluid mechanics Autor Izrailtyan, I, Frasch, H F, Kresh, J Y

“…This investigation examined the interaction between right heart pressure (RHP), coronary perfusion pressure (CPP), intramyocardial tissue pressure (IMP), and…”
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Two-port analysis of microcirculation: an extension of windkessel Autor Frasch, H F, Kresh, J Y, Noordergraaf, A

“…We examined the suitability of the three-element windkessel as a reduced model of pulsatile pressure-flow relations at arteriolar and venular ends of a…”
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Endothelin-1 is elevated in monocrotaline pulmonary hypertension Autor Frasch, H Frederick, Marshall, Carol, Marshall, Bryan E

“…These studies document striking pulmonary vasoconstrictor response to nitric oxide synthase (NOS) inhibition in monocrotaline (MCT) pulmonary hypertension in…”
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Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review Autor Barbero, Ana M., Frasch, H. Frederick

“…Both human and animal skin in vitro models are used to predict percutaneous penetration in humans. The objective of this review is a quantitative comparison of…”
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Pulse reflection sites and effective length of the arterial system Autor Campbell, K B, Lee, L C, Frasch, H F, Noordergraaf, A

“…The concept of effective length (L) of the arterial system implies that it may be represented by a single viscoelastic tube terminated by an impedance,…”
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Application of solid-phase microextraction to in vitro skin permeation experiments: example using diethyl phthalate Autor Frasch, H. Fred, Barbero, Ana M.

“…The application of automated solid-phase microextraction (SPME) as a sample preparation technique for in vitro studies of skin permeation is described, using…”
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Sequential V(A)/Q distributions in the normal rabbit by micropore membrane inlet mass spectrometry Autor Baumgardner, J E, Choi, I C, Vonk-Noordegraaf, A, Frasch, H F, Neufeld, G R, Marshall, B E

“…We developed micropore membrane inlet mass spectrometer (MMIMS) probes to rapidly measure inert-gas partial pressures in small blood samples. The mass…”
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Wave transmission and input impedance of a model of skeletal muscle microvasculature Autor Frasch, H F, Kresh, J Y, Noordergraaf, A

“…We analyzed wave transmission properties and input impedance of a microvascular network model. The model, derived from rat spinotrapezius muscle and previously…”
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Random sampling or ‘random’ model in skin flux measurements? [Commentary on “Investigation of the mechanism of flux across human skin in vitro by quantitative structure–permeability relationships”] Autor Poda, Gennadiy I, Landsittel, Douglas P, Brumbaugh, Kurt, Sharp, Dan S, Frasch, H.Frederick, Demchuk, Eugene

“…Transdermal therapy receives increasing attention as an attractive alternative to traditional drug delivery. Unfortunately the exact algorithm of transdermal…”
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Third Culture Kids, their diversity beliefs and their intercultural competences Autor de Waal, Monika F., Born, Marise Ph, Brinkmann, Ursula, Frasch, Jona J.F.

“…Positive diversity beliefs are known to increase the effectiveness of diverse groups in organizations and society. Early cross-cultural experiences might…”
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Steady-state flux and lag time in the stratum corneum lipid pathway: results from finite element models Autor Frasch, H Frederick, Barbero, Ana M

“…Finite element model (FEM) solutions of the diffusion through two-dimensional representations of the stratum corneum (SC) lipid pathway are presented. Both…”
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Skin Penetration And Lag Times Of Neat And Aqueous Diethyl Phthalate, 1,2-Dichloroethane And Naphthalene Autor Frederick Frasch, H., Barbero, Ana M., Alachkar, Houda, McDougal, James N.

“…Cutaneous exposures to occupational chemicals may cause toxic effects. For any chemical, the potential for systemic toxicity from dermal exposure depends on…”
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Chronic Stability of Bipolar Epicardial Plunge Electrodes in Dogs Autor Brautigam, Robert T., Porter, R. Stephen, Frasch, Fred, Kutalek, Steven P.

“…We constructed and surgically implanted 114 chronic bipolar epicardial plunge electrodes for programmed left ventricular stimulation in closed chest dogs; 88…”
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Improved oxygenation with prostaglandin F2alpha with and without inhaled nitric oxide in dogs Autor Marshall, B E, Chen, L, Frasch, H F, Hanson, C W, Marshall, C

“…Dogs of mixed breed (n = 7) were anesthetized, right lung atelectasis was established, and the cyclooxygenase pathway was blocked with ibuprofen. Measurements…”
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