Výsledky vyhľadávania - "Francesco Grussu"

Uncertainty modelling in deep learning for safer neuroimage enhancement: Demonstration in diffusion MRI Autor Tanno, Ryutaro, Worrall, Daniel E., Kaden, Enrico, Ghosh, Aurobrata, Grussu, Francesco, Bizzi, Alberto, Sotiropoulos, Stamatios N., Criminisi, Antonio, Alexander, Daniel C.

“…•Proposes methods for modelling different types of uncertainty that arise in deep learning (DL) applications for image enhancement problems.•Demonstrates in…”
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Robust imaging habitat computation using voxel-wise radiomics features Autor Bernatowicz, Kinga, Grussu, Francesco, Ligero, Marta, Garcia, Alonso, Delgado, Eric, Perez-Lopez, Raquel

“…Tumor heterogeneity has been postulated as a hallmark of treatment resistance and a cure constraint in cancer patients. Conventional quantitative medical…”
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Reduced neurite density in the brain and cervical spinal cord in relapsing-remitting multiple sclerosis: A NODDI study Autor Collorone, Sara, Cawley, Niamh, Grussu, Francesco, Prados, Ferran, Tona, Francesca, Calvi, Alberto, Kanber, Baris, Schneider, Torben, Kipp, Lucas, Zhang, Hui, Alexander, Daniel C, Thompson, Alan J, Toosy, Ahmed, Wheeler-Kingshott, Claudia Am Gandini, Ciccarelli, Olga

“…Multiple sclerosis (MS) affects both brain and spinal cord. However, studies of the neuraxis with advanced magnetic resonance imaging (MRI) are rare because of…”
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Multi-parametric quantitative in vivo spinal cord MRI with unified signal readout and image denoising Autor Grussu, Francesco, Battiston, Marco, Veraart, Jelle, Schneider, Torben, Cohen-Adad, Julien, Shepherd, Timothy M., Alexander, Daniel C., Fieremans, Els, Novikov, Dmitry S., Gandini Wheeler-Kingshott, Claudia A.M.

“…Multi-parametric quantitative MRI (qMRI) of the spinal cord is a promising non-invasive tool to probe early microstructural damage in neurological disorders…”
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Voxel-level analysis of normalized DSC-PWI time-intensity curves: a potential generalizable approach and its proof of concept in discriminating glioblastoma and metastasis Autor Pons-Escoda, Albert, Garcia-Ruiz, Alonso, Naval-Baudin, Pablo, Grussu, Francesco, Fernandez, Juan Jose Sanchez, Simo, Angels Camins, Sarro, Noemi Vidal, Fernandez-Coello, Alejandro, Bruna, Jordi, Cos, Monica, Perez-Lopez, Raquel, Majos, Carles

“…Objective Standard DSC-PWI analyses are based on concrete parameters and values, but an approach that contemplates all points in the time-intensity curves and…”
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Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology? Autor Grussu, Francesco, Schneider, Torben, Tur, Carmen, Yates, Richard L., Tachrount, Mohamed, Ianuş, Andrada, Yiannakas, Marios C., Newcombe, Jia, Zhang, Hui, Alexander, Daniel C., DeLuca, Gabriele C., Gandini Wheeler‐Kingshott, Claudia A. M.

“…Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal cord is limited by low specificity regarding the underlying…”
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Brain microstructural and metabolic alterations detected in vivo at onset of the first demyelinating event Autor Collorone, Sara, Prados, Ferran, Kanber, Baris, Cawley, Niamh M, Tur, Carmen, Grussu, Francesco, Solanky, Bhavana S, Yiannakas, Marios, Davagnanam, Indran, Wheeler-Kingshott, Claudia A M Gandini, Barkhof, Frederik, Ciccarelli, Olga, Toosy, Ahmed T

“…In early multiple sclerosis, a clearer understanding of normal-brain tissue microstructural and metabolic abnormalities will provide valuable insights into its…”
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Diffusion MRI signal cumulants and hepatocyte microstructure at fixed diffusion time: Insights from simulations, 9.4T imaging, and histology Autor Grussu, Francesco, Bernatowicz, Kinga, Casanova‐Salas, Irene, Castro, Natalia, Nuciforo, Paolo, Mateo, Joaquin, Barba, Ignasi, Perez‐Lopez, Raquel

“…Purpose Relationships between diffusion‐weighted MRI signals and hepatocyte microstructure were investigated to inform liver diffusion MRI modeling, focusing…”
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Evaluation of magnetic resonance spectroscopy total sodium concentration measures, and associations with microstructure and physical impairment in cervical myelopathy Autor Solanky, Bhavana S., Prados, Ferran, Tur, Carmen, Grussu, Francesco, Al-Ahmad, Selma, Yang, Xixi, Bianchi, Alessia, Kanber, Baris, Russo, Antonino, Russo, Vittorio, Choi, David, Panicker, Jalesh N., Wheeler-Kingshott, Claudia A. M. Gandini

“…Spinal cord injury causes a cascade of physiological responses, which may trigger a subsequent neurotoxic increase in intracellular sodium. This can lead to…”
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Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy Autor Prados, Ferran, Moccia, Marcello, Johnson, Aubrey, Yiannakas, Marios, Grussu, Francesco, Cardoso, Manuel Jorge, Ciccarelli, Olga, Ourselin, Sebastien, Barkhof, Frederik, Wheeler-Kingshott, Claudia

“…Spinal cord atrophy measurements obtained from structural magnetic resonance imaging (MRI) are associated with disability in many neurological diseases and…”
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What contributes to disability in progressive MS? A brain and cervical cord-matched quantitative MRI study Autor Tur, Carmen, Battiston, Marco, Yiannakas, Marios C, Collorone, Sara, Calvi, Alberto, Prados, Ferran, Kanber, Baris, Grussu, Francesco, Ricciardi, Antonio, Pajak, Patrizia, Martinelli, Daniele, Schneider, Torben, Ciccarelli, Olga, Samson, Rebecca S, Wheeler-Kingshott, Claudia Am Gandini

“…We assessed the ability of a brain-and-cord-matched quantitative magnetic resonance imaging (qMRI) protocol to differentiate patients with progressive multiple…”
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Relevance of time‐dependence for clinically viable diffusion imaging of the spinal cord Autor Grussu, Francesco, Ianuş, Andrada, Tur, Carmen, Prados, Ferran, Schneider, Torben, Kaden, Enrico, Ourselin, Sébastien, Drobnjak, Ivana, Zhang, Hui, Alexander, Daniel C., Gandini Wheeler‐Kingshott, Claudia A. M.

“…Purpose Time‐dependence is a key feature of the diffusion‐weighted (DW) signal, knowledge of which informs biophysical modelling. Here, we study…”
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Feasibility of in vivo multi-parametric quantitative magnetic resonance imaging of the healthy sciatic nerve with a unified signal readout protocol Autor Boonsuth, Ratthaporn, Battiston, Marco, Grussu, Francesco, Samlidou, Christina Maria, Calvi, Alberto, Samson, Rebecca S., Gandini Wheeler-Kingshott, Claudia A. M., Yiannakas, Marios C.

“…Magnetic resonance neurography (MRN) has been used successfully over the years to investigate the peripheral nervous system (PNS) because it allows early…”
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A multi-shell multi-tissue diffusion study of brain connectivity in early multiple sclerosis Autor Tur, Carmen, Grussu, Francesco, Prados, Ferran, Charalambous, Thalis, Collorone, Sara, Kanber, Baris, Cawley, Niamh, Altmann, Daniel R, Ourselin, Sébastien, Barkhof, Frederik, Clayden, Jonathan D, Toosy, Ahmed T, Wheeler-Kingshott, Claudia Am Gandini, Ciccarelli, Olga

“…The potential of multi-shell diffusion imaging to produce accurate brain connectivity metrics able to unravel key pathophysiological processes in multiple…”
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Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction Autor Bernatowicz, Kinga, Amat, Ramon, Prior, Olivia, Frigola, Joan, Ligero, Marta, Grussu, Francesco, Zatse, Christina, Serna, Garazi, Nuciforo, Paolo, Toledo, Rodrigo, Escobar, Manel, Garralda, Elena, Felip, Enriqueta, Perez-Lopez, Raquel

“…BackgroundThe efficacy of immune checkpoint inhibitors (ICIs) depends on the tumor immune microenvironment (TIME), with a preference for a T cell-inflamed…”
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Comparison of Neurite Orientation Dispersion and Density Imaging and Two-Compartment Spherical Mean Technique Parameter Maps in Multiple Sclerosis Autor Johnson, Daniel, Ricciardi, Antonio, Brownlee, Wallace, Kanber, Baris, Prados, Ferran, Collorone, Sara, Kaden, Enrico, Toosy, Ahmed, Alexander, Daniel C., Gandini Wheeler-Kingshott, Claudia A. M., Ciccarelli, Olga, Grussu, Francesco

“…Background: Neurite orientation dispersion and density imaging (NODDI) and the spherical mean technique (SMT) are diffusion MRI methods providing metrics with…”
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Histology-informed microstructural diffusion simulations for MRI cancer characterisation—the Histo-μSim framework Autor Grigoriou, Athanasios, Macarro, Carlos, Palombo, Marco, Navarro-Garcia, Daniel, Voronova, Anna Kira, Bernatowicz, Kinga, Barba, Ignasi, Escriche, Alba, Greco, Emanuela, Abad, María, Simonetti, Sara, Serna, Garazi, Mast, Richard, Merino, Xavier, Roson, Núria, Escobar, Manuel, Vieito, Maria, Nuciforo, Paolo, Toledo, Rodrigo, Garralda, Elena, Sala-Llonch, Roser, Fieremans, Els, Novikov, Dmitry S., Perez-Lopez, Raquel, Grussu, Francesco

“…Diffusion Magnetic Resonance Imaging (dMRI) simulations in geometries mimicking the microscopic complexity of human tissues enable the development of…”
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Assessing Lumbar Plexus and Sciatic Nerve Damage in Relapsing-Remitting Multiple Sclerosis Using Magnetisation Transfer Ratio Autor Boonsuth, Ratthaporn, Samson, Rebecca S., Tur, Carmen, Battiston, Marco, Grussu, Francesco, Schneider, Torben, Yoneyama, Masami, Prados, Ferran, Ttofalla, Antrea, Collorone, Sara, Cortese, Rosa, Ciccarelli, Olga, Gandini Wheeler-Kingshott, Claudia A. M., Yiannakas, Marios C.

“…Background: Multiple sclerosis (MS) has traditionally been regarded as a disease confined to the central nervous system (CNS). However, neuropathological,…”
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Patterns of inflammation, microstructural alterations, and sodium accumulation define multiple sclerosis subtypes after 15 years from onset Autor Ricciardi, Antonio, Grussu, Francesco, Kanber, Baris, Prados, Ferran, Yiannakas, Marios C., Solanky, Bhavana S., Riemer, Frank, Golay, Xavier, Brownlee, Wallace, Ciccarelli, Olga, Alexander, Daniel C., Gandini Wheeler-Kingshott, Claudia A. M.

“…Conventional MRI is routinely used for the characterization of pathological changes in multiple sclerosis (MS), but due to its lack of specificity is unable to…”
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Spatial patterns of brain lesions assessed through covariance estimations of lesional voxels in multiple Sclerosis: The SPACE-MS technique Autor Tur, Carmen, Grussu, Francesco, De Angelis, Floriana, Prados, Ferran, Kanber, Baris, Calvi, Alberto, Eshaghi, Arman, Charalambous, Thalis, Cortese, Rosa, Chard, Declan T., Chataway, Jeremy, Thompson, Alan J., Ciccarelli, Olga, Gandini Wheeler-Kingshott, Claudia A.M.

“…[Display omitted] •We present SPACE-MS, a tool to assess the spatial distribution of brain lesions.•SPACE-MS metrics mainly reflect caudality and spatial…”
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