Výsledky vyhledávání - "Forced Expiratory Volume"

Directional dominance on stature and cognition in diverse human populations Autor Esko, Tonu, Nutile, Teresa, Jackson, Anne U., Schurmann, Claudia, Stančáková, Alena, Zhao, Wei, Enroth, Stefan, Guo, Xiuqing, Chasman, Daniel I., Rietveld, Cornelius A., Pattaro, Cristian, Vuckovic, Dragana, Bouchard, Claude, Benton, Miles C., Drong, Alexander, Yengo, Loic, Bielak, Lawrence F., Zhi, Degui, Mägi, Reedik, Karaderi, Tugce, Liu, Tian, van der Laan, Sander W., Asselbergs, Folkert W., Barr, R. Graham, Baumeister, Sebastian E., Benjamin, Daniel J., Boerwinkle, Eric, Chanock, Stephen J., Gillham-Nasenya, Irina, Gottesman, Omri, Grodstein, Francine, Gu, Charles, Huang, Jinyan, Ingelsson, Erik, Johansson, Åsa, Jukema, J. Wouter, Kähönen, Mika, Koellinger, Philipp, Kooner, Manraj K., Lahti, Jari, Lu, Yingchang, Lundqvist, Annamari, Männistö, Satu, Matchan, Angela, Mathias, Rasika A., Meitinger, Thomas, Morrison, Alanna, Nadukuru, Rajiv, Nelis, Mari, Nieminen, Markku S., Patarcic, Inga, Peyser, Patricia A., Prokopenko, Inga, Rose, Lynda M., Sala, Cinzia, Sarin, Antti-Pekka, Schmidt, Helena, Sennblad, Bengt, Seshadri, Sudha, Smith, Blair H., Smith, Jennifer A., Southam, Lorraine, Stathopoulou, Maria G., Strawbridge, Rona J., Taylor, Kent D., Tuomilehto, Jaakko, Vaidya, Dhananjay, Vasankari, Tuula, Vedantam, Sailaja, Vuoksimaa, Eero, Whitfield, John B., Willemsen, Gonneke, Zaza, Gianluigi, Melbye, Mads, Bisgaard, Hans, Cooper, Richard S., Froguel, Philippe, Pasterkamp, Gerard, Ferrucci, Luigi, Scott, Robert A., Morris, Andrew D., Deloukas, Panos, Lindgren, Cecilia M., Timpson, Nicholas J., Munroe, Patricia B., Gambaro, Giovanni, Morris, Andrew P., Eriksson, Johan G., Martin, Nicholas G., Hunt, Steven C., Kaprio, Jaakko, Becker, Diane M., Bharadwaj, Dwaipayan, Boehnke, Michael, Metspalu, Andres, Dupuis, Josée, Vollenweider, Peter, Rotter, Jerome I., Weir, David R., Chambers, John C.

“…An analysis of 16 health-related quantitative traits in approximately 350,000 individuals reveals statistically significant associations between genome-wide…”
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Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma Autor Castro, Mario, Corren, Jonathan, Pavord, Ian D, Maspero, Jorge, Wenzel, Sally, Rabe, Klaus F, Busse, William W, Ford, Linda, Sher, Lawrence, FitzGerald, J. Mark, Katelaris, Constance, Tohda, Yuji, Zhang, Bingzhi, Staudinger, Heribert, Pirozzi, Gianluca, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Khan, Asif, Chao, Jingdong, Martincova, Renata, Graham, Neil M.H, Hamilton, Jennifer D, Swanson, Brian N, Stahl, Neil, Yancopoulos, George D, Teper, Ariel

“…Treatment of uncontrolled asthma with dupilumab, an anti–interleukin-4 and anti–interleukin-13 receptor monoclonal antibody, in addition to usual therapy, led…”
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The Abbreviated Methacholine Challenge Test is Safe for Children Autor Hevroni, Avigdor, Nemet, Shay, Ringel, Amit, Boursheh, Laurice, Handler, Nitay Alter, Bar-Yishay, Ephraim

“…To evaluate the safety of an abbreviated methacholine challenge test (MCT) protocol in children. This prospective, observational study enrolled children aged 6…”
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Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial Autor Chapman, Kenneth R, Burdon, Jonathan G W, Piitulainen, Eeva, Sandhaus, Robert A, Seersholm, Niels, Stocks, James M, Stoel, Berend C, Huang, Liping, Yao, Zhenling, Edelman, Jonathan M, McElvaney, Noel G

“…The efficacy of α1 proteinase inhibitor (A1PI) augmentation treatment for α1 antitrypsin deficiency has not been substantiated by a randomised,…”
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Pharmacotherapy and Lung Function Decline in Patients with Chronic Obstructive Pulmonary Disease. A Systematic Review Autor Celli, Bartolome R, Anderson, Julie A, Cowans, Nicholas J, Crim, Courtney, Hartley, Benjamin F, Martinez, Fernando J, Morris, Andrea N, Quasny, Holly, Yates, Julie, Vestbo, Jørgen, Calverley, Peter M A

“…Whether pharmacological therapy alters decline in FEV in chronic obstructive pulmonary disease remains controversial. Because pharmacotherapy improves health…”
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Semi‐Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre‐Bronchodilator Forced Expiratory Volume in 1 Second (FEV1) in Uncontrolled Moderate‐To‐Severe Asthma Autor Zhang, Li, Davis, John D., Kanamaluru, Vanaja, Xu, Christine

“…ABSTRACT In this study, we investigated the pharmacokinetic/pharmacodynamic (PK/PD) relationship of dupilumab as an add‐on therapy in the intent‐to‐treat (ITT)…”
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Modified MRC assessment and FEV1.0 can predict frequent acute exacerbation of COPD: An observational prospective cohort study at a single-center in Japan Autor Asai, Nobuhiro, Ohkuni, Yoshihiro, Ohashi, Wataru, Kaneko, Norihiro

“…Acute exacerbation (AE) of chronic obstructive pulmonary disease (COPD) is a fatal event, leading to poor outcomes among COPD patients. However, exact…”
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Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis Autor McCormack, Francis X, Inoue, Yoshikazu, Moss, Joel, Singer, Lianne G, Strange, Charlie, Nakata, Koh, Barker, Alan F, Chapman, Jeffrey T, Brantly, Mark L, Stocks, James M, Brown, Kevin K, Lynch, Joseph P, Goldberg, Hilary J, Young, Lisa R, Kinder, Brent W, Downey, Gregory P, Sullivan, Eugene J, Colby, Thomas V, McKay, Roy T, Cohen, Marsha M, Korbee, Leslie, Taveira-DaSilva, Angelo M, Lee, Hye-Seung, Krischer, Jeffrey P, Trapnell, Bruce C

“…This trial showed that in patients with lymphangioleiomyomatosis (LAM), a progressive, cystic lung disease in women, sirolimus therapy was associated with…”
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A Race-neutral Approach to the Interpretation of Lung Function Measurements Autor Bowerman, Cole, Bhakta, Nirav R, Brazzale, Danny, Cooper, Brendan R, Cooper, Julie, Gochicoa-Rangel, Laura, Haynes, Jeffrey, Kaminsky, David A, Lan, Le Thi Tuyet, Masekela, Refiloe, McCormack, Meredith C, Steenbruggen, Irene, Stanojevic, Sanja

“…The use of self-reported race and ethnicity to interpret lung function measurements has historically assumed that the observed differences in lung function…”
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Risankizumab in Severe Asthma — A Phase 2a, Placebo-Controlled Trial Autor Brightling, Christopher E, Nair, Parameswaran, Cousins, David J, Louis, Renaud, Singh, Dave

“…Although interleukin-23 has been implicated in the pathogenesis of asthma, in this randomized, controlled trial involving adults with severe asthma, inhibition…”
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Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer Autor Cavalheri, Vinicius, Burtin, Chris, Formico, Vittoria R, Nonoyama, Mika L, Jenkins, Sue, Spruit, Martijn A, Hill, Kylie

“…Decreased exercise capacity and health-related quality of life (HRQoL) are common in people following lung resection for non-small cell lung cancer (NSCLC)…”
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Fat mass to fat-free mass ratio and its associations with clinical characteristics in asthma Autor Rugila, Diery Fernandes, Oliveira, Joice Mara, Machado, Felipe Vilaça Cavallari, Correia, Natielly Soares, Puzzi, Vitória Cavalheiro, Passos, Natália Febrini Piassi, Freitas, Patrícia Duarte, Pitta, Fabio, Carvalho, Celso Ricardo Fernandes, Furlanetto, Karina Couto

“…•FM/FFM is associated with different clinical outcomes (factors) in adults with asthma.•Factors are corticosteroids, medication steps, lung function and…”
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Asthma-like Features and Clinical Course of Chronic Obstructive Pulmonary Disease. An Analysis from the Hokkaido COPD Cohort Study Autor Suzuki, Masaru, Makita, Hironi, Konno, Satoshi, Shimizu, Kaoruko, Kimura, Hiroki, Kimura, Hirokazu, Nishimura, Masaharu

“…Some patients with chronic obstructive pulmonary disease (COPD) have asthma-like features, such as significant bronchodilator reversibility, blood…”
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Airwave oscillometry and spirometry in children with asthma or wheeze Autor Gunawardana, Shannon, Tuazon, Mark, Wheatley, Lorna, Cook, James, Harris, Christopher, Greenough, Anne

“…Lung function testing is used in diagnosing asthma and assessing asthma control. Spirometry is most commonly used, but younger children can find performing…”
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Longitudinal assessment of loss and gain of lung function in childhood asthma Autor Mahut, Bruno, Bokov, Plamen, Beydon, Nicole, Delclaux, Christophe

“…The Childhood Asthma Management Program revealed that 25.7% of children with mild to moderate asthma exhibit loss of lung function. The objective was to assess…”
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Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis Autor Chalmers, James D., Burgel, Pierre-Régis, Daley, Charles L., De Soyza, Anthony, Haworth, Charles S., Mauger, David, Loebinger, Michael R., McShane, Pamela J., Ringshausen, Felix C., Blasi, Francesco, Shteinberg, Michal, Mange, Kevin, Teper, Ariel, Fernandez, Carlos, Zambrano, Migdalia, Fan, Chunpeng, Zhang, Xiangmin, Metersky, Mark L.

“…In this randomized trial involving patients with noncystic fibrosis bronchiectasis, the rate of pulmonary exacerbations over a 52-week period was lower with…”
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Associations of dermal diethyl phthalate level with changes in lung function test value mediated by absolute eosinophil count: A panel study of adults in southern Taiwan Autor Wang, Chih-Wen, Wu, Da-Wei, Chen, Szu-Chia, Chen, Huang-Chi, Lin, Hung-Hsun, Su, Hung, Shiea, Jen-taie, Lin, Wen-Yi, Hung, Chih-Hsing, Kuo, Chao-Hung

“…Phthalate concentrations in indoor and outdoor dust are associated with respiratory disease. Both immunoglobulin E (IgE) and eosinophil count are associated…”
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Lung-Function Trajectories and Chronic Obstructive Pulmonary Disease Autor Moran, Mark, Lange, Peter, Celli, Bartolome, Agustí, Alvar

“…To the Editor: In their article on their retrospective analysis of pooled long-term lung-function data, Lange and colleagues (July 9 issue) 1 conclude that “an…”
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Effect of pulmonary exacerbations on long-term lung function decline in cystic fibrosis Autor Waters, Valerie, Stanojevic, Sanja, Atenafu, Eshetu G, Lu, Annie, Yau, Yvonne, Tullis, Elizabeth, Ratjen, Felix

“…It is unknown what proportion of long-term lung function decline in cystic fibrosis (CF) is explained by pulmonary exacerbations. The aim of this study was to…”
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Lung function trajectories in health and disease Autor Agusti, Alvar, Faner, Rosa

“…The normal lung function trajectory from birth to death has three phases: a growth phase (from birth to early adulthood), a plateau phase (that lasts for a few…”
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