Suchergebnisse - "Fitzgerald, Kathryn C"

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis von Absinta, Martina, Maric, Dragan, Gharagozloo, Marjan, Garton, Thomas, Smith, Matthew D., Jin, Jing, Fitzgerald, Kathryn C., Song, Anya, Liu, Poching, Lin, Jing-Ping, Wu, Tianxia, Johnson, Kory R., McGavern, Dorian B., Schafer, Dorothy P., Calabresi, Peter A., Reich, Daniel S.

“… Multiple sclerosis (MS) lesions that do not resolve in the months after they form harbour ongoing demyelination and axon degeneration, and are identifiable in …”
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DeepHarmony: A deep learning approach to contrast harmonization across scanner changes von Dewey, Blake E., Zhao, Can, Reinhold, Jacob C., Carass, Aaron, Fitzgerald, Kathryn C., Sotirchos, Elias S., Saidha, Shiv, Oh, Jiwon, Pham, Dzung L., Calabresi, Peter A., van Zijl, Peter C.M., Prince, Jerry L.

“… Magnetic resonance imaging (MRI) is a flexible medical imaging modality that often lacks reproducibility between protocols and scanners. It has been shown that …”
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Clinical biomarkers differentiate myelitis from vascular and other causes of myelopathy von Barreras, Paula, Fitzgerald, Kathryn C, Mealy, Maureen A, Jimenez, Jorge A, Becker, Daniel, Newsome, Scott D, Levy, Michael, Gailloud, Philippe, Pardo, Carlos A

“… To assess the predictive value of the initial clinical and paraclinical features in the differentiation of inflammatory myelopathies from other causes of …”
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Different risk factors distinguish myalgic encephalomyelitis/chronic fatigue syndrome from severe fatigue von Palacios, Natalia, Molsberry, Samantha, Fitzgerald, Kathryn C., Komaroff, Anthony L.

“… Fatigue is a common reason that patients seek medical care. Only a fraction of these patients meet criteria for myalgic encephalomyelitis/chronic fatigue …”
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Discordant humoral and T cell immune responses to SARS-CoV-2 vaccination in people with multiple sclerosis on anti-CD20 therapy von Gadani, Sachin P., Reyes-Mantilla, Maria, Jank, Larissa, Harris, Samantha, Douglas, Morgan, Smith, Matthew D., Calabresi, Peter A., Mowry, Ellen M., Fitzgerald, Kathryn C., Bhargava, Pavan

“… Sphingosine-1-phosphate receptor (S1P) modulators and anti-CD20 therapies impair humoral responses to SARS-CoV-2 mRNA vaccines. Relatively few studies have …”
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iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu von Morales Pantoja, Itzy E., Smith, Matthew D., Rajbhandari, Labchan, Cheng, Linzhao, Gao, Yongxing, Mahairaki, Vasiliki, Venkatesan, Arun, Calabresi, Peter A., Fitzgerald, Kathryn C., Whartenby, Katharine A.

“… Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS) that results in variable severities of …”
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Hormone therapy use and physical quality of life in postmenopausal women with multiple sclerosis von Bove, Riley, White, Charles C, Fitzgerald, Kathryn C, Chitnis, Tanuja, Chibnik, Lori, Ascherio, Alberto, Munger, Kassandra L

“… To determine the association between hormone therapy (HT) and physical quality of life (QOL) in postmenopausal women with multiple sclerosis (MS). We included …”
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Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigue von Fitzgerald, Kathryn C, Morris, Bridget, Soroosh, Aurash, Balshi, Alexandra, Maher, Dermot, Kaplin, Adam, Nourbakhsh, Bardia

“… Fatigue is the most common symptom of MS and has no effective pharmacotherapy. To determine the tolerability, safety, and efficacy of low-dose ketamine …”
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Intermittent calorie restriction alters T cell subsets and metabolic markers in people with multiple sclerosis von Fitzgerald, Kathryn C., Bhargava, Pavan, Smith, Matthew D., Vizthum, Diane, Henry-Barron, Bobbie, Kornberg, Michael D., Cassard, Sandra D., Kapogiannis, Dimitrios, Sullivan, Patrick, Baer, David J., Calabresi, Peter A., Mowry, Ellen M.

“… Intermittent fasting or calorie restriction (CR) diets provide anti-inflammatory and neuroprotective advantages in models of multiple sclerosis (MS); data in …”
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Intranasal insulin for improving cognitive function in multiple sclerosis von Newsome, Scott D., Fitzgerald, Kathryn C., Hughes, Abbey, Beier, Meghan, Koshorek, Jacqueline, Wang, Yujie, Maldonado, Daniela Pimentel, Shoemaker, Thomas, Malik, Taimur, Bayu, Tarik, Ravenna, Pablo E., Avornu, Ama, Sotirchos, Elias S., Romba, Meghan, Muschelli, John, Brown, Todd T., Calabresi, Peter A., Mowry, Ellen M.

“… Cognitive impairment is common in people with multiple sclerosis (PwMS). There is an urgent need to identify/develop novel therapies that can help cognitive …”
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Intakes of vitamin C and carotenoids and risk of amyotrophic lateral sclerosis: Pooled results from 5 cohort studies von Fitzgerald, Kathryn C., O'Reilly, Éilis J., Fondell, Elinor, Falcone, Guido J., McCullough, Marjorie L., Park, Yikyung, Kolonel, Laurence N., Ascherio, Alberto

“… Objective Prior research has suggested the possible role of oxidative stress in the pathogenesis of amyotrophic lateral sclerosis (ALS). Prospective data …”
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Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism von Fitzgerald, Kathryn C., Smith, Matthew D., Kim, Sol, Sotirchos, Elias S., Kornberg, Michael D., Douglas, Morgan, Nourbakhsh, Bardia, Graves, Jennifer, Rattan, Ramandeep, Poisson, Laila, Cerghet, Mirela, Mowry, Ellen M., Waubant, Emmanuelle, Giri, Shailendra, Calabresi, Peter A., Bhargava, Pavan

“… The circulating metabolome provides unique insights into multiple sclerosis (MS) pathophysiology, but existing studies are relatively small or characterized …”
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Corneal confocal microscopy demonstrates axonal loss in different courses of multiple sclerosis von Petropoulos, Ioannis N., Fitzgerald, Kathryn C., Oakley, Jonathan, Ponirakis, Georgios, Khan, Adnan, Gad, Hoda, George, Pooja, Deleu, Dirk, Canibano, Beatriz G., Akhtar, Naveed, Shuaib, Ashfaq, Own, Ahmed, Malik, Taimur, Russakoff, Daniel B., Mankowski, Joseph L., Misra, Stuti L., McGhee, Charles N. J., Calabresi, Peter, Saidha, Shiv, Kamran, Saadat, Malik, Rayaz A.

“… Axonal loss is the main determinant of disease progression in multiple sclerosis (MS). This study aimed to assess the utility of corneal confocal microscopy …”
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Effect of disease-modifying therapies on subcortical gray matter atrophy in multiple sclerosis von Sotirchos, Elias S, Gonzalez-Caldito, Natalia, Dewey, Blake E, Fitzgerald, Kathryn C, Glaister, Jeffrey, Filippatou, Angeliki, Ogbuokiri, Esther, Feldman, Sydney, Kwakyi, Ohemaa, Risher, Hunter, Crainiceanu, Ciprian, Pham, Dzung L, Van Zijl, Peter C, Mowry, Ellen M, Reich, Daniel S, Prince, Jerry L, Calabresi, Peter A, Saidha, Shiv

“… The effects of disease-modifying therapies (DMTs) on region-specific brain atrophy in multiple sclerosis (MS) are unclear. To determine the effects of higher …”
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Brain and Muscle Metabolic Changes by FDG-PET in Stiff Person Syndrome Spectrum Disorders von Wang, Yujie, Sadaghiani, Mohammad S., Tian, Fan, Fitzgerald, Kathryn C., Solnes, Lilja, Newsome, Scott D.

“… Objective: To report clinical characteristics and fluorodeoxyglucose positron emission tomography (FDG-PET) findings in the brain and muscles of individuals …”
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Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation von Smith, Matthew D., Chamling, Xitiz, Gill, Alexander J., Martinez, Hector, Li, Weifeng, Fitzgerald, Kathryn C., Sotirchos, Elias S., Moroziewicz, Dorota, Bauer, Lauren, Paull, Daniel, Gharagozloo, Marjan, Bhargava, Pavan, Zack, Donald J., Fossati, Valentina, Calabresi, Peter A.

“… Astrocytes are instrumental in maintaining central nervous system (CNS) homeostasis and responding to injury. A major limitation of studying neurodegenerative …”
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Patterns and Predictors of Cognitive Function Among Virally Suppressed Women With HIV von Dastgheyb, Raha M., Buchholz, Alison S., Fitzgerald, Kathryn C., Xu, Yanxun, Williams, Dionna W., Springer, Gayle, Anastos, Kathryn, Gustafson, Deborah R., Spence, Amanda B., Adimora, Adaora A., Waldrop, Drenna, Vance, David E., Milam, Joel, Bolivar, Hector, Weber, Kathleen M., Haughey, Norman J., Maki, Pauline M., Rubin, Leah H.

“… Cognitive impairment remains frequent and heterogeneous in presentation and severity among virally suppressed (VS) women with HIV (WWH). We identified …”
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Associations of sNfL with clinico‐radiological measures in a large MS population von Sotirchos, Elias S., Fitzgerald, Kathryn C., Singh, Carol M., Smith, Matthew D., Reyes‐Mantilla, Maria, Hersh, Carrie M., Hyland, Megan H., Canissario, Ryan, Simmons, Sarah B., Arrambide, Georgina, Montalban, Xavier, Comabella, Manuel, Naismith, Robert T., Qiao, Min, Krupp, Lauren B., Nicholas, Jacqueline A., Akgün, Katja, Ziemssen, Tjalf, Rudick, Richard, Fisher, Elizabeth, Bermel, Robert A., Mowry, Ellen M., Calabresi, Peter A.

“… Objective Evaluation of serum neurofilament light chain (sNfL), measured using high‐throughput assays on widely accessible platforms in large, real‐world MS …”
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Optical Coherence Tomography and Optical Coherence Tomography Angiography Findings After Optic Neuritis in Multiple Sclerosis von Murphy, Olwen C., Kalaitzidis, Grigorios, Vasileiou, Eleni, Filippatou, Angeliki G., Lambe, Jeffrey, Ehrhardt, Henrik, Pellegrini, Nicole, Sotirchos, Elias S., Luciano, Nicholas J., Liu, Yihao, Fitzgerald, Kathryn C., Prince, Jerry L., Calabresi, Peter A., Saidha, Shiv

“… Background: In people with multiple sclerosis (MS), optic neuritis (ON) results in inner retinal layer thinning, and reduced density of the retinal …”
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Retinal measurements predict 10‐year disability in multiple sclerosis von Rothman, Alissa, Murphy, Olwen C., Fitzgerald, Kathryn C., Button, Julia, Gordon‐Lipkin, Eliza, Ratchford, John N., Newsome, Scott D., Mowry, Ellen M., Sotirchos, Elias S., Syc‐Mazurek, Stephanie B., Nguyen, James, Caldito, Natalia Gonzalez, Balcer, Laura J., Frohman, Elliot M., Frohman, Teresa C., Reich, Daniel S., Crainiceanu, Ciprian, Saidha, Shiv, Calabresi, Peter A.

“… Objective Optical coherence tomography (OCT)‐derived measures of the retina correlate with disability and cortical gray matter atrophy in multiple sclerosis …”
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