Výsledky vyhľadávania - "Fasano, Alessio"

Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer Autor Fasano, Alessio

“…The primary functions of the gastrointestinal tract have traditionally been perceived to be limited to the digestion and absorption of nutrients and to…”
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All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases [version 1; peer review: 3 approved] Autor Fasano, Alessio

“…Improved hygiene leading to reduced exposure to microorganisms has been implicated as one possible cause for the recent "epidemic" of chronic inflammatory…”
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Zonulin, regulation of tight junctions, and autoimmune diseases Autor Fasano, Alessio

“…Recent studies indicate that besides digestion and absorption of nutrients and water and electrolytes homeostasis, another key function of the intestine is to…”
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Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases Autor Sturgeon, Craig, Fasano, Alessio

“…Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium with its barrier function is in charge of a tightly controlled…”
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Celiac disease: a comprehensive current review Autor Caio, Giacomo, Volta, Umberto, Sapone, Anna, Leffler, Daniel A., De Giorgio, Roberto, Catassi, Carlo, Fasano, Alessio

“…Background Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and…”
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Zonulin transgenic mice show altered gut permeability and increased morbidity/mortality in the DSS colitis model Autor Sturgeon, Craig, Lan, Jinggang, Fasano, Alessio

“…Increased small intestinal permeability (IP) has been proposed to be an integral element, along with genetic makeup and environmental triggers, in the…”
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Chronic inflammation in the etiology of disease across the life span Autor Furman, David, Campisi, Judith, Verdin, Eric, Carrera-Bastos, Pedro, Targ, Sasha, Franceschi, Claudio, Ferrucci, Luigi, Gilroy, Derek W, Fasano, Alessio, Miller, Gary W, Miller, Andrew H, Mantovani, Alberto, Weyand, Cornelia M, Barzilai, Nir, Goronzy, Jorg J, Rando, Thomas A, Effros, Rita B, Lucia, Alejandro, Kleinstreuer, Nicole, Slavich, George M

“…Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain…”
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Clinical presentation of celiac disease in the pediatric population Autor Fasano, Alessio

“…Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye, and barley) in genetically…”
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children Autor Porritt, Rebecca A., Binek, Aleksandra, Paschold, Lisa, Rivas, Magali Noval, McArdle, Angela, Yonker, Lael M., Alter, Galit, Chandnani, Harsha K., Lopez, Merrick, Fasano, Alessio, Van Eyk, Jennifer E., Binder, Mascha, Arditi, Moshe

“…Multisystem inflammatory syndrome in children (MIS-C) manifests as a severe and uncontrolled inflammatory response with multiorgan involvement, occurring weeks…”
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Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease Autor Freire, Rachel, Ingano, Laura, Serena, Gloria, Cetinbas, Murat, Anselmo, Anthony, Sapone, Anna, Sadreyev, Ruslan I., Fasano, Alessio, Senger, Stefania

“…Celiac disease (CD) is an immune-mediated disorder triggered by gluten exposure. The contribution of the adaptive immune response to CD pathogenesis has been…”
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Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder Autor Needham, Brittany D., Adame, Mark D., Serena, Gloria, Rose, Destanie R., Preston, Gregory M., Conrad, Mary C., Campbell, A. Stewart, Donabedian, David H., Fasano, Alessio, Ashwood, Paul, Mazmanian, Sarkis K.

“…Autism spectrum disorder (ASD) is a neurodevelopmental condition with hallmark behavioral manifestations including impaired social communication and restricted…”
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Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis Autor Yonker, Lael M, Swank, Zoe, Bartsch, Yannic C, Burns, Madeleine D, Kane, Abigail, Boribong, Brittany P, Davis, Jameson P, Loiselle, Maggie, Novak, Tanya, Senussi, Yasmeen, Cheng, Chi-An, Burgess, Eleanor, Edlow, Andrea G, Chou, Janet, Dionne, Audrey, Balaguru, Duraisamy, Lahoud-Rahme, Manuella, Arditi, Moshe, Julg, Boris, Randolph, Adrienne G, Alter, Galit, Fasano, Alessio, Walt, David R

“…Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-targeted mRNA…”
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Spectrum of gluten-related disorders: consensus on new nomenclature and classification Autor Sapone, Anna, Bai, Julio C, Ciacci, Carolina, Dolinsek, Jernej, Green, Peter HR, Hadjivassiliou, Marios, Kaukinen, Katri, Rostami, Kamran, Sanders, David S, Schumann, Michael, Ullrich, Reiner, Villalta, Danilo, Volta, Umberto, Catassi, Carlo, Fasano, Alessio

“…A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10…”
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Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses Autor Yonker, Lael M., Neilan, Anne M., Bartsch, Yannic, Patel, Ankit B., Regan, James, Arya, Puneeta, Gootkind, Elizabeth, Park, Grace, Hardcastle, Margot, St. John, Anita, Appleman, Lori, Chiu, Michelle L., Fialkowski, Allison, De la Flor, Denis, Lima, Rosiane, Bordt, Evan A., Yockey, Laura J., D'Avino, Paolo, Fischinger, Stephanie, Shui, Jessica E., Lerou, Paul H., Bonventre, Joseph V., Yu, Xu G., Ryan, Edward T., Bassett, Ingrid V., Irimia, Daniel, Edlow, Andrea G., Alter, Galit, Li, Jonathan Z., Fasano, Alessio

“…As schools plan for re-opening, understanding the potential role children play in the coronavirus infectious disease 2019 (COVID-19) pandemic and the factors…”
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Gut Permeability and Microbiota in Parkinson’s Disease: Mechanistic Insights and Experimental Therapeutic Strategies Autor Liang, Yicheng, Zhao, Yuhang, Fasano, Alessio, Su, Chien-Wen

“…Globally, Parkinson’s disease (PD) is the neurodegenerative condition with the most rapidly increasing prevalence, and a growing body of evidence associates…”
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Celiac disease diagnosis: simple rules are better than complicated algorithms Autor Catassi, Carlo, Fasano, Alessio

“…Celiac disease is the only treatable autoimmune disease, provided that a correct diagnosis is achieved and a strict, lifelong gluten-free diet is implemented…”
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Autism spectrum disorders pathogenesis: Toward a comprehensive model based on neuroanatomic and neurodevelopment considerations Autor Beopoulos, Athanasios, Géa, Manuel, Fasano, Alessio, Iris, François

“…Autism spectrum disorder (ASD) involves alterations in neural connectivity affecting cortical network organization and excitation to inhibition ratio. It is…”
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Drug Resistance: The Role of Exosomal miRNA in the Microenvironment of Hematopoietic Tumors Autor Cariello, Mariaconcetta, Squilla, Angela, Piacente, Martina, Venutolo, Giorgia, Fasano, Alessio

“…Extracellular vesicles (EVs), including exosomes, have an important role thanks to their ability to communicate and exchange information between tumor cells…”
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Humoral signatures of protective and pathological SARS-CoV-2 infection in children Autor Bartsch, Yannic C., Wang, Chuangqi, Zohar, Tomer, Fischinger, Stephanie, Atyeo, Caroline, Burke, John S., Kang, Jaewon, Edlow, Andrea G., Fasano, Alessio, Baden, Lindsey R., Nilles, Eric J., Woolley, Ann E., Karlson, Elizabeth W., Hopke, Alex R., Irimia, Daniel, Fischer, Eric S., Ryan, Edward T., Charles, Richelle C., Julg, Boris D., Lauffenburger, Douglas A., Yonker, Lael M., Alter, Galit

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic continues to spread relentlessly, associated with a high frequency of respiratory…”
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Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study Autor Kang, Dae-Wook, Adams, James B., Gregory, Ann C., Borody, Thomas, Chittick, Lauren, Fasano, Alessio, Khoruts, Alexander, Geis, Elizabeth, Maldonado, Juan, McDonough-Means, Sharon, Pollard, Elena L., Roux, Simon, Sadowsky, Michael J., Lipson, Karen Schwarzberg, Sullivan, Matthew B., Caporaso, J. Gregory, Krajmalnik-Brown, Rosa

“…Background Autism spectrum disorders (ASD) are complex neurobiological disorders that impair social interactions and communication and lead to restricted,…”
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