Suchergebnisse - "Farrin, Amanda"

The RETurn to work After stroKE (RETAKE) trial: Findings from a mixed-methods process evaluation of the Early Stroke Specialist Vocational Rehabilitation (ESSVR) intervention von Clarke, David James, Powers, Katie, Trusson, Diane, Craven, Kristelle, Phillips, Julie, Holmes, Jain, McKevitt, Christopher, Bowen, Audrey, Watkins, Caroline Leigh, Farrin, Amanda J., Wright-Hughes, Alexandra, Sach, Tracey, Chambers, Rachel, Radford, Kate

“… A key goal for working age stroke survivors is to return to work, yet only around 50% achieve this at 12 months. Currently, there is limited evidence of …”
Volltext

Process evaluation for the STAMINA randomised controlled trial: A protocol von Ibeggazene, Saïd, Reale, Sophie, Scope, Alison, Price, Grace, Sutton, Eileen, Bourke, Liam, Collinson, Michelle, Stokes, Jamie, Steed, Liz, Rosario, Derek, Farrin, Amanda J., Taylor, Steph J.C.

“… STAMINA is a randomised controlled trial of a complex lifestyle intervention incorporating exercise prescription into a prostate cancer care pathway. The …”
Volltext

Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial von Ford, Alexander C, Wright-Hughes, Alexandra, Alderson, Sarah L, Ow, Pei-Loo, Ridd, Matthew J, Foy, Robbie, Bianco, Gina, Bishop, Felicity L, Chaddock, Matthew, Cook, Heather, Cooper, Deborah, Fernandez, Catherine, Guthrie, Elspeth A, Hartley, Suzanne, Herbert, Amy, Howdon, Daniel, Muir, Delia P, Nath, Taposhi, Newman, Sonia, Smith, Thomas, Taylor, Christopher A, Teasdale, Emma J, Thornton, Ruth, Farrin, Amanda J, Everitt, Hazel A, Ford, Alexander C., Wright-Hughes, Alex, Alderson, Sarah L., Ow, Pei-Loo, Ridd, Matthew J., Foy, Robbie, Barratt, Maggie, Bianco, Gina, Bishop, Felicity L., Brindle, Richard, Brown, Sarah, Chaddock, Matthew, Christodoulou, Aimee, Cook, Heather, Cooper, Deborah, Day, Florence, Dowse, Aaron, Durnell, Jill, Emmerson, Jake, Fellows, Alasdair, Fernandez, Catherine, Guthrie, Elspeth A., Hartley, Suzanne, Herbert, Amy, Hindmarch, Damien, Howdon, Daniel, Malik, Aminah, Morris, Tom, Muir, Delia P., Longo, Roberta, Lopes Goncalves Graca, Sandra, Nath, Taposhi, Newman, Sonia, Parker, Catriona, Smith, Thomas, Taylor, Christopher A., Teasdale, Emma J., Thornton, Ruth, Tubeuf, Sandy, West, Amy, Williamson, Emma-Jane, Farrin, Amanda J., Everitt, Hazel A.

“… Most patients with irritable bowel syndrome (IBS) are managed in primary care. When first-line therapies for IBS are ineffective, the UK National Institute for …”
Volltext

Patient risk factors for pressure ulcer development: Systematic review von Coleman, Susanne, Gorecki, Claudia, Nelson, E. Andrea, Closs, S. José, Defloor, Tom, Halfens, Ruud, Farrin, Amanda, Brown, Julia, Schoonhoven, Lisette, Nixon, Jane

“… To identify risk factors independently predictive of pressure ulcer development in adult patient populations? A systematic review of primary research was …”
Volltext

Exploring the perceptions of sedentary behaviour in community-dwelling older adults aged 75 and older: a series of focus group interviews von Tadrous, Ragy, Forster, Anne, Farrin, Amanda, Coventry, Peter A., Clegg, Andrew

“… Background Older adults are the most sedentary and fastest-growing demographic, yet adults aged ≥ 75 years are underrepresented in sedentary behaviour …”
Volltext

Interventions to reduce sedentary behaviour in community-dwelling older adults: a mixed-method review von Tadrous, Ragy, Forster, Anne, Farrin, Amanda, Coventry, Peter, Clegg, Andrew

“… Background Older adults are the fastest-growing and most sedentary group in society. As sedentary behaviour is associated with deleterious health outcomes, …”
Volltext

‘Lessons learned’ from trialists who adapted a complex intervention for remote delivery within a trial as a result of the COVID-19 pandemic: a scoping review von Howes, Ella, Smith, Samuel G., Gillies, Katie, Zhang, Lisa, Farrin, Amanda J.

“… Background During the COVID-19 pandemic, complex interventions being evaluated in randomised controlled trials were often rapidly adapted from in-person to …”
Volltext

Randomised, placebo‐controlled trial and meta‐analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial von Gunn, David, Topan, Rabia, Barnard, Lorna, Fried, Ron, Holloway, Ivana, Brindle, Richard, Corsetti, Maura, Scott, Mark, Farmer, Adam, Kapur, Kapil, Sanders, David, Eugenicos, Maria, Trudgill, Nigel, Whorwell, Peter, Mclaughlin, John, Akbar, Ayesha, Houghton, Lesley, Dinning, Phil G., Aziz, Qasim, Ford, Alexander C., Farrin, Amanda J., Spiller, Robin

“… Summary Background Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS‐D). Aim To conduct a 12‐week parallel group, randomised, …”
Volltext

A new pressure ulcer conceptual framework von Coleman, Susanne, Nixon, Jane, Keen, Justin, Wilson, Lyn, McGinnis, Elizabeth, Dealey, Carol, Stubbs, Nikki, Farrin, Amanda, Dowding, Dawn, Schols, Jos M.G.A., Cuddigan, Janet, Berlowitz, Dan, Jude, Edward, Vowden, Peter, Schoonhoven, Lisette, Bader, Dan L., Gefen, Amit, Oomens, Cees W.J., Nelson, E. Andrea

“… Aim This paper discusses the critical determinants of pressure ulcer development and proposes a new pressure ulcer conceptual framework. Background Recent work …”
Volltext

Safety and efficacy of co-careldopa as an add-on therapy to occupational and physical therapy in patients after stroke (DARS): a randomised, double-blind, placebo-controlled trial von Ford, Gary A, Bhakta, Bipin B, Cozens, Alastair, Hartley, Suzanne, Holloway, Ivana, Meads, David, Pearn, John, Ruddock, Sharon, Sackley, Catherine M, Saloniki, Eirini-Christina, Santorelli, Gillian, Walker, Marion F, Farrin, Amanda J

“… Dopamine is a key modulator of striatal function and learning and might improve motor recovery after stroke. Previous small trials of dopamine agonists after …”
Volltext

An adaptable implementation package targeting evidence-based indicators in primary care: A pragmatic cluster-randomised evaluation von Willis, Thomas A., Collinson, Michelle, Glidewell, Liz, Farrin, Amanda J., Holland, Michael, Meads, David, Hulme, Claire, Petty, Duncan, Alderson, Sarah, Hartley, Suzanne, Vargas-Palacios, Armando, Carder, Paul, Johnson, Stella, Foy, Robbie

“… In primary care, multiple priorities and system pressures make closing the gap between evidence and practice challenging. Most implementation studies focus on …”
Volltext

Predictors of response to low-dose amitriptyline for irritable bowel syndrome and efficacy and tolerability according to subtype: post hoc analyses from the ATLANTIS trial von Wright-Hughes, Alexandra, Ow, Pei-Loo, Alderson, Sarah L, Ridd, Matthew J, Foy, Robbie, Bishop, Felicity L, Chaddock, Matthew, Fernandez, Catherine, Guthrie, Elspeth A, Muir, Delia P, Taylor, Christopher A, Farrin, Amanda J, Everitt, Hazel A, Ford, Alexander C

“… BackgroundLow-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose …”
Volltext

Co-producing an intervention to reduce sedentary behaviour in community-dwelling older adults aged ≥ 75 informed by behaviour change theory von Tadrous, Ragy, Forster, Anne, Farrin, Amanda, Coventry, Peter A., Clegg, Andrew

“… Background Older adults are the fastest-growing and most sedentary group in society. With sedentary behaviour associated with negative health outcomes, …”
Volltext

A hypothesis test of feasibility for external pilot trials assessing recruitment, follow‐up, and adherence rates von Wilson, Duncan T., Brown, Julia, Farrin, Amanda J., Walwyn, Rebecca E. A.

“… The power of a large clinical trial can be adversely affected by low recruitment, follow‐up, and adherence rates. External pilot trials estimate these rates …”
Volltext

Bayesian design and analysis of external pilot trials for complex interventions von Wilson, Duncan T., Wason, James M. S., Brown, Julia, Farrin, Amanda J., Walwyn, Rebecca E. A.

“… External pilot trials of complex interventions are used to help determine if and how a confirmatory trial should be undertaken, providing estimates of …”
Volltext

Brief psychodynamic-interpersonal therapy for adults with a history of self-harm: the SafePIT RCT von Guthrie, Elspeth, Copsey, Bethan, Wright-Hughes, Alexandra, Dowse, Aaron, Bojke, Chris, Mattock, Richard, Day, Florence, Horrocks, Judith, Bianco, Gina, Brennan, Cathy, McAdam, Marsha, Crawford, Michael, Kapur, Navneet, Fernandez, Catherine, Bijsterveld, Petra, Farrin, Amanda

“… There are over 200,000 hospital attendances for self-harm per annum in the United Kingdom at an estimated annual cost of £133-162M. Systematic reviews prior to …”
Volltext

The detection and management of attempted fraud during an online randomised trial von Willis, Thomas A., Wright-Hughes, Alexandra, Skinner, Clare, Farrin, Amanda J., Hartley, Suzanne, Walwyn, Rebecca, Weller, Ana, Althaf, Mohamed, Wilson, Stephanie, Gale, Chris P., Foy, Robbie

“… Background Online studies offer an efficient method of recruiting participants and collecting data. Whilst delivering an online randomised trial, we detected …”
Volltext

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT von Wright-Hughes, Alexandra, Ford, Alexander C, Alderson, Sarah L, Ow, Pei Loo, Ridd, Matthew J, Foy, Robbie, Bishop, Felicity L, Chaddock, Matthew, Cook, Heather, Cooper, Deborah, Fernandez, Catherine, Guthrie, Elspeth A, Hartley, Suzanne, Herbert, Amy, Howdon, Daniel, Muir, Delia P, Newman, Sonia, Taylor, Christopher A, Teasdale, Emma J, Thornton, Ruth, Everitt, Hazel A, Farrin, Amanda J

“… Irritable bowel syndrome, characterised by abdominal pain and a change in stool form or frequency, is most often managed in primary care. When first-line …”
Volltext

A DELPHI study priority setting the remaining challenges for the use of routinely collected data in trials: COMORANT-UK von Williams, Adam D. N., Davies, Gwyneth, Farrin, Amanda J., Mafham, Marion, Robling, Michael, Sydes, Matthew R., Lugg-Widger, Fiona V.

“… Background Researchers are increasingly seeking to use routinely collected data to support clinical trials. This approach has the potential to transform the …”
Volltext

Dementia Care Mapping™ to reduce agitation in care home residents with dementia: the EPIC cluster RCT von Surr, Claire A, Holloway, Ivana, Walwyn, Rebecca Ea, Griffiths, Alys W, Meads, David, Kelley, Rachael, Martin, Adam, McLellan, Vicki, Ballard, Clive, Fossey, Jane, Burnley, Natasha, Chenoweth, Lynn, Creese, Byron, Downs, Murna, Garrod, Lucy, Graham, Elizabeth H, Lilley-Kelley, Amanda, McDermid, Joanne, Millard, Holly, Perfect, Devon, Robinson, Louise, Robinson, Olivia, Shoesmith, Emily, Siddiqi, Najma, Stokes, Graham, Wallace, Daphne, Farrin, Amanda J

“… The quality of care for people with dementia in care homes is of concern. Interventions that can improve care outcomes are required. To investigate the …”
Volltext