Suchergebnisse - "Fallahi, Jafar"

The Role of Tissue Factor In Signaling Pathways of Pathological Conditions and Angiogenesis von Heidari, Zahra, Naeimzadeh, Yasaman, Fallahi, Jafar, Savardashtaki, Amir, Razban, Vahid, Khajeh, Sahar

“… Tissue factor (TF) is an integral transmembrane protein associated with the extrinsic coagulation pathway. TF gene expression is regulated in response to …”
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PyComp: A Versatile Tool for Efficient Data Extraction, Conversion, and Management in High-throughput Virtual Drug Screening von Sisakht, Mohsen, Shahrestanaki, Mohammad Keyvanloo, Fallahi, Jafar, Razban, Vahid

“… Virtual screening (VS) is essential for analyzing potential drug candidates in drug discovery. Often, this involves the conversion of large volumes of compound …”
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Understanding the prion-like behavior of mutant p53 proteins in triple-negative breast cancer pathogenesis: The current therapeutic strategies and future directions von Naeimzadeh, Yasaman, Tajbakhsh, Amir, Fallahi, Jafar

“… Breast cancer (BC) is viewed as a significant public health issue and is the primary cause of cancer-related deaths among women worldwide. Triple-negative …”
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Significant association of hyperandrogenism and insulin resistance with the epigenetic alterations in PPARG1 gene in granulosa cells of PCOS females von Dashti, Zahra, Razban, Vahid, Fallahi, Jafar, Parsanezhad, Mohammad ebrahim, Mehdinejadiani, Shayesteh, Ghasemi, Nasrin

“… Background Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine and metabolic disorders, affecting approximately 15% of females. This …”
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Impact of Various Parameters as Predictors of The Success Rate of In Vitro Fertilization von Dabbagh Rezaeiyeh, Radin, Mehrara, Arian, Mohammad Ali Pour, Amin, Fallahi, Jafar, Forouhari, Sedighe

“… A woman who is infertile is defined as a woman who is unable to conceive after having unprotected sex for more than one year. 20-25% of couples worldwide …”
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The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review von Derakhshan, Zahra, Bahmanpour, Soghra, Alaee, Sanaz, Fallahi, Jafar, Tabei, Seyed Mohammad Bagher

“… Infertility is a global health problem affecting about 15% of all couples, of which 50% are due to male infertility. Although the etiology of infertility is …”
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Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies von Asadi, Maryam, Kiani, Razie, Razban, Vahid, Faraji, Seyed Nooreddin, Ahmadi, Amirhossein, Fallahi, Jafar, Ramezani, Amin, Erfani, Nasrollah

“… CD38 is highly expressed on multiple myeloma (MM) cells and has been successfully targeted by different target therapy methods. This molecule is a critical …”
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Clinical and genetic-epignetic aspects of recurrent hydatidiform mole: A review of literature von Moein-Vaziri, Najmeh, Fallahi, Jafar, Namavar-Jahromi, Bahia, Fardaei, Majid, Momtahan, Mozhdeh, Anvar, Zahra

“… Hydatidiform Mole (HM) is the most common form of Gestational Trophoblastic Disease (GTD), defined by hyper-proliferation of trophoblastic cells. HM is …”
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Founder Effect of KHDC3L, p.M1V Mutation, on Iranian Patients with Recurrent Hydatidiform Moles von Fallahi, Jafar, Anvar, Zahra, Razban, Vahid, Momtahan, Mozhdeh, Namavar-Jahromi, Bahia, Fardaei, Majid

“… Recurrent hydatidiform moles (RHMs) are an unusual pregnancy with at least two molar gestations that are associated with abnormal proliferation of …”
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Identifying a Novel Pathogenic Mutation in Exon 3 of ARID1A Gene in Colon Cancer von Mehran Erfani, Pooneh Mokarram, Maral Mokhtari, Jafar Fallahi

“… ARID1A, a bona fide tumor suppressor, is the third most mutated gene in human colorectal cancer. In this paper, we reported the identification of a novel …”
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A Novel Mutation in NLRP7 Related to Recurrent Hydatidiform Mole and Reproductive Failure von Fallahi, Jafar, Razban, Vahid, Momtahan, Mozhdeh, Akbarzadeh-Jahromi, Mojgan, Namavar-Jahromi, Bahia, Anvar, Zahra, Fardaei, Majid

“… Hydatidiform mole (HM) is an abnormal human pregnancy with excessive trophoblastic proliferation and abnormal embryonic development, dividing into two complete …”
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Novel insight into FCSK‐congenital disorder of glycosylation through a CRISPR‐generated cell model von Fazelzadeh Haghighi, Maryam, Jafari Khamirani, Hossein, Fallahi, Jafar, Monfared, Ali Arabi, Ashrafi Dehkordi, Korosh, Tabei, Seyed Mohammad Bagher

“… Background FCSK‐congenital disorder of glycosylation (FCSK‐CDG) is a recently discovered rare autosomal recessive genetic disorder with defective fucosylation …”
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Using small molecules as a new challenge to redirect metabolic pathway von Morshedi, Dina, Aliakbari, Farhang, Nouri, Hamid Reza, Lotfinia, Majid, Fallahi, Jafar

“… The presence of acetate in the bacterial medium leads to a reduction in the growth rate of cells and recombinant protein production. In this study, three …”
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Exploring the anti-cancer potential of SGLT2 inhibitors in breast cancer treatment in pre-clinical and clinical studies von Naeimzadeh, Yasaman, Tajbakhsh, Amir, Nemati, Mahnaz, Fallahi, Jafar

“… The link between type 2 diabetes mellitus (T2DM) and an increased risk of breast cancer (BC) has prompted the exploration of novel therapeutic strategies …”
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Exploring kartogenin: advances in therapeutics and signaling mechanisms for musculoskeletal regeneration von Kiani, Sareh, Fallahi, Jafar, Tanideh, Nader, Razban, Vahid, Khajeh, Sahar

“… Kartogenin (KGN) is a small synthetic heterocyclic molecule with chondrogenic and chondroprotective effects. Since its discovery, there has been a focus on …”
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A Review on Advanced CRISPR-Based Genome-Editing Tools: Base Editing and Prime Editing von Saber Sichani, Ali, Ranjbar, Maryam, Baneshi, Maryam, Torabi Zadeh, Farid, Fallahi, Jafar

“… In the field of medicine, it is axiomatic that the need of a precise gene-editing tool is critical to employ therapeutic approaches toward pathogenic …”
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Recent advances and applications of peptide–agent conjugates for targeting tumor cells von Alamdari-palangi, Vahab, Jaberi, Khojaste Rahimi, Shahverdi, Mahshid, Naeimzadeh, Yasaman, Tajbakhsh, Amir, Khajeh, Sahar, Razban, Vahid, Fallahi, Jafar

“… Background Cancer, being a complex disease, presents a major challenge for the scientific and medical communities. Peptide therapeutics have played a …”
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Overview of clinical, molecular, and therapeutic features of Niemann–Pick disease (types A, B, and C): Focus on therapeutic approaches von Hosseini, Kamran, Fallahi, Jafar, Razban, Vahid, Sirat, Reyhaneh Zayyani, Varasteh, Mahnaz, Tarhriz, Vahideh

“… Niemann–Pick disease (NPD) is another type of metabolic disorder that is classified as lysosomal storage diseases (LSDs). The main cause of the disease is …”
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Exosome as a target for cancer treatment von Nafar, Samira, Nouri, Negar, Alipour, Maedeh, Fallahi, Jafar, Zare, Fateme, Tabei, Seyed Mohammad Bagher

“… Exosomes are small vesicles covered by a lipid bilayer, ranging in size from 50 nm to 90 nm, secreted by different cell types in the body under normal and …”
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An Investigation into Cell-Free DNA in Different Common Cancers von Nafar, Samira, Hosseini, Kamran, Shokrgozar, Negin, Farahmandi, Amir Yousef, Alamdari-Palangi, Vahab, Saber Sichani, Ali, Fallahi, Jafar

“… Diagnosis is the most important step in different diseases, especially in cancers and blood malignancies. There are different methods in order to better …”
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