Výsledky vyhľadávania - "Falconer, Karolin"

High levels of chronic immune activation in the T-cell compartments of patients coinfected with hepatitis C virus and human immunodeficiency virus type 1 and on highly active antiretroviral therapy are reverted by alpha interferon and ribavirin treatment Autor Gonzalez, Veronica D, Falconer, Karolin, Blom, Kim G, Reichard, Olle, Mørn, Birgitte, Laursen, Alex Lund, Weis, Nina, Alaeus, Annette, Sandberg, Johan K

“…Chronic immune activation is a driver of human immunodeficiency virus type 1 (HIV-1) disease progression. Here, we describe that subjects with chronic…”
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Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection Autor Gorin, Jean-Baptiste, Malone, David F. G., Strunz, Benedikt, Carlsson, Tony, Aleman, Soo, Björkström, Niklas K., Falconer, Karolin, Sandberg, Johan K.

“…Direct-acting antivirals (DAAs) have dramatically improved the management of chronic hepatitis C (CHC). In this study, we investigated the effects of hepatitis…”
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Clinical significance of residual viremia detected by two real-time PCR assays for response-guided therapy of HCV genotype 1 infection Autor Vermehren, Johannes, Aghemo, Alessio, Falconer, Karolin, Susser, Simone, Lunghi, Giovanna, Zeuzem, Stefan, Colombo, Massimo, Weiland, Ola, Sarrazin, Christoph

“…The duration of current standard dual and protease inhibitor-based triple therapies for chronic hepatitis C is determined by assessment of early viral…”
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The future disease burden of hepatitis C virus infection in Sweden and the impact of different treatment strategies Autor Duberg, Ann-Sofi, Blach, Sarah, Falconer, Karolin, Kåberg, Martin, Razavi, Homie, Aleman, Soo

“…AbstractObjective. Recently, new highly effective direct-acting antivirals (DAAs) against hepatitis C virus (HCV) were introduced. Whether these will alleviate…”
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The Dynamic Relationship between Innate Immune Biomarkers and Interferon-Based Treatment Effects and Outcome in Hepatitis C Virus Infection Is Altered by Telaprevir Autor Malone, David F. G., Falconer, Karolin, Weiland, Ola, Sandberg, Johan K.

“…Soluble CD14 (sCD14) and IL-18 are markers and mediators of the innate immune response, and their plasma levels candidate biomarkers of HCV treatment effects…”
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Chronic immune activation in the T cell compartment of HCV/HIV-1 co-infected patients Autor Sandberg, Johan K., Falconer, Karolin, Gonzalez, Veronica D.

“…Activation of innate and adaptive immune mechanisms in response to infection is necessary to control and clear infections. However, chronic immune activation…”
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Long‐Term Study of Hepatitis Delta Virus Infection at Secondary Care Centers: The Impact of Viremia on Liver‐Related Outcomes Autor Kamal, Habiba, Westman, Gabriel, Falconer, Karolin, Duberg, Ann‐Sofi, Weiland, Ola, Haverinen, Susanna, Wejstål, Rune, Carlsson, Tony, Kampmann, Christian, Larsson, Simon B., Björkman, Per, Nystedt, Anders, Cardell, Kristina, Svensson, Stefan, Stenmark, Stephan, Wedemeyer, Heiner, Aleman, Soo

“…Background and Aims Hepatitis delta virus (HDV) infection is associated with fast progression to liver cirrhosis and liver complications. Previous studies…”
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The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education Autor Marquardt, Nicole, Ivarsson, Martin A, Blom, Kim, Gonzalez, Veronica D, Braun, Monika, Falconer, Karolin, Gustafsson, Rasmus, Fogdell-Hahn, Anna, Sandberg, Johan K, Michaëlsson, Jakob

“…NK cells play an important role in the defense against viral infections. However, little is known about the regulation of NK cell responses during the first…”
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Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response Autor Blom, Kim, Braun, Monika, Ivarsson, Martin A, Gonzalez, Veronica D, Falconer, Karolin, Moll, Markus, Ljunggren, Hans-Gustaf, Michaëlsson, Jakob, Sandberg, Johan K

“…The live attenuated yellow fever virus (YFV) 17D vaccine provides a good model to study immune responses to an acute viral infection in humans. We studied the…”
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Long‐Term Study of Hepatitis Delta Virus Infection at Secondary Care Centers: The Impact of Viremia on Liver‐Related Outcomes Autor Kamal, Habiba, Westman, Gabriel, Falconer, Karolin, Duberg, Ann‐Sofi, Weiland, Ola, Haverinen, Susanna, Wejstål, Rune, Carlsson, Tony, Kampmann, Christian, Larsson, Simon B., Björkman, Per, Nystedt, Anders, Cardell, Kristina, Svensson, Stefan, Stenmark, Stephan, Wedemeyer, Heiner, Aleman, Soo

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Uptake of hepatitis C virus treatment in HIV/hepatitis C virus-coinfected patients across Europe in the era of direct-acting antivirals Autor Peters, Lars, Laut, Kamilla, Resnati, Chiara, Del Campo, Santos, Leen, Clifford, Falconer, Karolin, Trofimova, Tatyana, Paduta, Dzmitry, Gatell, Jose, Rauch, Andri, Lacombe, Karine, Domingo, Pere, Chkhartishvili, Nikoloz, Zangerle, Robert, Matulionyte, Raimonda, Mitsura, Viktar, Benfield, Thomas, Zilmer, Kai, Khromova, Irina, Lundgren, Jens, Rockstroh, Jürgen, Mocroft, Amanda

“…To investigate the uptake of hepatitis C virus (HCV) therapy among HIV/HCV-coinfected patients in the pan-European EuroSIDA study between 2011 and 2016. All…”
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Hepatitis delta infection among persons living with HIV in Europe Autor Béguelin, Charles, Boyd, Anders, Falconer, Karolin, Suter‐Riniker, Franziska, Rockstroh, Jürgen K., Mocroft, Amanda, Rauch, Andri, Peters, Lars, Aebi‐Popp, K., Anagnostopoulos, A., Battegay, M., Braun, D. L., Bucher, H. C., Dollenmaier, G., Egger, M., Elzi, L., Hasse, B., Hirsch, H. H., Hoffmann, M., Hösli, I., Keiser, O, Martinetti, G., Metzner, K. J., Pantaleo, G., Perreau, M., Schmid, P., Stöckle, M., Wandeler, G., Kundro, M., Schmied, B., Paduto, D., Clumeck, N., Florence, E, Sedlacek, D., Kronborg, G., Pedersen, C., Ostergaard, L., Nielsen, L. N., Aho, I., Lacombe, K., Degen, O., Hoffmann, C., Stellbrink, H. J., Chkhartishvili, N., Sambatakou, H., Adamis, G., Paissios, N., Gottfredsson, M., Tau, L., Elbirt, D., D’Arminio Monforte, A., Guaraldi, G., Mazeu, I., Mussini, C., Gabbuti, A., Lazzarin, A., Castagna, A., Gianotti, N., Bruun, J., Knysz, B., Bakowska, E., Maciejewska, K., Aksak‐Was, B., Beniowski, M., Kamerys, J., Mansinho, K., Maltez, F., Gusev, D., Khromova, I., Vdoushkina, E., Ranin, J., Laguno, M., Mallolas, J., Rojas, J., Jou, A., Santos, J. R., Sönnerborg, A., Kusejko, K., Cavassini, M., Schmid, P., Kuznetsova, A., Johnson, M. A., Winston, A., Clarke, A., Karpov, I., Losso, M., Lundgren, J., Pradier, C., Chkhartishvili, N., Miró, J. M., Paredes, R., Peters, L., Jaschinski, N., Fursa, O., Raben, D., Kristensen, D., Ahmed, A, Mocroft, A., Reekie, J., Tusch, E. S.

“…Background and Aims A high prevalence of hepatitis delta virus (HDV) infection, the most severe form of viral hepatitis, has been reported among persons living…”
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Clinical Outcomes in Persons Coinfected With Human Immunodeficiency Virus and Hepatitis C Virus: Impact of Hepatitis C Virus Treatment Autor Mocroft, Amanda, Lundgren, Jens, Gerstoft, Jan, Rasmussen, Line D, Bhagani, Sanjay, Aho, Inka, Pradier, Christian, Bogner, Johannes R, Mussini, Christina, Uberti Foppa, Caterina, Maltez, Fernando, Laguno, Montse, Wandeler, Gilles, Falconer, Karolin, Trofimova, Tatyana, Borodulina, Elena, Jevtovic, Djordje, Bakowska, Elzbieta, Kase, Kerstin, Kyselyova, Galina, Haubrich, Richard, Rockstroh, Jürgen K, Peters, Lars

“…A hepatitis C (HCV) cure is associated with changes in lipids and inflammatory biomarkers, but its impact on clinical endpoints among treated human…”
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Effectiveness and Safety of Interferon-Free Direct-Acting Antiviral Hepatitis C Virus Therapy in HIV/Hepatitis C Virus Coinfected Individuals: Results From a Pan-European Study Autor Amele, Sarah, Peters, Lars, Rodger, Alison, Lundgren, Jens, Rockstroh, Jurgen, Matulionyte, Raimonda, Leen, Clifford, Jabłonowska, Elzbieta, Østergaard, Lars, Bhagani, Sanjay, Sarcletti, Mario, Clarke, Amanda, Falconer, Karolin, Wandeler, Gilles, Domingo, Pere, Maltez, Fernando, Zaccarelli, Mauro, Chkhartisvili, Nikoloz, Szlavik, Janos, Stephan, Christoph, Fonquernie, Laurent, Aho, Inka, Mocroft, Amanda

“…To investigate the effectiveness, safety, and reasons for premature discontinuation of direct-acting antivirals (DAAs) in a diverse population of HIV/hepatitis…”
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Expansion of functionally skewed CD56-negative NK cells in chronic hepatitis C virus infection: correlation with outcome of pegylated IFN-alpha and ribavirin treatment Autor Gonzalez, Veronica D, Falconer, Karolin, Björkström, Niklas K, Blom, Kim G, Weiland, Ola, Ljunggren, Hans-Gustaf, Alaeus, Annette, Sandberg, Johan K

“…NK cells are important innate immune effector cells, normally characterized as CD56(+)CD3(-) lymphocytes. In this study, we report that CD56(-)CD16(+) NK cells…”
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Occasional spontaneous clearance of chronic hepatitis C virus in HIV-infected individuals Autor Stenkvist, Jenny, Nyström, Jessica, Falconer, Karolin, Sönnerborg, Anders, Weiland, Ola

“…The IL28B genotype has been found to have a strong influence on spontaneous clearance of acute HCV both in HCV mono- and HIV/ the HCV co-infected patients…”
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IL13R2 expression identifies tissue-resident IL-22-producing PLZF + innate Tcells in the human liver Autor Paquin-Proulx, D, Greenspun, BC, Pasquet, L, Strunz, B, Aleman, S, Falconer, K, Terabe, M, Berzofsky, JA, Sandberg, JK, Melum, E

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IL13Rα2 expression identifies tissue‐resident IL‐22‐producing PLZF+ innate T cells in the human liver Autor Paquin‐Proulx, Dominic, Greenspun, Benjamin C., Pasquet, Lise, Strunz, Benedikt, Aleman, Soo, Falconer, Karolin, Terabe, Masaki, Berzofsky, Jay A., Sandberg, Johan K., Melum, Espen, Nixon, Douglas F., Björkström, Niklas K.

“…Innate lymphocytes are selectively enriched in the liver where they have important roles in liver immunology. Murine studies have shown that type I NKT cells…”
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IL13Rα2 identifies tissue-resident IL-22 producing PLZF+ innate T cells in the human liver Autor Paquin-Proulx, Dominic, Greenspun, Benjamin C., Pasquet, Lise, Strunz, Benedikt, Aleman, Soo, Falconer, Karolin, Terabe, Masaki, Berzofsky, Jay A., Sandberg, Johan K., Melum, Espen, Nixon, Douglas F., Björkström, Niklas K.

“…Innate lymphocytes are selectively enriched in the liver where they have important roles in liver immunology. Murine studies have shown that type I NKT cells…”
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Long-Term Liver-Related Outcomes in Hepatitis B and D Co-Infected Patients in Sweden Autor Kamal, Habiba, Falconer, Karolin, Westman, Gabriel, Duberg, Ann-Sofi, Weiland, Ola R. H. J., Wejstal, Rune, Carlssson, Tony, Kampmann, Christian, Bjoerkman, Per, Nystedt, Anders, Cardell, Kristina, Svensson, Stefan, Stenmark, Stephan, Wedemeyer, Heiner, Aleman, Soo

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