Výsledky vyhledávání - "Epithelial-Mesenchymal Transition"

Pathogenesis of periodontitis – A potential role for epithelial-mesenchymal transition Autor Saliem, Saif S., Bede, Salwan Y., Cooper, Paul R., Abdulkareem, Ali A., Milward, Michael R., Abdullah, Bashar H.

“…Epithelial mesenchymal transition (EMT) is a process comprising cellular and molecular events which result in cells shifting from an epithelial to a mesenchymal phenotype…”
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The epithelial-mesenchymal transition: new insights in signaling, development, and disease Autor Lee, Jonathan M, Dedhar, Shoukat, Kalluri, Raghu, Thompson, Erik W

“… Current interest in this process, which is described as an epithelial-mesenchymal transition (EMT…”
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Multistability in the epithelial-mesenchymal transition network Autor Xin, Ying, Cummins, Bree, Gedeon, Tomáš

“… The number and importance of such states is subject to intense discussion in the epithelial-mesenchymal transition (EMT) community…”
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TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial–mesenchymal transition in Sjögren’s syndrome Autor Sisto, Margherita, Lorusso, Loredana, Ingravallo, Giuseppe, Ribatti, Domenico, Lisi, Sabrina

“…–mesenchymal transition (EMT) in many chronic inflammatory diseases. EMT plays a critical role in the progression of salivary gland (SG…”
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Melanoma cell–derived exosomes promote epithelial–mesenchymal transition in primary melanocytes through paracrine/autocrine signaling in the tumor microenvironment Autor Xiao, Deyi, Barry, Samantha, Kmetz, Daniel, Egger, Michael, Pan, Jianmin, Rai, Shesh N., Qu, Jifu, McMasters, Kelly M., Hao, Hongying

“…•Melanoma cell–derived exosomes promote phenotype switching in primary melanocytes.•MAPK pathway and let-7i were involved in exosome-mediated EMT.•EMT-related…”
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Low Vitamin D Status Is Associated with Epithelial-Mesenchymal Transition in Patients with Chronic Obstructive Pulmonary Disease Autor Fei, Jun, Fu, Lin, Cao, Wei, Hu, Biao, Zhao, Hui, Li, Jia-Bin

“…). However, the mechanisms underlying these effects have largely remained elusive. This study analyzed the correlations among COPD, vitamin D concentration, and epithelial-mesenchymal transition (EMT…”
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TRP channel expression correlates with the epithelial–mesenchymal transition and high-risk endometrial carcinoma Autor Van den Eynde, Charlotte, De Clercq, Katrien, Van Bree, Rieta, Luyten, Katrien, Annibali, Daniela, Amant, Frédéric, Han, Sileny, Van Nieuwenhuysen, Els, Baert, Thaïs, Peeraer, Karen, Voets, Thomas, Van Gorp, Toon, Vriens, Joris

“… However, it is unknown whether TRP channel mRNA expression is subject to the phenotypic switching that occurs during epithelial to mesenchymal transition (EMT…”
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GALNT6 promotes bladder cancer malignancy and immune escape by epithelial-mesenchymal transition and CD8+ T cells Autor Sun, Xiaoxin, Wu, Haotian, Tang, Ling, Al-Danakh, Abdullah, Jian, Yuli, Gong, Li, Li, Congchen, Yu, Xiao, Zeng, Guang, Chen, Qiwei, Yang, Deyong, Wang, Shujing

“… The involvement of GALNT6-mediated aberrant O-glycosylation modification in several malignancies and immune evasion is a subject of speculation…”
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AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial–mesenchymal transition of prostate cancer cells Autor Liu, Zong-cai, Wang, Hong-sheng, Zhang, Ge, Liu, Hao, Chen, Xiao-hui, Zhang, Fan, Chen, Dan-yang, Cai, Shao-hui, Du, Jun

“…Epithelial–mesenchymal transition (EMT) plays a pivotal role in the development of metastatic cancers…”
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KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract Autor Li, Xiao, Chen, Doudou, Ouyang, Bowen, Wang, Shengnan, Li, Yawei, Li, Li, Zhu, Siquan, Zheng, Guangying

“… Krüppel-like factor 5 (KLF5) plays an essential role in migration and the epithelial-mesenchymal transition (EMT…”
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LATS‐regulated nuclear‐cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial–mesenchymal transition Autor Zhang, Feng, Gao, Jie, Liu, Xudong, Sun, Yaohui, Liu, Long, Hu, Bowen, Wang, Zhihui, Shi, Jihua, Guo, Wenzhi, Zhang, Shuijun

“…Abnormal cholesterol synthesis plays a crucial role in the development of hepatocellular carcinoma (HCC). Sterol regulatory element‐binding protein 2 (SREBP2)…”
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IL-6 and TNF-α promote metastasis of lung cancer by inducing epithelial-mesenchymal transition Autor Shang, Guan-Sheng, Liu, Lunxu, Qin, Yi-Wei

“… Thirty serum samples from healthy subjects were selected as controls. Real-time PCR and western blot analysis were used to measure IL-6, TNF-α…”
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Biomarkers of epithelial-mesenchymal transition: E-cadherin and beta-catenin in malignant transformation of oral lesions Autor Yim, Ilena S, Laronde, Denise M

“… E-cadherin and beta-catenin, molecular markers of epithelial-mesenchymal transition (EMT…”
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Gingival tissue samples from periodontitis patients demonstrate epithelial–mesenchymal transition phenotype Autor Saliem, Saif S., Bede, Salwan Y., Abdulkareem, Ali A., Abdullah, Bashar H., Milward, Michael R., Cooper, Paul R.

“…Objective To determine the expression of key epithelial–mesenchymal transition (EMT) markers in gingival tissue samples collected from patients with periodontitis…”
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Eosinophilic esophagitis: Epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment Autor Kagalwalla, Amir F., Akhtar, Noorain, Woodruff, Samantha A., Rea, Bryan A., Masterson, Joanne C., Mukkada, Vincent, Parashette, Kalyan R., Du, Jian, Fillon, Sophie, Protheroe, Cheryl A., Lee, James J., Amsden, Katie, Melin-Aldana, Hector, Capocelli, Kelley E., Furuta, Glenn T., Ackerman, Steven J.

“…) have not been delineated. We sought to explore a role for epithelial mesenchymal transition (EMT) in subjects with EoE and determine whether EMT resolves with treatment…”
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Cigarette smoke-induced alveolar epithelial–mesenchymal transition is mediated by Rac1 activation Autor Shen, Hui-juan, Sun, Yan-hong, Zhang, Shui-juan, Jiang, Jun-xia, Dong, Xin-wei, Jia, Yong-liang, Shen, Jian, Guan, Yan, Zhang, Lin-hui, Li, Fen-fen, Lin, Xi-xi, Wu, Xi-mei, Xie, Qiang-min, Yan, Xiao-feng

“…Epithelial-mesenchymal transition (EMT) is the major pathophysiological process in lung fibrosis observed in chronic obstructive pulmonary disease (COPD) and lung cancer…”
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Circulatory cadmium positively correlates with epithelial-mesenchymal transition in patients with chronic obstructive pulmonary disease Autor Zheng, Ling, Jiang, Ya-Lin, Fei, Jun, Cao, Peng, Zhang, Chen, Xie, Guo-Fang, Wang, Li-Xiang, Cao, Wei, Fu, Lin, Zhao, Hui

“…Environmental cadmium (Cd) exposure can cause several pulmonary diseases. Epithelial-mesenchymal transition (EMT…”
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Epithelial-mesenchymal transition, regulated by β-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis Autor Garcia, Elizabeth, Ladak, Zeenat, Landry, Takaaki, Wollin, Michael, Persad, Amit R. L., Sergi, Consolato M., Huynh, Hien Q., Persad, Rabindranath, Persad, Sujata

“…Eosinophilic Esophagitis (EoE) is an antigen-triggered inflammatory condition of the esophageal lining characterized by eosinophilic infiltration. EoE is…”
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Current insights on extracellular vesicle-mediated glioblastoma progression: Implications in drug resistance and epithelial-mesenchymal transition Autor Mukherjee, Swagatama, Pillai, Prakash P.

“… EVs are shown to have the potential to contribute to the disease progression via mediating drug resistance and epithelial-mesenchymal transition…”
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Role of epithelial–mesenchymal transition factors in the histogenesis of uterine carcinomas Autor Franceschi, Tatiana, Durieux, Emeline, Morel, Anne Pierre, de Saint Hilaire, Pierre, Ray-Coquard, Isabelle, Puisieux, Alain, Devouassoux-Shisheboran, Mojgan

“…). The mechanism by which an EC undergoes dedifferentiation has been the subject of much debate. The epithelial–mesenchymal transition…”
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