Suchergebnisse - "Elding Larsson, Helena"

Effect of screening for type 1 diabetes on early metabolic control: the DiPiS study von Lundgren, Markus, Jonsdottir, Berglind, Elding Larsson, Helena

“… Aims/hypothesis It has been shown that children previously enrolled in follow-up studies have better glycaemic control during the early period after diabetes …”
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One-Hour Oral Glucose Tolerance Tests for the Prediction and Diagnostic Surveillance of Type 1 Diabetes von Simmons, Kimber M, Sosenko, Jay M, Warnock, Megan, Geyer, Susan, Ismail, Heba M, Elding Larsson, Helena, Steck, Andrea K

“… Abstract Context Once islet autoantibody–positive individuals are identified, predicting which individuals are at highest risk for type 1 diabetes (T1D) is …”
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Elevations in blood glucose before and after the appearance of islet autoantibodies in children von Warncke, Katharina, Weiss, Andreas, Achenbach, Peter, von dem Berge, Thekla, Berner, Reinhard, Casteels, Kristina, Groele, Lidia, Hatzikotoulas, Konstantinos, Hommel, Angela, Kordonouri, Olga, Elding Larsson, Helena, Lundgren, Markus, Marcus, Benjamin A., Snape, Matthew D., Szypowska, Agnieszka, Todd, John A., Bonifacio, Ezio, Ziegler, Anette-G.

“… The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell …”
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Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol von Ziegler, Anette-Gabriele, Achenbach, Peter, Berner, Reinhard, Casteels, Kristina, Danne, Thomas, Gündert, Melanie, Hasford, Joerg, Hoffmann, Verena Sophia, Kordonouri, Olga, Lange, Karin, Elding Larsson, Helena, Lundgren, Markus, Snape, Matthew D, Szypowska, Agnieszka, Todd, John A, Bonifacio, Ezio

“… IntroductionThe POInT study, an investigator initiated, randomised, placebo-controlled, double-blind, multicentre primary prevention trial is conducted to …”
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Impaired vibrotactile sense in children and adolescents with type 1 diabetes – Signs of peripheral neuropathy von Ising, Erik, Dahlin, Lars B., Elding Larsson, Helena

“… To investigate whether multi-frequency vibrometry can identify individuals with elevated vibration perception thresholds (VPTs), reflecting impaired …”
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Increased DNA methylation variability in type 1 diabetes across three immune effector cell types von Paul, Dirk S., Teschendorff, Andrew E., Dang, Mary A.N., Lowe, Robert, Hawa, Mohammed I., Ecker, Simone, Beyan, Huriya, Cunningham, Stephanie, Fouts, Alexandra R., Ramelius, Anita, Burden, Frances, Farrow, Samantha, Rowlston, Sophia, Rehnstrom, Karola, Frontini, Mattia, Downes, Kate, Busche, Stephan, Cheung, Warren A., Ge, Bing, Simon, Marie-Michelle, Bujold, David, Kwan, Tony, Bourque, Guillaume, Datta, Avik, Lowy, Ernesto, Clarke, Laura, Flicek, Paul, Libertini, Emanuele, Heath, Simon, Gut, Marta, Gut, Ivo G, Ouwehand, Willem H., Pastinen, Tomi, Soranzo, Nicole, Hofer, Sabine E., Karges, Beate, Meissner, Thomas, Boehm, Bernhard O., Cilio, Corrado, Elding Larsson, Helena, Lernmark, Åke, Steck, Andrea K., Rakyan, Vardhman K., Beck, Stephan, Leslie, R. David

“… The incidence of type 1 diabetes (T1D) has substantially increased over the past decade, suggesting a role for non-genetic factors such as epigenetic …”
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Impaired vibrotactile sense showed no association with insulinoma associated protein 2 and glutamic acid decarboxylase autoantibodies in paediatric type 1 diabetes von Ising, Erik, Dahlin, Lars B., Elding Larsson, Helena

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Factors Associated With the Decline of C-Peptide in a Cohort of Young Children Diagnosed With Type 1 Diabetes von Steck, Andrea K, Liu, Xiang, Krischer, Jeffrey P, Haller, Michael J, Veijola, Riitta, Lundgren, Markus, Ahmed, Simi, Akolkar, Beena, Toppari, Jorma, Hagopian, William A, Rewers, Marian J, Elding Larsson, Helena

“… Abstract Context Understanding factors involved in the rate of C-peptide decline is needed to tailor therapies for type 1 diabetes (T1D). Objective Evaluate …”
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Immunocyte single cell analysis of vaccine‐induced narcolepsy von Lind, Alexander, Salami, Falastin, Landtblom, Anne‐Marie, Palm, Lars, Lernmark, Åke, Adolfsson, Jörgen, Elding Larsson, Helena

“… Increased incidence of narcolepsy type 1 (NT1) was observed following Pandemrix®‐vaccination, initiated as a preventive measure against the 2009 Influenza …”
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Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes von Hendriks, A. Emile J., Marcovecchio, M. Loredana, Besser, Rachel E. J., Bonifacio, Ezio, Casteels, Kristina, Elding Larsson, Helena, Gemulla, Gita, Lundgren, Markus, Kordonouri, Olga, Mallone, Roberto, Pociot, Flemming, Szypowska, Agnieszka, Toppari, Jorma, Ziegler, Anette G., Mathieu, Chantal, Achenbach, Peter, Mathieu, C., Gillard, P., Casteels, K., Overbergh, L., Wallace, C., Evans, M., Thankamony, A., Hendriks, A. E. J., Bruggraber, S., Marcovecchio, M. L., Peakman, M., Tree, T., Richardson, S., Todd, J., Wicker, L., Mander, A., Dayan, C., Alhadj Ali, M., Pieber, T., Eizirik, D., Cnop, M., Brunak, S., Pociot, F., Johannesen, J., Rossing, P., Legido Quigley, C., Mallone, R., Scharfmann, R., Boitard, C., Knip, M., Otonkoski, T., Lahesmaa, R., Oresic, M., Toppari, J., Danne, T., Ziegler, A. G., Achenbach, P., Rodriguez‐Calvo, T., Solimena, M., Bonifacio, E., Speier, S., Holl, R., Dotta, F., Chiarelli, F., Marchetti, P., Bosi, E., Cianfarani, S., Ciampalini, P., Beaufort, C., Dahl‐Jørgensen, K., Skrivarhaug, T., Krogvold, L., Jarosz‐Chobot, P., Battelino, T., Thorens, B., Roep, B., Nikolic, T., Zaldumbide, A., Lernmark, A., Costecalde, G., Strube, T., Schulte, A., Nitsche, A., Peakman, M., Vela, J., Herrath, M., Wesley, J., Napolitano‐Rosen, A., Thomas, M., Schloot, N., Goldfine, A., Waldron‐Lynch, F., Kompa, J., Vedala, A., Hartmann, N., Nicolas, G., Rampelbergh, J., Bovy, N., Dutta, S., Soderberg, J., Ahmed, S., Martin, F., Latres, E., Koralova, A.

“… Background/Aim Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta‐cell antigens, preceding …”
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Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study von Hedlund, Emma, Ludvigsson, Johnny, Elding Larsson, Helena, Forsander, Gun, Ivarsson, Sten, Marcus, Claude, Samuelsson, Ulf, Persson, Martina, Carlsson, Annelie

“… Aim Previous studies have reported an association between month of birth and incidence of type 1 diabetes. Using population‐based data, including almost all …”
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Evaluation of the RSR 3 screen ICA™ and 2 screen ICA™ as screening assays for type 1 diabetes in Sweden von Törn, Carina, Vaziri-Sani, Fariba, Ramelius, Anita, Elding Larsson, Helena, Ivarsson, Sten Anders, Amoroso, Marie, Furmaniak, Jadwiga, Powell, Michael, Smith, Bernard Rees

“… Aim The study aim was to evaluate the RSR 3 Screen ICA™ and 2 Screen ICA™ for detection of islet cell autoimmunity in healthy Swedish subjects and patients …”
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Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children von Elding Larsson, Helena, Lynch, Kristian F., Lönnrot, Maria, Haller, Michael J., Lernmark, Åke, Hagopian, William A., She, Jin-Xiong, Simell, Olli, Toppari, Jorma, Ziegler, Anette-G., Akolkar, Beena, Krischer, Jeffrey P., Rewers, Marian J., Hyöty, Heikki

“… Aims/hypothesis During the A/H1N1 2009 (A/California/04/2009) pandemic, mass vaccination with a squalene-containing vaccine, Pandemrix®, was performed in …”
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Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes von Aydemir, Özkan, Noble, Janelle A, Bailey, Jeffrey A, Lernmark, Åke, Marsh, Patrick, Andersson Svärd, Agnes, Bearoff, Frank, Blankenhorn, Elizabeth P, Mordes, John P

“… Type 1 diabetes (T1D) involves the interaction of multiple gene variants, environmental factors, and immunoregulatory dysfunction. Major T1D genetic risk loci …”
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Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden von Zhao, Lue Ping, Papadopoulos, George K., Moustakas, Antonis K., Bondinas, George P., Carlsson, Annelie, Larsson, Helena Elding, Ludvigsson, Johnny, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Geraghty, Daniel E., Lernmark, Åke

“… HLA-DQ molecules account over 50% genetic risk of type 1 diabetes (T1D), but little is known about associated residues. Through next generation targeted …”
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Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test von Wallenius, Madeleine, Lind, Alexander, Akel, Omar, Karlsson, Emma, Svensson, Markus, Arvidsson, Elin, Ramelius, Anita, Törn, Carina, Palm, Lars, Lernmark, Åke, Elding Larsson, Helena

“… Study objectives: Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was …”
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Vibrotactile Perception in Finger Pulps and in the Sole of the Foot in Healthy Subjects among Children or Adolescents von Dahlin, Lars B., Güner, Nuray, Elding Larsson, Helena, Speidel, Toni

“… To evaluate vibrotactile perception at different frequencies in fingers and in foot in healthy girls and boys. Vibration perception thresholds (VPTs) were …”
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Screening for autoantibody targets in post‐vaccination narcolepsy using proteome arrays von Lind, Alexander, Eriksson, Daniel, Akel, Omar, Ramelius, Anita, Palm, Lars, Lernmark, Åke, Kämpe, Olle, Elding Larsson, Helena, Landegren, Nils

“… Narcolepsy type 1 (NT1) is a chronic sleep disorder caused by a specific loss of hypocretin‐producing neurons. The incidence of NT1 increased in Sweden, …”
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The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study von Warncke, Katharina, Tamura, Roy, Schatz, Desmond A, Veijola, Riitta, Steck, Andrea K, Akolkar, Beena, Hagopian, William, Krischer, Jeffrey P, Lernmark, Åke, Rewers, Marian J, Toppari, Jorma, McIndoe, Richard, Ziegler, Anette-G, Vehik, Kendra, Haller, Michael J, Elding Larsson, Helena

“… Abstract Context The 2 peaks of type 1 diabetes incidence occur during early childhood and puberty. Objective We sought to better understand the relationship …”
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Complete blood counts with red blood cell determinants associate with reduced beta‐cell function in seroconverted Swedish TEDDY children von Salami, Falastin, N.Tamura, Roy, Elding Larsson, Helena, Lernmark, Åke, Törn, Carina

“… Objectives To investigate whether changes in complete blood count (CBC) in islet autoantibody positive children with increased genetic risk for type 1 diabetes …”
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