Suchergebnisse - "Eiriksdottir, Gudny"

Co-regulatory networks of human serum proteins link genetics to disease von Emilsson, Valur, Ilkov, Marjan, Lamb, John R, Finkel, Nancy, Gudmundsson, Elias F, Pitts, Rebecca, Hoover, Heather, Gudmundsdottir, Valborg, Horman, Shane R, Aspelund, Thor, Shu, Le, Trifonov, Vladimir, Sigurdsson, Sigurdur, Manolescu, Andrei, Zhu, Jun, Olafsson, Örn, Jakobsdottir, Johanna, Lesley, Scott A, To, Jeremy, Zhang, Jia, Harris, Tamara B, Launer, Lenore J, Zhang, Bin, Eiriksdottir, Gudny, Yang, Xia, Orth, Anthony P, Jennings, Lori L, Gudnason, Vilmundur

“… Proteins circulating in the blood are critical for age-related disease processes; however, the serum proteome has remained largely unexplored. To this end, …”
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Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies von Harris, William S., Tintle, Nathan L., Imamura, Fumiaki, Qian, Frank, Korat, Andres V. Ardisson, Marklund, Matti, Djoussé, Luc, Bassett, Julie K., Carmichael, Pierre-Hugues, Chen, Yun-Yu, Hirakawa, Yoichiro, Küpers, Leanne K., Laguzzi, Federica, Lankinen, Maria, Murphy, Rachel A., Samieri, Cécilia, Senn, Mackenzie K., Shi, Peilin, Virtanen, Jyrki K., Brouwer, Ingeborg A., Chien, Kuo-Liong, Eiriksdottir, Gudny, Forouhi, Nita G., Geleijnse, Johanna M., Giles, Graham G., Gudnason, Vilmundur, Helmer, Catherine, Hodge, Allison, Jackson, Rebecca, Khaw, Kay-Tee, Laakso, Markku, Lai, Heidi, Laurin, Danielle, Leander, Karin, Lindsay, Joan, Micha, Renata, Mursu, Jaako, Ninomiya, Toshiharu, Post, Wendy, Psaty, Bruce M., Risérus, Ulf, Robinson, Jennifer G., Shadyab, Aladdin H., Snetselaar, Linda, Sala-Vila, Aleix, Sun, Yangbo, Steffen, Lyn M., Tsai, Michael Y., Wareham, Nicholas J., Wood, Alexis C., Wu, Jason H. Y., Hu, Frank, Sun, Qi, Siscovick, David S., Lemaitre, Rozenn N., Mozaffarian, Dariush

“… The health effects of omega-3 fatty acids have been controversial. Here we report the results of a de novo pooled analysis conducted with data from 17 …”
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Cerebral small vessel disease genomics and its implications across the lifespan von Sargurupremraj, Muralidharan, Suzuki, Hideaki, Jian, Xueqiu, Sarnowski, Chloé, Evans, Tavia E., Eiriksdottir, Gudny, Sakaue, Saori, Terzikhan, Natalie, Zhao, Wei, Armstrong, Nicola J., Yanek, Lisa R., Kumar, Rajan B., van den Akker, Erik B., McWhirter, Rebekah E., Trompet, Stella, Mishra, Aniket, Saba, Yasaman, Satizabal, Claudia L., Beaudet, Gregory, Petit, Laurent, Tsuchida, Ami, Schilling, Sabrina, Sigurdsson, Sigurdur, Lewis, Cora E., Lopez, Oscar L., Smith, Jennifer A., Valdés Hernández, Maria C., van der Grond, Jeroen, Wright, Margaret J., Knol, Maria J., Thomson, Russell J., Le Grand, Quentin, Duperron, Marie-Gabrielle, Smith, Albert V., Schreiner, Pamela J., Evans, Denis A., Rotter, Jerome I., Beiser, Alexa S., Maniega, Susana Muñoz, Beekman, Marian, Trollor, Julian, Stott, David J., Vernooij, Meike W., Wittfeld, Katharina, Niessen, Wiro J., Soumaré, Aicha, Sidney, Stephen, Turner, Stephen T., Davies, Gail, Thalamuthu, Anbupalam, Völker, Uwe, van Buchem, Mark A., Dupuis, Josée, Bastin, Mark E., Teumer, Alexander, Amouyel, Philippe, Kwok, John B., Bülow, Robin, Deary, Ian J., Schofield, Peter R., Brodaty, Henry, Jiang, Jiyang, Tabara, Yasuharu, Setoh, Kazuya, Miyamoto, Susumu, Yoshida, Kazumichi, Nagata, Manabu, Matsuda, Fumihiko, Psaty, Bruce M., Bennett, David A., De Jager, Philip L., Mosley, Thomas H., Sachdev, Perminder S., Schmidt, Reinhold, Evangelou, Evangelos, Trégouët, David-Alexandre, Ikram, Mohammad A., DeCarli, Charles, Srikanth, Velandai K., Jukema, J. Wouter, Slagboom, Eline P., Kardia, Sharon L. R., Okada, Yukinori, Mazoyer, Bernard, Wardlaw, Joanna M., Nyquist, Paul A., Mather, Karen A., Grabe, Hans J., Schmidt, Helena, Van Duijn, Cornelia M., Gudnason, Vilmundur, Longstreth, William T., Launer, Lenore J., Lathrop, Mark, Seshadri, Sudha, Tzourio, Christophe, Adams, Hieab H., Matthews, Paul M., Fornage, Myriam, Debette, Stéphanie

“… White matter hyperintensities (WMH) are the most common brain-imaging feature of cerebral small vessel disease (SVD), hypertension being the main known risk …”
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Space and location of cerebral microbleeds, cognitive decline, and dementia in the community von Ding, Jie, Sigurðsson, Sigurður, Jónsson, Pálmi V, Eiriksdottir, Gudny, Meirelles, Osorio, Kjartansson, Olafur, Lopez, Oscar L, van Buchem, Mark A, Gudnason, Vilmundur, Launer, Lenore J

“… To assess the association of the number and anatomic location of cerebral microbleeds (CMBs), visible indicators of microvascular damage on MRI, with incident …”
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Effects of vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes: an individual participant data meta-analysis of randomized controlled trials von Swart, Karin Ma, Lips, Paul, Brouwer, Ingeborg A, Jorde, Rolf, Heymans, Martijn W, Grimnes, Guri, Grübler, Martin R, Gaksch, Martin, Tomaschitz, Andreas, Pilz, Stefan, Eiriksdottir, Gudny, Gudnason, Vilmundur, Wamberg, Louise, Rejnmark, Lars, Sempos, Christopher T, Durazo-Arvizu, Ramón A, Dowling, Kirsten G, Hull, George, Škrabáková, Zuzana, Kiely, Mairead, Cashman, Kevin D, van Schoor, Natasja M

“… Evidence from randomized controlled trials (RCTs) for the causal role of vitamin D on noncommunicable disease outcomes is inconclusive. The aim of this study …”
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Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements von Adalsteinsson, Bjorn T., Gudnason, Haukur, Aspelund, Thor, Harris, Tamara B., Launer, Lenore J., Eiriksdottir, Gudny, Smith, Albert V., Gudnason, Vilmundur

“… Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile, …”
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Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults von Schelbert, Erik B, Cao, Jie J, Sigurdsson, Sigurdur, Aspelund, Thor, Kellman, Peter, Aletras, Anthony H, Dyke, Christopher K, Thorgeirsson, Gudmundur, Eiriksdottir, Gudny, Launer, Lenore J, Gudnason, Vilmundur, Harris, Tamara B, Arai, Andrew E

“… Unrecognized myocardial infarction (MI) is prognostically important. Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI (UMI) …”
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Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study von Sturlaugsdottir, Ran, Aspelund, Thor, Bjornsdottir, Gudlaug, Sigurdsson, Sigurdur, Thorsson, Bolli, Eiriksdottir, Gudny, Gudnason, Vilmundur

“… ObjectiveCarotid plaque and intima-media thickness are non-invasive arterial markers that are used as surrogate end points for cardiovascular disease. The aim …”
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Prevalence of age-related macular degeneration in old persons: Age, Gene/environment Susceptibility Reykjavik Study von Jonasson, Fridbert, Arnarsson, Arsaell, Eiríksdottir, Gudny, Harris, Tamara B, Launer, Lenore J, Meuer, Stacy M, Klein, Barbara E, Klein, Ronald, Gudnason, Vilmundur, Cotch, Mary Frances

“… To describe the prevalence and signs of early and late age-related macular degeneration (AMD) in an old cohort. Population-based cohort study. We included 5272 …”
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Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals von Casanova, Ramon, Varma, Sudhir, Simpson, Brittany, Kim, Min, An, Yang, Saldana, Santiago, Riveros, Carlos, Moscato, Pablo, Griswold, Michael, Sonntag, Denise, Wahrheit, Judith, Klavins, Kristaps, Jonsson, Palmi V, Eiriksdottir, Gudny, Aspelund, Thor, Launer, Lenore J, Gudnason, Vilmundur, Legido Quigley, Cristina, Thambisetty, Madhav

“… Recently, quantitative metabolomics identified a panel of 10 plasma lipids that were highly predictive of conversion to Alzheimer's disease (AD) in cognitively …”
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Hemostatic Factors and Risk of Coronary Heart Disease in General Populations: New Prospective Study and Updated Meta-Analyses von Willeit, Peter, Thompson, Alexander, Aspelund, Thor, Rumley, Ann, Eiriksdottir, Gudny, Lowe, Gordon, Gudnason, Vilmundur, Di Angelantonio, Emanuele

“… Activation of blood coagulation and fibrinolysis may be associated with increased risk of coronary heart disease. We aimed to assess associations of …”
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Mediation analysis of aortic stiffness and renal microvascular function von Woodard, Todd, Sigurdsson, Sigurdur, Gotal, John D, Torjesen, Alyssa A, Inker, Lesley A, Aspelund, Thor, Eiriksdottir, Gudny, Gudnason, Vilmundur, Harris, Tamara B, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F

“… Aortic stiffening, assessed by carotid-femoral pulse wave velocity, is associated with CKD. Transmission of excessive flow pulsatility into the low-impedance …”
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Predictors of carotid plaque progression over a 4-year follow-up in the Reykjavik REFINE-study von Sturlaugsdottir, Ran, Aspelund, Thor, Bjornsdottir, Gudlaug, Sigurdsson, Sigurdur, Thorsson, Bolli, Eiriksdottir, Gudny, Gudnason, Vilmundur

“… Carotid plaque is an arterial marker suggested as a surrogate end point for cardiovascular disease. The aim of this study was to examine the association of …”
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Migraine headache in middle age and late-life brain infarcts von Scher, Ann I, Gudmundsson, Larus S, Sigurdsson, Sigurdur, Ghambaryan, Anna, Aspelund, Thor, Eiriksdottir, Gudny, van Buchem, Mark A, Gudnason, Vilmundur, Launer, Lenore J

“… Migraine is considered to be an episodic condition with no long-term consequences. However, recent studies suggest that migraine attacks may be associated with …”
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Comparison of Handgrip and Leg Extension Strength in Predicting Slow Gait Speed in Older Adults von Fragala, Maren S., Alley, Dawn E., Shardell, Michelle D., Harris, Tamara B., McLean, Robert R., Kiel, Douglas P., Cawthon, Peggy M., Dam, Thuy-Tien L., Ferrucci, Luigi, Guralnik, Jack M., Kritchevsky, Stephen B., Vassileva, Maria T., Gudnason, Vilmunder, Eiriksdottir, Gudny, Koster, Annemarie, Newman, Anne, Siggeirsdottir, Kristin, Satterfield, Suzanne, Studenski, Stephanie A., Kenny, Anne M.

“… Objectives To compare the relative predictive power of handgrip and leg extension strength in predicting slow walking. Design Report of correlative analysis …”
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Frailty and Risk of Cardiovascular Diseases in Older Persons: The Age, Gene/Environment Susceptibility-Reykjavik Study von Veronese, Nicola, Sigeirsdottir, Kristin, Eiriksdottir, Gudny, Marques, Elisa A, Chalhoub, Didier, Phillips, Caroline L, Launer, Lenore J, Maggi, Stefania, Gudnason, Vilmundur, Harris, Tamara B

“… Frailty is a risk factor for cardiovascular diseases (CVD), but the studies available have not considered the presence of subclinical atherosclerotic disease …”
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Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1) von Charidimou, Andreas, Shams, Sara, Romero, Jose R, Ding, Jie, Veltkamp, Roland, Horstmann, Solveig, Eiriksdottir, Gudny, van Buchem, Mark A, Gudnason, Vilmundur, Himali, Jayandra J, Gurol, M Edip, Viswanathan, Anand, Imaizumi, Toshio, Vernooij, Meike W, Seshadri, Sudha, Greenberg, Steven M, Benavente, Oscar R, Launer, Lenore J, Shoamanesh, Ashkan

“… Background Cerebral microbleeds can confer a high risk of intracerebral hemorrhage, ischemic stroke, death and dementia, but estimated risks remain imprecise …”
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Long-Term Interleukin-6 Levels and Subsequent Risk of Coronary Heart Disease: Two New Prospective Studies and a Systematic Review von Danesh, John, Kaptoge, Stephen, Mann, Andrea G, Sarwar, Nadeem, Wood, Angela, Angleman, Sara B, Wensley, Frances, Higgins, Julian P. T, Lennon, Lucy, Eiriksdottir, Gudny, Rumley, Ann, Whincup, Peter H, Lowe, Gordon D. O, Gudnason, Vilmundur

“… The relevance to coronary heart disease (CHD) of cytokines that govern inflammatory cascades, such as interleukin-6 (IL-6), may be underestimated because such …”
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Muscle Quality and Muscle Fat Infiltration in Relation to Incident Mobility Disability and Gait Speed Decline: the Age, Gene/Environment Susceptibility-Reykjavik Study von Reinders, Ilse, Murphy, Rachel A, Koster, Annemarie, Brouwer, Ingeborg A, Visser, Marjolein, Garcia, Melissa E, Launer, Lenore J, Siggeirsdottir, Kristin, Eiriksdottir, Gudny, Jonsson, Palmi V, Gudnason, Vilmundur, Harris, Tamara B

“… Aging is associated with increased risk of reduced mobility. However, data on muscle components in relation to subjective and objective indicators of …”
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C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease von Danesh, John, Wheeler, Jeremy G, Hirschfield, Gideon M, Eda, Shinichi, Eiriksdottir, Gudny, Rumley, Ann, Lowe, Gordon D.O, Pepys, Mark B, Gudnason, Vilmundur

“… This large, prospective study calls into question the value of the C-reactive protein (CRP) concentration in the prediction of coronary events. In contrast to …”
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