Suchergebnisse - "Dupuis, Josée"

Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study von Araki, Tetsuro, Putman, Rachel K., Hatabu, Hiroto, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C., Nishino, Mizuki, Zazueta, Oscar E., Kurugol, Sila, Ross, James C., San José Estépar, Raúl, Schwartz, David A., Rosas, Ivan O., Washko, George R., O’Connor, George T., Hunninghake, Gary M.

“… The relationship between the development and/or progression of interstitial lung abnormalities (ILA) and clinical outcomes has not been previously …”
Volltext

Investigating Associations of Omega-3 Fatty Acids, Lung Function Decline, and Airway Obstruction von Patchen, Bonnie K, Balte, Pallavi, Bartz, Traci M, Barr, R Graham, Fornage, Myriam, Graff, Mariaelisa, Jacobs, Jr, David R, Kalhan, Ravi, Lemaitre, Rozenn N, O'Connor, George, Psaty, Bruce, Seo, Jungkyun, Tsai, Michael Y, Wood, Alexis C, Xu, Hanfei, Zhang, Jingwen, Gharib, Sina A, Manichaikul, Ani, North, Kari, Steffen, Lyn M, Dupuis, Josée, Oelsner, Elizabeth, Hancock, Dana B, Cassano, Patricia A

“… Inflammation contributes to lung function decline and the development of chronic obstructive pulmonary disease. Omega-3 fatty acids have antiinflammatory …”
Weitere Angaben

MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities von Hunninghake, Gary M, Hatabu, Hiroto, Okajima, Yuka, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C, Nishino, Mizuki, Araki, Tetsuro, Zazueta, Oscar E, Kurugol, Sila, Ross, James C, San José Estépar, Raúl, Murphy, Elissa, Steele, Mark P, Loyd, James E, Schwarz, Marvin I, Fingerlin, Tasha E, Rosas, Ivan O, Washko, George R, O'Connor, George T, Schwartz, David A

“… Variants in the gene encoding mucin 5B ( MUC5B ) have been associated with interstitial fibrosis. This study shows a relationship between the presence of the …”
Volltext

Heritability of Atrial Fibrillation von Weng, Lu-Chen, Choi, Seung Hoan, Klarin, Derek, Smith, J Gustav, Loh, Po-Ru, Chaffin, Mark, Roselli, Carolina, Hulme, Olivia L, Lunetta, Kathryn L, Dupuis, Josée, Benjamin, Emelia J, Newton-Cheh, Christopher, Kathiresan, Sekar, Ellinor, Patrick T, Lubitz, Steven A

“… Previous reports have implicated multiple genetic loci associated with AF, but the contributions of genome-wide variation to AF susceptibility have not been …”
Weitere Angaben

Polygenic type 2 diabetes prediction at the limit of common variant detection von Vassy, Jason L, Hivert, Marie-France, Porneala, Bianca, Dauriz, Marco, Florez, Jose C, Dupuis, Josée, Siscovick, David S, Fornage, Myriam, Rasmussen-Torvik, Laura J, Bouchard, Claude, Meigs, James B

“… Genome-wide association studies (GWAS) may have reached their limit of detecting common type 2 diabetes (T2D)-associated genetic variation. We evaluated the …”
Weitere Angaben

Association Between Interstitial Lung Abnormalities and All-Cause Mortality von Putman, Rachel K, Hatabu, Hiroto, Araki, Tetsuro, Gudmundsson, Gunnar, Gao, Wei, Nishino, Mizuki, Okajima, Yuka, Dupuis, Josée, Latourelle, Jeanne C, Cho, Michael H, El-Chemaly, Souheil, Coxson, Harvey O, Celli, Bartolome R, Fernandez, Isis E, Zazueta, Oscar E, Ross, James C, Harmouche, Rola, Estépar, Raúl San José, Diaz, Alejandro A, Sigurdsson, Sigurdur, Gudmundsson, Elías F, Eiríksdottír, Gudny, Aspelund, Thor, Budoff, Matthew J, Kinney, Gregory L, Hokanson, John E, Williams, Michelle C, Murchison, John T, MacNee, William, Hoffmann, Udo, O'Donnell, Christopher J, Launer, Lenore J, Harrris, Tamara B, Gudnason, Vilmundur, Silverman, Edwin K, O'Connor, George T, Washko, George R, Rosas, Ivan O, Hunninghake, Gary M

“… Interstitial lung abnormalities have been associated with lower 6-minute walk distance, diffusion capacity for carbon monoxide, and total lung capacity …”
Weitere Angaben

Leveraging family history in genetic association analyses of binary traits von Zhang, Yixin, Meigs, James B., Liu, Ching-Ti, Dupuis, Josée, Sarnowski, Chloé

“… Background Considering relatives’ health history in logistic regression for case–control genome-wide association studies (CC-GWAS) may provide new information …”
Volltext

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes von Meigs, James B, Shrader, Peter, Sullivan, Lisa M, McAteer, Jarred B, Fox, Caroline S, Dupuis, Josée, Manning, Alisa K, Florez, Jose C, Wilson, Peter W.F, D'Agostino, Ralph B, Cupples, L. Adrienne

“… The authors of this study genotyped single-nucleotide polymorphisms (SNPs) at 18 diabetes-associated loci in participants of the Framingham Offspring Study. A …”
Volltext

Assisted clustering of gene expression data using regulatory data from partially overlapping sets of individuals von Jiang, Wenqing, Joehanes, Roby, Levy, Daniel, O’Connor, George T, Dupuis, Josée

“… Background As omics measurements profiled on different molecular layers are interconnected, integrative approaches that incorporate the regulatory effect from …”
Volltext

Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis von Leong, Aaron, Porneala, Bianca, Dupuis, Josée, Florez, Jose C, Meigs, James B

“… Type 2 diabetes (T2D) is associated with increased mortality in ethnically diverse populations, although the extent to which this association is genetically …”
Weitere Angaben

Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease von Leong, Aaron, Chen, Ji, Wheeler, Eleanor, Hivert, Marie-France, Liu, Ching-Ti, Merino, Jordi, Dupuis, Josée, Tai, E Shyong, Rotter, Jerome I, Florez, Jose C, Barroso, Inês, Meigs, James B

“… Observational studies show that higher hemoglobin A1c (A1C) predicts coronary artery disease (CAD). It remains unclear whether this association is driven …”
Weitere Angaben

Bik promotes proteasomal degradation to control low-grade inflammation von Mebratu, Yohannes A., Jones, Jane T., Liu, Congjian, Negasi, Zerihun H., Rahman, Mizanur, Rojas-Quintero, Joselyn, O’Connor, George T., Gao, Wei, Dupuis, Josée, Cho, Michael H., Litonjua, Augusto A., Randell, Scott, Tesfaigzi, Yohannes

“… Although chronic low-grade inflammation does not cause immediate clinical symptoms, over the longer term, it can enhance other insults or age-dependent damage …”
Volltext

Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study von Haslam, Danielle E., Peloso, Gina M., Herman, Mark A., Dupuis, Josée, Lichtenstein, Alice H., Smith, Caren E., McKeown, Nicola M.

“… Background Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major …”
Volltext

Approximate conditional phenotype analysis based on genome wide association summary statistics von Wu, Peitao, Wang, Biqi, Lubitz, Steven A., Benjamin, Emelia J., Meigs, James B., Dupuis, Josée

“… Because single genetic variants may have pleiotropic effects, one trait can be a confounder in a genome-wide association study (GWAS) that aims to identify …”
Volltext

Structured mating: Patterns and implications von Sebro, Ronnie, Peloso, Gina M., Dupuis, Josée, Risch, Neil J.

“… Genetic similarity of spouses can reflect factors influencing mate choice, such as physical/behavioral characteristics, and patterns of social endogamy. Spouse …”
Volltext

Later midline shift is associated with better post-hospitalization discharge status after large middle cerebral artery stroke von Song, Jonathan J., Stafford, Rebecca A., Pohlmann, Jack E., Kim, Ivy So Yeon, Cheekati, Maanyatha, Dennison, Sydney, Brush, Benjamin, Chatzidakis, Stefanos, Huang, Qiuxi, Smirnakis, Stelios M., Gilmore, Emily J., Mohammed, Shariq, Abdalkader, Mohamad, Benjamin, Emelia J., Dupuis, Josée, Greer, David M., Ong, Charlene J.

“… Space occupying cerebral edema is a feared complication after large ischemic stroke, occurring in up to 30% of patients with middle cerebral artery (MCA) …”
Volltext

Frequency of variants in Mendelian Alzheimer's disease genes within the Alzheimer's Disease Sequencing Project von Wang, Dongyu, Scalici, Alexandra, Wang, Yanbing, Lin, Honghuang, Pitsillides, Achilleas, Heard-Costa, Nancy, Cruchaga, Carlos, Ziegemeier, Ellen, Bis, Joshua C, Fornage, Myriam, Boerwinkle, Eric, De Jager, Philip L, Wijsman, Ellen, Dupuis, Josée, Renton, Alan E, Seshadri, Sudha, Goate, Alison M, DeStefano, Anita L, Peloso, Gina M

“… BackgroundPrior studies examined variants within presenilin-2 ( ), presenilin-1 ( ), and amyloid precursor protein ( ) genes. However, previously-reported …”
Weitere Angaben

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls von Hendricks, Audrey E., Billups, Stephen C., Pike, Hamish N. C., Farooqi, I. Sadaf, Zeggini, Eleftheria, Santorico, Stephanie A., Barroso, Inês, Dupuis, Josée

“… A primary goal of the recent investment in sequencing is to detect novel genetic associations in health and disease improving the development of treatments and …”
Volltext

Association of large core middle cerebral artery stroke and hemorrhagic transformation with hospitalization outcomes von Pohlmann, Jack E., Kim, Ivy So Yeon, Brush, Benjamin, Sambhu, Krishna M., Conti, Lucas, Saglam, Hanife, Milos, Katie, Yu, Lillian, Cronin, Michael F. M., Balogun, Oluwafemi, Chatzidakis, Stefanos, Zhang, Yihan, Trinquart, Ludovic, Huang, Qiuxi, Smirnakis, Stelios M., Benjamin, Emelia J., Dupuis, Josée, Greer, David M., Ong, Charlene J.

“… Historically, investigators have not differentiated between patients with and without hemorrhagic transformation ( HT ) in large core ischemic stroke at risk …”
Volltext

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies von Joehanes, Roby, Zhang, Xiaoling, Huan, Tianxiao, Yao, Chen, Ying, Sai-xia, Nguyen, Quang Tri, Demirkale, Cumhur Yusuf, Feolo, Michael L., Sharopova, Nataliya R., Sturcke, Anne, Schäffer, Alejandro A., Heard-Costa, Nancy, Chen, Han, Liu, Po-ching, Wang, Richard, Woodhouse, Kimberly A., Tanriverdi, Kahraman, Freedman, Jane E., Raghavachari, Nalini, Dupuis, Josée, Johnson, Andrew D., O’Donnell, Christopher J., Levy, Daniel, Munson, Peter J.

“… Background Identification of single nucleotide polymorphisms (SNPs) associated with gene expression levels, known as expression quantitative trait loci …”
Volltext