Výsledky vyhľadávania - "Dudekula, Dawood"

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs Autor Dudekula, Dawood B., Panda, Amaresh C., Grammatikakis, Ioannis, De, Supriyo, Abdelmohsen, Kotb, Gorospe, Myriam

“…Circular RNAs (circRNAs) are widely expressed in animal cells, but their biogenesis and functions are poorly understood. CircRNAs have been shown to act as…”
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Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1 Autor Abdelmohsen, Kotb, Panda, Amaresh C., Munk, Rachel, Grammatikakis, Ioannis, Dudekula, Dawood B., De, Supriyo, Kim, Jiyoung, Noh, Ji Heon, Kim, Kyoung Mi, Martindale, Jennifer L., Gorospe, Myriam

“…HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to…”
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High-purity circular RNA isolation method (RPAD) reveals vast collection of intronic circRNAs Autor Panda, Amaresh C., De, Supriyo, Grammatikakis, Ioannis, Munk, Rachel, Yang, Xiaoling, Piao, Yulan, Dudekula, Dawood B., Abdelmohsen, Kotb, Gorospe, Myriam

“…High-throughput RNA sequencing methods coupled with specialized bioinformatic analyses have recently uncovered tens of thousands of unique circular (circ)RNAs,…”
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HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP Autor Noh, Ji Heon, Kim, Kyoung Mi, Abdelmohsen, Kotb, Yoon, Je-Hyun, Panda, Amaresh C, Munk, Rachel, Kim, Jiyoung, Curtis, Jessica, Moad, Christopher A, Wohler, Christina M, Indig, Fred E, de Paula, Wilson, Dudekula, Dawood B, De, Supriyo, Piao, Yulan, Yang, Xiaoling, Martindale, Jennifer L, de Cabo, Rafael, Gorospe, Myriam

“…Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the mechanisms that mediate their transport to mitochondria are poorly…”
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Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing Autor Kim, Jung-Hyun, Dilthey, Alexander T, Nagaraja, Ramaiah, Lee, Hee-Sheung, Koren, Sergey, Dudekula, Dawood, Wood III, William H, Piao, Yulan, Ogurtsov, Aleksey Y, Utani, Koichi, Noskov, Vladimir N, Shabalina, Svetlana A, Schlessinger, David, Phillippy, Adam M, Larionov, Vladimir

“…Abstract Despite the key role of the human ribosome in protein biosynthesis, little is known about the extent of sequence variation in ribosomal DNA (rDNA) or…”
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Analysis of Circular RNAs Using the Web Tool CircInteractome Autor Panda, Amaresh C, Dudekula, Dawood B, Abdelmohsen, Kotb, Gorospe, Myriam

“…Circular RNAs (circRNAs) are generated through nonlinear back splicing, during which the 5' and 3' ends are covalently joined. Consequently, the lack of free…”
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Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells Autor Akiyama, Tomohiko, Xin, Li, Oda, Mayumi, Sharov, Alexei A., Amano, Misa, Piao, Yulan, Cadet, J. Scotty, Dudekula, Dawood B., Qian, Yong, Wang, Weidong, Ko, Shigeru B. H., Ko, Minoru S. H.

“…Mouse embryonic stem cells (mESCs) have a remarkable capacity to maintain normal genome stability and karyotype in culture. We previously showed that…”
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Classification of benign and malignant subtypes of breast cancer histopathology imaging using hybrid CNN-LSTM based transfer learning Autor Srikantamurthy, Mahati Munikoti, Rallabandi, V. P. Subramanyam, Dudekula, Dawood Babu, Natarajan, Sathishkumar, Park, Junhyung

“…Background Grading of cancer histopathology slides requires more pathologists and expert clinicians as well as it is time consuming to look manually into…”
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Novel RNA-binding activity of MYF5 enhances Ccnd1 / Cyclin D1 mRNA translation during myogenesis Autor Panda, Amaresh C., Abdelmohsen, Kotb, Martindale, Jennifer L., Di Germanio, Clara, Yang, Xiaoling, Grammatikakis, Ioannis, Noh, Ji Heon, Zhang, Yongqing, Lehrmann, Elin, Dudekula, Dawood B., De, Supriyo, Becker, Kevin G., White, Elizabeth J., Wilson, Gerald M., de Cabo, Rafael, Gorospe, Myriam

“…Skeletal muscle contains long multinucleated and contractile structures known as muscle fibers, which arise from the fusion of myoblasts into multinucleated…”
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Age-associated alteration of gene expression patterns in mouse oocytes Autor Hamatani, Toshio, Falco, Geppino, Carter, Mark G, Akutsu, Hidenori, Stagg, Carole A, Sharov, Alexei A, Dudekula, Dawood B, VanBuren, Vincent, Ko, Minoru S H

“…Decreasing oocyte competence with maternal aging is a major factor in human infertility. To investigate the age-dependent molecular changes in a mouse model,…”
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Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines Autor Yamamizu, Kohei, Sharov, Alexei A., Piao, Yulan, Amano, Misa, Yu, Hong, Nishiyama, Akira, Dudekula, Dawood B., Schlessinger, David, Ko, Minoru S. H.

“…Mouse embryonic stem cells (ESCs) can differentiate into a wide range – and possibly all cell types in vitro , and thus provide an ideal platform to study…”
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WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms Autor Lee, Hyung Chul, Jung, Seung Hee, Hwang, Hyun Jung, Kang, Donghee, De, Supriyo, Dudekula, Dawood B., Martindale, Jennifer L., Park, Byungkyu, Park, Seung Kuk, Lee, Eun Kyung, Lee, Jeong-Hwa, Jeong, Sunjoo, Han, Kyungsook, Park, Heon Joo, Ko, Young-Gyu, Gorospe, Myriam, Lee, Jae-Seon

“…RNA-binding proteins (RBPs) are involved in mRNA splicing, maturation, transport, translation, storage and turnover. Here, we identified ACOT7 mRNA as a novel…”
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Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors Autor Nishiyama, Akira, Xin, Li, Sharov, Alexei A, Thomas, Marshall, Mowrer, Gregory, Meyers, Emily, Piao, Yulan, Mehta, Samir, Yee, Sarah, Nakatake, Yuhki, Stagg, Carole, Sharova, Lioudmila, Correa-Cerro, Lina S, Bassey, Uwem, Hoang, Hien, Kim, Eugene, Tapnio, Richard, Qian, Yong, Dudekula, Dawood, Zalzman, Michal, Li, Manxiang, Falco, Geppino, Yang, Hsih-Te, Lee, Sung-Lim, Monti, Manuela, Stanghellini, Ilaria, Islam, Md Nurul, Nagaraja, Ramaiah, Goldberg, Ilya, Wang, Weidong, Longo, Dan L, Schlessinger, David, Ko, Minoru S H

“…To examine transcription factor (TF) network(s), we created mouse ESC lines, in each of which 1 of 50 TFs tagged with a FLAG moiety is inserted into a…”
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A web-based tool for principal component and significance analysis of microarray data Autor Sharov, Alexei A., Dudekula, Dawood B., Ko, Minoru S. H.

“…We have developed a program for microarray data analysis, which features the false discovery rate for testing statistical significance and the principal…”
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) Autor Gerhard, Daniela S, Wagner, Lukas, Feingold, Elise A, Shenmen, Carolyn M, Grouse, Lynette H, Schuler, Greg, Klein, Steven L, Old, Susan, Rasooly, Rebekah, Good, Peter, Guyer, Mark, Peck, Allison M, Derge, Jeffery G, Lipman, David, Collins, Francis S, Jang, Wonhee, Sherry, Steven, Feolo, Mike, Misquitta, Leonie, Lee, Eduardo, Rotmistrovsky, Kirill, Greenhut, Susan F, Schaefer, Carl F, Buetow, Kenneth, Bonner, Tom I, Haussler, David, Kent, Jim, Kiekhaus, Mark, Furey, Terry, Brent, Michael, Prange, Christa, Schreiber, Kirsten, Shapiro, Nicole, Bhat, Narayan K, Hopkins, Ralph F, Hsie, Florence, Driscoll, Tom, Soares, M Bento, Casavant, Tom L, Scheetz, Todd E, Brown-stein, Michael J, Usdin, Ted B, Toshiyuki, Shiraki, Carninci, Piero, Piao, Yulan, Dudekula, Dawood B, Ko, Minoru S H, Kawakami, Koichi, Suzuki, Yutaka, Sugano, Sumio, Gruber, C E, Smith, M R, Simmons, Blake, Moore, Troy, Waterman, Richard, Johnson, Stephen L, Ruan, Yijun, Wei, Chia Lin, Mathavan, S, Gunaratne, Preethi H, Wu, Jiaqian, Garcia, Angela M, Hulyk, Stephen W, Fuh, Edwin, Yuan, Ye, Sneed, Anna, Kowis, Carla, Hodgson, Anne, Muzny, Donna M, McPherson, John, Gibbs, Richard A, Fahey, Jessica, Helton, Erin, Ketteman, Mark, Madan, Anuradha, Rodrigues, Stephanie, Sanchez, Amy, Whiting, Michelle, Madari, Anup, Young, Alice C, Wetherby, Keith D, Granite, Steven J, Kwong, Peggy N, Brinkley, Charles P, Pearson, Russell L, Bouffard, Gerard G, Blakesly, Robert W, Green, Eric D, Dickson, Mark C, Rodriguez, Alex C, Grimwood, Jane, Schmutz, Jeremy, Myers, Richard M, Butterfield, Yaron S N, Griffith, Malachi, Griffith, Obi L, Krzywinski, Martin I, Liao, Nancy, Morin, Ryan, Morrin, Ryan

“…The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource…”
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Identification of Potential Cytochrome P450 3A5 Inhibitors: An Extensive Virtual Screening through Molecular Docking, Negative Image-Based Screening, Machine Learning and Molecular Dynamics Simulation Studies Autor Islam, Md Ataul, Dudekula, Dawood Babu, Rallabandi, V. P. Subramanyam, Srinivasan, Sridhar, Natarajan, Sathishkumar, Chung, Hoyong, Park, Junhyung

“…Cytochrome P450 3A5 (CYP3A5) is one of the crucial CYP family members and has already proven to be an important drug target for cardiovascular diseases. In the…”
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Transcript copy number estimation using a mouse whole-genome oligonucleotide microarray Autor Carter, Mark G, Sharov, Alexei A, VanBuren, Vincent, Dudekula, Dawood B, Carmack, Condie E, Nelson, Charlie, Ko, Minoru SH

“…The ability to quantitatively measure the expression of all genes in a given tissue or cell with a single assay is an exciting promise of gene-expression…”
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Systematic repression of transcription factors reveals limited patterns of gene expression changes in ES cells Autor Nishiyama, Akira, Sharov, Alexei A., Piao, Yulan, Amano, Misa, Amano, Tomokazu, Hoang, Hien G., Binder, Bernard Y., Tapnio, Richard, Bassey, Uwem, Malinou, Justin N., Correa-Cerro, Lina S., Yu, Hong, Xin, Li, Meyers, Emily, Zalzman, Michal, Nakatake, Yuhki, Stagg, Carole, Sharova, Lioudmila, Qian, Yong, Dudekula, Dawood, Sheer, Sarah, Cadet, Jean S., Hirata, Tetsuya, Yang, Hsih-Te, Goldberg, Ilya, Evans, Michele K., Longo, Dan L., Schlessinger, David, Ko, Minoru S. H.

“…Networks of transcription factors (TFs) are thought to determine and maintain the identity of cells. Here we systematically repressed each of 100 TFs with…”
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Screening of β1- and β2-Adrenergic Receptor Modulators through Advanced Pharmacoinformatics and Machine Learning Approaches Autor Islam, Md Ataul, Rallabandi, V. P. Subramanyam, Mohammed, Sameer, Srinivasan, Sridhar, Natarajan, Sathishkumar, Dudekula, Dawood Babu, Park, Junhyung

“…Cardiovascular diseases (CDs) are a major concern in the human race and one of the leading causes of death worldwide. β-Adrenergic receptors (β1-AR and β2-AR)…”
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Generation of mouse ES cell lines engineered for the forced induction of transcription factors Autor Correa-Cerro, Lina S., Piao, Yulan, Sharov, Alexei A., Nishiyama, Akira, Cadet, Jean S., Yu, Hong, Sharova, Lioudmila V., Xin, Li, Hoang, Hien G., Thomas, Marshall, Qian, Yong, Dudekula, Dawood B., Meyers, Emily, Binder, Bernard Y., Mowrer, Gregory, Bassey, Uwem, Longo, Dan L., Schlessinger, David, Ko, Minoru S. H.

“…Here we report the generation and characterization of 84 mouse ES cell lines with doxycycline-controllable transcription factors (TFs) which, together with the…”
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