Výsledky vyhledávání - "Drug-Related Side Effects and Adverse Reactions: economics"

Innovation in Pharmacovigilance: Use of Artificial Intelligence in Adverse Event Case Processing Autor Schmider, Juergen, Kumar, Krishan, LaForest, Chantal, Swankoski, Brian, Naim, Karen, Caubel, Patrick M.

“…Automation of pharmaceutical safety case processing represents a significant opportunity to affect the strongest cost driver for a company's overall…”
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The economic burden of preventable adverse drug reactions: a systematic review of observational studies Autor Formica, D, Sultana, J, Cutroneo, PM, Lucchesi, S, Angelica, R, Crisafulli, S, Ingrasciotta, Y, Salvo, F, Spina, E, Trifirò, G

“…Introduction: Adverse drug reactions (ADRs) are an important cause of morbidity and mortality worldwide. They are associated with healthcare costs due to…”
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National estimates of insulin-related hypoglycemia and errors leading to emergency department visits and hospitalizations Autor Geller, Andrew I, Shehab, Nadine, Lovegrove, Maribeth C, Kegler, Scott R, Weidenbach, Kelly N, Ryan, Gina J, Budnitz, Daniel S

“…Detailed, nationally representative data describing high-risk populations and circumstances involved in insulin-related hypoglycemia and errors (IHEs) can…”
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Implementation of pre‐emptive testing of a pharmacogenomic panel in clinical practice: Where do we stand? Autor Peruzzi, Elena, Roncato, Rossana, De Mattia, Elena, Bignucolo, Alessia, Swen, Jesse J., Guchelaar, Henk‐Jan, Toffoli, Giuseppe, Cecchin, Erika

“…Adverse drug reactions (ADRs) account for a large proportion of hospitalizations among adults and are more common in multimorbid patients, worsening clinical…”
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Incidence and cost of medication harm in older adults following hospital discharge: a multicentre prospective study in the UK Autor Parekh, Nikesh, Ali, Khalid, Stevenson, Jennifer M., Davies, J. Graham, Schiff, Rebekah, Van der Cammen, Tischa, Harchowal, Jatinder, Raftery, James, Rajkumar, Chakravarthi

“…Aims Polypharmacy is increasingly common in older adults, placing them at risk of medication‐related harm (MRH). Patients are particularly vulnerable to…”
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Retrospective Analysis of the Safety and Cost Implications of Pediatric Contrast-Enhanced Ultrasound at a Single Center Autor Yusuf, Gibran T, Sellars, Maria E, Deganello, Annamaria, Cosgrove, David O, Sidhu, Paul S

“…Because of concern over medical ionizing radiation exposure of children, contrast-enhanced ultrasound (CEUS) has generated interest as an inexpensive, ionizing…”
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Economic burden of hospital admissions for adverse drug reactions in France: The IATROSTAT‐ECO study Autor Laroche, Marie‐Laure, Tarbouriech, Noémie, Jai, Taha, Valnet‐Rabier, Marie‐Blanche, Nerich, Virginie

“…Aims Hospitalizations for adverse drug reactions (ADR‐HA) have increased over the last decade, but the impact of ADR‐HA has rarely been evaluated. The aim of…”
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Cost-Effectiveness of Immune Checkpoint Inhibition in BRAF Wild-Type Advanced Melanoma Autor Kohn, Christine G, Zeichner, Simon B, Chen, Qiushi, Montero, Alberto J, Goldstein, Daniel A, Flowers, Christopher R

“…Purpose Patients who are diagnosed with stage IV metastatic melanoma have an estimated 5-year relative survival rate of only 17%. Randomized controlled trials…”
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Reasons for excluding adverse events in cost-effectiveness analyses of vaccines: A survey amongst authors Autor Luyten, Jeroen, van Hoek, Albert Jan

“…Although vaccines must adhere to the strictest safety standards in medicine, adverse events (AE) do occur occasionally. Even when clinically negligeable, these…”
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Medication-related adverse events in health care—what have we learned? A narrative overview of the current knowledge Autor Laatikainen, O., Sneck, S., Turpeinen, M.

“…Purpose Although medication-related adverse events (MRAEs) in health care are vastly studied, high heterogeneity in study results complicates the…”
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Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity Autor Fragoulakis, Vasileios, Roncato, Rossana, Fratte, Chiara Dalle, Ecca, Fabrizio, Bartsakoulia, Marina, Innocenti, Federico, Toffoli, Giuseppe, Cecchin, Erika, Patrinos, George P, Mitropoulou, Christina

“…Fluoropyrimidines (FLs) have been widely used for more than 60 years against a range of solid tumors and still remains the cornerstone for the treatment of…”
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New estimates of the costs of adverse events in patients with cancer Autor Patel, Achal, Schuldt, Robert, Sussell, Jesse

“…The cost of adverse events (AEs) is a critical component of healthcare economic models for cancer treatment; however, few comprehensive estimates of these…”
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A Systematic Review of Economic Evaluations of Pharmacogenetic Testing for Prevention of Adverse Drug Reactions Autor Plumpton, Catrin O., Roberts, Daniel, Pirmohamed, Munir, Hughes, Dyfrig A.

“…Background Pharmacogenetics offers the potential to improve health outcomes by identifying individuals who are at greater risk of harm from certain medicines…”
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Incidence of Exposure of Patients in the United States to Multiple Drugs for Which Pharmacogenomic Guidelines Are Available Autor Samwald, Matthias, Xu, Hong, Blagec, Kathrin, Empey, Philip E., Malone, Daniel C., Ahmed, Seid Mussa, Ryan, Patrick, Hofer, Sebastian, Boyce, Richard D.

“…Pre-emptive pharmacogenomic (PGx) testing of a panel of genes may be easier to implement and more cost-effective than reactive pharmacogenomic testing if a…”
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Methods for Including Adverse Events in Economic Evaluations: Suggestions for Improvement Autor Ghabri, Salah, Dawoud, Dalia, Drummond, Michael

“…Inclusion of relevant effectiveness and safety outcomes in economic evaluation of health technologies is required to aid efficient healthcare decisions. Our…”
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Prevention of Hospital-Acquired Adverse Drug Reactions in Older People Using Screening Tool of Older Persons' Prescriptions and Screening Tool to Alert to Right Treatment Criteria: A Cluster Randomized Controlled Trial Autor O'Connor, Marie N., O'Sullivan, David, Gallagher, Paul F., Eustace, Joseph, Byrne, Stephen, O'Mahony, Denis

“…Objectives To determine whether use of the Screening Tool of Older Persons' Prescriptions (STOPP) and Screening Tool to Alert to Right Treatment (START)…”
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Drug safety sciences and the bottleneck in drug development Autor Watkins, P B

“…During a recent review of a new drug application for treatment of a chronic disease, US Food and Drug Administration (FDA) regulators agreed with the sponsor's…”
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Clinical and economic impact of pharmacist interventions to identify drug-related problems in multidisciplinary cancer care: a prospective trial Autor Giraud, Jean-Stéphane, Korb-Savoldelli, Virginie, Perrin, Germain, Jouinot, Anne, Sabatier, Brigitte, Batista, Rui, Ribault, Matthieu, De Percin, Sixtine, Villeminey, Clémentine, Videau, Margaux, Blanchet, Benoit, Goldwasser, Francois, Degrassat-Theas, Albane, Thomas-Schoemann, Audrey

“…Abstract Background The prescription of antitumor drugs has often been associated with drug-related problems. Pretherapeutic multidisciplinary risk assessment…”
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Clinical pharmacist‐led costs optimization in ischaemic stroke care: A diagnosis‐related groups‐based intervention study Autor Li, Yun, Li, Xianlin, Guo, Haitao, Zhang, Jin, Zheng, Xiaojun

“…This study aimed to evaluate the impact of clinical pharmacists' intervention on drug cost optimization for ischaemic stroke inpatients under the…”
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Cost effectiveness analysis of HLA-B58:01 genotyping prior to initiation of allopurinol for gout Autor Plumpton, Catrin O, Alfirevic, Ana, Pirmohamed, Munir, Hughes, Dyfrig A

“…To determine whether prospective testing for HLA-B*58:01, as a strategy to prevent serious adverse reactions to allopurinol in patients with gout, is…”
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