Search Results - "Drug-Related Side Effects and Adverse Reactions"

Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by Haanen, J B A G, Carbonnel, F, Robert, C, Kerr, K M, Peters, S, Larkin, J, Jordan, K

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Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report by Borisov, Sergey, Danila, Edvardas, Maryandyshev, Andrei, Dalcolmo, Margareth, Miliauskas, Skaidrius, Kuksa, Liga, Manga, Selene, Skrahina, Alena, Diktanas, Saulius, Codecasa, Luigi Ruffo, Aleksa, Alena, Bruchfeld, Judith, Koleva, Antoniya, Piubello, Alberto, Udwadia, Zarir Farokh, Akkerman, Onno W, Belilovski, Evgeny, Bernal, Enrique, Boeree, Martin J, Cadiñanos Loidi, Julen, Cai, Qingshan, Cebrian Gallardo, Jose Joaquín, Dara, Masoud, Davidavičienė, Edita, Forsman, Lina Davies, De Los Rios, Jorge, Denholm, Justin, Drakšienė, Jacinta, Duarte, Raquel, Elamin, Seifeldin Eltaeb, Escobar Salinas, Nadia, Ferrarese, Maurizio, Filippov, Alexey, Garcia, Ana, García-García, José-María, Gaudiesiute, Ieva, Gavazova, Blagovesta, Gayoso, Regina, Gomez Rosso, Roscio, Gruslys, Vygantas, Gualano, Gina, Hoefsloot, Wouter, Jonsson, Jerker, Khimova, Elena, Kunst, Heinke, Laniado-Laborín, Rafael, Li, Yang, Magis-Escurra, Cecile, Manfrin, Vinicio, Marchese, Valentina, Martínez Robles, Elena, Matteelli, Alberto, Mazza-Stalder, Jesica, Moschos, Charalampos, Muñoz-Torrico, Marcela, Mustafa Hamdan, Hamdan, Nakčerienė, Birutė, Nicod, Laurent, Nieto Marcos, Magnolia, Palmero, Domingo Juan, Palmieri, Fabrizio, Papavasileiou, Apostolos, Payen, Marie-Christine, Pontarelli, Agostina, Quirós, Sarai, Rendon, Adrian, Saderi, Laura, Šmite, Agnese, Solovic, Ivan, Souleymane, Mahamadou Bassirou, Tadolini, Marina, van den Boom, Martin, Vescovo, Marisa, Viggiani, Pietro, Yedilbayev, Askar, Zablockis, Rolandas, Zhurkin, Dmitry, Zignol, Matteo, Visca, Dina, Spanevello, Antonio, Caminero, José A, Alffenaar, Jan-Willem, Tiberi, Simon, Centis, Rosella, D'Ambrosio, Lia, Pontali, Emanuele, Sotgiu, Giovanni, Migliori, Giovanni Battista

“…The World Health Organization (WHO) recommends that countries implement pharmacovigilance and collect information on active drug safety monitoring (aDSM) and…”
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Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline by Santomasso, Bianca D, Nastoupil, Loretta J, Adkins, Sherry, Lacchetti, Christina, Schneider, Bryan J, Anadkat, Milan, Atkins, Michael B, Brassil, Kelly J, Caterino, Jeffrey M, Chau, Ian, Davies, Marianne J, Ernstoff, Marc S, Fecher, Leslie, Funchain, Pauline, Jaiyesimi, Ishmael, Mammen, Jennifer S, Naidoo, Jarushka, Naing, Aung, Phillips, Tanyanika, Porter, Laura D, Reichner, Cristina A, Seigel, Carole, Song, Jung-Min, Spira, Alexander, Suarez-Almazor, Maria, Swami, Umang, Thompson, John A, Vikas, Praveen, Wang, Yinghong, Weber, Jeffrey S, Bollin, Kathryn, Ghosh, Monalisa

“…To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events (irAEs) in patients treated with…”
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New therapeutic perspectives to manage refractory immune checkpoint-related toxicities by Martins, Filipe, Sykiotis, Gerasimos P, Maillard, Michel, Fraga, Montserrat, Ribi, Camillo, Kuntzer, Thierry, Michielin, Olivier, Peters, Solange, Coukos, Georges, Spertini, Francois, Thompson, John A, Obeid, Michel

“…Immune checkpoint inhibitors are reshaping the prognosis of many cancer and are progressively becoming the standard of care in the treatment of many tumour…”
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The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity: Executive Summary 2017 by Neal, Joseph M., Barrington, Michael J., Fettiplace, Michael R., Gitman, Marina, Memtsoudis, Stavros G., Mörwald, Eva E., Rubin, Daniel S., Weinberg, Guy

“…AbstractThe American Society of Regional Anesthesia and Pain Medicine's Third Practice Advisory on local anesthetic systemic toxicity is an interim update from…”
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Drug allergy: an updated practice parameter

“…Adverse drug reactions (ADRs) result in major health problems in the United States in both the inpatient and outpatient setting. ADRs are broadly categorized…”
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Interleukin-6 blockade for prophylaxis and management of immune-related adverse events in cancer immunotherapy by Dimitriou, Florentia, Hogan, Sabrina, Menzies, Alexander M., Dummer, Reinhard, Long, Georgina V.

“…Immune checkpoint inhibitors (ICIs) have activity across many tumor types, but activation of the immune system may also lead to significant, often…”
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Tumor Mutational Burden, Toxicity, and Response of Immune Checkpoint Inhibitors Targeting PD(L)1, CTLA-4, and Combination: A Meta-regression Analysis by Osipov, Arsen, Lim, Su Jin, Popovic, Aleksandra, Azad, Nilofer S, Laheru, Daniel A, Zheng, Lei, Jaffee, Elizabeth M, Wang, Hao, Yarchoan, Mark

“…Tumor mutational burden (TMB) has emerged as a potential predictive biomarker for clinical response to ICI therapy, but whether TMB also predicts toxicity…”
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Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance by Martins, Filipe, Sofiya, Latifyan, Sykiotis, Gerasimos P, Lamine, Faiza, Maillard, Michel, Fraga, Montserrat, Shabafrouz, Keyvan, Ribi, Camillo, Cairoli, Anne, Guex-Crosier, Yan, Kuntzer, Thierry, Michielin, Olivier, Peters, Solange, Coukos, Georges, Spertini, Francois, Thompson, John A, Obeid, Michel

“…Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4 (CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell…”
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Association of Adverse Events With Antibiotic Use in Hospitalized Patients by Tamma, Pranita D, Avdic, Edina, Li, David X, Dzintars, Kathryn, Cosgrove, Sara E

“…Estimates of the incidence of overall antibiotic-associated adverse drug events (ADEs) in hospitalized patients are generally unavailable. To describe the…”
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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial by Park, Keunchil, Tan, Eng-Huat, O'Byrne, Ken, Zhang, Li, Boyer, Michael, Mok, Tony, Hirsh, Vera, Yang, James Chih-Hsin, Lee, Ki Hyeong, Lu, Shun, Shi, Yuankai, Kim, Sang-We, Laskin, Janessa, Kim, Dong-Wan, Arvis, Catherine Dubos, Kölbeck, Karl, Laurie, Scott A, Tsai, Chun-Ming, Shahidi, Mehdi, Kim, Miyoung, Massey, Dan, Zazulina, Victoria, Paz-Ares, Luis

“…The irreversible ErbB family blocker afatinib and the reversible EGFR tyrosine kinase inhibitor gefitinib are approved for first-line treatment of EGFR…”
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Incidence and management of toxicity associated with ibrutinib and idelalisib: a practical approach by de Weerdt, Iris, Koopmans, Suzanne M., Kater, Arnon P., van Gelder, Michel

“…The use of novel B-cell receptor signaling inhibitors results in high response rates and long progression-free survival in patients with indolent B-cell…”
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Adverse Drug Reactions in Patients with CKD by Laville, Solène M, Gras-Champel, Valérie, Moragny, Julien, Metzger, Marie, Jacquelinet, Christian, Combe, Christian, Fouque, Denis, Laville, Maurice, Frimat, Luc, Robinson, Bruce M, Stengel, Bénédicte, Massy, Ziad A, Liabeuf, Sophie

“…Little is known about the burden of adverse drug reactions in CKD. We estimated the incidence of overall and serious adverse drug reactions and assessed the…”
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Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study by Waljee, Akbar K, Rogers, Mary A M, Lin, Paul, Singal, Amit G, Stein, Joshua D, Marks, Rory M, Ayanian, John Z, Nallamothu, Brahmajee K

“…Objective To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism,…”
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Intensive Treatment and Severe Hypoglycemia Among Adults With Type 2 Diabetes by McCoy, Rozalina G, Lipska, Kasia J, Yao, Xiaoxi, Ross, Joseph S, Montori, Victor M, Shah, Nilay D

“…Intensive glucose-lowering treatment among patients with non-insulin-requiring type 2 diabetes may increase the risk of hypoglycemia. To estimate the…”
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Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxicity for Use in Immuno-Oncology by Autio, Karen A, Boni, Valentina, Humphrey, Rachel W, Naing, Aung

“…The deep and durable antitumor effects of antibody-based immunotherapies such as immune checkpoint inhibitors (ICIs) have revolutionized oncology and…”
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Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies by Lanvers-Kaminsky, C, Zehnhoff-Dinnesen, Ag Am, Parfitt, R, Ciarimboli, G

“…Drug ototoxicity limits the quality of life of patients after treatment, having serious consequences, especially for psychosocial development of children…”
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Blood Pressure, Antihypertensive Polypharmacy, Frailty, and Risk for Serious Fall Injuries Among Older Treated Adults With Hypertension by Bromfield, Samantha G, Ngameni, Cedric-Anthony, Colantonio, Lisandro D, Bowling, C Barrett, Shimbo, Daichi, Reynolds, Kristi, Safford, Monika M, Banach, Maciej, Toth, Peter P, Muntner, Paul

“…Antihypertensive medication and low systolic blood pressure (BP) and diastolic BP have been associated with an increased falls risk in some studies. Many older…”
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Adverse Events and Factors Associated with Potentially Avoidable Use of General Anesthesia in Cesarean Deliveries by Guglielminotti, Jean, Landau, Ruth, Li, Guohua

“…Compared with neuraxial anesthesia, general anesthesia for cesarean delivery is associated with increased risk of maternal adverse events. Reducing avoidable…”
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Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic by Mendrick, Donna L, Diehl, Anna Mae, Topor, Lisa S, Dietert, Rodney R, Will, Yvonne, La Merrill, Michele A, Bouret, Sebastien, Varma, Vijayalaskshmi, Hastings, Kenneth L, Schug, Thaddeus T, Emeigh Hart, Susan G, Burleson, Florence G

“…Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic, a Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held…”
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