Suchergebnisse - "Drug Delivery Systems/methods"

Ocular Drug Delivery: Present Innovations and Future Challenges von Gote, Vrinda, Sikder, Sadia, Sicotte, Jeff, Pal, Dhananjay

“… Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery scientists due to the presence of various anatomic and physiologic …”
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Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades? von Vallet-Regí, María, Schüth, Ferdi, Lozano, Daniel, Colilla, Montserrat, Manzano, Miguel

“… The present review details a chronological description of the events that took place during the development of mesoporous materials, their different synthetic …”
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Decorated bacteria and the application in drug delivery von Wu, Feng, Liu, Jinyao

“… [Display omitted] The use of living bacteria either as therapeutic agents or drug carriers has shown great potential in treating a multitude of intractable …”
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G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs? von Sriram, Krishna, Insel, Paul A

“… Estimates vary regarding the number of G protein-coupled receptors (GPCRs), the largest family of membrane receptors that are targeted by approved drugs, and …”
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Nose-to-Brain Delivery von Wang, Zian, Xiong, Guojun, Tsang, Wai Chun, Schätzlein, Andreas G, Uchegbu, Ijeoma F

“… The global prevalence of neurologic disorders is rising, and yet we are still unable to deliver most drug molecules, in therapeutic quantities, to the brain …”
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TEMPORARY REMOVAL: Effects of flow lamination on aerosolized drug delivery through spatial barriers von Haroutunian, GGreg, Tsaghikian, Ashot, Soherwardy, Amenah, Zheng, Haiyan, Mosoian, Arevik

“… The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the …”
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Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties von Subrizi, Astrid, del Amo, Eva M., Korzhikov-Vlakh, Viktor, Tennikova, Tatiana, Ruponen, Marika, Urtti, Arto

“… •Ocular drug delivery is a field in which regular ADME tools are not useful.•Pharmacokinetics based dosing aid for ocular drug delivery is …”
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Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms von Zi, Yixuan, Yang, Kaiyun, He, Jianhua, Wu, Zimei, Liu, Jianping, Zhang, Wenli

“… [Display omitted] The Enhanced Permeability and Retention (EPR) effect has been recognized as the central paradigm in tumor-targeted delivery in the last …”
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Targeting drugs to tumours using cell membrane-coated nanoparticles von Fang, Ronnie H, Gao, Weiwei, Zhang, Liangfang

“… Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-specific nature, causing harm to non-malignant tissues. Over the past …”
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Extracellular vesicles for drug delivery von Vader, Pieter, Mol, Emma A., Pasterkamp, Gerard, Schiffelers, Raymond M.

“… Extracellular vesicles (EVs) are cell-derived membrane vesicles, and represent an endogenous mechanism for intercellular communication. Since the discovery …”
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ExosomesNature’s Lipid Nanoparticles, a Rising Star in Drug Delivery and Diagnostics von Tenchov, Rumiana, Sasso, Janet M., Wang, Xinmei, Liaw, Wen-Shing, Chen, Chun-An, Zhou, Qiongqiong Angela

“… Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer membrane and secreted by most eukaryotic cells. They represent a route …”
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Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications von Yang, Chunhao, Xue, Yunxin, Duan, Yu, Mao, Chun, Wan, Mimi

“… Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are intracellular in origin and have the same composition as their parent …”
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Interpreting non-linear drug diffusion data: Utilizing Korsmeyer-Peppas model to study drug release from liposomes von Wu, Iren Yeeling, Bala, Sonali, Škalko-Basnet, Nataša, di Cagno, Massimiliano Pio

“… The aim of this work was to clarify the dynamics behind the influence of ionic strength on the changes in drug release from large unilamellar vesicles (LUVs) …”
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Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies von Escudé Martinez de Castilla, Pol, Tong, Lingjun, Huang, Chenyuan, Sofias, Alexandros Marios, Pastorin, Giorgia, Chen, Xiaoyuan, Storm, Gert, Schiffelers, Raymond M., Wang, Jiong-Wei

“… [Display omitted] •Pros and cons and recent trends of EVs for drug delivery in animal disease models.•Quantitative analysis of the key parameters of EVs as …”
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Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come von Yingchoncharoen, Phatsapong, Kalinowski, Danuta S, Richardson, Des R

“… Cancer is a leading cause of death in many countries around the world. However, the efficacy of current standard treatments for a variety of cancers is …”
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Organic Bioelectronics: Bridging the Signaling Gap between Biology and Technology von Simon, Daniel T, Gabrielsson, Erik O, Tybrandt, Klas, Berggren, Magnus

“… The electronics surrounding us in our daily lives rely almost exclusively on electrons as the dominant charge carrier. In stark contrast, biological systems …”
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Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities von Nagelkerke, Anika, Ojansivu, Miina, van der Koog, Luke, Whittaker, Thomas E., Cunnane, Eoghan M., Silva, Andreia M., Dekker, Niek, Stevens, Molly M.

“… [Display omitted] Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting as delivery vehicles for molecular messages …”
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Advanced Therapeutic Dressings for Effective Wound Healing--A Review von Boateng, Joshua, Catanzano, Ovidio

“… Advanced therapeutic dressings that take active part in wound healing to achieve rapid and complete healing of chronic wounds is of current research interest …”
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Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source von Meng, Wanrong, He, Chuanshi, Hao, Yaying, Wang, Linlin, Li, Ling, Zhu, Guiquan

“… Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are nanosized membrane vesicles derived from most cell types. Carrying …”
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Exosome engineering in cell therapy and drug delivery von Sadeghi, Somaye, Tehrani, Fahimeh Ramezani, Tahmasebi, Safa, Shafiee, Abbas, Hashemi, Seyed Mahmoud

“… Cell-derived exosomes have opened new horizons in modern therapy for advanced drug delivery and therapeutic applications, due to their key features such as low …”
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