Suchergebnisse - "Dolnik, Olga"

Assembly and transport of filovirus nucleocapsids von Dolnik, Olga, Becker, Stephan

“… Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is …”
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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells von Bestle, Dorothea, Heindl, Miriam Ruth, Limburg, Hannah, Van Lam van, Thuy, Pilgram, Oliver, Moulton, Hong, Stein, David A, Hardes, Kornelia, Eickmann, Markus, Dolnik, Olga, Rohde, Cornelius, Klenk, Hans-Dieter, Garten, Wolfgang, Steinmetzer, Torsten, Böttcher-Friebertshäuser, Eva

“… The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute infection of the respiratory tract (COVID-19) that can result in severe disease …”
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Mate choice is affected by parasite infestation rate of the choosing individual as well as of potential mating partners von Cantarero, Alejandro, Dolnik, Olga V, Griggio, Matteo, Hoi, Herbert

“… Abstract Parasites are known to be a key driving force in mate choice and are important for the expression and evolution of ornaments and behavioral traits …”
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Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances von Schudt, Gordian, Kolesnikova, Larissa, Dolnik, Olga, Sodeik, Beate, Becker, Stephan

“… Transport of large viral nucleocapsids from replication centers to assembly sites requires contributions from the host cytoskeleton via cellular adaptor and …”
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Biting midges (Ceratopogonidae) as vectors of avian trypanosomes von Svobodová, Milena, Dolnik, Olga V., Čepička, Ivan, Rádrová, Jana

“… Background Although avian trypanosomes are widespread parasites, the knowledge of their vectors is still incomplete. Despite biting midges (Diptera: …”
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New Perspectives on the Biogenesis of Viral Inclusion Bodies in Negative-Sense RNA Virus Infections von Dolnik, Olga, Gerresheim, Gesche K., Biedenkopf, Nadine

“… Infections by negative strand RNA viruses (NSVs) induce the formation of viral inclusion bodies (IBs) in the host cell that segregate viral as well as cellular …”
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Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability von Escudero-Pérez, Beatriz, Volchkova, Valentina A., Dolnik, Olga, Lawrence, Philip, Volchkov, Viktor E.

“… During Ebola virus (EBOV) infection a significant amount of surface glycoprotein GP is shed from infected cells in a soluble form due to cleavage by cellular …”
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Inclusion bodies are a site of ebolavirus replication von Hoenen, Thomas, Shabman, Reed S, Groseth, Allison, Herwig, Astrid, Weber, Michaela, Schudt, Gordian, Dolnik, Olga, Basler, Christopher F, Becker, Stephan, Feldmann, Heinz

“… Inclusion bodies are a characteristic feature of ebolavirus infections in cells. They contain large numbers of preformed nucleocapsids, but their biological …”
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Transport of Ebolavirus Nucleocapsids Is Dependent on Actin Polymerization: Live-Cell Imaging Analysis of Ebolavirus-Infected Cells von Schudt, Gordian, Dolnik, Olga, Kolesnikova, Larissa, Biedenkopf, Nadine, Herwig, Astrid, Becker, Stephan

“… Transport of ebolavirus (EBOV) nucleocapsids from perinuclear viral inclusions, where they are formed, to the site of budding at the plasma membrane represents …”
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Marburg virus inclusions: A virus-induced microcompartment and interface to multivesicular bodies and the late endosomal compartment von Dolnik, Olga, Stevermann, Lea, Kolesnikova, Larissa, Becker, Stephan

“… Filovirus infection of target cells leads to the formation of virally induced cytoplasmic inclusions that contain viral nucleocapsids at different stages of …”
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Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism von Koch, Benjamin, Filzmayer, Maximilian, Patyna, Sammy, Wetzstein, Nils, Lampe, Sebastian, Schmid, Tobias, Geiger, Helmut, Baer, Patrick C., Dolnik, Olga

“… •Marburg virus infects and replicates in primary human proximal tubular cells (PTC).•Transcriptome analyses at multiple time points revealed a profound …”
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Molecular insights into nucleocapsid assembly and transport in Marburg and Ebola viruses von Takamatsu, Yuki, Dolnik, Olga, Hirabayashi, Ai, Okamoto, Kenta, Kurashige, Tomomi, Shangfan, Hu, Oda Harumi, Catarina, Noda, Takeshi

“… This study provides crucial insights into the molecular mechanisms of nucleocapsid assembly and transport in filoviruses, specifically Marburg virus (MARV) and …”
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Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles von Dolnik, Olga, Kolesnikova, Larissa, Stevermann, Lea, Becker, Stephan

“… The nucleoprotein NP of Marburg virus (MARV) is the major component of the viral nucleocapsid, which also consists of the viral proteins VP35, L, and VP30, as …”
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High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus von Scheuplein, Vivian A, Seifried, Janna, Malczyk, Anna H, Miller, Lilija, Höcker, Lena, Vergara-Alert, Júlia, Dolnik, Olga, Zielecki, Florian, Becker, Björn, Spreitzer, Ingo, König, Renate, Becker, Stephan, Waibler, Zoe, Mühlebach, Michael D

“… The Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as the causative agent of a severe respiratory disease with a fatality rate of …”
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Interaction with Tsg101 Is Necessary for the Efficient Transport and Release of Nucleocapsids in Marburg Virus-Infected Cells von Dolnik, Olga, Kolesnikova, Larissa, Welsch, Sonja, Strecker, Thomas, Schudt, Gordian, Becker, Stephan

“… Endosomal sorting complex required for transport (ESCRT) machinery supports the efficient budding of Marburg virus (MARV) and many other enveloped viruses …”
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Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage von Bestle, Dorothea, Bittel, Linda, Werner, Anke-Dorothee, Kämper, Lennart, Dolnik, Olga, Krähling, Verena, Steinmetzer, Torsten, Böttcher-Friebertshäuser, Eva

“… •The necessity of EBOV GP cleavage at the furin cleavage site was and is a subject of debate.•The furin cleavage site mutant EBOV GP_AGTAA, which was described …”
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A live-cell imaging system for visualizing the transport of Marburg virus nucleocapsid-like structures von Takamatsu, Yuki, Dolnik, Olga, Noda, Takeshi, Becker, Stephan

“… Background Live-cell imaging is a powerful tool for visualization of the spatio-temporal dynamics of moving signals in living cells. Although this technique …”
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Genomic RNA editing and its impact on Ebola virus adaptation during serial passages in cell culture and infection of guinea pigs von Volchkova, Valentina A, Dolnik, Olga, Martinez, Miguel J, Reynard, Olivier, Volchkov, Viktor E

“… Synthesis of the structural, surface glycoprotein (GP) of Ebola virus (EBOV) is dependent on transcriptional RNA editing phenomenon. Editing results in the …”
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Individual Oocysts of Isospora (Apicomplexa: Coccidia) Parasites From Avian Feces: From Photo to Sequence von Dolnik, Olga V., Palinauskas, Vaidas, Bensch, Staffan

“… Numerous microscopic studies of coccidian oocysts from avian feces have become the basis for species identification. In contrast, molecular studies of wild …”
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Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013 von Bukreyev, Alexander A, Chandran, Kartik, Dolnik, Olga, Dye, John M, Ebihara, Hideki, Leroy, Eric M, Mühlberger, Elke, Netesov, Sergey V, Patterson, Jean L, Paweska, Janusz T, Saphire, Erica Ollmann, Smither, Sophie J, Takada, Ayato, Towner, Jonathan S, Volchkov, Viktor E, Warren, Travis K, Kuhn, Jens H

“… The International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group prepares proposals on the classification and nomenclature of filoviruses to …”
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