Suchergebnisse - "Doerdelmann, Cyril"
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Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 28.11.2023Veröffentlicht in Nature communications (28.11.2023)“… Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the …”
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Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels
ISSN: 0305-1048, 1362-4962, 1362-4962Veröffentlicht: Oxford University Press 22.09.2023Veröffentlicht in Nucleic acids research (22.09.2023)“… Though the effect of the recently identified mitochondrial NAD+ transporter SLC25A51 on glucose metabolism has been described, its contribution to other …”
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Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
ISSN: 1097-4164, 1097-4164Veröffentlicht: United States 03.11.2022Veröffentlicht in Molecular cell (03.11.2022)“… Stem cell division is linked to tumorigenesis by yet-elusive mechanisms. The hematopoietic system reacts to stress by triggering hematopoietic stem and …”
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