Výsledky vyhľadávania - "Dighe, Vikas"

Targeted delivery of ursolic acid and oleanolic acid to lungs in the form of an inhaler for the management of tuberculosis: Pharmacokinetic and toxicity assessment Autor Saini, Vinay, Debnath, Sujit Kumar, Maske, Priyanka, Dighe, Vikas, Srivastava, Rohit

“…Ursolic acid (UA) and oleanolic acid (OA) are triterpenoids. They are used to treat numerous diseases, including tuberculosis. Combinations of these drugs…”
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Rifampicin Lipid-Polymer hybrid nanoparticles (LIPOMER) for enhanced Peyer’s patch uptake Autor Bachhav, Sagar S., Dighe, Vikas D., Kotak, Darsheen, Devarajan, Padma V.

“…[Display omitted] The oral uptake of intact nanocarriers through Peyer’s patches is an important uptake pathway. We report Rifampicin Lipid-Polymer hybrid…”
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Exploring Peyer's Patch Uptake as a Strategy for Targeted Lung Delivery of Polymeric Rifampicin Nanoparticles Autor Bachhav, Sagar S, Dighe, Vikas D, Devarajan, Padma V

“…Uptake of nanoparticles through Peyer's Patches following oral administration could enable translocation through lymph to lymphatic organs like the lungs. An…”
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Hypermethylation of estrogen receptor promoter region in adult testis of rats exposed neonatally to bisphenol A Autor Doshi, Tanvi, Mehta, Smita Salian, Dighe, Vikas, Balasinor, Nafisa, Vanage, Geeta

“…Bisphenol A (BPA) is an estrogenic endocrine disruptor commonly used in manufacture of polycarbonate plastics and epoxy resins. Due to its ubiquitous presence…”
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Targeted delivery of ursolic acid and oleanolic acid to lungs in the form of an inhaler for the management of tuberculosis: Pharmacokinetic and toxicity assessment Autor Vinay Saini, Sujit Kumar Debnath, Priyanka Maske, Vikas Dighe, Rohit Srivastava

“…Introduction Ursolic acid (UA) and oleanolic acid (OA) are triterpenoids. They are used to treat numerous diseases, including tuberculosis. Combinations of…”
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Long-Acting Efavirenz and HIV-1 Fusion Inhibitor Peptide Co-loaded Polymer-Lipid Hybrid Nanoparticles: Statistical Optimization, Cellular Uptake, and In Vivo Biodistribution Autor Surve, Dhanashree H, Jirwankar, Yugandhara B, Dighe, Vikas D, Jindal, Anil B

“…The objective of the present study was to develop long-acting efavirenz (Efa)-enfuvirtide (Enf) Co-loaded polymer-lipid hybrid nanoparticles (PLN) with…”
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Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric Nanorods Autor Bhide, Atharva R, Suri, Mansi, Katnoria, Sapna, Kaur, Sukhbir, Jirwankar, Yugandhara B, Dighe, Vikas D, Jindal, Anil B

“…Artemether oily injection is recommended for the treatment of severe malaria by the intramuscular route. The major limitations of the artemisinin combination…”
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Neuroprotective Effect of Coumarin Nasal Formulation: Kindling Model Assessment of Epilepsy Autor Muke, Suraj, Kaikini, Aakruti, Peshattiwar, Vaibhavi, Bagle, Sneha, Dighe, Vikas, Sathaye, Sadhana

“…Epilepsy is a brain disorder characterized by sudden recurrent seizures. Considering the fact that epileptogenesis is a process that affects the quality of…”
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Bisphenol A-induced ultrastructural changes in the testes of common marmoset Autor Vijaykumar, Tushara, Singh, Dipty, Vanage, Geeta R., Dhumal, Rohit V., Dighe, Vikas D.

“…Bisphenol A (BPA) is an endocrine disruptor that is widely used in the manufacture of polycarbonate plastics, epoxy resins and dental sealants. It is known to…”
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Effect of melatonin on bovine sperm characteristics and ultrastructure changes following cryopreservation Autor ChaithraShree, A. R., Ingole, Shailesh D., Dighe, Vikas D., Nagvekar, Anagha S., Bharucha, Simin V., Dagli, Nilesh R., Kekan, Prakash M., Kharde, Shambhudeo D.

“…The production of reactive oxygen species (ROS) during cryopreservation of semen alters the sperm motion and mobility characteristics, resulting in poor or…”
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Erratum to ‘Rifampicin Lipid-Polymer hybrid nanoparticles (LIPOMER) for enhanced Peyer’s patch uptake’ [International Journal of Pharmaceutics 532 (2017) 612–622] Autor Bachhav, Sagar S., Dighe, Vikas D., Kotak, Darsheen, Devarajan, Padma V.

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Rapid label-free visual assay for the detection and quantification of viral RNA using peptide nucleic acid (PNA) and gold nanoparticles (AuNPs) Autor Joshi, Vinay G., Chindera, Kantaraja, Singh, Arvind Kumar, Sahoo, Aditya P., Dighe, Vikas D., Thakuria, Dimpal, Tiwari, Ashok K., Kumar, Satish

“…•Simple and easy to use visual assay for viral diagnosis.•It is rapid and label-free assay with pen-side diagnostic applications.•The assay shows high…”
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Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases Autor Joshi, Vinay Ganeshrao, Dighe, Vikas D., Thakuria, Dimpal, Malik, Yashpal Singh, Kumar, Satish

“…The peptide dendrimer provides novel strategies for various biological applications. Assembling of peptide in macromolecular structure is expected to give…”
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Antimycobacterial Activity of Solid Lipid Microparticles Loaded with Ursolic Acid and Oleanolic Acid: In Vitro, In Vivo, and Toxicity Assessments Autor Saini, Vinay, Mata Espinosa, Dulce, Pandey, Alok, Dighe, Vikas, Barrios Payán, Jorge, Prasad Myneedu, Vithal, Valdez Zarate, Ivan, Rajani, Dhanji P., Anande, Lalit D., Hernandez Pando, Rogelio, Srivastava, Rohit

“…Ursolic acid (UA) and oleanolic acid (OA) are hydrophobic triterpenoid isomers with demonstrated anti-mycobacterial (Mtb) and immune-regulatory properties,…”
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Novel Technique of Vaginoplasty Developing Normal Vagina, Role of Stemness Markers and Translational Genes Autor Mhatre, Pravin, Dighe, Vikas, Das, Dhanjit, Pawar, Amol

“…Aims and Objectives: To study development of neo-vagina by metaplastic conversion of peritoneum, To identify translational Stemness markers using…”
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The modulatory role of phloretin in Aβ25–35 induced sporadic Alzheimer’s disease in rat model Autor Ghumatkar, Priya J., Patil, Sachin P., Peshattiwar, Vaibhavi, Vijaykumar, Tushara, Dighe, Vikas, Vanage, Geeta, Sathaye, Sadhana

“…Alzheimer’s disease (AD) is the leading neurodegenerative disorder with extracellular senile plaques and neurofibrillary tangles as the major hallmarks. The…”
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Heterozygous Embryonic Stem Cell Lines Derived from Nonhuman Primate Parthenotes Autor Dighe, Vikas, Clepper, Lisa, Pedersen, Darlene, Byrne, James, Ferguson, Betsy, Gokhale, Sumita, Penedo, M. Cecilia T., Wolf, Don, Mitalipov, Shoukhrat

“…Monoparental parthenotes represent a potential source of histocompatible stem cells that should be isogenic with the oocyte donor and therefore suitable for…”
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Epigenetic Reprogramming by Somatic Cell Nuclear Transfer in Primates Autor Sparman, Michelle, Dighe, Vikas, Sritanaudomchai, Hathaitip, Ma, Hong, Ramsey, Cathy, Pedersen, Darlene, Clepper, Lisa, Nighot, Prashant, Wolf, Don, Hennebold, Jon, Mitalipov, Shoukhrat

“…We recently demonstrated that somatic cells from adult primates could be reprogrammed into a pluripotent state by somatic cell nuclear transfer. However, the…”
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Identification and validation of Sertoli cell homing peptides as molecular steering for testis targeted drug delivery Autor Jirwankar, Yugandhara, Dighe, Vikas

“…The testicle, an organ privileged with immunity because of Blood-Testis Barrier (BTB), poses a major impediment to developing and delivering drugs to the…”
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Efficacy and safety of a herbo-mineral ayurvedic formulation ′Afrodet Plus®′ in male rats Autor Dhumal, Rohit, Vijaykumar, Tushara, Dighe, Vikas, Selkar, Nilakash, Chawda, Mukesh, Vahlia, Mahesh, Vanage, Geeta

“…Background: Reverse pharmacology for drug development has been highly productive and cost-effective in recent past as it is based on the documented therapeutic…”
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