Suchergebnisse - "Deshwal, Soni"

Mitochondrial Proteases: Multifaceted Regulators of Mitochondrial Plasticity von Deshwal, Soni, Fiedler, Kai Uwe, Langer, Thomas

“… Mitochondria are essential metabolic hubs that dynamically adapt to physiological demands. More than 40 proteases residing in different compartments of …”
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On the Clinical Pharmacology of Reactive Oxygen Species von Casas, Ana I, Nogales, Cristian, Mucke, Hermann A M, Petraina, Alexandra, Cuadrado, Antonio, Rojo, Ana I, Ghezzi, Pietro, Jaquet, Vincent, Augsburger, Fiona, Dufrasne, Francois, Soubhye, Jalal, Deshwal, Soni, Di Sante, Moises, Kaludercic, Nina, Di Lisa, Fabio, Schmidt, Harald H H W

“… Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet clinical exploitation of these hypotheses by pharmacological modulation …”
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Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression von Grotehans, Nils, McGarry, Lynn, Nolte, Hendrik, Xavier, Vanessa, Kroker, Moritz, Narbona‐Pérez, Álvaro Jesús, Deshwal, Soni, Giavalisco, Patrick, Langer, Thomas, MacVicar, Thomas

“… Replication of the mitochondrial genome and expression of the genes it encodes both depend on a sufficient supply of nucleotides to mitochondria. Accordingly, …”
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Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes von Deshwal, Soni, Forkink, Marleen, Hu, Chou-Hui, Buonincontri, Guido, Antonucci, Salvatore, Di Sante, Moises, Murphy, Michael P, Paolocci, Nazareno, Mochly-Rosen, Daria, Krieg, Thomas, Di Lisa, Fabio, Kaludercic, Nina

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Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes von Deshwal, Soni, Forkink, Marleen, Hu, Chou-Hui, Buonincontri, Guido, Antonucci, Salvatore, Di Sante, Moises, Murphy, Michael P, Paolocci, Nazareno, Mochly-Rosen, Daria, Krieg, Thomas, Di Lisa, Fabio, Kaludercic, Nina

“… Monoamine oxidase (MAO) inhibitors ameliorate contractile function in diabetic animals, but the mechanisms remain unknown. Equally elusive is the interplay …”
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Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection von Bøtker, Hans Erik, Hausenloy, Derek, Andreadou, Ioanna, Antonucci, Salvatore, Boengler, Kerstin, Davidson, Sean M., Deshwal, Soni, Devaux, Yvan, Di Lisa, Fabio, Di Sante, Moises, Efentakis, Panagiotis, Femminò, Saveria, García-Dorado, David, Giricz, Zoltán, Ibanez, Borja, Iliodromitis, Efstathios, Kaludercic, Nina, Kleinbongard, Petra, Neuhäuser, Markus, Ovize, Michel, Pagliaro, Pasquale, Rahbek-Schmidt, Michael, Ruiz-Meana, Marisol, Schlüter, Klaus-Dieter, Schulz, Rainer, Skyschally, Andreas, Wilder, Catherine, Yellon, Derek M., Ferdinandy, Peter, Heusch, Gerd

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Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7 von Deshwal, Soni, Onishi, Mashun, Tatsuta, Takashi, Bartsch, Tim, Cors, Eileen, Ried, Katharina, Lemke, Kathrin, Nolte, Hendrik, Giavalisco, Patrick, Langer, Thomas

“… Coenzyme Q (or ubiquinone) is a redox-active lipid that serves as universal electron carrier in the mitochondrial respiratory chain and antioxidant in the …”
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Emerging role of monoamine oxidase as a therapeutic target for cardiovascular disease von Deshwal, Soni, Di Sante, Moises, Di Lisa, Fabio, Kaludercic, Nina

“… •MAOs are major determinants of myocardial redox status.•Products of MAO activity target mitochondria to induce organelle dysfunction.•MAOs play a key role in …”
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Reactive oxygen species and redox compartmentalization von Kaludercic, Nina, Deshwal, Soni, Di Lisa, Fabio

“… Reactive oxygen species (ROS) formation and signaling are of major importance and regulate a number of processes in physiological conditions. A disruption in …”
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Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection von Bøtker, Hans Erik, Hausenloy, Derek, Andreadou, Ioanna, Antonucci, Salvatore, Boengler, Kerstin, Davidson, Sean M., Deshwal, Soni, Devaux, Yvan, Di Lisa, Fabio, Di Sante, Moises, Efentakis, Panagiotis, Femminò, Saveria, García-Dorado, David, Giricz, Zoltán, Ibanez, Borja, Iliodromitis, Efstathios, Kaludercic, Nina, Kleinbongard, Petra, Neuhäuser, Markus, Ovize, Michel, Pagliaro, Pasquale, Rahbek-Schmidt, Michael, Ruiz-Meana, Marisol, Schlüter, Klaus-Dieter, Schulz, Rainer, Skyschally, Andreas, Wilder, Catherine, Yellon, Derek M., Ferdinandy, Peter, Heusch, Gerd

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Glutamine sensing licenses cholesterol synthesis von Garcia, Bruna Martins, Melchinger, Philipp, Medeiros, Tania, Hendrix, Sebastian, Prabhu, Kavan, Corrado, Mauro, Kingma, Jenina, Gorbatenko, Andrej, Deshwal, Soni, Veronese, Matteo, Scorrano, Luca, Pearce, Erika, Giavalisco, Patrick, Zelcer, Noam, Pernas, Lena

“… The mevalonate pathway produces essential lipid metabolites such as cholesterol. Although this pathway is negatively regulated by metabolic intermediates, …”
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Antimicrobial peptides play a functional role in bumblebee anti-trypanosome defense von Deshwal, Soni, Mallon, Eamonn B.

“… Bumblebees, amongst the most important of pollinators, are under enormous population pressures. One of these is disease. The bumblebee and its gut trypanosome …”
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Monoamine oxidase A-dependent ROS formation modulates human cardiomyocyte differentiation through AKT and WNT activation von Di Sante, Moises, Antonucci, Salvatore, Pontarollo, Laura, Cappellaro, Ilaria, Segat, Francesca, Deshwal, Soni, Greotti, Elisa, Grilo, Luis F., Menabò, Roberta, Di Lisa, Fabio, Kaludercic, Nina

“… During embryonic development, cardiomyocytes undergo differentiation and maturation, processes that are tightly regulated by tissue-specific signaling …”
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Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis von Antonucci, Salvatore, Mulvey, John F., Burger, Nils, Di Sante, Moises, Hall, Andrew R., Hinchy, Elizabeth C., Caldwell, Stuart T., Gruszczyk, Anja V., Deshwal, Soni, Hartley, Richard C., Kaludercic, Nina, Murphy, Michael P., Di Lisa, Fabio, Krieg, Thomas

“… Reactive oxygen species (ROS) have an equivocal role in myocardial ischaemia reperfusion injury. Within the cardiomyocyte, mitochondria are both a major source …”
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Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression von Grotehans, Nils, Mcgarry, Lynn, Nolte, Hendrik, Kroker, Moritz, Alvaro Jesus Narbona-Perez, Soni Deshwal, Giavalisco, Patrick, Langer, Thomas, Macvicar, Thomas

“… Replication and expression of the mitochondrial genome depend on the sufficient supply of nucleotide building blocks to mitochondria. Dysregulated nucleotide …”
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Monoamine oxidase A deletion leads to autophagy inhibition and impairment in cardiomyocyte differentiation from hiPSCs von Di Sante, Moises, Antonucci, Salvatore, Greotti, Elisa, Mazza, Fabio, Troiano, Carmen, Deshwal, Soni, Menabò, Roberta, Di Lisa, Fabio, Kaludercic, Nina

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Measurement of Mitochondrial ROS Formation von Deshwal, Soni, Antonucci, Salvatore, Kaludercic, Nina, Di Lisa, Fabio

“… Reactive oxygen species (ROS) are involved in both physiological and pathological processes. This widely accepted concept is based more on the effects of …”
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Antimicrobial peptides play a functional role in bumblebee anti-trypanosome defense von Soni Deshwal, Mallon, Eamonn

“… Bumblebees, amongst the most important of pollinators, are under enormous population pressures. One of these is disease. The bumblebee and its gut trypanosome …”
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