Suchergebnisse - "Decollogny, Morgane"
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Persisting cancer cells are different from bacterial persisters
ISSN: 2405-8025, 2405-8025Veröffentlicht: United States 01.05.2024Veröffentlicht in Trends in cancer (01.05.2024)“… The persistence of drug-sensitive tumors poses a significant challenge in cancer treatment. The concept of bacterial persisters, which are a subpopulation of …”
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H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 24.05.2024Veröffentlicht in Nature communications (24.05.2024)“… Histone H2AX plays a key role in DNA damage signalling in the surrounding regions of DNA double-strand breaks (DSBs). In response to DNA damage, H2AX becomes …”
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Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
ISSN: 2767-9764, 2767-9764Veröffentlicht: United States American Association for Cancer Research 26.10.2022Veröffentlicht in Cancer research communications (26.10.2022)“… In recent years, platinum (Pt) drugs have been found to be especially efficient to treat patients with cancers that lack a proper DNA damage response, for …”
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Spatiotemporal organisation of residual disease in mouse and human BRCA1-deficient mammary tumours and breast cancer
ISSN: 2692-8205Veröffentlicht: Cold Spring Harbor Laboratory 03.04.2025Veröffentlicht in bioRxiv (03.04.2025)“… Breast cancer remains one of the prominent causes of death worldwide. Although chemotherapeutic agents often result in substantial reduction of primary or …”
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