Výsledky vyhledávání - "Data Science/Biostatistics/Informatics"

44499 Heterogeneity of treatment effect among patients with type 2 diabetes and body mass index >=27kg/m² in the Jump Start Study Autor Kobe, Elizabeth A., Crowley, Mathew J., Jeffreys, Amy, Yancy, William S., Zervakis, Jennifer, Edelman, David E., Coffman, Cynthia J.

“…ABSTRACT IMPACT: This is the first study to use QUINT analyses to examine heterogeneity of treatment effect for group medical visits among individuals with…”
Získat plný text

82125 Multiple epidemics of multidrug-resistant tuberculosis revealed by spatial disease mapping and whole-genome sequencing analysis in urban China Autor Yang, Chongguang, Zhang, Yangyi, Jiang, Yuan, Wu, Zheyuan, Shen, Xin, Warren, Joshua L., Cohen, Ted

“…ABSTRACT IMPACT: Our study will integrate state-of-the-art methods in pathogen genomics, epidemiology, and geospatial analysis to identify both host- and…”
Získat plný text

00001 Demographic disparities in proximity to stroke care in the United States Autor Yu, Cathy Y., Blaine, Timothy, Panagos, Peter, Kansagra, Akash P.

“…ABSTRACT IMPACT: Given the association between lower time to treatment and better clinical outcomes in stroke patients, identifying factors correlated with…”
Získat plný text

42855 A Phenomics Approach to the Categorization and Refinement of Heart Failure Autor Reza, Nosheen, Bone, William, Singhal, Pankhuri, Verma, Anurag, Murthy, Ashwin C., Denduluri, Srinivas, Adusumalli, Srinath, Ritchie, Macrylyn D., Cappola, Thomas P.

“…ABSTRACT IMPACT: Measuring and analyzing qualitative and quantitative traits using phenomics approaches will yield previously unrecognized heart failure…”
Získat plný text

12621 Targeted Chemical-Genetic Screen Platform for Identifying Drug Modes-of-Action Autor Lin, Kevin, Billmann, Maximilian, Ward, Henry, Chang, Ya-Chu, Bielinsky, Anja-Katrin, Myers, Chad L.

“…ABSTRACT IMPACT: The key to advancing precision medicine is to deepen our understanding of drug modes-of-action (MOA). This project aims to develop a novel…”
Získat plný text

23255 Devices Engineered to Collect Exhaled Breath Condensate (EBC) and their Applications Autor Schmidt, Alexander J., Borras, Eva, Nguyen, Anh, Kenyon, Nicholas J., Davis, Cristina E.

“…ABSTRACT IMPACT: Human exhaled breath is rich in metabolomic content that represents pulmonary function and gas exchange with blood, which can provide insights…”
Získat plný text

77232 The role of the bromodomain and extra-terminal motif (BET) family of proteins in head and neck cancer tumorigenic phenotype Autor Sample, Reilly A., Paolini, Rachel

“…ABSTRACT IMPACT: Understanding the biology underpinning head and neck cancer invasion and metastasis could lead to novel targeted therapies that are both…”
Získat plný text

27337 Characterizing Temporal Patterns in Glucose Dysregulation Following SARS-CoV-2 Infection Autor Mistry, Sejal, Gouripeddi, Ramkiran, Facelli, Julio C.

“…ABSTRACT IMPACT: Understanding the longitudinal glucose changes following SARS-CoV-2 infection can inform point-of-care guidelines and elucidate the viral…”
Získat plný text

63438 Differential chromatin accessibility at dorsal root ganglia enhancers is associated with nerve injury Autor Stephens, Kimberly E., Zhou, Weiqiang, Ji, Zhicheng, Ji, Hongkai, Guan, Yun, Taverna, Sean D.

“…ABSTRACT IMPACT: Our improved understanding of the changes in chromatin accessibility that occur in persistent pain states may identify regulatory genomic…”
Získat plný text

10227 A Framework for Bringing Secondary Analysis of EHR Data to Geographically Dispersed Clinician Scientists Autor McClay, James, Anzalone, Jerrod, Geary, Carol, Zhang, Ying

“…ABSTRACT IMPACT: The described framework will enable other sites with a well-defined apparatus for enabling the secondary analysis of EHR data for research…”
Získat plný text

89976 ASSESSING PROTEIN BIOMARKERS ROLE IN CVD RISK PREDICTION IN PERSONS LIVING WITH HIV (PWH) Autor Safo, Sandra, Haine, Lillian, Baker, Jason, Reilly, Cavan, Duprez, Daniel, Neaton, Jim, Wang, Jiuzhou, Jain, Mamta K., Pinto, Alejandro Arenas, Staub, Therese, Polizzotto, Mark

“…ABSTRACT IMPACT: Our findings could potentially identify CVD at-risk persons living with HIV who might benefit from aggressive risk-reduction…”
Získat plný text

26600 HiTech and Health Interest Trends in Rural Neighborhoods are Associated with COVID-19 Autor Greer, Melody

“…ABSTRACT IMPACT: Current, complete, unbiased, and accurate information, which includes patient social and environmental context, is necessary to understand…”
Získat plný text

74325 Vast sex-specific differences in transcriptional landscapes of pancreatic neuroendocrine tumors Autor Ivanov, Nikolay A., Fahey, Thomas J., Mason, Christopher E., Min, Irene M.

“…ABSTRACT IMPACT: Here, we describe extensive sex-specific differences in the transcriptomes of pancreatic neuroendocrine tumors (PNETs). Given that the…”
Získat plný text

30432 Novel insights from single-cell RNAseq analysis of the stromavascular fraction of human adipose tissue Autor Wang, Bingyao, Smith, Gregory, Ruf-Zamojski, Frederique, Lee, Gyu Ho, Sealfon, Stuart C., Albu, Jeanine, Fried, Susan K., Karastergiou, Kalypso

“…ABSTRACT IMPACT: Characterizing the cellular composition of human adipose tissue may contribute to the prevention and/or treatment of obesity-associated…”
Získat plný text

83649 Modeling COVID-19 infection dynamics and program interventions for K-12 school re-opening Autor Morrison, Douglas E., Nianogo, Roch, Manuel, Vladimir G., Arah, Onyebuchi A., Anderson, Nathaniel, Kuo, Tony, Inkelas, Moira

“…ABSTRACT IMPACT: This study provides public health and K-12 school districts with a pragmatic, flexible, adaptable model showing COVID-19 transmission…”
Získat plný text

31115 Perimetric resilience in the retina: spatial distribution of preserved peripheral visual field loci in retinitis pigmentosa Autor Vongsachang, Hursuong, Patel, Tapan, Kong, Xiangrong, Singh, Mandeep S.

“…ABSTRACT IMPACT: We developed a novel semi-automated computational platform to quantify spatial characteristics of preserved peripheral visual field loci in…”
Získat plný text

74123 A Learning Health Systems approach using health record data to construct patient frailty scores and predict safety events Autor Bokov, Alex, Espinoza, Sara, Tripathy, Chandana, Stevens, Kathleen

“…ABSTRACT IMPACT: Laying the groundwork for better predictive algorithms to inform clinical decisions and planning. OBJECTIVES/GOALS: Frailty scores predict…”
Získat plný text

16461 Comparison of voxel intensity standardization methods in head and neck cancer magnetic resonance imaging Autor Wahid, Kareem A., He, Renjie, McDonald, Brigid A., Anderson, Brian M., Salzillo, Travis, Mulder, Sam, Wang, Jarey, Sharafi, Christina Setareh, McCoy, Lance A., Naser, Mohamed A., Ahmed, Sara, Sanders, Keith L., Mohamed, Abdallah S.R., Ding, Yao, Wang, Jihong, Hutcheson, Kate, Lai, Stephen Y., Fuller, Clifton D., van Dijk, Lisanne V.

“…ABSTRACT IMPACT: This work will standardize necessary image pre-processing for diagnostic and prognostic clinical workflows dependent on quantitative analysis…”
Získat plný text

91726 Screening for Obesity related renal damage in adolescent women - Body Surface area matters Autor Bielopolski, D., Singh, N., Bentur, O.S., Renert-Yuval, Y., MacArthur, R., Vasquez, K., Moftah, D.S., Vaughan, R.D., Kost, R.G., Tobin, J.N.

“…ABSTRACT IMPACT: This change will improve primary care physicians and pediatrics ability to identify, intervene and prevent obesity related renal damage in the…”
Získat plný text

20184 A Hypothesis-Driven Parametric Study of a Computational Dermal Replacement Model Autor Sohutskay, David, Tepole, Adrian Buganza, Voytik-Harbin, Sherry

“…ABSTRACT IMPACT: This work will be used to improve the design of engineered dermal replacements that can be used to treat difficult-to-heal wounds such as…”
Získat plný text